Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Section of Endocrinology

52 publications found

Aune D, Mahamat-Saleh Y, Norat T, Riboli E (2020)
High Body Mass Index and Central Adiposity Is Associated with Increased Risk of Acute Pancreatitis: A Meta-Analysis
Dig Dis Sci
DOI 10.1007/s10620-020-06275-6, PubMed 32556971

Aune D, Schlesinger S, Hamer M, Norat T, Riboli E (2020)
Physical activity and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies
BMC Cardiovasc Disord, 20 (1), 318
DOI 10.1186/s12872-020-01531-z, PubMed 32631241

Birkeland KI, Bodegard J, Banerjee A, Kim DJ, Norhammar A, Eriksson JW, Thuresson M, Okami S, Ha KH, Kossack N, Mamza JB, Zhang R, Yajima T, Komuro I, Kadowaki T (2020)
Lower Cardiorenal Risk with Sodium-Glucose Cotransporter-2 Inhibitors versus Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Patients without Cardiovascular and Renal Diseases: A large multinational observational study
Diabetes Obes Metab (in press)
DOI 10.1111/dom.14189, PubMed 32893440

Birkeland KI, Bodegard J, Eriksson JW, Norhammar A, Haller H, Linssen GCM, Banerjee A, Thuresson M, Okami S, Garal-Pantaler E, Overbeek J, Mamza JB, Zhang R, Yajima T, Komuro I, Kadowaki T (2020)
Heart failure and chronic kidney disease manifestation and mortality risk associations in type 2 diabetes: A large multinational cohort study
Diabetes Obes Metab, 22 (9), 1607-1618
DOI 10.1111/dom.14074, PubMed 32363737

Bollerslev J, Sjöstedt E, Rejnmark L (2020)
Cardiovascular consequences of parathyroid disorders in adults
Ann Endocrinol (Paris) (in press)
DOI 10.1016/j.ando.2020.02.003, PubMed 32192790

Bornstedt ME, Gjerlaugsen N, Olstad OK, Berg JP, Bredahl MK, Thorsby PM (2020)
Vitamin D metabolites influence expression of genes concerning cellular viability and function in insulin producing β-cells (INS1E)
Gene, 746, 144649
DOI 10.1016/j.gene.2020.144649, PubMed 32251702

Bøhmer T, Bachtyari Z, Sommer C, Hammerstad SS (2020)
Auto regulatory capacity of the thyroid gland after numerous iodinated contrast media investigations
Scand J Clin Lab Invest, 80 (3), 191-195
DOI 10.1080/00365513.2019.1709658, PubMed 31990217

Chahal-Kummen M, Salte OBK, Hewitt S, Blom-Høgestøl IK, Risstad H, Kristinsson J, Mala T (2020)
Health benefits and risks during 10 years after Roux-en-Y gastric bypass
Surg Endosc
DOI 10.1007/s00464-019-07328-2, PubMed 31993812

Defreyne J, Aers XP, Collet SM, Wiepjes CM, Fisher AD, Schreiner T, Den Heijer M, Kaufman JM, T'Sjoen GGR (2020)
Lower Serum Estradiol Levels in Assigned Female at Birth Transgender People with Initiation of Testosterone Therapy: Results from the European Network for the Investigation of Gender Incongruence
LGBT Health, 7 (2), 71-81
DOI 10.1089/lgbt.2019.0260, PubMed 32049583

Defreyne J, Vanwonterghem Y, Collet S, Iwamoto SJ, Wiepjes CM, Fisher AD, Schreiner T, Heijer MD, T'Sjoen G (2020)
Vaginal bleeding and spotting in transgender men after initiation of testosterone therapy: A prospective cohort study (ENIGI)
Int J Transgend Health, 21 (2), 163-175
PubMed 32935087

Eidet JR, Jørstad ØK, Fostad IG, Olstad OK, Sørland RØ, Moe MC, Petrovski G, Pepaj M (2020)
Unilateral acute anterior uveitis is associated with ipsilateral changes in the tear fluid proteome that involves the LXR/RXR pathway
J Ophthalmic Inflamm Infect, 10 (1), 13
DOI 10.1186/s12348-020-00204-4, PubMed 32458144

Gatto F, Perez-Rivas LG, Olarescu NC, Khandeva P, Chachlaki K, Trivellin G, Gahete MD, Cuny T, on behalf of the ENEA Young Researchers Committee (EYRC) (2020)
Diagnosis and Treatment of Parasellar Lesions
Neuroendocrinology, 110 (9-10), 728-739
DOI 10.1159/000506905, PubMed 32126547

Gittoes NJ, Criseno S, Appelman-Dijkstra NM, Bollerslev J, Canalis E, Rejnmark L, Hassan-Smith Z (2020)
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of calcium metabolic disorders and osteoporosis
Eur J Endocrinol, 183 (2), G57-G65
DOI 10.1530/EJE-20-0385, PubMed 32396134

Giugliano RP, Pedersen TR, Saver JL, Sever PS, Keech AC, Bohula EA, Murphy SA, Wasserman SM, Honarpour N, Wang H, Lira Pineda A, Sabatine MS, FOURIER Investigators (2020)
Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis
Stroke, 51 (5), 1546-1554
DOI 10.1161/STROKEAHA.119.027759, PubMed 32312223

Giustina A, Adler RA, Binkley N, Bollerslev J, Bouillon R, Dawson-Hughes B, Ebeling PR, Feldman D, Formenti AM, Lazaretti-Castro M, Marcocci C, Rizzoli R, Sempos CT, Bilezikian JP (2020)
Consensus statement from 2nd International Conference on Controversies in Vitamin D
Rev Endocr Metab Disord, 21 (1), 89-116
DOI 10.1007/s11154-019-09532-w, PubMed 32180081

Hansen AMB, Wium C, Lee S, Tierney AC, McCarthy D, Roche HM, Drevon CA, Birkeland KI, Gulseth HL (2020)
Substantial inter-individual variations in insulin secretion and sensitivity across the glucometabolic spectrum
Scand J Clin Lab Invest, 80 (4), 282-290
DOI 10.1080/00365513.2020.1730433, PubMed 32134347

Hewitt S, Kristinsson J, Aasheim ET, Blom-Høgestøl IK, Aaseth E, Jahnsen J, Eriksen EF, Mala T (2020)
Relationships Between Vitamin D Status and PTH over 5 Years After Roux-en-Y Gastric Bypass: a Longitudinal Cohort Study
Obes Surg, 30 (9), 3426-3434
DOI 10.1007/s11695-020-04582-5, PubMed 32306297

Holte KB, Svanteson M, Hanssen KF, Sveen KA, Seljeflot I, Solheim S, Sell DR, Monnier VM, Berg TJ (2020)
Collagen methionine sulfoxide and glucuronidine/LW-1 are markers of coronary artery disease in long-term survivors with type 1 diabetes. The Dialong study
PLoS One, 15 (5), e0233174
DOI 10.1371/journal.pone.0233174, PubMed 32401813

Jain R, Özgümüş T, Jensen TM, du Plessis E, Keindl M, Møller CL, Falhammar H, Nyström T, Catrina SB, Jörneskog G, Jessen LE, Forsblom C, Haukka JK, Groop PH, Rossing P, Groop L, Eliasson M, Eliasson B, Brismar K, Al-Majdoub M, Nilsson PM, Taskinen MR, Ferrannini E, Spégel P, Berg TJ et al. (2020)
Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes
Sci Rep, 10 (1), 11561
DOI 10.1038/s41598-020-68130-y, PubMed 32665614

Juvodden HT, Viken MK, Nordstrand SEH, Viste R, Westlye LT, Thorsby PM, Lie BA, Knudsen-Heier S (2020)
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740

Kelly CB, Wagner CL, Shary JR, Leyva MJ, Yu JY, Jenkins AJ, Nankervis AJ, Hanssen KF, Garg SK, Scardo JA, Hammad SM, Aston CE, Lyons TJ (2020)
Vitamin D Metabolites and Binding Protein Predict Preeclampsia in Women with Type 1 Diabetes
Nutrients, 12 (7)
DOI 10.3390/nu12072048, PubMed 32664257

Kherad O, Peiffer-Smadja N, Karlafti L, Lember M, Aerde NV, Gunnarsson O, Baicus C, Vieira MB, Vaz-Carneiro A, Brucato A, Lazurova I, Leśniak W, Hanslik T, Hewitt S, Papanicolaou E, Boeva O, Dicker D, Ivanovska B, Yldiz P, Lacor P, Cranston M, Weidanz F, Costantino G, Montano N (2020)
The challenge of implementing Less is More medicine: A European perspective
Eur J Intern Med, 76, 1-7
DOI 10.1016/j.ejim.2020.04.014, PubMed 32303454

Kohsaka S, Lam CSP, Kim DJ, Cavender MA, Norhammar A, Jørgensen ME, Birkeland KI, Holl RW, Franch-Nadal J, Tangri N, Shaw JE, Ilomäki J, Karasik A, Goh SY, Chiang CE, Thuresson M, Chen H, Wittbrodt E, Bodegård J, Surmont F, Fenici P, Kosiborod M, CVD-REAL 2 Investigators and Study Group (2020)
Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study
Lancet Diabetes Endocrinol, 8 (7), 606-615
DOI 10.1016/S2213-8587(20)30130-3, PubMed 32559476

Kolnes AJ, Øystese KA, Dahlberg D, Berg-Johnsen J, Niehusmann P, Pahnke J, Bollerslev J, Jørgensen AP (2020)
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma
Acta Neurochir (Wien), 162 (4), 845-852
DOI 10.1007/s00701-019-04068-z, PubMed 31907611

Kolnes AJ, Øystese KAB, Olarescu NC, Ringstad G, Berg-Johnsen J, Casar-Borota O, Bollerslev J, Jørgensen AP (2020)
FSH Levels Are Related to E-cadherin Expression and Subcellular Location in Nonfunctioning Pituitary Tumors
J Clin Endocrinol Metab, 105 (8)
DOI 10.1210/clinem/dgaa281, PubMed 32421791

Kvammen JA, Thomassen RA, Kjeserud CN, Sæland C, Godang K, Bollerslev J, Thorsby PM, Juliusson PB, Bentsen BS, Henriksen C (2020)
Bone mineral density and vitamin D in paediatric intestinal failure patients receiving home parenteral nutrition
Clin Nutr ESPEN, 39, 234-241
DOI 10.1016/j.clnesp.2020.06.006, PubMed 32859323

Mahamat-Saleh Y, Aune D, Schlesinger S (2020)
25-Hydroxyvitamin D status, vitamin D intake, and skin cancer risk: a systematic review and dose-response meta-analysis of prospective studies
Sci Rep, 10 (1), 13151
DOI 10.1038/s41598-020-70078-y, PubMed 32753685

Molvaer AK, Iversen MM, Igland J, Peyrot M, Tell GS, Holte KB, Berg TJ (2020)
Higher levels of bodily pain in people with long-term type 1 diabetes: associations with quality of life, depressive symptoms, fatigue and glycaemic control - the Dialong study
Diabet Med, 37 (9), 1569-1577
DOI 10.1111/dme.14331, PubMed 32446279

Naudin S, Solans Margalef M, Saberi Hosnijeh F, Nieters A, Kyrø C, Tjønneland A, Dahm CC, Overvad K, Mahamat-Saleh Y, Besson C, Boutron-Ruault MC, Kühn T, Canzian F, Schulze MB, Peppa E, Karakatsani A, Trichopoulou A, Sieri S, Masala G, Panico S, Tumino R, Ricceri F, Chen SLF, Barroso LL, Huerta JM et al. (2020)
Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study
Int J Cancer, 147 (6), 1649-1656
DOI 10.1002/ijc.32977, PubMed 32176325

Nie J, Wang J, Aune D, Huang W, Xiao D, Wang Y, Chen X (2020)
Association between employment status and risk of all-cause and cause-specific mortality: a population-based prospective cohort study
J Epidemiol Community Health, 74 (5), 428-436
DOI 10.1136/jech-2019-213179, PubMed 32086372

Nordstrand SEH, Juvodden HT, Viste R, Rootwelt T, Karlsen TI, Thorsby PM, Swanson D, Nilsen KB, Hansen BH, Knudsen-Heier S (2020)
Obesity and other medical comorbidities among NT1 patients after the Norwegian H1N1 influenza epidemic and vaccination campaign
Sleep, 43 (5)
DOI 10.1093/sleep/zsz277, PubMed 31724727

Norum KR, Remaley AT, Miettinen HE, Strøm EH, Balbo BEP, Sampaio CATL, Wiig I, Kuivenhoven JA, Calabresi L, Tesmer JJ, Zhou M, Ng DS, Skeie B, Karathanasis SK, Manthei KA, Retterstøl K (2020)
Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings
J Lipid Res, 61 (8), 1142-1149
DOI 10.1194/jlr.S120000720, PubMed 32482717

Olsen T, Øvrebø B, Haj-Yasein N, Lee S, Svendsen K, Hjorth M, Bastani NE, Norheim F, Drevon CA, Refsum H, Vinknes KJ (2020)
Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study
J Transl Med, 18 (1), 122
DOI 10.1186/s12967-020-02288-x, PubMed 32160926

Opsahl JO, Moen GH, Qvigstad E, Böttcher Y, Birkeland KI, Sommer C (2020)
Epigenetic signatures associated with maternal body mass index or gestational weight gain: a systematic review
J Dev Orig Health Dis, 1-11 (in press)
DOI 10.1017/S2040174420000811, PubMed 32873364

Representatives of the Global Familial Hypercholesterolemia Community, Wilemon KA, Patel J, Aguilar-Salinas C, Ahmed CD, Alkhnifsawi M, Almahmeed W, Alonso R, Al-Rasadi K, Badimon L, Bernal LM, Bogsrud MP, Braun LT, Brunham L, Catapano AL, Cillíková K, Corral P, Cuevas R, Defesche JC, Descamps OS, de Ferranti S, Eiselé JL, Elikir G, Folco E, Freiberger T et al. (2020)
Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action
JAMA Cardiol, 5 (2), 217-229
DOI 10.1001/jamacardio.2019.5173, PubMed 31895433

Roland MCP, Lekva T, Godang K, Bollerslev J, Henriksen T (2020)
Changes in maternal blood glucose and lipid concentrations during pregnancy differ by maternal body mass index and are related to birthweight: A prospective, longitudinal study of healthy pregnancies
PLoS One, 15 (6), e0232749
DOI 10.1371/journal.pone.0232749, PubMed 32574162

Rubin KH, Möller S, Choudhury A, Zorina O, Kalsekar S, Eriksen EF, Andersen M, Abrahamsen B (2020)
Cardiovascular and skeletal safety of zoledronic acid in osteoporosis observational, matched cohort study using Danish and Swedish health registries
Bone, 134, 115296
DOI 10.1016/j.bone.2020.115296, PubMed 32097760

Seljelid B, Varsi C, Solberg Nes L, Stenehjem AE, Bollerslev J, Børøsund E (2020)
Content and system development of a digital patient-provider communication tool to support shared decision making in chronic health care: InvolveMe
BMC Med Inform Decis Mak, 20 (1), 46
DOI 10.1186/s12911-020-1065-8, PubMed 32131808

Seyed Khoei N, Jenab M, Murphy N, Banbury BL, Carreras-Torres R, Viallon V, Kühn T, Bueno-de-Mesquita B, Aleksandrova K, Cross AJ, Weiderpass E, Stepien M, Bulmer A, Tjønneland A, Boutron-Ruault MC, Severi G, Carbonnel F, Katzke V, Boeing H, Bergmann MM, Trichopoulou A, Karakatsani A, Martimianaki G, Palli D, Tagliabue G et al. (2020)
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses
BMC Med, 18 (1), 229
DOI 10.1186/s12916-020-01703-w, PubMed 32878631

Slåtsve KB, Claudi T, Lappegård KT, Jenum AK, Larsen M, Cooper JG, Sandberg S, Julsrud Berg T (2020)
The total prevalence of diagnosed diabetes and the quality of diabetes care for the adult population in Salten, Norway
Scand J Public Health, 1403494820951004
DOI 10.1177/1403494820951004, PubMed 32854596

Størdal K, Bakken IJ, Greve-Isdahl M, Klingenberg C, Helland E, Nystad W, Hjellvik V, Gulseth HL (2020)
SARS-CoV-2 in children and adolescents in Norway: confirmed infection, hospitalisations and underlying conditions
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0457, PubMed 32815353

Svendsen K, Olsen T, Nordstrand Rusvik TC, Ulven SM, Holven KB, Retterstøl K, Telle-Hansen VH (2020)
Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health
Lipids Health Dis, 19 (1), 102
DOI 10.1186/s12944-020-01282-y, PubMed 32438926

Sævik ÅB, Åkerman AK, Methlie P, Quinkler M, Jørgensen AP, Höybye C, Debowska AJ, Nedrebø BG, Dahle AL, Carlsen S, Tomkowicz A, Sollid ST, Nermoen I, Grønning K, Dahlqvist P, Grimnes G, Skov J, Finnes T, Valland SF, Wahlberg J, Holte SE, Simunkova K, Kämpe O, Husebye ES, Bensing S et al. (2020)
Residual Corticosteroid Production in Autoimmune Addison Disease
J Clin Endocrinol Metab, 105 (7)
DOI 10.1210/clinem/dgaa256, PubMed 32392298

Tazmini K, Ranhoff AH (2020)
Electrolyte outpatient clinic at a local hospital - experience from diagnostics, treatment and follow-up
BMC Health Serv Res, 20 (1), 154
DOI 10.1186/s12913-020-5022-0, PubMed 32111205

Tollånes MC, Jenum AK, Berg TJ, Løvaas KF, Cooper JG, Sandberg S (2020)
Availability and analytical quality of hemoglobin A1c point-of-care testing in general practitioners' offices are associated with better glycemic control in type 2 diabetes
Clin Chem Lab Med, 58 (8), 1349-1356
DOI 10.1515/cclm-2020-0026, PubMed 32229656

Ueland T, Estensen ME, Grindheim G, Bollerslev J, Henriksen T, Aukrust P, Aakhus S, Gullestad L, Lekva T (2020)
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902

Ueland T, Roland MCP, Michelsen AE, Godang K, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2020)
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383

Ulven SM, Holven KB (2020)
Metabolomic and gene expression analysis to study the effects of dietary saturated and polyunsaturated fats
Curr Opin Lipidol, 31 (1), 15-19
DOI 10.1097/MOL.0000000000000651, PubMed 31789669

Wang Y, Huang W, O'Neil A, Lan Y, Aune D, Wang W, Yu C, Chen X (2020)
Association between sleep duration and mortality risk among adults with type 2 diabetes: a prospective cohort study
Diabetologia
DOI 10.1007/s00125-020-05214-4, PubMed 32671413

Weider T, Richardson SJ, Morgan NG, Paulsen TH, Dahl-Jørgensen K, Hammerstad SS (2020)
Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis
Thyroid, 30 (3), 432-442
DOI 10.1089/thy.2019.0607, PubMed 31910110

Yammine S, Huybrechts I, Biessy C, Dossus L, Aglago EK, Naudin S, Ferrari P, Weiderpass E, Tjønneland A, Hansen L, Overvad K, Mancini FR, Boutron-Ruault MC, Kvaskoff M, Fortner RT, Kaaks R, Schulze MB, Boeing H, Trichopoulou A, Karakatsani A, La Vecchia C, Benetou V, Masala G, Krogh V, Mattiello A et al. (2020)
Dietary and Circulating Fatty Acids and Ovarian Cancer Risk in the European Prospective Investigation into Cancer and Nutrition
Cancer Epidemiol Biomarkers Prev, 29 (9), 1739-1749
DOI 10.1158/1055-9965.EPI-19-1477, PubMed 32616494

Zheng JS, Sharp SJ, Imamura F, Chowdhury R, Gundersen TE, Steur M, Sluijs I, van der Schouw YT, Agudo A, Aune D, Barricarte A, Boeing H, Chirlaque MD, Dorronsoro M, Freisling H, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Gunter MJ, Kyrø C, Katzke V, Kühn T, Khaw KT, Laouali N et al. (2020)
Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries
BMJ, 370, m2194
DOI 10.1136/bmj.m2194, PubMed 32641421

 
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