PubMed registered articles Ola Myklebost
Publications published since 1983 by Ola Myklebost
186 publications found
Publications 2023
-
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
Science, 379 (6629), 253-260
DOI 10.1126/science.abj4784, PubMed 36656928 -
Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
Mol Oncol (in press)
DOI 10.1002/1878-0261.13514, PubMed 37622176
Publications 2022
-
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
Leukemia, 36 (7), 1887-1897
DOI 10.1038/s41375-022-01597-y, PubMed 35643867 -
miR-486-5p expression is regulated by DNA methylation in osteosarcoma
BMC Genomics, 23 (1), 142
DOI 10.1186/s12864-022-08346-6, PubMed 35172717 -
Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
Genome Med, 14 (1), 86
DOI 10.1186/s13073-022-01090-2, PubMed 35948919
Publications 2021
-
Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
Pathology, 53 (6), 713-719
DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702 -
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140
DOI 10.1371/journal.pone.0248140, PubMed 33690666 -
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
Int J Cancer, 149 (11), 1955-1960
DOI 10.1002/ijc.33749, PubMed 34310709 -
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
Nat Commun, 12 (1), 3230
DOI 10.1038/s41467-021-23445-w, PubMed 34050156 -
Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
Biochem Biophys Res Commun, 552, 91-97
DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765 -
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667
Publications 2020
-
Cell Fusion of Mesenchymal Stem/Stromal Cells and Breast Cancer Cells Leads to the Formation of Hybrid Cells Exhibiting Diverse and Individual (Stem Cell) Characteristics
Int J Mol Sci, 21 (24)
DOI 10.3390/ijms21249636, PubMed 33348862 -
Accurate 3-gene-signature for early diagnosis of liposarcoma progression
Clin Sarcoma Res, 10, 4
DOI 10.1186/s13569-020-0126-1, PubMed 32158531 -
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Blood Adv, 4 (9), 1859-1866
DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
Publications 2019
-
Preclinical Evaluation of the Pan-FGFR Inhibitor LY2874455 in FRS2-Amplified Liposarcoma
Cells, 8 (2)
DOI 10.3390/cells8020189, PubMed 30795553
Publications 2018
-
Patterns of genomic evolution in advanced melanoma
Nat Commun, 9 (1), 2665
DOI 10.1038/s41467-018-05063-1, PubMed 29991680 -
Preclinical Evaluation of Vemurafenib as Therapy for BRAFV600E Mutated Sarcomas
Int J Mol Sci, 19 (4)
DOI 10.3390/ijms19040969, PubMed 29570692 -
Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples
PLoS One, 13 (5), e0197456
DOI 10.1371/journal.pone.0197456, PubMed 29771965 -
Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
Eur Urol, 75 (3), 498-505
DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068 -
Personal Cancer Genome Reporter: variant interpretation report for precision oncology
Bioinformatics, 34 (10), 1778-1780
DOI 10.1093/bioinformatics/btx817, PubMed 29272339 -
Noninvasive Detection of ctDNA Reveals Intratumor Heterogeneity and Is Associated with Tumor Burden in Gastrointestinal Stromal Tumor
Mol Cancer Ther, 17 (11), 2473-2480
DOI 10.1158/1535-7163.MCT-18-0174, PubMed 30097488 -
Real-Time Vital Mineralization Detection and Quantification during In Vitro Osteoblast Differentiation
Biol Proced Online, 20, 14
DOI 10.1186/s12575-018-0079-4, PubMed 30078998 -
Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma
Clin. Sarcoma Res., 8, 17
DOI 10.1186/s13569-018-0103-0 -
Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sci Rep, 8 (1), 5307
DOI 10.1038/s41598-018-23563-4, PubMed 29593270
Publications 2017
-
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
Nat Commun, 8, 15936
DOI 10.1038/ncomms15936, PubMed 28643781 -
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
Mol Cancer, 16 (1), 116
DOI 10.1186/s12943-017-0691-y, PubMed 28683746 -
Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b
Sci Rep, 7 (1), 9655
DOI 10.1038/s41598-017-10189-1, PubMed 28848235 -
High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
Int J Cancer, 141 (1), 184-190
DOI 10.1002/ijc.30726, PubMed 28387924 -
Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
BMC Cancer, 17 (1), 29
DOI 10.1186/s12885-016-2992-8, PubMed 28061772 -
Monitoring multiple myeloma by quantification of recurrent mutations in serum
Haematologica, 102 (7), 1266-1272
DOI 10.3324/haematol.2016.160564, PubMed 28385781 -
PP2A Regulatory Subunit B55γ is a Gatekeeper of Osteoblast Maturation and Lineage Maintenance
Stem Cells Dev, 26 (19), 1375-1383
DOI 10.1089/scd.2017.0129, PubMed 28805158 -
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Genome Med, 9 (1), 46
DOI 10.1186/s13073-017-0434-0, PubMed 28539123
Publications 2016
-
Monogenic and polygenic determinants of sarcoma risk: an international genetic study
Lancet Oncol, 17 (9), 1261-71
DOI 10.1016/S1470-2045(16)30147-4, PubMed 27498913 -
Genome Analysis of Osteosarcoma Progression Samples Identifies FGFR1 Overexpression as a Potential Treatment Target and CHM as a Candidate Tumor Suppressor Gene
PLoS One, 11 (9), e0163859
DOI 10.1371/journal.pone.0163859, PubMed 27685995 -
TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
Front Genet, 7, 85
DOI 10.3389/fgene.2016.00085, PubMed 27242894 -
Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma
Oncotarget, 7 (34), 54583-54595
DOI 10.18632/oncotarget.10518, PubMed 27409346 -
Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Genome Res, 26 (5), 717.2
DOI 10.1101/gr.206557.116, PubMed 27197245 -
The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report
Clin Sarcoma Res, 6, 3
DOI 10.1186/s13569-016-0043-5, PubMed 27315524 -
Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
Oncotarget, 7 (5), 5273-88
DOI 10.18632/oncotarget.6567, PubMed 26672768 -
HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo
Oncotarget, 7 (1), 433-45
DOI 10.18632/oncotarget.6336, PubMed 26595521 -
The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Cancer Res, 76 (17), 5092-102
DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532
Publications 2015
-
Genome sequencing in research requires a new approach to consent
Tidsskr Nor Laegeforen, 135 (22), 2031-2
DOI 10.4045/tidsskr.15.0944, PubMed 26627287 -
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Genome Res, 25 (6), 814-24
DOI 10.1101/gr.190470.115, PubMed 25963125 -
Genomic landscape of liposarcoma
Oncotarget, 6 (40), 42429-44
DOI 10.18632/oncotarget.6464, PubMed 26643872 -
Personalized cancer therapy for soft tissue sarcomas: progress and pitfalls
Per Med, 12 (6), 593-602
DOI 10.2217/pme.15.20, PubMed 29750616 -
Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
Mol Cancer, 14 (1), 14
DOI 10.1186/s12943-014-0278-9, PubMed 25623255 -
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
Blood Cancer J, 5 (3), e299
DOI 10.1038/bcj.2015.24, PubMed 25794135 -
Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA
Oncotarget, 6 (4), 2451-65
DOI 10.18632/oncotarget.3235, PubMed 25669981
Publications 2014
-
Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology
Clin. Sarcoma Res., 4, 4
DOI 10.1186/2045-3329-4-4 -
Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model
Mol Cancer, 13, 93
DOI 10.1186/1476-4598-13-93, PubMed 24885297 -
Performance comparison of four exome capture systems for deep sequencing
BMC Genomics, 15 (1), 449
DOI 10.1186/1471-2164-15-449, PubMed 24912484 -
The architecture and evolution of cancer neochromosomes
Cancer Cell, 26 (5), 653-67
DOI 10.1016/j.ccell.2014.09.010, PubMed 25517748 -
The regulatory landscape of osteogenic differentiation
Stem Cells, 32 (10), 2780-93
DOI 10.1002/stem.1759, PubMed 24898411 -
Generation and characterization of an immortalized human mesenchymal stromal cell line
Stem Cells Dev, 23 (19), 2377-89
DOI 10.1089/scd.2013.0599, PubMed 24857590 -
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
Science, 345 (6196), 1251343
DOI 10.1126/science.1251343, PubMed 25082706 -
Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
PLoS One, 9 (8), e103873
DOI 10.1371/journal.pone.0103873, PubMed 25148029
Publications 2013
-
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
Nat Genet, 45 (12), 1479-82
DOI 10.1038/ng.2814, PubMed 24162739 -
Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas
Genes Chromosomes Cancer, 52 (6), 580-90
DOI 10.1002/gcc.22055, PubMed 23508853 -
A small molecule approach to engineering vascularized tissue
Biomaterials, 34 (12), 3053-63
DOI 10.1016/j.biomaterials.2012.12.037, PubMed 23369216 -
IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma
BMC Cancer, 13, 245
DOI 10.1186/1471-2407-13-245, PubMed 23688189 -
Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes
Br J Cancer, 109 (8), 2228-36
DOI 10.1038/bjc.2013.549, PubMed 24064976 -
Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
Transl Oncol, 6 (5), 546-53
DOI 10.1593/tlo.13457, PubMed 24151535 -
Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome
Exp Cell Res, 319 (14), 2230-43
DOI 10.1016/j.yexcr.2013.06.004, PubMed 23791939 -
Epigenetic regulation and functional characterization of microRNA-142 in mesenchymal cells
PLoS One, 8 (11), e79231
DOI 10.1371/journal.pone.0079231, PubMed 24236112 -
Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
Biochim Biophys Acta, 1830 (8), 4235-43
DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966 -
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines
Cancer Med, 3 (1), 36-46
DOI 10.1002/cam4.170, PubMed 24403055
Publications 2012
-
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma
PLoS One, 7 (11), e48262
DOI 10.1371/journal.pone.0048262, PubMed 23144859 -
Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
Genes Chromosomes Cancer, 51 (7), 696-706
DOI 10.1002/gcc.21956, PubMed 22454324 -
Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern
Sarcoma, 2012, 639038
DOI 10.1155/2012/639038, PubMed 22518090 -
Modulation of the osteosarcoma expression phenotype by microRNAs
PLoS One, 7 (10), e48086
DOI 10.1371/journal.pone.0048086, PubMed 23133552 -
Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma
Cancer, 119 (5), 1013-22
DOI 10.1002/cncr.27837, PubMed 23165797 -
[Genome sequencing for personalized cancer treatment]
Tidsskr Nor Laegeforen, 132 (21), 2406-8
DOI 10.4045/tidsskr.12.0784, PubMed 23160594 -
Characterization of liposarcoma cell lines for preclinical and biological studies
Sarcoma, 2012, 148614
DOI 10.1155/2012/148614, PubMed 22911243
Publications 2011
-
Tumor-infiltrating macrophages are associated with metastasis suppression in high-grade osteosarcoma: a rationale for treatment with macrophage activating agents
Clin Cancer Res, 17 (8), 2110-9
DOI 10.1158/1078-0432.CCR-10-2047, PubMed 21372215 -
Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
BMC Cancer, 11, 455
DOI 10.1186/1471-2407-11-455, PubMed 22014070 -
Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations
Cancer, 118 (2), 558-70
DOI 10.1002/cncr.26276, PubMed 21713766 -
mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts
BMC Med Genomics, 4, 66
DOI 10.1186/1755-8794-4-66, PubMed 21933437 -
MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
BMC Cancer, 11, 211:1-11
DOI 10.1186/1471-2407-11-211, PubMed 21624110 -
Adipocyte differentiation of human bone marrow-derived stromal cells is modulated by microRNA-155, microRNA-221, and microRNA-222
Stem Cells Dev, 21 (6), 873-83
DOI 10.1089/scd.2010.0503, PubMed 21756067 -
Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
Clin Sarcoma Res, 1 (1), 8
DOI 10.1186/2045-3329-1-8, PubMed 22612877 -
Workshop Report on the European Bone Sarcoma Networking Meeting: Integration of Clinical Trials with Tumor Biology
J Adolesc Young Adult Oncol, 1 (3), 118-23
DOI 10.1089/jayao.2012.0005, PubMed 26811922
Publications 2010
-
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
Blood, 116 (9), 1489-97
DOI 10.1182/blood-2010-03-272278, PubMed 20505157 -
Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells
BMC Cancer, 10, 329
DOI 10.1186/1471-2407-10-329, PubMed 20576167 -
DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation
PLoS One, 5 (11), e15378
DOI 10.1371/journal.pone.0015378, PubMed 21085701 -
Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours
BMC Res Notes, 3, 223
DOI 10.1186/1756-0500-3-223, PubMed 20691109 -
A tissue microarray study of osteosarcoma: histopathologic and immunohistochemical validation of xenotransplanted tumors as preclinical models
Appl Immunohistochem Mol Morphol, 18 (5), 453-61
DOI 10.1097/PAI.0b013e3181daace3, PubMed 20436344 -
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort
Genes Chromosomes Cancer, 49 (1), 40-51
DOI 10.1002/gcc.20717, PubMed 19787792 -
Extensive adipogenic and osteogenic differentiation of patterned human mesenchymal stem cells in a microfluidic device
Lab Chip, 10 (11), 1401-1409
DOI 10.1039/b926738g, PubMed 20386793
Publications 2009
-
LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization
Genes Chromosomes Cancer, 48 (8), 679-93
DOI 10.1002/gcc.20675, PubMed 19441093 -
Upregulation of stem cell genes in multidrug resistant K562 leukemia cells
Leuk Res, 33 (10), 1379-85
DOI 10.1016/j.leukres.2009.03.028, PubMed 19394083 -
Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: Role of TGF beta/BMP-6 and TIEG1 in chemotherapy escape. (vol 123, pg 2759, 2008)
Int. J. Cancer, 124 (9), 2250
DOI 10.1002/ijc.24300
Publications 2008
-
DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH
Mol Cancer, 7, 48
DOI 10.1186/1476-4598-7-48, PubMed 18522746 -
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
Genome Biol, 9 (5), R86
DOI 10.1186/gb-2008-9-5-r86, PubMed 18500990 -
High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence
J Cell Mol Med, 12 (2), 553-63
DOI 10.1111/j.1582-4934.2007.00146.x, PubMed 18419597 -
Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization
Oncol Rep, 20 (4), 825-43
DOI 10.3892/or_00000080, PubMed 18813824
Publications 2007
-
Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential
BMC Genomics, 8, 73
DOI 10.1186/1471-2164-8-73, PubMed 17359542 -
Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
Mol Cancer, 6, 2
DOI 10.1186/1476-4598-6-2, PubMed 17201907 -
Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A
Int J Cancer, 121 (1), 199-205
DOI 10.1002/ijc.22643, PubMed 17354236
Publications 2006
-
Sampling effects on gene expression data from a human tumour xenograft
Scand. J. Lab. Anim. Sci., 33 (1), 17-30 -
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Nat Biotechnol, 24 (9), 1151-61
DOI 10.1038/nbt1239, PubMed 16964229 -
Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas
Cancer Res, 66 (18), 8984-93
DOI 10.1158/0008-5472.CAN-06-1972, PubMed 16982739 -
Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas
Leukemia, 20 (3), 539-42
DOI 10.1038/sj.leu.2404094, PubMed 16437153 -
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy
Proc Natl Acad Sci U S A, 103 (6), 1888-93
DOI 10.1073/pnas.0507493103, PubMed 16443686
Publications 2005
-
Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
J Neuropathol Exp Neurol, 64 (1), 74-81
DOI 10.1093/jnen/64.1.74, PubMed 15715087 -
[Molecular genetics in the diagnosis of bone and soft tissue tumours]
Tidsskr Nor Laegeforen, 125 (23), 3286-9
PubMed 16327856 -
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
Leukemia, 19 (12), 2313-23
DOI 10.1038/sj.leu.2403954, PubMed 16193090 -
Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH
Mol Cancer, 4, 39
DOI 10.1186/1476-4598-4-39, PubMed 16274472 -
Response of malignant B lymphocytes to ionizing radiation: gene expression and genotype
Int J Cancer, 115 (6), 935-42
DOI 10.1002/ijc.20962, PubMed 15723354 -
Limitations of mRNA amplification from small-size cell samples
BMC Genomics, 6, 147
DOI 10.1186/1471-2164-6-147, PubMed 16253144
Publications 2004
-
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
DOI 10.1002/pmic.200300768, PubMed 15352232 -
Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
BMC Genomics, 5 (1), 10
DOI 10.1186/1471-2164-5-10, PubMed 15018648 -
Putting Norway on the gene-therapy map
Nature, 429 (6988), 129
DOI 10.1038/429129b, PubMed 15141186 -
Lessons from genetic profiling in soft tissue sarcomas
Acta Orthop Scand Suppl, 75 (311), 35-50
DOI 10.1080/00016470410001708310, PubMed 15188664 -
Amplification of chromosome 1 sequences in lipomatous tumors and other sarcomas
Int J Cancer, 109 (3), 363-9
DOI 10.1002/ijc.11716, PubMed 14961574 -
Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
J Mol Diagn, 6 (4), 297-307
DOI 10.1016/S1525-1578(10)60525-9, PubMed 15507668 -
M-CGH: analysing microarray-based CGH experiments
BMC Bioinformatics, 5, 74
DOI 10.1186/1471-2105-5-74, PubMed 15189572
Publications 2003
-
Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
Br J Cancer, 88 (12), 1995-2001
DOI 10.1038/sj.bjc.6600998, PubMed 12799648 -
Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
Oncogene, 22 (34), 5358-61
DOI 10.1038/sj.onc.1206671, PubMed 12917637 -
11q13 alterations in two cases of hibernoma: large heterozygous deletions and rearrangement breakpoints near GARP in 11q13.5
Genes Chromosomes Cancer, 37 (4), 389-95
DOI 10.1002/gcc.10223, PubMed 12800150 -
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
BMC Genomics, 4 (1), 11
DOI 10.1186/1471-2164-4-11, PubMed 12659661 -
Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data
BMC Bioinformatics, 4, 60
DOI 10.1186/1471-2105-4-60, PubMed 14651757 -
MGraph: graphical models for microarray data analysis
Bioinformatics, 19 (17), 2210-1
DOI 10.1093/bioinformatics/btg298, PubMed 14630649
Publications 2002
-
Analysis of repeatability in spotted cDNA microarrays
Nucleic Acids Res, 30 (14), 3235-44
DOI 10.1093/nar/gkf441, PubMed 12136105 -
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21
Oncogene, 21 (14), 2261-9
DOI 10.1038/sj.onc.1205339, PubMed 11948409 -
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
BMC Bioinformatics, 3, 36
DOI 10.1186/1471-2105-3-36, PubMed 12445336 -
MArray: analysing single, replicated or reversed microarray experiments
Bioinformatics, 18 (8), 1139-40
DOI 10.1093/bioinformatics/18.8.1139, PubMed 12176840 -
The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11.2; q11.2) and the cell cycle machinery
Oncogene, 21 (37), 5791-6
DOI 10.1038/sj.onc.1205700, PubMed 12173050
Publications 2001
-
A well-differentiated liposarcoma with a new type of chromosome 12-derived markers
Cancer Genet Cytogenet, 131 (1), 13-8
DOI 10.1016/s0165-4608(01)00516-7, PubMed 11734312 -
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity
Oncogene, 20 (47), 6881-90
DOI 10.1038/sj.onc.1204874, PubMed 11687967 -
Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma: amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases
Cancer Genet Cytogenet, 125 (2), 100-11
DOI 10.1016/s0165-4608(00)00369-1, PubMed 11369052 -
[Microarray technology--potential in cancer research]
Tidsskr Nor Laegeforen, 121 (21), 2498-503
PubMed 11875927 -
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868 -
Ectopic sequences from truncated HMGIC in liposarcomas are derived from various amplified chromosomal regions
Genes Chromosomes Cancer, 31 (3), 264-73
DOI 10.1002/gcc.1143, PubMed 11391797 -
[Measurement of gene activity by DNA microarrays]
Tidsskr Nor Laegeforen, 121 (10), 1225-8
PubMed 11402749
Publications 2000
-
Frequent loss of 9p21 (p16(INK4A)) and other genomic imbalances in human malignant fibrous histiocytoma
Cancer Genet Cytogenet, 118 (2), 89-98
DOI 10.1016/s0165-4608(99)00178-8, PubMed 10748288 -
Characterization of centromere alterations in liposarcomas
Genes Chromosomes Cancer, 29 (2), 117-29
DOI 10.1002/1098-2264(2000)9999:9999<::aid-gcc1014>3.0.co;2-q, PubMed 10959091
Publications 1999
-
Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors: studies of CDKN2A and other genes of the pRB pathway
Genes Chromosomes Cancer, 26 (2), 151-60
DOI 10.1002/(SICI)1098-2264(199910)26:2<151::AID-GCC7>3.0.CO;2-A, PubMed 10469453 -
Sensitive fluorescent in situ hybridisation method for the characterisation of breast cancer cells in bone marrow aspirates
Mol Pathol, 52 (2), 68-74
DOI 10.1136/mp.52.2.68, PubMed 10474684 -
Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors
Genes Chromosomes Cancer, 24 (1), 30-41
DOI 10.1002/(SICI)1098-2264(199901)24:1<30::AID-GCC5>3.3.CO;2-G, PubMed 9892106 -
A novel chromosomal region of allelic loss, 4q32-q34, in human osteosarcomas revealed by representational difference analysis
Genes Chromosomes Cancer, 26 (2), 115-24
DOI 10.1002/(SICI)1098-2264(199910)26:2<115::AID-GCC3>3.0.CO;2-E, PubMed 10469449 -
Characterization of the 17p amplicon in human sarcomas: microsatellite marker analysis
Int J Cancer, 82 (3), 329-33
DOI 10.1002/(sici)1097-0215(19990730)82:3<329::aid-ijc4>3.0.co;2-1, PubMed 10399948
Publications 1998
-
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas
Br J Cancer, 78 (4), 495-503
DOI 10.1038/bjc.1998.521, PubMed 9716033 -
[Molecular biology diagnosis of sarcoma]
Tidsskr Nor Laegeforen, 118 (14), 2188-93
PubMed 9656816 -
GLI gene and rhabdomyosarcoma
Nat Med, 4 (8), 869
DOI 10.1038/nm0898-869c, PubMed 9701218
Publications 1997
-
Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization
Br J Cancer, 75 (10), 1403-9
DOI 10.1038/bjc.1997.242, PubMed 9166930 -
HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas
Oncogene, 14 (24), 2935-41
DOI 10.1038/sj.onc.1201135, PubMed 9205100 -
Molecular cytogenetics of bone and soft tissue tumors
Cancer Genet Cytogenet, 95 (1), 67-73
DOI 10.1016/s0165-4608(96)00241-5, PubMed 9140455 -
Complexity of 12q13-22 amplicon in liposarcoma: microsatellite repeat analysis
Genes Chromosomes Cancer, 18 (1), 66-70
DOI 10.1002/(sici)1098-2264(199701)18:1<66::aid-gcc8>3.0.co;2-#, PubMed 8993982
Publications 1996
-
Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas
Genes Chromosomes Cancer, 17 (4), 254-9
DOI 10.1002/(SICI)1098-2264(199612)17:4<254::AID-GCC7>3.0.CO;2-2, PubMed 8946207 -
Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme
Cancer Res, 56 (23), 5490-8
PubMed 8968106 -
First for biotech
Nature, 384 (6606), 208
DOI 10.1038/384208b0, PubMed 8918866
Publications 1995
-
Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas
Genes Chromosomes Cancer, 14 (1), 15-21
DOI 10.1002/gcc.2870140104, PubMed 8527379 -
Comparative genomic hybridization analysis of human sarcomas: I. Occurrence of genomic imbalances and identification of a novel major amplicon at 1q21-q22 in soft tissue sarcomas
Genes Chromosomes Cancer, 14 (1), 8-14
DOI 10.1002/gcc.2870140103, PubMed 8527390 -
Cloning and characterization of two forms of bovine polymeric immunoglobulin receptor cDNA
DNA Cell Biol, 14 (3), 251-6
DOI 10.1089/dna.1995.14.251, PubMed 7880445 -
Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1
Br J Cancer, 72 (2), 393-8
DOI 10.1038/bjc.1995.344, PubMed 7640224 -
Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP
Cancer Genet Cytogenet, 82 (2), 151-4
DOI 10.1016/0165-4608(95)00034-m, PubMed 7664245
Publications 1994
-
Expression of the neuroectodermal intermediate filament nestin in human melanomas
Cancer Res, 54 (2), 354-6
PubMed 8275467 -
MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status
J Natl Cancer Inst, 86 (17), 1297-302
DOI 10.1093/jnci/86.17.1297, PubMed 8064888 -
The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas
Cancer Genet Cytogenet, 78 (2), 165-71
DOI 10.1016/0165-4608(94)90085-x, PubMed 7828148 -
A long range restriction map spanning the myxoid liposarcoma breakpoint in the q13-14 region of human chromosome 12
Hum Genet, 94 (3), 259-64
DOI 10.1007/BF00208280, PubMed 8076941 -
Comparative genomic hybridization as a tool to define two distinct chromosome 12-derived amplification units in well-differentiated liposarcomas
Genes Chromosomes Cancer, 9 (4), 292-5
DOI 10.1002/gcc.2870090410, PubMed 7519052
Publications 1993
-
CHROMOSOME-17P ABERRATIONS AND P53 EXPRESSION IN HUMAN SARCOMAS
FRONTIERS OF OSTEOSARCOMA RESEARCH: INTERDISCIPLINARY SURVEY OF CLINICAL AND RESEARCH ADVANCES, 419-422 -
p53 abnormalities in different subtypes of human sarcomas
Cancer Res, 53 (3), 468-71
PubMed 8425179 -
Isolation, sequencing, and expression analysis of a bovine apolipoprotein E (APOE) cDNA and chromosomal localization of the APOE locus
Mamm Genome, 4 (1), 53-7
DOI 10.1007/BF00364665, PubMed 8422503 -
Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2
Cell Growth Differ, 4 (12), 1065-70
PubMed 8117620
Publications 1992
-
Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
Cancer Res, 52 (21), 6088-91
PubMed 1356624 -
A physical map of a 1.3-Mb region on the long arm of chromosome 12, spanning the GLI and LRP loci
Genomics, 14 (1), 117-20
DOI 10.1016/s0888-7543(05)80292-7, PubMed 1427818 -
Uptake of chylomicron remnant retinyl esters in human leukocytes in vivo
Eur J Clin Invest, 22 (4), 229-34
DOI 10.1111/j.1365-2362.1992.tb01456.x, PubMed 1499639
Publications 1991
-
The human genes for complement components 6 (C6) and 9 (C9) are closely linked on chromosome 5
J Med Genet, 28 (9), 587-90
DOI 10.1136/jmg.28.9.587, PubMed 1683409
Publications 1990
-
Association analysis of lipid levels and apolipoprotein restriction fragment length polymorphisms
Hum Genet, 86 (2), 209-14
DOI 10.1007/BF00197707, PubMed 1979958 -
Multiple RFLPs of human complement component nine (C9) detected by TaqI
Nucleic Acids Res, 18 (10), 3112
DOI 10.1093/nar/18.10.3112-a, PubMed 1971940
Publications 1989
-
The gene for the human putative apoE receptor is on chromosome 12 in the segment q13-14
Genomics, 5 (1), 65-9
DOI 10.1016/0888-7543(89)90087-6, PubMed 2548950 -
Low-density-lipoprotein receptors in different rabbit liver cells
Biochem J, 261 (2), 587-93
DOI 10.1042/bj2610587, PubMed 2549976 -
The genes for apolipoprotein all (APOA2) and the Duffy blood group (FY) are linked on chromosome 1 in man
Genomics, 4 (2), 169-73
DOI 10.1016/0888-7543(89)90296-6, PubMed 2500391 -
The gene for human complement C9 is on chromosome 5
Genomics, 5 (1), 149-52
DOI 10.1016/0888-7543(89)90100-6, PubMed 2767685
Publications 1988
-
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
EMBO J, 7 (13), 4119-27
DOI 10.1002/j.1460-2075.1988.tb03306.x, PubMed 3266596 -
A physical map of the apolipoprotein gene cluster on human chromosome 19
Hum Genet, 78 (3), 244-7
DOI 10.1007/BF00291670, PubMed 2894348
Publications 1987
-
The isolation and characterisation of a cDNA clone for human lecithin:cholesterol acyl transferase and its use to analyse the genes in patients with LCAT deficiency and fish eye disease
Biochem Biophys Res Commun, 148 (1), 161-9
DOI 10.1016/0006-291x(87)91090-4, PubMed 2823801
Publications 1986
-
The gene for human apolipoprotein CI is located 4.3 kilobases away from the apolipoprotein E gene on chromosome 19
Hum Genet, 73 (4), 286-9
DOI 10.1007/BF00279087, PubMed 3017837 -
Confirmation of the close linkage between the loci for human apolipoproteins AI and AIV by the use of a cloned cDNA probe and two restriction site polymorphisms
Hum Genet, 72 (1), 68-71
DOI 10.1007/BF00278820, PubMed 3002953
Publications 1985
-
Cell cycle traverse and protein metabolism in human NHIK 3025 cells: the role of anchorage
J Cell Physiol, 125 (3), 528-32
DOI 10.1002/jcp.1041250324, PubMed 4066771 -
The apolipoprotein CII gene: subchromosomal localisation and linkage to the myotonic dystrophy locus
Hum Genet, 70 (3), 271-3
DOI 10.1007/BF00273455, PubMed 2991117
Publications 1984
-
Familial apolipoprotein CII deficiency: a preliminary analysis of the gene defect in two independent families
Hum Genet, 67 (2), 151-5
DOI 10.1007/BF00272990, PubMed 6547689 -
The locus for apolipoprotein CII is closely linked to the apolipoprotein E locus on chromosome 19 in man
Hum Genet, 67 (3), 309-12
DOI 10.1007/BF00291359, PubMed 6088388 -
The isolation and characterization of cDNA clones for human apolipoprotein CII
J Biol Chem, 259 (7), 4401-4
PubMed 6546757
Publications 1983
-
A DNA polymorphism adjacent to the human apolipoprotein CII gene
Mol Biol Med, 1 (5), 463-71
PubMed 6094958