Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Division of Clinical Neuroscience

55 publications found

Alves DE, Nilsen W, Fure SCR, Enehaug H, Howe EI, Løvstad M, Fink L, Andelic N, Spjelkavik Ø (2020)
What characterises work and workplaces that retain their employees following acquired brain injury? Systematic review
Occup Environ Med, 77 (2), 122-130
DOI 10.1136/oemed-2019-106102, PubMed 31907293

Andelic N, Forslund MV, Perrin PB, Sigurdardottir S, Lu J, Howe EI, Sveen U, Rasmussen MS, Søberg HL, Røe C (2020)
Long-term follow-up of use of therapy services for patients with moderate-to-severe traumatic brain injury
J Rehabil Med, 52 (3), jrm00034
DOI 10.2340/16501977-2662, PubMed 32179933

Arzimanoglou A, Brandl U, Cross JH, Gil-Nagel A, Lagae L, Landmark CJ, Specchio N, Nabbout R, Thiele EA, Gubbay O, The Cannabinoids International Experts Panel, Collaborators (2020)
Epilepsy and cannabidiol: a guide to treatment
Epileptic Disord, 22 (1), 1-14
DOI 10.1684/epd.2020.1141, PubMed 32096470

Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J et al. (2020)
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia
Brain, 143 (1), 234-248
DOI 10.1093/brain/awz350, PubMed 31755958

Borgen IMH, Løvstad M, Andelic N, Hauger S, Sigurdardottir S, Søberg HL, Sveen U, Forslund MV, Kleffelgård I, Lindstad MØ, Winter L, Røe C (2020)
Traumatic brain injury-needs and treatment options in the chronic phase: Study protocol for a randomized controlled community-based intervention
Trials, 21 (1), 294
DOI 10.1186/s13063-020-4195-5, PubMed 32216840

Børte S, Zwart JA, Skogholt AH, Gabrielsen ME, Thomas LF, Fritsche LG, Surakka I, Nielsen JB, Zhou W, Wolford BN, Vigeland MD, Hagen K, Kristoffersen ES, Nyholt DR, Chasman DI, Brumpton BM, Willer CJ, Winsvold BS (2020)
Mitochondrial genome-wide association study of migraine - the HUNT Study
Cephalalgia, 0333102420906835
DOI 10.1177/0333102420906835, PubMed 32056457

Eikeland R, Ljøstad U, Helgeland G, Sand G, Flemmen HØ, Bø MH, Nordaa L, Owe JF, Mygland Å, Lorentzen ÅR (2020)
Patient-reported outcome after treatment for definite Lyme neuroborreliosis
Brain Behav, e01595 (in press)
DOI 10.1002/brb3.1595, PubMed 32153118

Fazio P, Fitzer-Attas CJ, Mrzljak L, Bronzova J, Nag S, Warner JH, Landwehrmeyer B, Al-Tawil N, Halldin C, Forsberg A, Ware J, Dilda V, Wood A, Sampaio C, Varrone A, Svenningsson P, Paucar M, Sundblom J, Nyholm D, Widner H, Heiberg A, Frich J, Nielsen J, Hjermind L, Roos R et al. (2020)
PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression
Mov. Disord.

Fjellaksel R, Moldes-Anaya A, Vasskog T, Oteiza A, Martin-Armas M, Hjelstuen OK, Hansen JH, Riss PJ, Sundset R (2020)
Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH-receptor ligands for brain SPECT imaging
J Labelled Comp Radiopharm, 63 (2), 72-84
DOI 10.1002/jlcr.3820, PubMed 31813158

Fraser AN, Bjørdal J, Wagle TM, Karlberg AC, Lien OA, Eilertsen L, Mader K, Apold H, Larsen LB, Madsen JE, Fjalestad T (2020)
Reverse Shoulder Arthroplasty Is Superior to Plate Fixation at 2 Years for Displaced Proximal Humeral Fractures in the Elderly: A Multicenter Randomized Controlled Trial
J Bone Joint Surg Am, 102 (6), 477-485
DOI 10.2106/JBJS.19.01071, PubMed 31977825

González A, Nome CG, Bendiksen BA, Sjaastad I, Zhang L, Aleksandersen M, Taubøll E, Aurlien D, Heuser K (2020)
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Epilepsy Res, 161, 106300
DOI 10.1016/j.eplepsyres.2020.106300, PubMed 32126491

Hagen K, Stovner LJ, Zwart JA (2020)
Time trends of major headache diagnoses and predictive factors. Data from three Nord-Trøndelag health surveys
J Headache Pain, 21 (1), 24
DOI 10.1186/s10194-020-01095-5, PubMed 32160857

Hammar Å, Semkovska M, Borgen IMH, Myklebost S, Ronold EH, Sveen T, Ueland T, Porter R, Johnson SL (2020)
A pilot study of cognitive remediation in remitted major depressive disorder patients
Appl Neuropsychol Adult
DOI 10.1080/23279095.2020.1726919, PubMed 32088993

Hamre C, Fure B, Helbostad JL, Wyller TB, Ihle-Hansen H, Vlachos G, Ursin M, Tangen GG (2020)
Balance and Gait After First Minor Ischemic Stroke in People 70 Years of Age or Younger: A Prospective Observational Cohort Study
Phys Ther (in press)
DOI 10.1093/ptj/pzaa010, PubMed 31944247

Hazen J, Vistnes M, Barca ML, Eldholm RS, Persson K, Brækhus A, Saltvedt I, Selbæk G, Engedal K, Knapskog AB (2020)
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
Alzheimer Dis Assoc Disord, 34 (1), 47-53
DOI 10.1097/WAD.0000000000000342, PubMed 31414991

Hott A, Brox JI, Pripp AH, Juel NG, Liavaag S (2020)
Patellofemoral pain: One year results of a randomized trial comparing hip exercise, knee exercise, or free activity
Scand J Med Sci Sports, 30 (4), 741-753
DOI 10.1111/sms.13613, PubMed 31846113

Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE (2020)
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
Mol Oncol (in press)
DOI 10.1002/1878-0261.12668, PubMed 32171051

Johannessen Landmark C, Johannessen SI, Patsalos PN (2020)
Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects
Expert Opin Drug Metab Toxicol, 16 (3), 227-238
DOI 10.1080/17425255.2020.1724956, PubMed 32054370

Kolnes AJ, Øystese KA, Dahlberg D, Berg-Johnsen J, Niehusmann P, Pahnke J, Bollerslev J, Jørgensen AP (2020)
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma
Acta Neurochir (Wien), 162 (4), 845-852
DOI 10.1007/s00701-019-04068-z, PubMed 31907611

Kramer V, Brooks AF, Haeger A, Kuljis RO, Rafique W, Koeppe RA, Raffel DM, Frey KA, Amaral H, Scott PJH, Riss PJ (2020)
Evaluation of [18F]-N-Methyl lansoprazole as a Tau PET Imaging Agent in First-in-Human Studies
ACS Chem Neurosci, 11 (3), 427-435
DOI 10.1021/acschemneuro.9b00639, PubMed 31898886

Kristoffersen PM, Vetti N, Storheim K, Bråten LC, Rolfsen MP, Assmus J, Espeland A (2020)
Short tau inversion recovery MRI of Modic changes: a reliability study
Acta Radiol Open, 9 (1), 2058460120902402
DOI 10.1177/2058460120902402, PubMed 32064122

Krohn L, Wu RYJ, Heilbron K, Ruskey JA, Laurent SB, Blauwendraat C, Alam A, Arnulf I, Hu MTM, Dauvilliers Y, Högl B, Toft M, Bjørnarå KA, Stefani A, Holzknecht E, Monaca CC, Abril B, Plazzi G, Antelmi E, Ferini-Strambi L, Young P, Heidbreder A, Cochen De Cock V, Mollenhauer B, Sixel-Döring F et al. (2020)
Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies
Ann Neurol, 87 (4), 584-598
DOI 10.1002/ana.25687, PubMed 31976583

Kubach J, Muhlebner-Fahrngruber A, Soylemezoglu F, Miyata H, Niehusmann P, Honavar M, Rogerio F, Kim SH, Aronica E, Garbelli R, Vilz S, Popp A, Walcher S, Neuner C, Scholz M, Kuerten S, Schropp V, Roeder S, Eichhorn P, Eckstein M, Brehmer A, Kobow K, Coras R, Blumcke I, Jabari S (2020)
Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations
Epilepsia, 61 (3), 421-432
DOI 10.1111/epi.16447, PubMed 32080846

Landmark CJ, Brandl U (2020)
Pharmacology and drug interactions of cannabinoids
Epileptic Disord, 22 (S1), 16-22
DOI 10.1684/epd.2019.1123, PubMed 31941642

Lao YE, Molden E, Kringen MK, Annexstad EJ, Saeverud HA, Jacobsen D, Hovda KE (2020)
Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes
Basic Clin Pharmacol Toxicol
DOI 10.1111/bcpt.13389, PubMed 31977139

Larsson C, Groote I, Vardal J, Kleppestø M, Odland A, Brandal P, Due-Tønnessen P, Holme SS, Hope TR, Meling TR, Fosse E, Emblem KE, Bjørnerud A (2020)
Prediction of survival and progression in glioblastoma patients using temporal perfusion changes during radiochemotherapy
Magn Reson Imaging, 68, 106-112 (in press)
DOI 10.1016/j.mri.2020.01.012, PubMed 32004711

Lashkarivand A, Sorteberg W, Rosseland LA, Sorteberg A (2020)
Survival and outcome in patients with aneurysmal subarachnoid hemorrhage in Glasgow coma score 3-5
Acta Neurochir (Wien), 162 (3), 533-544
DOI 10.1007/s00701-019-04190-y, PubMed 31980948

Lemée JM, Corniola MV, Meling TR (2020)
Benefits of re-do surgery for recurrent intracranial meningiomas
Sci Rep, 10 (1), 303
DOI 10.1038/s41598-019-57254-5, PubMed 31941981

Llorens A, Funderud I, Blenkmann AO, Lubell J, Foldal M, Leske S, Huster R, Meling TR, Knight RT, Solbakk AK, Endestad T (2020)
Preservation of Interference Effects in Working Memory After Orbitofrontal Damage
Front Hum Neurosci, 13, 445
DOI 10.3389/fnhum.2019.00445, PubMed 31998097

Lossius K, de Saint Martin A, Myren-Svelstad S, Bjørnvold M, Minken G, Seegmuller C, Valenti Hirsch MP, Chelly J, Steinlein O, Picard F, Brodtkorb E (2020)
Remarkable effect of transdermal nicotine in children with CHRNA4-related autosomal dominant sleep-related hypermotor epilepsy
Epilepsy Behav, 105, 106944 (in press)
DOI 10.1016/j.yebeh.2020.106944, PubMed 32097883

Luger S, Jæger HS, Dixon J, Bohmann FO, Schaefer J, Richieri SP, Larsen K, Hov MR, Bache KG, Foerch C, BE FAST III Study Group (2020)
Diagnostic Accuracy of Glial Fibrillary Acidic Protein and Ubiquitin Carboxy-Terminal Hydrolase-L1 Serum Concentrations for Differentiating Acute Intracerebral Hemorrhage from Ischemic Stroke
Neurocrit Care
DOI 10.1007/s12028-020-00931-5, PubMed 32096121

Malhotra K, Goyal N, Katsanos AH, Filippatou A, Mistry EA, Khatri P, Anadani M, Spiotta AM, Sandset EC, Sarraj A, Magoufis G, Krogias C, Tönges L, Safouris A, Elijovich L, Goyal M, Arthur A, Alexandrov AV, Tsivgoulis G (2020)
Association of Blood Pressure With Outcomes in Acute Stroke Thrombectomy
Hypertension, 75 (3), 730-739
DOI 10.1161/HYPERTENSIONAHA.119.14230, PubMed 31928111

Meisingset I, Vasseljen O, Vøllestad NK, Robinson HS, Woodhouse A, Engebretsen KB, Glette M, Øverås CK, Nordstoga AL, Evensen KAI, Skarpsno ES (2020)
Novel approach towards musculoskeletal phenotypes
Eur J Pain
DOI 10.1002/ejp.1541, PubMed 32040225

Najafi J, Brembu T, Vie AK, Viste R, Winge P, Somssich IE, Bones AM (2020)
PAMP-INDUCED SECRETED PEPTIDE 3 modulates immunity in Arabidopsis
J Exp Bot, 71 (3), 850-864
DOI 10.1093/jxb/erz482, PubMed 31665431

Nakken KO, Henning O (2020)
Bør epilepsipasienter og pårørende informeres om risikoen for plutselig død?
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0708, PubMed 31948206

Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation (in press)
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258

Nome T, Herrman H, Lehtimäki K, Egge A, Konglund A, Ramm-Pettersen J, Taubøll E, Dietrichs E (2020)
Direct visual targeting versus preset coordinates for ANT-DBS in epilepsy
Acta Neurol Scand
DOI 10.1111/ane.13233, PubMed 32078161

Ringstad G, Eide PK (2020)
Glymphatic MRI
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0651, PubMed 31948208

Ringstad G, Eide PK (2020)
Cerebrospinal fluid tracer efflux to parasagittal dura in humans
Nat Commun, 11 (1), 354
DOI 10.1038/s41467-019-14195-x, PubMed 31953399

Sigurdardottir S, Andelic N, Røe C, Schanke AK (2020)
Trajectory of 10-Year Neurocognitive Functioning After Moderate-Severe Traumatic Brain Injury: Early Associations and Clinical Application
J Int Neuropsychol Soc, 1-14 (in press)
DOI 10.1017/S1355617720000193, PubMed 32098637

Simonsen CS, Flemmen HØ, Lauritzen T, Berg-Hansen P, Moen SM, Celius EG (2020)
The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis
Mult Scler J Exp Transl Clin, 6 (1), 2055217319901291
DOI 10.1177/2055217319901291, PubMed 32030196

Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA (2020)
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043

Stensvold E, Stadskleiv K, Myklebust TÅ, Wesenberg F, Helseth E, Bechensteen AG, Brandal P (2020)
Unmet rehabilitation needs in 86% of Norwegian paediatric embryonal brain tumour survivors
Acta Paediatr
DOI 10.1111/apa.15188, PubMed 31977119

Svendsen T, Brodtkorb E, Baftiu A, Lossius MI, Nakken KO, Johannessen SI, Johannessen Landmark C (2020)
Clinical experience combined with therapeutic drug monitoring of lacosamide
Acta Neurol Scand, 141 (4), 279-286
DOI 10.1111/ane.13206, PubMed 31853958

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20 (in press)
DOI 10.1159/000504529, PubMed 32028277

Taso M, Sommernes JH, Kolstad F, Sundseth J, Bjorland S, Pripp AH, Zwart JA, Brox JI (2020)
A randomised controlled trial comparing the effectiveness of surgical and nonsurgical treatment for cervical radiculopathy
BMC Musculoskelet Disord, 21 (1), 171
DOI 10.1186/s12891-020-3188-6, PubMed 32178655

Thompson PM, Jahanshad N, Ching CRK, Salminen LE, Thomopoulos SI, Bright J, Baune BT, Bertolín S, Bralten J, Bruin WB, Bülow R, Chen J, Chye Y, Dannlowski U, de Kovel CGF, Donohoe G, Eyler LT, Faraone SV, Favre P, Filippi CA, Frodl T, Garijo D, Gil Y, Grabe HJ, Grasby KL et al. (2020)
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361

van Walsem MR, Howe EI, Perrin PB, Sigurdardottir S, Røe C, Sveen U, Lu J, Forslund MV, Andelic N (2020)
Trajectories of self-reported competency up to 10 years following moderate-to-severe traumatic brain injury
Brain Inj, 34 (3), 335-342
DOI 10.1080/02699052.2019.1704061, PubMed 31928233

Voldsbekk I, Maximov II, Zak N, Roelfs D, Geier O, Due-Tønnessen P, Elvsåshagen T, Strømstad M, Bjørnerud A, Groote I (2020)
Evidence for wakefulness-related changes to extracellular space in human brain white matter from diffusion-weighted MRI
Neuroimage, 212, 116682 (in press)
DOI 10.1016/j.neuroimage.2020.116682, PubMed 32114147

Zaidan S, Nakken KO, Lillestolen KM, Alvestad S, Lossius MI (2020)
Assisted reproductive technologies among women with epilepsy
Tidsskr. Nor. Laegeforen., 140 (1), 51-53

Zaidan S, Nakken KO, Lillestølen KM, Alvestad S, Lossius MI (2020)
Assistert befruktning blant kvinner med epilepsi
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0253, PubMed 31948216

Zaidan S, Nakken KO, Lillestølen KM, Alvestad S, Lossius MI (2020)
Rettelse: Assistert befruktning blant kvinner med epilepsi
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.20.0063, PubMed 32105046

Zamani M, Skagen K, Scott H, Russell D, Skjelland M (2020)
Advanced ultrasound methods in assessment of carotid plaque instability: a prospective multimodal study
BMC Neurol, 20 (1), 39
DOI 10.1186/s12883-020-1620-z, PubMed 31996153

Aasdahl L, Marchand GH, Gismervik SØ, Myhre K, Fimland MS, Røe C (2020)
The Fear Avoidance Beliefs Questionnaire (FABQ) Does it Really Measure Fear Beliefs?
Spine (Phila Pa 1976), 45 (2), 134-140
DOI 10.1097/BRS.0000000000003188, PubMed 31415468

Aasdahl L, Marchand GH, Gismervik SØ, Myhre K, Fimland MS, Røe C (2020)
Response to the Letter to the Editor from Monticone et al
Spine (Phila Pa 1976) (in press)
DOI 10.1097/BRS.0000000000003417, PubMed 32068646

 
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