Hilde Nilsen group
We study how DNA repair impact human health in a life course perspective. We study how DNA repair mechanisms protect us from ageing and age-related diseases and use iPSC to model human DNA repair diseases and determine functional consequences in different cell types. We are particularly interested to model motoneurons. We also use patient derived iPCS of the rare DNA repair syndrome Ataxia Telangiectasia to look at genotype-phenotype relationships.