Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

Click here to see hierarchical division and subunit overview

Summary of publications:

Publications (original articles or review articles) published in 2017 from OUS - Department of Pharmacology

25 publications found

Ahamed M, Vermeulen K, Schnekenburger M, Moltzau LR, Levy FO, Marton J, Froeyen M, Olberg DE, Diederich M, Bormans G (2017)
Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers
Lett. Drug Des. Discov., 14 (7), 787-797

Baftiu A, Feet SA, Larsson PG, Burns ML, Henning O, Sætre E, Molden E, Granas AG, Johannessen SI, Landmark CJ (2017)
Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015
Epilepsy Res, 139, 35-42
DOI 10.1016/j.eplepsyres.2017.11.001, PubMed 29175562

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2017)
Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
Epilepsia, 58 (2), 181-221
DOI 10.1111/epi.13634, PubMed 28111749

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ (2017)
Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII)
Epilepsy Res, 130, 27-36
DOI 10.1016/j.eplepsyres.2017.01.004, PubMed 28113141

Bremer S, Vethe NT, Skauby M, Kasbo M, Johansson ED, Midtvedt K, Bergan S (2017)
NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation
Br J Clin Pharmacol, 83 (11), 2494-2502
DOI 10.1111/bcp.13367, PubMed 28686294

Egeland EJ, Robertsen I, Hermann M, Midtvedt K, Størset E, Gustavsen MT, Reisæter AV, Klaasen R, Bergan S, Holdaas H, Hartmann A, Åsberg A (2017)
High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation
Transplantation, 101 (8), e273-e279
DOI 10.1097/TP.0000000000001796, PubMed 28452920

Føreid S, Gadeholt G (2017)
Beta-hydroxybutyrate and pyroglutamate can be included in a rapid GC-MS screening method for differential diagnosis of metabolic acidosis
Scand J Clin Lab Invest, 77 (2), 149-152
DOI 10.1080/00365513.2016.1278261, PubMed 28150506

Havig SM, Høiseth G, Strand MC, Karinen RA, Brochmann GW, Strand DH, Bachs L, Vindenes V (2017)
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Forensic Sci Int, 276, 12-17
DOI 10.1016/j.forsciint.2017.04.006, PubMed 28463706

Hjelmeland K, Gustavsen I, Øiestad EL, Øiestad ÅML, Høiseth G, Mørland J (2017)
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci Int, 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217

Jendresen C, Daws MR, Nilsson LNG (2017)
An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells
J Pharmacol Toxicol Methods, 90, 67-75
DOI 10.1016/j.vascn.2017.11.004, PubMed 29203451

Jendresen C, Årskog V, Daws MR, Nilsson LN (2017)
The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
J Neuroinflammation, 14 (1), 59
DOI 10.1186/s12974-017-0835-4, PubMed 28320424

Johannessen Landmark C, Burns ML, Baftiu A, Farmen AH, Lossius MI, Johannessen SI, Tomson T (2017)
Pharmacokinetic variability of valproate in women of childbearing age
Epilepsia, 58 (10), e142-e146
DOI 10.1111/epi.13872, PubMed 28833045

Krogh N, Rzeppa S, Dyreborg A, Dehnes Y, Hemmersbach P, Backer V, Hostrup M (2017)
Terbutaline Accumulates in Blood and Urine after Daily Therapeutic Inhalation
Med Sci Sports Exerc, 49 (6), 1236-1243
DOI 10.1249/MSS.0000000000001199, PubMed 28072631

Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur J Pharmacol, 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992

Midtvedt K, Bergan S, Reisæter AV, Vikse BE, Åsberg A (2017)
Exposure to Mycophenolate and Fatherhood
Transplantation, 101 (7), e214-e217
DOI 10.1097/TP.0000000000001747, PubMed 28346297

Pisani LR, Nikanorova M, Landmark CJ, Johannessen SI, Pisani F (2017)
Specific Patient Features Affect Antiepileptic Drug Therapy Decisions: Focus on Gender, Age, and Psychiatric Comorbidities
Curr Pharm Des, 23 (37), 5639-5648
DOI 10.2174/1381612823666170926103631, PubMed 28950817

Pitarch-Motellón J, Roig-Navarro AF, Sancho JV, Ibáñez M, Fabregat-Cabello N, Pozo OJ, Ventura R, García Alonso JI, Rodríguez-González P, González Gago A, Ereño Artabe A, Van Eenoo P, Deventer K, Dehnes Y, Rzeppa S (2017)
Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry
J Chromatogr A, 1508, 73-80
DOI 10.1016/j.chroma.2017.05.072, PubMed 28601363

Salvador CL, Hartmann A, Åsberg A, Bergan S, Rowe AD, Mørkrid L (2017)
Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population
Transplant Direct, 3 (12), e332
DOI 10.1097/TXD.0000000000000742, PubMed 29536033

Skauby RH, Bjerre A, Sæves I, Vethe NT, Bremer S, Svarstad A, Bergan S (2017)
Prednisolone and Prednisone Pharmacokinetics in Pediatric Renal Transplant Recipients-A Prospective Study
Ther Drug Monit, 39 (5), 472-482
DOI 10.1097/FTD.0000000000000439, PubMed 28749817

Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T (2017)
The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans
Can J Physiol Pharmacol, 95 (9), 1009-1018
DOI 10.1139/cjpp-2016-0635, PubMed 28467859

Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2017)
The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation
Br J Clin Pharmacol, 83 (7), 1457-1465
DOI 10.1111/bcp.13248, PubMed 28146606

Svendsen T, Brodtkorb E, Baftiu A, Burns ML, Johannessen SI, Johannessen Landmark C (2017)
Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability
Neurochem Res, 42 (7), 2077-2083
DOI 10.1007/s11064-017-2234-8, PubMed 28349359

Torp HA, Gustavsen I, Romundstad L (2017)
A botanical anesthesia
Tidsskr. Nor. Laegeforen., 137 (23-24), 1924-1928

Westergren T, Narum S, Klemp M (2017)
Characterization of gastrointestinal adverse effects reported in clinical studies of corticosteroid therapy
J Clin Epidemiol, 94, 19-26
DOI 10.1016/j.jclinepi.2017.10.018, PubMed 29113937

Ødegård J, Sondresen JE, Aasrum M, Tveteraas IH, Guren TK, Christoffersen T, Thoresen GH (2017)
Differential effects of epidermal growth factor (EGF) receptor ligands on receptor binding, downstream signalling pathways and DNA synthesis in hepatocytes
Growth Factors, 35 (6), 239-248
DOI 10.1080/08977194.2018.1453506, PubMed 29582692

 
Page visits: 70894