Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2016 from OUS - Section of Endocrinology

60 publications found

Astor MC, Løvås K, Debowska A, Eriksen EF, Evang JA, Fossum C, Fougner KJ, Holte SE, Lima K, Moe RB, Myhre AG, Kemp EH, Nedrebø BG, Svartberg J, Husebye ES (2016)
Epidemiology and Health-Related Quality of Life in Hypoparathyroidism in Norway
J Clin Endocrinol Metab, 101 (8), 3045-53
DOI 10.1210/jc.2016-1477, PubMed 27186861

Aune D, Keum N, Giovannucci E, Fadnes LT, Boffetta P, Greenwood DC, Tonstad S, Vatten LJ, Riboli E, Norat T (2016)
Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies
BMJ, 353, i2716
DOI 10.1136/bmj.i2716, PubMed 27301975

Aune D, Sen A, Henriksen T, Saugstad OD, Tonstad S (2016)
Physical activity and the risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis of epidemiological studies
Eur J Epidemiol, 31 (10), 967-997
DOI 10.1007/s10654-016-0176-0, PubMed 27485519

Aune D, Sen A, Prasad M, Norat T, Janszky I, Tonstad S, Romundstad P, Vatten LJ (2016)
BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants
BMJ, 353, i2156
DOI 10.1136/bmj.i2156, PubMed 27146380

Berents TL, Lødrup Carlsen KC, Mowinckel P, Sandvik L, Skjerven HO, Rolfsjord LB, Kvenshagen B, Hunderi JO, Bradley M, Lieden A, Carlsen KH, Thorsby PM, Gjersvik P (2016)
Vitamin D levels and atopic eczema in infancy and early childhood in Norway: a cohort study
Br J Dermatol, 175 (1), 95-101
DOI 10.1111/bjd.14537, PubMed 26972308

Bogsrud MP, Ulven SM, Holven KB (2016)
Does intrauterine exposure to hypercholesterolemia adversely affect familial hypercholesterolemia phenotype?
Curr Opin Lipidol, 27 (4), 382-7
DOI 10.1097/MOL.0000000000000299, PubMed 27070077

Bruserud Ø, Oftedal BE, Landegren N, Erichsen MM, Bratland E, Lima K, Jørgensen AP, Myhre AG, Svartberg J, Fougner KJ, Bakke Å, Nedrebø BG, Mella B, Breivik L, Viken MK, Knappskog PM, Marthinussen MC, Løvås K, Kämpe O, Wolff AB, Husebye ES (2016)
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1
J Clin Endocrinol Metab, 101 (8), 2975-83
DOI 10.1210/jc.2016-1821, PubMed 27253668

Bye A, Wesseltoft-Rao N, Iversen PO, Skjegstad G, Holven KB, Ulven S, Hjermstad MJ (2016)
Alterations in inflammatory biomarkers and energy intake in cancer cachexia: a prospective study in patients with inoperable pancreatic cancer
Med Oncol, 33 (6), 54
DOI 10.1007/s12032-016-0768-2, PubMed 27119533

Casar-Borota O, Øystese KA, Sundström M, Melchior L, Popovic V (2016)
A high-throughput analysis of the IDH1(R132H) protein expression in pituitary adenomas
Pituitary, 19 (4), 407-14
DOI 10.1007/s11102-016-0720-7, PubMed 27097804

Christensen JJ, Retterstøl K, Godang K, Roland MC, Qvigstad E, Bollerslev J, Ueland T, Henriksen T, Holven KB (2016)
LDL cholesterol in early pregnancy and offspring cardiovascular disease risk factors
J Clin Lipidol, 10 (6), 1369-1378.e7
DOI 10.1016/j.jacl.2016.08.016, PubMed 27919354

Dekker MJ, Wierckx K, Van Caenegem E, Klaver M, Kreukels BP, Elaut E, Fisher AD, van Trotsenburg MA, Schreiner T, den Heijer M, T'Sjoen G (2016)
A European Network for the Investigation of Gender Incongruence: Endocrine Part
J Sex Med, 13 (6), 994-9
DOI 10.1016/j.jsxm.2016.03.371, PubMed 27162190

Duarte Sosa D, Fink Eriksen E (2016)
Women with previous stress fractures show reduced bone material strength
Acta Orthop, 87 (6), 626-631
DOI 10.1080/17453674.2016.1198883, PubMed 27321443

Dusanov S, Brandal K, Heggen E, Tonstad S (2016)
Associations of Circulating PYY3-36 Concentrations with Metabolic Syndrome in Extremely Obese Subjects
Metab Syndr Relat Disord, 14 (8), 410-415
DOI 10.1089/met.2016.0031, PubMed 27513679

Dusanov S, Heggen E, Tonstad S (2016)
Characteristics of Metabolic Syndrome in Morbidly Obese Subjects
Metab Syndr Relat Disord, 14 (10), 500-506
DOI 10.1089/met.2016.0062, PubMed 27513810

Eggemoen ÅR, Falk RS, Knutsen KV, Lagerløv P, Sletner L, Birkeland KI, Jenum AK (2016)
Vitamin D deficiency and supplementation in pregnancy in a multiethnic population-based cohort
BMC Pregnancy Childbirth, 16, 7
DOI 10.1186/s12884-016-0796-0, PubMed 26785795

Ford PA, Jaceldo-Siegl K, Lee JW, Tonstad S (2016)
Trans fatty acid intake is related to emotional affect in the Adventist Health Study-2
Nutr Res, 36 (6), 509-17
DOI 10.1016/j.nutres.2016.01.005, PubMed 27188896

Frigstad SO, Høivik M, Jahnsen J, Dahl SR, Cvancarova M, Grimstad T, Berset IP, Huppertz-Hauss G, Hovde Ø, Torp R, Bernklev T, Moum B, Jelsness-Jørgensen LP (2016)
Vitamin D deficiency in inflammatory bowel disease: prevalence and predictors in a Norwegian outpatient population
Scand J Gastroenterol, 52 (1), 100-106
DOI 10.1080/00365521.2016.1233577, PubMed 27603182

Godang K, Olarescu NC, Bollerslev J, Heck A (2016)
Treatment of acromegaly increases BMD but reduces trabecular bone score: a longitudinal study
Eur J Endocrinol, 175 (2), 155-64
DOI 10.1530/EJE-16-0340, PubMed 27220351

Halvorsen B, Santilli F, Scholz H, Sahraoui A, Gulseth HL, Wium C, Lattanzio S, Formoso G, Di Fulvio P, Otterdal K, Retterstøl K, Holven KB, Gregersen I, Stavik B, Bjerkeli V, Michelsen AE, Ueland T, Liani R, Davi G, Aukrust P (2016)
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
DOI 10.1007/s00125-016-4036-y, PubMed 27421726

Haugen G, Bollerslev J, Henriksen T (2016)
Human umbilical and fetal cerebral blood flow velocity waveforms following maternal glucose loading: a cross-sectional observational study
Acta Obstet Gynecol Scand, 95 (6), 683-9
DOI 10.1111/aogs.12913, PubMed 27099205

Hofsø D, Bollerslev J, Sandbu R, Jørgensen A, Godang K, Hjelmesæth J, Ueland T (2016)
Bone resorption following weight loss surgery is associated with treatment procedure and changes in secreted Wnt antagonists
Endocrine, 53 (1), 313-21
DOI 10.1007/s12020-016-0903-z, PubMed 26956843

Holme I, Retterstøl K, Norum KR, Hjermann I (2016)
Lifelong benefits on myocardial infarction mortality: 40-year follow-up of the randomized Oslo diet and antismoking study
J Intern Med, 280 (2), 221-7
DOI 10.1111/joim.12485, PubMed 26924204

Jørgenrud B, Stene LC, Tapia G, Bøås H, Pepaj M, Berg JP, Thorsby PM, Orešič M, Hyötyläinen T, Rønningen KS (2016)
Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study
Pediatr Diabetes, 18 (2), 111-119
DOI 10.1111/pedi.12360, PubMed 26791677

Jørgensen HS, Eide IA, Hartmann A, Åsberg A, Christensen JH, Schmidt EB, Godang K, Bollerslev J, Svensson M (2016)
Plasma n-3 Polyunsaturated Fatty Acids and Bone Mineral Density in Renal Transplant Recipients
J Ren Nutr, 26 (3), 196-203
DOI 10.1053/j.jrn.2015.11.007, PubMed 26776249

Kahleova H, Tonstad S, Rosmus J, Fisar P, Mari A, Hill M, Pelikanova T (2016)
The effect of a vegetarian versus conventional hypocaloric diet on serum concentrations of persistent organic pollutants in patients with type 2 diabetes
Nutr Metab Cardiovasc Dis, 26 (5), 430-8
DOI 10.1016/j.numecd.2016.01.008, PubMed 27107842

Kinnunen TI, Waage CW, Sommer C, Sletner L, Raitanen J, Jenum AK (2016)
Ethnic Differences in Gestational Weight Gain: A Population-Based Cohort Study in Norway
Matern Child Health J, 20 (7), 1485-96
DOI 10.1007/s10995-016-1947-7, PubMed 26979613

Krog AH, Sahba M, Pettersen EM, Sandven I, Thorsby PM, Jørgensen JJ, Sundhagen JO, Kazmi SS (2016)
Comparison of the acute-phase response after laparoscopic versus open aortobifemoral bypass surgery: a substudy of a randomized controlled trial
Vasc Health Risk Manag, 12, 371-378
DOI 10.2147/VHRM.S110600, PubMed 27713633

Langleite TM, Jensen J, Norheim F, Gulseth HL, Tangen DS, Kolnes KJ, Heck A, Storås T, Grøthe G, Dahl MA, Kielland A, Holen T, Noreng HJ, Stadheim HK, Bjørnerud A, Johansen EI, Nellemann B, Birkeland KI, Drevon CA (2016)
Insulin sensitivity, body composition and adipose depots following 12 w combined endurance and strength training in dysglycemic and normoglycemic sedentary men
Arch Physiol Biochem, 122 (4), 167-179
DOI 10.1080/13813455.2016.1202985, PubMed 27477619

Langslet G, Breazna A, Drogari E (2016)
A 3-year study of atorvastatin in children and adolescents with heterozygous familial hypercholesterolemia
J Clin Lipidol, 10 (5), 1153-1162.e3
DOI 10.1016/j.jacl.2016.05.010, PubMed 27678432

Leder L, Kolehmainen M, Narverud I, Dahlman I, Myhrstad MC, de Mello VD, Paananen J, Carlberg C, Schwab U, Herzig KH, Cloetens L, Storm MU, Hukkanen J, Savolainen MJ, Rosqvist F, Hermansen K, Dragsted LO, Gunnarsdottir I, Thorsdottir I, Risérus U, Åkesson B, Thoresen M, Arner P, Poutanen KS, Uusitupa M et al. (2016)
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
Genes Nutr, 11, 3
DOI 10.1186/s12263-016-0521-4, PubMed 27482295

Lee S, Norheim F, Langleite TM, Noreng HJ, Storås TH, Afman LA, Frost G, Bell JD, Thomas EL, Kolnes KJ, Tangen DS, Stadheim HK, Gilfillan GD, Gulseth HL, Birkeland KI, Jensen J, Drevon CA, Holen T, NutriTech Consortium (2016)
Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging
Physiol Rep, 4 (21)
DOI 10.14814/phy2.13019, PubMed 27821717

Lekva T, Lyle R, Roland MC, Friis C, Bianchi DW, Jaffe IZ, Norwitz ER, Bollerslev J, Henriksen T, Ueland T (2016)
Gene expression in term placentas is regulated more by spinal or epidural anesthesia than by late-onset preeclampsia or gestational diabetes mellitus
Sci Rep, 6, 29715
DOI 10.1038/srep29715, PubMed 27405415

Lekva T, Michelsen AE, Bollerslev J, Norwitz ER, Aukrust P, Henriksen T, Ueland T (2016)
Low circulating pentraxin 3 levels in pregnancy is associated with gestational diabetes and increased apoB/apoA ratio: a 5-year follow-up study
Cardiovasc Diabetol, 15, 23
DOI 10.1186/s12933-016-0345-1, PubMed 26842615

Losa M, Bollerslev J (2016)
Pros and cons in endocrine practice: pre-surgical treatment with somatostatin analogues in acromegaly
Endocrine, 52 (3), 451-7
DOI 10.1007/s12020-015-0853-x, PubMed 26785848

Myhrstad MC, Ottestad I, Günther CC, Ryeng E, Holden M, Nilsson A, Brønner KW, Kohler A, Borge GI, Holven KB, Ulven SM (2016)
The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects
Genes Nutr, 11, 16
DOI 10.1186/s12263-016-0530-6, PubMed 27551317

Narverud I, Myhrstad MC, Herzig KH, Karhu T, Dahl TB, Halvorsen B, Ulven SM, Holven KB (2016)
Lack of Effects of a Single High-Fat Meal Enriched with Vegetable n-3 or a Combination of Vegetable and Marine n-3 Fatty Acids on Intestinal Peptide Release and Adipokines in Healthy Female Subjects
Front Nutr, 3, 38
DOI 10.3389/fnut.2016.00038, PubMed 27630989

Nerhus M, Berg AO, Kvitland LR, Dieset I, Hope S, Dahl SR, Weibell MA, Romm KL, Faerden A, Andreassen OA, Melle I (2016)
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553

Normann KR, Øystese KAB, Berg JP, Lekva T, Berg-Johnsen J, Bollerslev J, Olarescu NC (2016)
Selection and validation of reliable reference genes for RT-qPCR analysis in a large cohort of pituitary adenomas
Mol Cell Endocrinol, 437, 183-189
DOI 10.1016/j.mce.2016.08.030, PubMed 27561203

Olarescu NC, Bollerslev J (2016)
The Impact of Adipose Tissue on Insulin Resistance in Acromegaly
Trends Endocrinol Metab, 27 (4), 226-237
DOI 10.1016/j.tem.2016.02.005, PubMed 26948712

Olsen HG, Knutsen TM, Lewandowska-Sabat AM, Grove H, Nome T, Svendsen M, Arnyasi M, Sodeland M, Sundsaasen KK, Dahl SR, Heringstad B, Hansen HH, Olsaker I, Kent MP, Lien S (2016)
Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gene in clinical mastitis and milk production
Genet Sel Evol, 48 (1), 79
DOI 10.1186/s12711-016-0257-2, PubMed 27760518

Ottestad I, Nordvi B, Vogt G, Holck M, Halvorsen B, Brønner KW, Retterstøl K, Holven KB, Nilsson A, Ulven SM (2016)
Bioavailability of n-3 fatty acids from n-3-enriched foods and fish oil with different oxidative quality in healthy human subjects: a randomised single-meal cross-over study
J Nutr Sci, 5, e43
DOI 10.1017/jns.2016.34, PubMed 28620470

Paschalis EP, Gamsjaeger S, Hassler N, Fahrleitner-Pammer A, Dobnig H, Stepan JJ, Pavo I, Eriksen EF, Klaushofer K (2016)
Vitamin D and calcium supplementation for three years in postmenopausal osteoporosis significantly alters bone mineral and organic matrix quality
Bone, 95, 41-46
DOI 10.1016/j.bone.2016.11.002, PubMed 27826025

Pepaj M, Bredahl MK, Gjerlaugsen N, Thorsby PM (2016)
Proteomic analysis of the INS-1E secretome identify novel vitamin D-regulated proteins
Diabetes Metab Res Rev, 32 (6), 514-21
DOI 10.1002/dmrr.2777, PubMed 26788927

Qvigstad E, Gulseth HL, Risstad H, le Roux CW, Berg TJ, Mala T, Kristinsson JA (2016)
A novel technique of Roux-en-Y gastric bypass reversal for postprandial hyperinsulinemic hypoglycaemia: A case report
Int J Surg Case Rep, 21, 91-4
DOI 10.1016/j.ijscr.2016.02.033, PubMed 26957187

Risstad H, Svanevik M, Kristinsson JA, Hjelmesæth J, Aasheim ET, Hofsø D, Søvik TT, Karlsen TI, Fagerland MW, Sandbu R, Mala T (2016)
Standard vs Distal Roux-en-Y Gastric Bypass in Patients With Body Mass Index 50 to 60: A Double-blind, Randomized Clinical Trial
JAMA Surg, 151 (12), 1146-1155
DOI 10.1001/jamasurg.2016.2798, PubMed 27626242

Shabestari M, Vik J, Reseland JE, Eriksen EF (2016)
Bone marrow lesions in hip osteoarthritis are characterized by increased bone turnover and enhanced angiogenesis
Osteoarthritis Cartilage, 24 (10), 1745-1752
DOI 10.1016/j.joca.2016.05.009, PubMed 27233775

Simonsen CS, Celius EG, Brunborg C, Tallaksen C, Eriksen EF, Holmøy T, Moen SM (2016)
Bone mineral density in patients with multiple sclerosis, hereditary ataxia or hereditary spastic paraplegia after at least 10 years of disease - a case control study
BMC Neurol, 16 (1), 252
DOI 10.1186/s12883-016-0771-4, PubMed 27919248

Sollid ST, Hutchinson MY, Berg V, Fuskevåg OM, Figenschau Y, Thorsby PM, Jorde R (2016)
Effects of vitamin D binding protein phenotypes and vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D
Eur J Endocrinol, 174 (4), 445-52
DOI 10.1530/EJE-15-1089, PubMed 26733479

Sommer C, Gulseth HL, Jenum AK, Sletner L, Thorsby PM, Birkeland KI (2016)
Soluble Leptin Receptor and Risk of Gestational Diabetes in a Multiethnic Population: A Prospective Cohort Study
J Clin Endocrinol Metab, 101 (11), 4070-4075
DOI 10.1210/jc.2016-2583, PubMed 27537771

Størset E, von Düring ME, Godang K, Bergan S, Midtvedt K, Åsberg A (2016)
Prediction of Fat-Free Mass in Kidney Transplant Recipients
Ther Drug Monit, 38 (4), 439-46
DOI 10.1097/FTD.0000000000000305, PubMed 27019101

Sørensen IM, Joner G, Jenum PA, Eskild A, Brunborg C, Torjesen PA, Stene LC (2016)
Vitamin D-binding protein and 25-hydroxyvitamin D during pregnancy in mothers whose children later developed type 1 diabetes
Diabetes Metab Res Rev, 32 (8), 883-890
DOI 10.1002/dmrr.2812, PubMed 27103201

Sørensen M, Arneberg F, Line TM, Berg TJ (2016)
Cost of diabetes in Norway 2011
Diabetes Res Clin Pract, 122, 124-132
DOI 10.1016/j.diabres.2016.10.012, PubMed 27837695

Ulven SM, Leder L, Elind E, Ottestad I, Christensen JJ, Telle-Hansen VH, Skjetne AJ, Raael E, Sheikh NA, Holck M, Torvik K, Lamglait A, Thyholt K, Byfuglien MG, Granlund L, Andersen LF, Holven KB (2016)
Exchanging a few commercial, regularly consumed food items with improved fat quality reduces total cholesterol and LDL-cholesterol: a double-blind, randomised controlled trial
Br J Nutr, 116 (8), 1383-1393
DOI 10.1017/S0007114516003445, PubMed 27737722

von Düring ME, Jenssen T, Bollerslev J, Åsberg A, Godang K, Hartmann A (2016)
Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation
Clin Transplant, 31 (1)
DOI 10.1111/ctr.12869, PubMed 27859633

Wyller VB, Vitelli V, Sulheim D, Fagermoen E, Winger A, Godang K, Bollerslev J (2016)
Altered neuroendocrine control and association to clinical symptoms in adolescent chronic fatigue syndrome: a cross-sectional study
J Transl Med, 14 (1), 121
DOI 10.1186/s12967-016-0873-1, PubMed 27149955

Waage C, Jenum AK, Mdala I, Berg JP, Richardsen K, Birkeland K (2016)
Associations between gestational diabetes mellitus and elevated HbA1c early postpartum in a multi-ethnic population
Prim Care Diabetes, 11 (2), 132-139
DOI 10.1016/j.pcd.2016.09.007, PubMed 27771271

Waage CW, Mdala I, Jenum AK, Michelsen TM, Birkeland KI, Sletner L (2016)
Ethnic differences in blood pressure from early pregnancy to postpartum: a Norwegian cohort study
J Hypertens, 34 (6), 1151-9
DOI 10.1097/HJH.0000000000000918, PubMed 27088633

Øystese KA, Evang JA, Bollerslev J (2016)
Non-functioning pituitary adenomas: growth and aggressiveness
Endocrine, 53 (1), 28-34
DOI 10.1007/s12020-016-0940-7, PubMed 27066792

Aakre I, Strand TA, Bjøro T, Norheim I, Barikmo I, Ares S, Alcorta MD, Henjum S (2016)
Thyroid Function among Breastfed Children with Chronically Excessive Iodine Intakes
Nutrients, 8 (7)
DOI 10.3390/nu8070398, PubMed 27367720

Aass C, Norheim I, Eriksen EF, Børnick EC, Thorsby PM, Pepaj M (2016)
Comparative proteomic analysis of tear fluid in Graves' disease with and without orbitopathy
Clin Endocrinol (Oxf), 85 (5), 805-812
DOI 10.1111/cen.13122, PubMed 27256639

 
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