Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Division of Cardiovascular and Pulmonary Diseases

33 publications found

Arora S, Ofstad AP, Ulimoen GR, Birkeland KI, Endresen K, Gullestad L, Johansen OE (2019)
Asymptomatic coronary artery disease in a Norwegian cohort with type 2 diabetes: a prospective angiographic study with intravascular ultrasound evaluation
Cardiovasc Diabetol, 18 (1), 26
DOI 10.1186/s12933-019-0832-2, PubMed 30851727

Boe E, Smiseth OA, Storsten P, Andersen OS, Aalen J, Eriksen M, Krogh MR, Kongsgaard E, Remme EW, Skulstad H (2019)
Left ventricular end-systolic volume is a more sensitive marker of acute response to cardiac resynchronization therapy than contractility indices: insights from an experimental study
Europace, 21 (2), 347-355
DOI 10.1093/europace/euy221, PubMed 30418572

Bothe W, Kvitting JE, Rausch MK, Timek TA, Swanson JC, Liang DH, Walther M, Kuhl E, Ingels NB, Miller DC (2019)
Do annuloplasty rings designed to treat ischemic/functional mitral regurgitation alter left-ventricular dimensions in the acutely ischemic ovine heart?
J Thorac Cardiovasc Surg (in press)
DOI 10.1016/j.jtcvs.2018.12.077, PubMed 30803776

Braun OÖ, Nilsson J, Gustafsson F, Dellgren G, Fiane AE, Lemström K, Hubbert L, Hellgren L, Lund LH (2019)
Continuous-flow LVADs in the Nordic countries: complications and mortality and its predictors
Scand Cardiovasc J, 1-7 (in press)
DOI 10.1080/14017431.2019.1583365, PubMed 30776923

Brynildsen J, Petäjä L, Myhre PL, Lyngbakken MN, Nygård S, Stridsberg M, Christensen G, Ottesen AH, Pettilä V, Omland T, Røsjø H (2019)
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med (in press)
DOI 10.1097/CCM.0000000000003670, PubMed 30730440

Cardim N, Dalen H, Voigt JU, Ionescu A, Price S, Neskovic AN, Edvardsen T, Galderisi M, Sicari R, Donal E, Stefanidis A, Delgado V, Zamorano J, Popescu BA (2019)
The use of handheld ultrasound devices: a position statement of the European Association of Cardiovascular Imaging (2018 update)
Eur Heart J Cardiovasc Imaging, 20 (3), 245-252
DOI 10.1093/ehjci/jey145, PubMed 30351358

Castrini AI, Lie ØH, Leren IS, Estensen ME, Stokke MK, Klæboe LG, Edvardsen T, Haugaa KH (2019)
Number of pregnancies and subsequent phenotype in a cross-sectional cohort of women with arrhythmogenic cardiomyopathy
Eur Heart J Cardiovasc Imaging, 20 (2), 192-198
DOI 10.1093/ehjci/jey061, PubMed 29659777

Dahle G, Helle-Valle T, Beitnes JO, Espinoza A, Halvorsen PS, Rein KA (2019)
Single-centre first experience with transapical transcatheter mitral valve replacement with an apical tether: factors influencing screening outcomes
Interact Cardiovasc Thorac Surg (in press)
DOI 10.1093/icvts/ivy343, PubMed 30602024

de Boer RA, De Keulenaer G, Bauersachs J, Brutsaert D, Cleland JG, Diez J, Du XJ, Ford P, Heinzel FR, Lipson KE, McDonagh T, Lopez-Andres N, Lunde IG, Lyon AR, Pollesello P, Prasad SK, Tocchetti CG, Mayr M, Sluijter JPG, Thum T, Tschöpe C, Zannad F, Zimmermann WH, Ruschitzka F, Filippatos G et al. (2019)
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
Eur J Heart Fail, 21 (3), 272-285
DOI 10.1002/ejhf.1406, PubMed 30714667

Diab SG, Døhlen G, Seem E, Möller T (2019)
Fontan-sirkulasjon ved univentrikulære hjertefeil
Tidsskr Nor Laegeforen, 139 (5)
DOI 10.4045/tidsskr.18.0451, PubMed 30872828

Fox K, Achenbach S, Bax J, Cosyns B, Delgado V, Dweck MR, Edvardsen T, Flachskampf F, Habib G, Lancellotti P, Muraru D, Neglia D, Pontone G, Schwammenthal E, Sechtem U, Westwood M, Popescu BA (2019)
Multimodality imaging in cardiology: a statement on behalf of the Task Force on Multimodality Imaging of the European Association of Cardiovascular Imaging
Eur Heart J, 40 (6), 553-558
DOI 10.1093/eurheartj/ehy669, PubMed 30380037

Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279

Haugaa KH, Lie ØH (2019)
Cardiac amyloidosis: can imaging shed light on mechanisms and prognosis?
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jez009, PubMed 30726891

Jusufovic M, Skagen K, Krohg-Sørensen K, Skjelland M (2019)
Current medical and surgical stroke prevention therapies for patients with carotid artery stenosis
Curr Neurovasc Res (in press)
DOI 10.2174/1567202616666190131162811, PubMed 30706783

Klaeboe LG, Brekke PH, Lie ØH, Aaberge L, Haugaa KH, Edvardsen T (2019)
Classical mechanical dyssynchrony is rare in transcatheter aortic valve implantation-induced left bundle branch block
Eur Heart J Cardiovasc Imaging, 20 (3), 271-278
DOI 10.1093/ehjci/jey127, PubMed 30247533

Krogh MR, Halvorsen PS, Elle OJ, Bergsland J, Remme EW (2019)
Dynamic gravity compensation does not increase detection of myocardial ischemia in combined accelerometer and gyro sensor measurements
Sci Rep, 9 (1), 2671
DOI 10.1038/s41598-018-35630-x, PubMed 30804438

Lipsett DB, Frisk M, Aronsen JM, Nordén ES, Buonarati OR, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE (2019)
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J Physiol (in press)
DOI 10.1113/JP277273, PubMed 30707448

Lorén CE, Dahl CP, Do L, Almaas VM, Geiran OR, Mörner S, Hellman U (2019)
Low Molecular Mass Myocardial Hyaluronan in Human Hypertrophic Cardiomyopathy
Cells, 8 (2)
DOI 10.3390/cells8020097, PubMed 30699940

Louch WE (2019)
Channel surfing: new insights into plasticity of excitation-contraction coupling
J Physiol (in press)
DOI 10.1113/JP277783, PubMed 30854650

Nytrøen K, Rolid K, Andreassen AK, Yardley M, Gude E, Dahle DO, Bjørkelund E, Authen AR, Grov I, Wigh JP, Dall CH, Gustafsson F, Karason K, Gullestad L (2019)
Effect of High-Intensity Interval Training in De Novo Heart Transplant Recipients in Scandinavia: 1-Year Follow-Up of the HITTS Randomized, Controlled Study
Circulation (in press)
DOI 10.1161/CIRCULATIONAHA.118.036747, PubMed 30773030

Peersen K, Otterstad JE, Sverre E, Perk J, Gullestad L, Moum T, Dammen T, Munkhaugen J (2019)
Medical and Psychosocial Factors Associated With Low Physical Activity and Increasing Exercise Level After a Coronary Event
J Cardiopulm Rehabil Prev (in press)
DOI 10.1097/HCR.0000000000000399, PubMed 30720643

Platonov PG, Haugaa KH, Bundgaard H, Svensson A, Gilljam T, Hansen J, Madsen T, Holst AG, Carlson J, Lie ØH, Kvistholm Jensen M, Edvardsen T, Jensen HK, Svendsen JH (2019)
Primary Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy
Am J Cardiol, 123 (7), 1156-1162
DOI 10.1016/j.amjcard.2018.12.049, PubMed 30678832

Schalit I, Espinoza A, Pettersen FJ, Snartland S, Ringdal ML, Hoel TN, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2019)
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J (in press)
DOI 10.1097/MAT.0000000000000954, PubMed 30688692

Sheard TMD, Hurley ME, Colyer J, White E, Norman R, Pervolaraki E, Narayanasamy KK, Hou Y, Kirton HM, Yang Z, Hunter L, Shim JU, Clowsley AH, Smith AJ, Baddeley D, Soeller C, Colman MA, Jayasinghe I (2019)
Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy
ACS Nano, 13 (2), 2143-2157
DOI 10.1021/acsnano.8b08742, PubMed 30715853

Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM (2019)
Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
Am J Physiol Heart Circ Physiol (in press)
DOI 10.1152/ajpheart.00637.2018, PubMed 30657726

Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA (2019)
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
J Plast Surg Hand Surg, 53 (2), 119-124
DOI 10.1080/2000656X.2018.1562459, PubMed 30654667

Solberg OG, Stavem K, Ragnarsson A, Beitnes JO, Skårdal R, Seljeflot I, Ueland T, Aukrust P, Gullestad L, Aaberge L (2019)
Index of microvascular resistance to assess the effect of rosuvastatin on microvascular function in women with chest pain and no obstructive coronary artery disease: A double-blind randomized study
Catheter Cardiovasc Interv (in press)
DOI 10.1002/ccd.28157, PubMed 30790446

Stokke IM, Li ZB, Cicala S, Okin PM, Kjeldsen SE, Devereux RB, Wachtell K (2019)
Association of left bundle branch block with new onset abnormal wall motion in treated hypertensive patients with left ventricle hypertrophy: the LIFE Echo Sub-study
Blood Press, 28 (2), 84-92
DOI 10.1080/08037051.2019.1569463, PubMed 30698038

Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE (2019)
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
Sci Transl Med, 11 (476)
DOI 10.1126/scitranslmed.aat1199, PubMed 30674652

Van Bulck L, Luyckx K, Goossens E, Apers S, Kovacs AH, Thomet C, Budts W, Sluman MA, Eriksen K, Dellborg M, Berghammer M, Johansson B, Caruana M, Soufi A, Callus E, Moons P (2019)
Patient-reported outcomes of adults with congenital heart disease from eight European countries: scrutinising the association with healthcare system performance
Eur J Cardiovasc Nurs, 1474515119834484 (in press)
DOI 10.1177/1474515119834484, PubMed 30808198

Öjlert ÅK, Halvorsen AR, Nebdal D, Lund-Iversen M, Solberg S, Brustugun OT, Lingjaerde OC, Helland Å (2019)
The immune microenvironment in non-small cell lung cancer is predictive of prognosis after surgery
Mol Oncol (in press)
DOI 10.1002/1878-0261.12475, PubMed 30854794

Aalen JM, Remme EW, Larsen CK, Andersen OS, Krogh M, Duchenne J, Hopp E, Ross S, Beela AS, Kongsgaard E, Bergsland J, Odland HH, Skulstad H, Opdahl A, Voigt JU, Smiseth OA (2019)
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2018.11.030, PubMed 30772230

Aamodt IT, Lycholip E, Celutkiene J, Strömberg A, Atar D, Falk RS, von Lueder T, Hellesø R, Jaarsma T, Lie I (2019)
Health Care Professionals' Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey
J Med Internet Res, 21 (2), e10362
DOI 10.2196/10362, PubMed 30724744

 
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