Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Section of Endocrinology

53 publications found

Arora GP, Åkerlund M, Brøns C, Moen GH, Wasenius NS, Sommer C, Jenum AK, Almgren P, Thaman RG, Orho-Melander M, Eriksson J, Qvigstad E, Birkeland K, Berntorp K, Vaag AA, Groop L, Prasad RB (2019)
Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus
J Intern Med, 286 (2), 192-206
DOI 10.1111/joim.12903, PubMed 30919529

Blom-Høgestøl IK, Hewitt S, Chahal-Kummen M, Brunborg C, Gulseth HL, Kristinsson JA, Eriksen EF, Mala T (2019)
Bone metabolism, bone mineral density and low-energy fractures 10 years after Roux-en-Y gastric bypass
Bone, 127, 436-445 (in press)
DOI 10.1016/j.bone.2019.07.014, PubMed 31323430

Blom-Høgestøl IK, Mala T, Kristinsson JA, Hauge EM, Brunborg C, Gulseth HL, Eriksen EF (2019)
Changes in Bone Marrow Adipose Tissue One Year After Roux-en-Y Gastric Bypass: A Prospective Cohort Study
J Bone Miner Res (in press)
DOI 10.1002/jbmr.3814, PubMed 31216081

Bogsrud MP, Græsdal A, Johansen D, Langslet G, Hovland A, Arnesen KE, Mundal LJ, Retterstøl K, Wium C, Holven KB (2019)
LDL-cholesterol goal achievement, cardiovascular disease, and attributed risk of Lp(a) in a large cohort of predominantly genetically verified familial hypercholesterolemia
J Clin Lipidol, 13 (2), 279-286
DOI 10.1016/j.jacl.2019.01.010, PubMed 30910667

Bollerslev J, Heck A, Olarescu NC (2019)
MANAGEMENT OF ENDOCRINE DISEASE: Individualized Management of Acromegaly
Eur J Endocrinol, 181 (2), R57-R71
DOI 10.1530/EJE-19-0124, PubMed 31100716

Bollerslev J, Schalin-Jantti C, Rejnmark L, Siggelkow H, Morreau H, Thakker RV, Sitges-Serra A, Cetani F, Marcocci C (2019)
MANAGEMENT OF ENDOCRINE DISEASE: Unmet therapeutic, educational and scientific needs in parathyroid disorders
Eur J Endocrinol (in press)
DOI 10.1530/EJE-19-0316, PubMed 31176307

Borgen TT, Bjørnerem Å, Solberg LB, Andreasen C, Brunborg C, Stenbro MB, Hübschle LM, Froholdt A, Figved W, Apalset EM, Gjertsen JE, Basso T, Lund I, Hansen AK, Stutzer JM, Dahl C, Omsland TK, Nordsletten L, Frihagen F, Eriksen EF (2019)
High prevalence of vertebral fractures and low trabecular bone score in patients with fragility fractures: A cross-sectional sub-study of NoFRACT
Bone, 122, 14-21
DOI 10.1016/j.bone.2019.02.008, PubMed 30743015

Borgen TT, Bjørnerem Å, Solberg LB, Andreasen C, Brunborg C, Stenbro MB, Hübschle LM, Froholdt A, Figved W, Apalset EM, Gjertsen JE, Basso T, Lund I, Hansen AK, Stutzer JM, Omsland TK, Nordsletten L, Frihagen F, Eriksen EF (2019)
Post-fracture Risk Assessment: Target Central Sited Fractures First! A Substudy of NoFRACT
J Bone Miner Res (in press)
DOI 10.1002/jbmr.3827, PubMed 31310352

Borgeraas H, Hjelmesæth J, Birkeland KI, Fatima F, Grimnes JO, Gulseth HL, Halvorsen E, Hertel JK, Hillestad TOW, Johnson LK, Karlsen TI, Kolotkin RL, Kvan NP, Lindberg M, Lorentzen J, Nordstrand N, Sandbu R, Seeberg KA, Seip B, Svanevik M, Valderhaug TG, Hofsø D (2019)
Single-centre, triple-blinded, randomised, 1-year, parallel-group, superiority study to compare the effects of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes and β-cell function in subjects with morbid obesity: a protocol for the Obesity surgery in Tønsberg (Oseberg) study
BMJ Open, 9 (6), e024573
DOI 10.1136/bmjopen-2018-024573, PubMed 31167860

Bornstedt ME, Gjerlaugsen N, Pepaj M, Bredahl MKL, Thorsby PM (2019)
Vitamin D Increases Glucose Stimulated Insulin Secretion from Insulin Producing Beta Cells (INS1E)
Int J Endocrinol Metab, 17 (1), e74255
DOI 10.5812/ijem.74255, PubMed 30881469

Chahal-Kummen M, Blom-Høgestøl IK, Eribe I, Klungsøyr O, Kristinsson J, Mala T (2019)
Abdominal pain and symptoms before and after Roux-en-Y gastric bypass
BJS Open, 3 (3), 317-326
DOI 10.1002/bjs5.50148, PubMed 31183448

Christensen JJ, Bakke SS, Ulven SM, Retterstøl K, Henriksen T, Bollerslev J, Espevik T, Aukrust P, Halvorsen B, Holven KB (2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198

Eilertsen AL, Dahm AEA, Høibraaten E, Lofthus CM, Mowinckel MC, Sandset PM (2019)
Relationship between sex hormone binding globulin and blood coagulation in women on postmenopausal hormone treatment
Blood Coagul Fibrinolysis, 30 (1), 17-23
DOI 10.1097/MBC.0000000000000784, PubMed 30507711

Fedirko V, Jenab M, Méplan C, Jones JS, Zhu W, Schomburg L, Siddiq A, Hybsier S, Overvad K, Tjønneland A, Omichessan H, Perduca V, Boutron-Ruault MC, Kühn T, Katzke V, Aleksandrova K, Trichopoulou A, Karakatsani A, Kotanidou A, Tumino R, Panico S, Masala G, Agnoli C, Naccarati A, Bueno-de-Mesquita B et al. (2019)
Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status
Nutrients, 11 (4)
DOI 10.3390/nu11040935, PubMed 31027226

Feng T, Vegard M, Strand LB, Laugsand LE, Mørkedal B, Aune D, Vatten L, Ellekjaer H, Loennechen JP, Mukamal K, Janszky I (2019)
Metabolically Healthy Obesity and Risk for Atrial Fibrillation: The HUNT Study
Obesity (Silver Spring), 27 (2), 332-338
DOI 10.1002/oby.22377, PubMed 30605242

Gjelsvik B, Tran AT, Berg TJ, Bakke Å, Mdala I, Nøkleby K, Cooper JG, Claudi T, Løvaas KF, Thue G, Sandberg S, Jenum AK (2019)
Exploring the relationship between coronary heart disease and type 2 diabetes: a cross-sectional study of secondary prevention among diabetes patients
BJGP Open, 3 (1), bjgpopen18X101636
DOI 10.3399/bjgpopen18X101636, PubMed 31049416

Gulseth HL, Gjelstad IMF, Tiereny AC, McCarthy D, Lovegrove JA, Defoort C, Blaak EE, Lopez-Miranda J, Dembinska-Kiec A, Risérus U, Roche HM, Drevon CA, Birkeland KI (2019)
Effects of dietary fat on insulin secretion in subjects with the metabolic syndrome
Eur J Endocrinol, 180 (5), 321-328
DOI 10.1530/EJE-19-0022, PubMed 30893645

Gustafsson MK, Romundstad PR, Stafne SN, Helvik AS, Stunes AK, Mørkved S, Salvesen KÅ, Thorsby PM, Mosti MP, Syversen U (2019)
The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial
BMC Pregnancy Childbirth, 19 (1), 76
DOI 10.1186/s12884-019-2220-z, PubMed 30786861

Halden TAS, Kvitne KE, Midtvedt K, Rajakumar L, Robertsen I, Brox J, Bollerslev J, Hartmann A, Åsberg A, Jenssen T (2019)
Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus
Diabetes Care, 42 (6), 1067-1074
DOI 10.2337/dc19-0093, PubMed 30862658

Hansson P, Holven KB, Øyri LKL, Brekke HK, Biong AS, Gjevestad GO, Raza GS, Herzig KH, Thoresen M, Ulven SM (2019)
Meals with Similar Fat Content from Different Dairy Products Induce Different Postprandial Triglyceride Responses in Healthy Adults: A Randomized Controlled Cross-Over Trial
J Nutr, 149 (3), 422-431
DOI 10.1093/jn/nxy291, PubMed 30759235

Hanvold SE, Vinknes KJ, Løken EB, Hjartåker A, Klungsøyr O, Birkeland E, Risstad H, Gulseth HL, Refsum H, Aas AM (2019)
Does Lifestyle Intervention After Gastric Bypass Surgery Prevent Weight Regain? A Randomized Clinical Trial
Obes Surg (in press)
DOI 10.1007/s11695-019-04109-7, PubMed 31363961

Holte KB, Svanteson M, Hanssen KF, Haig Y, Solheim S, Berg TJ (2019)
Undiagnosed coronary artery disease in long-term type 1 diabetes. The Dialong study
J Diabetes Complications, 33 (5), 383-389
DOI 10.1016/j.jdiacomp.2019.01.006, PubMed 30846232

Joergensen D, Tazmini K, Jacobsen D (2019)
Acute Dysnatremias - a dangerous and overlooked clinical problem
Scand J Trauma Resusc Emerg Med, 27 (1), 58
DOI 10.1186/s13049-019-0633-3, PubMed 31138251

Jorde R, Stunes AK, Kubiak J, Joakimsen R, Grimnes G, Thorsby PM, Syversen U (2019)
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
Bone, 124, 7-13
DOI 10.1016/j.bone.2019.04.002, PubMed 30959189

Kelly CB, Yu JY, Jenkins AJ, Nankervis AJ, Hanssen KF, Garg SK, Scardo JA, Basu A, Hammad SM, Aston CE, Lyons TJ (2019)
Haptoglobin phenotype modulates lipoprotein-associated risk for preeclampsia in women with Type 1 diabetes
J Clin Endocrinol Metab (in press)
DOI 10.1210/jc.2019-00723, PubMed 31219590

Kinnunen TI, Richardsen KR, Sletner L, Torgersen L, Sommer C, Waage CW, Mdala I, Jenum AK (2019)
Ethnic differences in body mass index trajectories from 18 years to postpartum in a population-based cohort of pregnant women in Norway
BMJ Open, 9 (2), e022640
DOI 10.1136/bmjopen-2018-022640, PubMed 30798304

Kobeissi E, Hibino M, Pan H, Aune D (2019)
Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies
Eur J Epidemiol, 34 (6), 547-555
DOI 10.1007/s10654-019-00510-9, PubMed 30903463

Kristiansen MS, Stabursvik J, O'Leary EC, Pedersen M, Asprusten TT, Leegaard T, Osnes LT, Tjade T, Skovlund E, Godang K, Wyller VBB (2019)
Clinical symptoms and markers of disease mechanisms in adolescent chronic fatigue following Epstein-Barr virus infection: An exploratory cross-sectional study
Brain Behav Immun, 80, 551-563
DOI 10.1016/j.bbi.2019.04.040, PubMed 31039432

Lee S, Kolset SO, Birkeland KI, Drevon CA, Reine TM (2019)
Acute exercise increases syndecan-1 and -4 serum concentrations
Glycoconj J, 36 (2), 113-125
DOI 10.1007/s10719-019-09869-z, PubMed 30949875

Lee S, Norheim F, Langleite TM, Gulseth HL, Birkeland KI, Drevon CA (2019)
Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic, overweight men and sedentary normoglycaemic men of healthy weight
Diabetologia, 62 (6), 1048-1064
DOI 10.1007/s00125-019-4866-5, PubMed 31011777

Lewis JR, Eggermont CJ, Schousboe JT, Lim WH, Wong G, Khoo B, Sim M, Yu M, Ueland T, Bollerslev J, Hodgson JM, Zhu K, Wilson KE, Kiel DP, Prince RL (2019)
Association between abdominal aortic calcification, bone mineral density and fracture in older women
J Bone Miner Res (in press)
DOI 10.1002/jbmr.3830, PubMed 31310354

Lillejordet E, Rashid HU, Evang JA, Taraldsrud E, Gunnarsson R (2019)
A woman in her forties with influenza symptoms and swollen arm
Tidsskr Nor Laegeforen, 139 (1)
DOI 10.4045/tidsskr.17.0170, PubMed 30644687

Moen GH, Hemani G, Warrington NM, Evans DM (2019)
Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies
Behav Genet, 49 (3), 327-339
DOI 10.1007/s10519-018-9944-9, PubMed 30600410

Myhrstad MCW, de Mello VD, Dahlman I, Kolehmainen M, Paananen J, Rundblad A, Carlberg C, Olstad OK, Pihlajamäki J, Holven KB, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Storm MU, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Risérus U, Thorsdottir I, Poutanen KS, Savolainen MJ, Schwab U, Arner P et al. (2019)
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study
Mol Nutr Food Res, 63 (13), 1801405
DOI 10.1002/mnfr.201801405, PubMed 30964598

Neuenschwander M, Ballon A, Weber KS, Norat T, Aune D, Schwingshackl L, Schlesinger S (2019)
Role of diet in type 2 diabetes incidence: umbrella review of meta-analyses of prospective observational studies
BMJ, 366, l2368
DOI 10.1136/bmj.l2368, PubMed 31270064

Nygaard S, Christensen AH, Rolid K, Nytrøen K, Gullestad L, Fiane A, Thaulow E, Døhlen G, Godang K, Saul JP, Wyller VBB (2019)
Autonomic cardiovascular control changes in recent heart transplant recipients lead to physiological limitations in response to orthostatic challenge and isometric exercise
Eur J Appl Physiol (in press)
DOI 10.1007/s00421-019-04207-5, PubMed 31407088

Ofstad AP, Sommer C, Birkeland KI, Bjørgaas MR, Gran JM, Gulseth HL, Johansen OE (2019)
Comparison of the associations between non-traditional and traditional indices of adiposity and cardiovascular mortality: an observational study of one million person-years of follow-up
Int J Obes (Lond), 43 (5), 1082-1092
DOI 10.1038/s41366-019-0353-9, PubMed 30926954

Olarescu NC, Perez-Rivas LG, Gatto F, Cuny T, Tichomirowa MA, Tamagno G, Gahete MD, EYRC (ENEA Young Researcher Committee) (2019)
Aggressive and Malignant Prolactinomas
Neuroendocrinology, 109 (1), 57-69
DOI 10.1159/000497205, PubMed 30677777

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765

Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, Liou AP, Woods RM, Parry SA, Jeppesen PB, Kolnes AJ, Harding HP, Ron D, Vidal-Puig A, Reimann F, Gribble FM et al. (2019)
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
Cell Metab, 29 (3), 707-718.e8
DOI 10.1016/j.cmet.2018.12.016, PubMed 30639358

Pedersen M, Asprusten TT, Godang K, Leegaard TM, Osnes LT, Skovlund E, Tjade T, Øie MG, Wyller VBB (2019)
Lifestyle factors during acute Epstein-Barr virus infection in adolescents predict physical activity six months later
Acta Paediatr, 108 (8), 1521-1526
DOI 10.1111/apa.14728, PubMed 30685875

Rundblad A, Larsen SV, Myhrstad MC, Ottestad I, Thoresen M, Holven KB, Ulven SM (2019)
Differences in peripheral blood mononuclear cell gene expression and triglyceride composition in lipoprotein subclasses in plasma triglyceride responders and non-responders to omega-3 supplementation
Genes Nutr, 14, 10
DOI 10.1186/s12263-019-0633-y, PubMed 31057673

Scharff M, Wiepjes C, Klaver M, Schreiner T, Tsjoen GR, den Heijer M (2019)
Change in grip strength in trans people and its association with lean body mass and bone density
Endocr Connect, 8 (7), 1020-1028
DOI 10.1530/EC-19-0196, PubMed 31247588

Stomby A, Salami A, Dahlqvist P, Evang JA, Ryberg M, Bollerslev J, Olsson T, Johannsson G, Ragnarsson O (2019)
Elevated resting-state connectivity in the medial temporal lobe and the prefrontal cortex among patients with Cushing's syndrome in remission
Eur J Endocrinol, 180 (5), 329-338
DOI 10.1530/EJE-19-0028, PubMed 30939453

Svanteson M, Holte KB, Haig Y, Kløw NE, Berg TJ (2019)
Coronary plaque characteristics and epicardial fat tissue in long term survivors of type 1 diabetes identified by coronary computed tomography angiography
Cardiovasc Diabetol, 18 (1), 58
DOI 10.1186/s12933-019-0861-x, PubMed 31054573

Svendsen K, Jacobs DR, Røyseth IT, Garstad KW, Byfuglien MG, Granlund L, Mørch-Reiersen LT, Telle-Hansen VH, Retterstøl K (2019)
Community pharmacies offer a potential high-yield and convenient arena for total cholesterol and CVD risk screening
Eur J Public Health, 29 (1), 17-23
DOI 10.1093/eurpub/cky190, PubMed 30239673

Tapia G, Mårild K, Dahl SR, Lund-Blix NA, Viken MK, Lie BA, Njølstad PR, Joner G, Skrivarhaug T, Cohen AS, Størdal K, Stene LC (2019)
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241

Tazmini K, Nymo SH, Louch WE, Ranhoff AH, Øie E (2019)
Electrolyte imbalances in an unselected population in an emergency department: A retrospective cohort study
PLoS One, 14 (4), e0215673
DOI 10.1371/journal.pone.0215673, PubMed 31022222

Ueland T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2019)
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982

Ueland T, Stilgren L, Bollerslev J (2019)
Bone Matrix Levels of Dickkopf and Sclerostin are Positively Correlated with Bone Mass and Strength in Postmenopausal Osteoporosis
Int J Mol Sci, 20 (12)
DOI 10.3390/ijms20122896, PubMed 31197079

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Qiao Z, Moen GH, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N et al. (2019)
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Nat Genet, 51 (5), 804-814
DOI 10.1038/s41588-019-0403-1, PubMed 31043758

Zebaze R, Osima M, Bui M, Lukic M, Wang X, Ghasem-Zadeh A, Eriksen EF, Vais A, Shore-Lorenti C, Ebeling PR, Seeman E, Bjørnerem Å (2019)
Adding Marrow Adiposity and Cortical Porosity to Femoral Neck Areal Bone Mineral Density Improves the Discrimination of Women With Nonvertebral Fractures From Controls
J Bone Miner Res, 34 (8), 1451-1460
DOI 10.1002/jbmr.3721, PubMed 30883870

Aasdahl L, Iversen VM, Skovlund E, Aune D, Fimland MS (2019)
What should be the preferred exercise modality for overweight and obese individuals? Protocol for a systematic review and network meta-analysis
Syst Rev, 8 (1), 41
DOI 10.1186/s13643-019-0964-1, PubMed 30717790

 
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