Neuroendocrine tumors (NET) Publications
Publications 2026
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Extended D3 Mesenterectomy in Small Bowel Cancer Treatment: Feasibility and Importance for Staging. First Results of a Prospective Clinical Trial
World J Surg (in press)
DOI 10.1002/wjs.70550, PubMed 42682155 -
Small Bowel Cancer: Implications of Preoperative Work-Up on Surgical Strategy
World J Surg (in press)
DOI 10.1002/wjs.70547, PubMed 42693594
Publications 2025
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The relationship between dose, concentration and toxicity of everolimus in the treatment of neuroendocrine tumors: A prospective observational study
J Neuroendocrinol, 38 (1), e70107
DOI 10.1111/jne.70107, PubMed 41204799 -
Association rule mining of clinical and biomarker data in neuroendocrine tumors: A prospective study on disease progression
J Neuroendocrinol, 37 (10), e70069
DOI 10.1111/jne.70069, PubMed 40812788
Publications 2024
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Diarrhoea of unknown cause: medical treatment in a stepwise manner<b>Management of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment</b>
Scand J Gastroenterol, 59 (5), 543-546
DOI 10.1080/00365521.2024.2313061, PubMed 38343268 -
Longitudinal Fecal Microbiota Profiles in A Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue
Pathogens, 13 (11)
DOI 10.3390/pathogens13110953, PubMed 39599506 -
Hypoalbuminemia, but not derived neutrophil to lymphocyte ratio (dNLR), predicts overall survival in neuroendocrine tumours undergoing peptide receptor radionuclide therapy: A retrospective, cohort study of 557 patients
J Neuroendocrinol, 37 (3), e13379
DOI 10.1111/jne.13379, PubMed 38477040
Publications 2023
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Improved health-related quality of life during peptide receptor radionuclide therapy in patients with neuroendocrine tumours
J Neuroendocrinol, 35 (10), e13342
DOI 10.1111/jne.13342, PubMed 37807573 -
Hemicolectomy versus appendectomy for patients with appendiceal neuroendocrine tumours 1-2 cm in size: a retrospective, Europe-wide, pooled cohort study
Lancet Oncol, 24 (2), 187-194
DOI 10.1016/S1470-2045(22)00750-1, PubMed 36640790 -
Treatment efficacy in a metastatic small intestinal neuroendocrine tumour grade 2 cohort
Endocr Relat Cancer, 30 (3)
DOI 10.1530/ERC-22-0316, PubMed 36629395 -
Incidence and prevalence of neuroendocrine neoplasms in Norway 1993-2021
J Neuroendocrinol, 35 (4), e13264
DOI 10.1111/jne.13264, PubMed 36988112
Publications 2022
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Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal
Ann Surg, 277 (5), e1063-e1071
DOI 10.1097/SLA.0000000000005663, PubMed 35975918 -
Lifestyle predictors for inconsistent participation to fecal based colorectal cancer screening
BMC Cancer, 22 (1), 172
DOI 10.1186/s12885-022-09287-9, PubMed 35168592 -
Letter to the Editor: Overall Survival in Patients with Stage IV Pan-NET Eligible for Liver Transplantation
World J Surg, 47 (4), 1083
DOI 10.1007/s00268-022-06873-7, PubMed 36566298 -
Plasma protein biomarkers for the detection of pancreatic neuroendocrine tumors and differentiation from small intestinal neuroendocrine tumors
J Neuroendocrinol, 34 (7), e13176
DOI 10.1111/jne.13176, PubMed 35829662
Publications 2021
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Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
Acta Oncol, 60 (7), 931-941
DOI 10.1080/0284186X.2021.1921262, PubMed 33999752
Publications 2020
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A Plasma Protein Biomarker Strategy for Detection of Small Intestinal Neuroendocrine Tumors
Neuroendocrinology, 111 (9), 840-849
DOI 10.1159/000510483, PubMed 32721955 -
Association between lifestyle and site-specific advanced colorectal lesions in screening with faecal immunochemical test and sigmoidoscopy
Dig Liver Dis, 53 (3), 353-359
DOI 10.1016/j.dld.2020.11.021, PubMed 33309513 -
Patient reported symptoms, coping and quality of life during somatostatin analogue treatment for metastatic small- intestinal neuroendocrine tumours
Health Qual Life Outcomes, 18 (1), 188
DOI 10.1186/s12955-020-01452-7, PubMed 32546236 -
Achieving objective response in treatment of non-resectable neuroendocrine tumors does not predict longer time to progression compared to achieving stable disease
BMC Cancer, 20 (1), 466
DOI 10.1186/s12885-020-06963-6, PubMed 32448245
Publications 2019
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Prospective Study of Chromogranin A as a Predictor of Progression in Patients with Pancreatic, Small-Intestinal, and Unknown Primary Neuroendocrine Tumors
Neuroendocrinology, 110 (3-4), 217-224
DOI 10.1159/000503833, PubMed 31578011 -
Pharmacogenomic analyses of sunitinib in patients with pancreatic neuroendocrine tumors
Future Oncol, 15 (17), 1997-2007
DOI 10.2217/fon-2018-0934, PubMed 31084373 -
Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease - associations with disease phenotype, treatment, and outcome
Clin Exp Gastroenterol, 12, 37-49
DOI 10.2147/CEG.S186235, PubMed 30774408 -
Favorable Outcome in Patients with Pheochromocytoma and Paraganglioma Treated with 177Lu-DOTATATE
Cancers (Basel), 11 (7)
DOI 10.3390/cancers11070909, PubMed 31261748
Publications 2018
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The RECIST criteria compared to conventional response evaluation after peptide receptor radionuclide therapy in patients with neuroendocrine neoplasms
Ann Nucl Med, 33 (3), 147-152
DOI 10.1007/s12149-018-1316-2, PubMed 30406360 -
Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours
Neuroendocrinology, 107 (3), 237-245
DOI 10.1159/000491999, PubMed 29991024
Publications 2017
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Survival in neuroendocrine neoplasms; A report from a large Norwegian population-based study
Int J Cancer, 142 (6), 1139-1147
DOI 10.1002/ijc.31137, PubMed 29082524 -
Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation
Neuroradiology, 59 (2), 105-126
DOI 10.1007/s00234-017-1804-4, PubMed 28255902
Publications 2016
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Serological markers in diagnosis of pediatric inflammatory bowel disease and as predictors for early tumor necrosis factor blocker therapy
Scand J Gastroenterol, 52 (4), 414-419
DOI 10.1080/00365521.2016.1259653, PubMed 27887202
Publications 2015
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Trends in Incidence of Neuroendocrine Neoplasms in Norway: A Report of 16,075 Cases from 1993 through 2010
Neuroendocrinology, 104 (1), 1-10
DOI 10.1159/000442207, PubMed 26562558 -
The biliary epithelium presents antigens to and activates natural killer T cells
Hepatology, 62 (4), 1249-59
DOI 10.1002/hep.27840, PubMed 25855031 -
Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences
J Invest Dermatol, 135 (7), 1771-1780
DOI 10.1038/jid.2015.85, PubMed 25739051 -
Myocardial Function by Two-Dimensional Speckle Tracking Echocardiography and Activin A May Predict Mortality in Patients with Carcinoid Intestinal Disease
Cardiology, 132 (2), 81-90
DOI 10.1159/000431076, PubMed 26111973
Publications 2014
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Survival and prognostic factors in well-differentiated pancreatic neuroendocrine tumors
Scand J Gastroenterol, 49 (6), 734-41
DOI 10.3109/00365521.2014.903432, PubMed 24679166 -
European panel on the appropriateness of gastrointestinal endoscopy II guidelines help in selecting and prioritizing patients referred to colonoscopy--a quality control study
Scand J Gastroenterol, 49 (4), 492-500
DOI 10.3109/00365521.2014.886715, PubMed 24597781 -
Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
Acta Oncol, 53 (10), 1284-97
DOI 10.3109/0284186X.2014.941999, PubMed 25140861 -
Early anti-TNF treatment in pediatric Crohn's disease. Predictors of clinical outcome in a population-based cohort of newly diagnosed patients
Scand J Gastroenterol, 49 (12), 1425-31
DOI 10.3109/00365521.2014.966316, PubMed 25310799 -
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
DOI 10.1002/ijc.29039, PubMed 24948044
Publications 2013
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Comparison of 24-h and overnight samples of urinary 5-hydroxyindoleacetic acid in patients with intestinal neuroendocrine tumors
Endocr Connect, 2 (1), 50-4
DOI 10.1530/EC-12-0077, PubMed 23781318 -
Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial
United European Gastroenterol J, 1 (3), 162-8
DOI 10.1177/2050640613483290, PubMed 24917955
Publications 2012
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A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
Clin Transl Gastroenterol, 3 (12), e27
DOI 10.1038/ctg.2012.21, PubMed 23324654 -
Fatty acids in habitual diet, plasma phospholipids, and tumour and normal colonic biopsies in young colorectal cancer patients
J Oncol, 2012, 254801
DOI 10.1155/2012/254801, PubMed 23319946 -
Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells
Arterioscler Thromb Vasc Biol, 33 (2), e47-55
DOI 10.1161/ATVBAHA.112.253427, PubMed 23162017 -
Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study
Ann Oncol, 24 (1), 152-60
DOI 10.1093/annonc/mds276, PubMed 22967994 -
The alarmin IL-33 is a notch target in quiescent endothelial cells
Am J Pathol, 181 (3), 1099-111
DOI 10.1016/j.ajpath.2012.06.003, PubMed 22809957
Publications 2011
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Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
PLoS One, 6 (9), e24419
DOI 10.1371/journal.pone.0024419, PubMed 21909432 -
Evaluation of right ventricular dysfunction by myocardial strain echocardiography in patients with intestinal carcinoid disease
J Am Soc Echocardiogr, 24 (6), 644-50
DOI 10.1016/j.echo.2011.02.009, PubMed 21440415 -
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
Mol Cancer, 10, 85
DOI 10.1186/1476-4598-10-85, PubMed 21777459 -
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
DOI 10.1038/onc.2011.109, PubMed 21499309 -
Evaluation of disease activity in IBD at the time of diagnosis by the use of clinical, biochemical, and fecal markers
Scand J Gastroenterol, 46 (9), 1081-91
DOI 10.3109/00365521.2011.584897, PubMed 21619483 -
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
Genes Immun, 12 (8), 653-62
DOI 10.1038/gene.2011.43, PubMed 21716316
Publications 2010
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Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
Mol Cancer, 9, 100
DOI 10.1186/1476-4598-9-100, PubMed 20459617 -
DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
PLoS One, 5 (11), e13978
DOI 10.1371/journal.pone.0013978, PubMed 21103049 -
Activin A in carcinoid heart disease: a possible role in diagnosis and pathogenesis
Neuroendocrinology, 92 (3), 168-77
DOI 10.1159/000318014, PubMed 20720391 -
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
DOI 10.1186/1471-2407-10-6, PubMed 20053285 -
Nordic Guidelines 2010 for diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours
Acta Oncol, 49 (6), 740-56
DOI 10.3109/0284186X.2010.492791, PubMed 20553100 -
Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts
Am J Pathol, 177 (6), 2804-15
DOI 10.2353/ajpath.2010.100378, PubMed 21037074
Publications 2009
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Small intestinal neuroendocrine tumors: prognostic factors and survival
Scand J Gastroenterol, 44 (9), 1084-91
DOI 10.1080/00365520903082432, PubMed 19572232 -
Interleukin-33 - cytokine of dual function or novel alarmin?
Trends Immunol, 30 (5), 227-33
DOI 10.1016/j.it.2009.03.003, PubMed 19359217 -
Treatment of fulminant ulcerative colitis with cyclosporine A
Scand J Gastroenterol, 44 (11), 1310-4
DOI 10.3109/00365520903222673, PubMed 19891581
Publications 2008
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Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
Mol Cancer, 7, 94
DOI 10.1186/1476-4598-7-94, PubMed 19117505 -
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
Am J Pathol, 173 (4), 1229-42
DOI 10.2353/ajpath.2008.080014, PubMed 18787100 -
Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
J Transl Med, 6, 13
DOI 10.1186/1479-5876-6-13, PubMed 18346269
Publications 2006
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ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
Cell Oncol, 28 (5-6), 259-72
DOI 10.1155/2006/949506, PubMed 17167179 -
ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
Cell. Oncol., 28 (5-6), 259-272 -
Impact of a colonoscopic screening examination for colorectal cancer on later utilization of distal GI endoscopies
Gastrointest Endosc, 64 (6), 948-54
DOI 10.1016/j.gie.2006.08.006, PubMed 17140903
Publications 2005
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Carbon dioxide insufflation in colonoscopy: safe and effective in sedated patients
Endoscopy, 37 (8), 706-9
DOI 10.1055/s-2005-870154, PubMed 16032487
Publications 2004
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Testing for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT)
Gut, 53 (9), 1329-33
DOI 10.1136/gut.2004.039032, PubMed 15306594
Publications 2003
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Air and carbon dioxide volumes insufflated during colonoscopy
Gastrointest Endosc, 58 (2), 203-6
DOI 10.1067/mge.2003.340, PubMed 12872086 -
Inter-endoscopist variation in polyp and neoplasia pick-up rates in flexible sigmoidoscopy screening for colorectal cancer
Scand J Gastroenterol, 38 (12), 1268-74
DOI 10.1080/00365520310006513, PubMed 14750648
Publications 2002
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Carbon dioxide insufflation reduces discomfort due to flexible sigmoidoscopy in colorectal cancer screening
Scand J Gastroenterol, 37 (9), 1103-7
DOI 10.1080/003655202320378329, PubMed 12374237 -
Use of a disposable sheath system for flexible sigmoidoscopy in decentralized colorectal cancer screening
Endoscopy, 34 (10), 814-8
DOI 10.1055/s-2002-34273, PubMed 12244504 -
NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopy
Gut, 50 (5), 604-7
DOI 10.1136/gut.50.5.604, PubMed 11950803 -
Screening for sporadic colorectal cancer
Endoscopy, 34 (6), 508; author reply 509-10
DOI 10.1055/s-2002-31993, PubMed 12048642
Publications 2001
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Do undesirable effects of screening affect all-cause mortality in flexible sigmoidoscopy programmes? Experience from the Telemark Polyp Study 1983-1996
Eur J Cancer Prev, 10 (2), 131-7
DOI 10.1097/00008469-200104000-00003, PubMed 11330453 -
The effect of attending a flexible sigmoidoscopic screening program on the prevalence of colorectal adenomas at 13-year follow-up
Am J Gastroenterol, 96 (6), 1901-7
DOI 10.1111/j.1572-0241.2001.03891.x, PubMed 11419846
Publications 2000
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Patient tolerance of colonoscopy without sedation during screening examination for colorectal polyps
Gastrointest Endosc, 52 (5), 606-10
DOI 10.1067/mge.2000.109804, PubMed 11060183
Publications 1999
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Population-based surveillance by colonoscopy: effect on the incidence of colorectal cancer. Telemark Polyp Study I
Scand J Gastroenterol, 34 (4), 414-20
DOI 10.1080/003655299750026443, PubMed 10365903 -
Flexible sigmoidoscopy or colonoscopy as a screening modality for colorectal adenomas in older age groups? Findings in a cohort of the normal population aged 63-72 years
Gut, 45 (6), 834-9
DOI 10.1136/gut.45.6.834, PubMed 10562581 -
The psychologic effect of attending a screening program for colorectal polyps
Scand J Gastroenterol, 34 (1), 103-9
DOI 10.1080/00365529950172916, PubMed 10048741
Publications 1997
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[Integration of preventive medicine in an emergency department. A pedagogic model for improvement of communication]
Tidsskr Nor Laegeforen, 117 (13), 1918-21
PubMed 9214014 -
[Long-term result of a life style intervention group program]
Tidsskr Nor Laegeforen, 117 (13), 1913-6
PubMed 9214013
Publications 1996
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Polypectomy of adenomas in the prevention of colorectal cancer: 10 years' follow-up of the Telemark Polyp Study I. A prospective, controlled population study
Scand J Gastroenterol, 31 (10), 1006-10
DOI 10.3109/00365529609003121, PubMed 8898422