
Håvard E. Danielsen
- Professor, Science Director; PhD
- (+47) 906 08 723
Publications 2023
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets
J Pathol Clin Res (in press)
DOI 10.1002/cjp2.342, PubMed 37697694
Publications 2022
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study
Lancet Oncol, 23 (9), 1221-1232
DOI 10.1016/S1470-2045(22)00391-6, PubMed 35964620
The Essentials of Multiomics
Oncologist, 27 (4), 272-284
DOI 10.1093/oncolo/oyab048, PubMed 35380712
Publications 2021
PTEN and DNA Ploidy Status by Machine Learning in Prostate Cancer
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174291, PubMed 34503100
Automated assessment of CD8+ T-lymphocytes and stroma fractions complement conventional staging of colorectal cancer
EBioMedicine, 71, 103547
DOI 10.1016/j.ebiom.2021.103547, PubMed 34479131
Stromal composition predicts recurrence of early rectal cancer after local excision
Histopathology, 79 (6), 947-956
DOI 10.1111/his.14438, PubMed 34174109
Designing deep learning studies in cancer diagnostics
Nat Rev Cancer, 21 (3), 199-211
DOI 10.1038/s41568-020-00327-9, PubMed 33514930
Deep learning and cancer biomarkers: recognising lead-time bias - Authors' reply
Lancet, 397 (10270), 194-195
DOI 10.1016/S0140-6736(21)00035-0, PubMed 33453777
Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Prostate, 81 (12), 838-848
DOI 10.1002/pros.24180, PubMed 34125445
Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression
Cancer Res, 81 (15), 4066-4078
DOI 10.1158/0008-5472.CAN-20-3956, PubMed 34183356
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864
Publications 2020
Prognostic value of DNA ploidy and automated assessment of stroma fraction in prostate cancer
Int J Cancer, 147 (4), 1228-1234
DOI 10.1002/ijc.32832, PubMed 31846064
Prognostic Value of the Diversity of Nuclear Chromatin Compartments in Gynaecological Carcinomas
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123838, PubMed 33352679
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
Lancet, 395 (10221), 350-360
DOI 10.1016/S0140-6736(19)32998-8, PubMed 32007170
Publications 2019
Prognostic value of mitotic checkpoint protein BUB3, cyclin B1, and pituitary tumor-transforming 1 expression in prostate cancer
Mod Pathol, 33 (5), 905-915
DOI 10.1038/s41379-019-0418-2, PubMed 31801961
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
Br J Cancer, 121 (6), 474-482
DOI 10.1038/s41416-019-0540-4, PubMed 31388185
Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
Br J Cancer, 121 (9), 807
DOI 10.1038/s41416-019-0590-7, PubMed 31548598
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer
Oncogene, 38 (35), 6301-6318
DOI 10.1038/s41388-019-0879-2, PubMed 31312022
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Nat Commun, 10 (1), 323
DOI 10.1038/s41467-018-08152-3, PubMed 30679434
Publications 2018
Prognostic markers for colorectal cancer: estimating ploidy and stroma
Ann Oncol, 29 (3), 616-623
DOI 10.1093/annonc/mdx794, PubMed 29293881
Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series
Lancet Gastroenterol Hepatol, 3 (9), 635-643
DOI 10.1016/S2468-1253(18)30117-1, PubMed 30042065
Chromatin organisation and cancer prognosis: a pan-cancer study
Lancet Oncol, 19 (3), 356-369
DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700
Clinical utility of chromatin analysis
Oncotarget, 9 (65), 32406-32407
DOI 10.18632/oncotarget.25991, PubMed 30197751
Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers
J Natl Cancer Inst, 110 (12), 1400-1408
DOI 10.1093/jnci/djy063, PubMed 29684152
Publications 2017
Computer-aided diagnostics in digital pathology
Cytometry A, 91 (6), 551-554
DOI 10.1002/cyto.a.23151, PubMed 28640523
Tumour heterogeneity poses a significant challenge to cancer biomarker research
Br J Cancer, 117 (3), 367-375
DOI 10.1038/bjc.2017.171, PubMed 28618431
Neuron navigator-2 and cyclin D2 are new candidate prognostic markers in uterine sarcoma
Virchows Arch, 471 (3), 355-362
DOI 10.1007/s00428-017-2172-5, PubMed 28643014
[Properties of cancer cell DNA affects the prognosis]
Tidsskr Nor Laegeforen, 137 (19)
DOI 10.4045/tidsskr.16.0966, PubMed 29043733
Characteristics of tumor cell DNA affect prognosis
Tidsskr. Nor. Laegeforen., 137 (19), 1519-1523
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer
Cancer Cell, 31 (1), 79-93
DOI 10.1016/j.ccell.2016.11.001, PubMed 28073006
Assessment of DNA Ploidy in the ProMisE molecular subgroups of endometrial cancer
Gynecol Oncol, 146 (3), 596-602
DOI 10.1016/j.ygyno.2017.06.020, PubMed 28647100
Overexpression of integrin α11 induces cardiac fibrosis in mice
Acta Physiol (Oxf), 222 (2)
DOI 10.1111/apha.12932, PubMed 28771943
Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
Cardiovasc Res, 113 (10), 1161-1172
DOI 10.1093/cvr/cvx087, PubMed 28472418
Publications 2016
Progesterone Receptor Expression Is an Independent Prognosticator in FIGO Stage I Uterine Leiomyosarcoma
Am J Clin Pathol, 145 (4), 449-58
DOI 10.1093/ajcp/aqw030, PubMed 27149024
Chromatin changes predict recurrence after radical prostatectomy
Br J Cancer, 114 (11), 1243-50
DOI 10.1038/bjc.2016.96, PubMed 27124335
Changes in Chromatin Structure in Curettage Specimens Identifies High-Risk Patients in Endometrial Cancer
Cancer Epidemiol Biomarkers Prev, 26 (1), 61-67
DOI 10.1158/1055-9965.EPI-16-0215, PubMed 27587790
Cancer Prognosis Defined by the Combined Analysis of 8q, PTEN and ERG
Transl Oncol, 9 (6), 575-582
DOI 10.1016/j.tranon.2016.08.005, PubMed 27916292
Publications 2015
Computerized image analysis of the Ki-67 proliferation index in mantle cell lymphoma
Histopathology, 67 (1), 62-9
DOI 10.1111/his.12624, PubMed 25431344
Revisiting tumour aneuploidy - the place of ploidy assessment in the molecular era
Nat Rev Clin Oncol, 13 (5), 291-304
DOI 10.1038/nrclinonc.2015.208, PubMed 26598944
STAMP2 increases oxidative stress and is critical for prostate cancer
EMBO Mol Med, 7 (3), 315-31
DOI 10.15252/emmm.201404181, PubMed 25680860
Correction: TCTP is an androgen-regulated gene implicated in prostate cancer
PLoS One, 10 (5), e0128727
DOI 10.1371/journal.pone.0128727, PubMed 25973603
DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer
Br J Cancer, 112 (10), 1656-64
DOI 10.1038/bjc.2015.123, PubMed 25897678
Divergent androgen regulation of unfolded protein response pathways drives prostate cancer
EMBO Mol Med, 7 (6), 788-801
DOI 10.15252/emmm.201404509, PubMed 25864123
Publications 2014
Prognostic impact of genomic instability in colorectal cancer
Br J Cancer, 110 (8), 2159-64
DOI 10.1038/bjc.2014.133, PubMed 24642618
Entropy-based adaptive nuclear texture features are independent prognostic markers in a total population of uterine sarcomas
Cytometry A, 87 (4), 315-25
DOI 10.1002/cyto.a.22601, PubMed 25483227
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
Biochem J, 461 (3), 383-90
DOI 10.1042/BJ20140132, PubMed 24840251
Publications 2013
Use of multivariate analysis to suggest a new molecular classification of colorectal cancer
J Pathol, 229 (3), 441-8
DOI 10.1002/path.4139, PubMed 23165447
Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer
Proc Natl Acad Sci U S A, 110 (28), E2572-81
DOI 10.1073/pnas.1304318110, PubMed 23798432
TCTP is an androgen-regulated gene implicated in prostate cancer
PLoS One, 8 (7), e69398
DOI 10.1371/journal.pone.0069398, PubMed 23894469
Genomic aberration patterns and expression profiles of squamous cell carcinomas of the vulva
Genes Chromosomes Cancer, 52 (6), 551-63
DOI 10.1002/gcc.22053, PubMed 23404381
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
Am J Gastroenterol, 108 (11), 1785-93
DOI 10.1038/ajg.2013.292, PubMed 24042191
Fifteen-year mortality after radical prostatectomy: which factors are available for patient counselling?
Scand J Urol, 48 (2), 123-30
DOI 10.3109/21681805.2013.817483, PubMed 23885810
Publications 2012
A camera support for operating theatre videography
J Vis Commun Med, 35 (1), 20-4
DOI 10.3109/17453054.2012.656585, PubMed 22397480
Automatic segmentation of cell nuclei in Feulgen-stained histological sections of prostate cancer and quantitative evaluation of segmentation results
Cytometry A, 81 (7), 588-601
DOI 10.1002/cyto.a.22068, PubMed 22605528
The prognostic value of adaptive nuclear texture features from patient gray level entropy matrices in early stage ovarian cancer
Anal Cell Pathol (Amst), 35 (4), 305-14
DOI 10.3233/ACP-2012-0065, PubMed 22596183
DNA ploidy may be a prognostic marker in stage I and II serous adenocarcinoma of the endometrium
Virchows Arch, 461 (3), 291-8
DOI 10.1007/s00428-012-1275-2, PubMed 22824999
Flotillins as regulators of ErbB2 levels in breast cancer
Oncogene, 32 (29), 3443-51
DOI 10.1038/onc.2012.357, PubMed 22869152
Publications 2011
Multiple chromosomal monosomies are characteristic of giant cell ependymoma
Hum Pathol, 42 (12), 2042-6
DOI 10.1016/j.humpath.2011.02.012, PubMed 21683982
Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus
Br J Cancer, 105 (8), 1218-23
DOI 10.1038/bjc.2011.353, PubMed 21934680
Genomic imbalances in endometrial adenocarcinomas - comparison of DNA ploidy, karyotyping and comparative genomic hybridization
Mol Oncol, 6 (1), 98-107
DOI 10.1016/j.molonc.2011.10.002, PubMed 22062770
Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium
Ann Oncol, 23 (5), 1178-1184
DOI 10.1093/annonc/mdr368, PubMed 21965471
Publications 2010
DNA ploidy heterogeneity in endometrial carcinoma: comparison between curettage and hysterectomy specimens
Int J Gynecol Pathol, 29 (6), 572-8
DOI 10.1097/PGP.0b013e3181e2e8ee, PubMed 20881853
STAMP1 is both a proliferative and an antiapoptotic factor in prostate cancer
Cancer Res, 70 (14), 5818-28
DOI 10.1158/0008-5472.CAN-09-4697, PubMed 20587517
Publications 2009
Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients
Histopathology, 54 (3), 355-64
DOI 10.1111/j.1365-2559.2009.03231.x, PubMed 19236512
Large-scale genomic instability in colon adenocarcinomas and correlation with patient outcome
APMIS, 117 (10), 730-6
DOI 10.1111/j.1600-0463.2009.02527.x, PubMed 19775341
Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
Neuro Oncol, 11 (5), 514-28
DOI 10.1215/15228517-2008-127, PubMed 19182148
The prognostic value of DNA ploidy in a total population of uterine sarcomas
Ann Oncol, 20 (6), 1037-41
DOI 10.1093/annonc/mdn765, PubMed 19201782
Beta-catenin expression in uterine sarcomas and its relation to clinicopathological parameters
Eur J Cancer, 45 (13), 2412-7
DOI 10.1016/j.ejca.2009.06.017, PubMed 19622417
Gross genomic alterations differ between serous borderline tumors and serous adenocarcinomas--an image cytometric DNA ploidy analysis of 307 cases with histogenetic implications
Virchows Arch, 454 (6), 677-83
DOI 10.1007/s00428-009-0778-y, PubMed 19421773
Large scale genomic instability as an additive prognostic marker in early prostate cancer
Cell Oncol, 31 (4), 251-9
DOI 10.3233/CLO-2009-0463, PubMed 19633362
Publications 2008
The mitogen-activated protein kinase phosphatase vaccinia H1-related protein inhibits apoptosis in prostate cancer cells and is overexpressed in prostate cancer
Cancer Res, 68 (22), 9255-64
DOI 10.1158/0008-5472.CAN-08-1224, PubMed 19010898
Consistent numerical chromosome aberrations in thecofibromas of the ovary
Virchows Arch, 452 (3), 269-76
DOI 10.1007/s00428-007-0561-x, PubMed 18188592
Statistical nuclear texture analysis in cancer research: a review of methods and applications
Crit Rev Oncog, 14 (2-3), 89-164
DOI 10.1615/critrevoncog.v14.i2-3.10, PubMed 19409060
Publications 2007
Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer
Cancer Res, 67 (11), 5221-30
DOI 10.1158/0008-5472.CAN-06-4728, PubMed 17545602
A distinct pattern in the DNA ploidy histograms of hydatidiform moles and nonmolar abortuses is caused by accumulation of trophoblasts in the late s-phase
Int J Gynecol Pathol, 26 (4), 432-6
DOI 10.1097/pgp.0b013e31803c7c2e, PubMed 17885494
Abnormal DNA content predicts the occurrence of carcinomas in non-dysplastic oral white patches (Retraction of vol 37, pg 558, 2001)
Oral Oncol., 43 (4), 418
DOI 10.1016/j.oraloncology.2007.01.001
Publications 2006
Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas
Mod Pathol, 19 (2), 186-94
DOI 10.1038/modpathol.3800499, PubMed 16258504
Prognostic value of adaptive textural features--the effect of standardizing nuclear first-order gray level statistics and mixing information from nuclei having different area
Cell Oncol, 28 (3), 85-95
DOI 10.1155/2006/370173, PubMed 16823177
Prognostic value of adaptive textural features - The effect of standardizing nuclear first-order gray level statistics and mixing information from nuclei having different area
Cell. Oncol., 28 (3), 85-95
Image cytometry DNA ploidy correlates with histological subtypes in endometrial carcinomas
Mod Pathol, 19 (9), 1227-35
DOI 10.1038/modpathol.3800641, PubMed 16729014
Publications 2005
Chromosome 7 abnormalities are common in chordomas
Cancer Genet Cytogenet, 160 (1), 15-21
DOI 10.1016/j.cancergencyto.2004.11.016, PubMed 15949565
Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
J Pathol, 206 (3), 305-11
DOI 10.1002/path.1772, PubMed 15852498
Prognostic factors in ovarian carcinoma stage III patients. Can biomarkers improve the prediction of short- and long-term survivors?
Int J Gynecol Cancer, 15 (6), 1014-22
DOI 10.1111/j.1525-1438.2005.00185.x, PubMed 16343177
beta-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: a study in 253 patients
Eur J Cancer, 41 (8), 1127-34
DOI 10.1016/j.ejca.2005.01.022, PubMed 15911235
Volume-related sequence of tumor distribution pattern in prostate carcinoma: importance of posterior midline crossover in predicting tumor volume, extracapsular extension, and seminal vesicle invasion
Croat Med J, 46 (3), 429-35
PubMed 15861523
Publications 2004
Pilomatrix carcinoma with lymph node metastases
J Cutan Pathol, 31 (4), 330-5
DOI 10.1111/j.0303-6987.2004.0178.x, PubMed 15005691
Evaluation of genomic changes in a large series of malignant ovarian germ cell tumors--relation to clinicopathologic variables
Cancer Genet Cytogenet, 155 (1), 25-32
DOI 10.1016/j.cancergencyto.2004.02.010, PubMed 15527899
Analysis of androgen regulated homeobox gene NKX3.1 during prostate carcinogenesis
J Urol, 172 (3), 1134-9
DOI 10.1097/01.ju.0000136526.78535.b8, PubMed 15311057
Low dimensional adaptive texture feature vectors from class distance and class difference matrices
IEEE Trans Med Imaging, 23 (1), 73-84
DOI 10.1109/TMI.2003.819923, PubMed 14719689
TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
Br J Cancer, 90 (3), 678-85
DOI 10.1038/sj.bjc.6601537, PubMed 14760384
Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer
Cancer Res, 64 (7), 2365-70
DOI 10.1158/0008-5472.can-03-2025, PubMed 15059887
Publications 2003
Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
Hum Pathol, 34 (9), 946-9
DOI 10.1016/s0046-8177(03)00345-9, PubMed 14562293
Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer
Ann Oncol, 14 (10), 1494-500
DOI 10.1093/annonc/mdg403, PubMed 14504048
Publications 2002
Gross genomic aberrations in precancers: clinical implications of a long-term follow-up study in oral erythroplakias
J Clin Oncol, 20 (2), 456-62
DOI 10.1200/JCO.2002.20.2.456, PubMed 11786574
Publications 2001
Fourth updated ESACP consensus report on diagnostic DNA image cytometry
Anal Cell Pathol, 23 (2), 89-95
DOI 10.1155/2001/657642, PubMed 11904464
Prognostic classification of early ovarian cancer based on very low dimensionality adaptive texture feature vectors from cell nuclei from monolayers and histological sections
Anal Cell Pathol, 23 (2), 75-88
DOI 10.1155/2001/683747, PubMed 11904463
A socket interface for GALS using locally dynamic voltage scaling for rate-adaptive energy saving
P IEEE INT ASIC C&E, 110-116
DOI 10.1109/ASIC.2001.954682
Serum hepatocyte growth factor levels in patients with chronic renal disease--effect of GFR and pathogenesis
Scand J Clin Lab Invest, 61 (8), 615-9
DOI 10.1080/003655101753267973, PubMed 11768321
Cystatin C levels in sera of patients with acute infectious diseases with high C-reactive protein levels
Scand J Clin Lab Invest, 61 (4), 333-5
DOI 10.1080/00365510152379076, PubMed 11465348
TP53 and p21WAF1/CIP1 behave differently in euploid versus aneuploid bladder tumours treated with radiotherapy
Acta Oncol, 40 (5), 644-52
DOI 10.1080/028418601750444213, PubMed 11669339
Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence
Neoplasia, 3 (3), 196-203
DOI 10.1038/sj.neo.7900153, PubMed 11494113
Comparison of histological grading and large-scale genomic status (DNA ploidy) as prognostic tools in oral dysplasia
J Pathol, 194 (3), 303-10 (Retracted)
DOI 10.1002/1096-9896(200107)194:3<303::AID-PATH879>3.0.CO;2-Q, PubMed 11439362
DNA content as a prognostic marker in patients with oral leukoplakia
N Engl J Med, 344 (17), 1270-8 (Retracted)
DOI 10.1056/NEJM200104263441702, PubMed 11320386
Abnormal DNA content predicts the occurrence of carcinomas in non-dysplastic oral white patches
Oral Oncol, 37 (7), 558-65 (Retracted)
DOI 10.1016/s1368-8375(00)00126-3, PubMed 11564576
Publications 2000
Adaptive gray level run length features from class distance matrices
In Proceedings: en samling artikler og sammendrag fra NOBIM konferansen 2000, Statoil, Trondheim 6. og 7. juni 2000, NOBIM 2000-sekretariatet, Ås, S. 75-78
BIBSYS 02000477x
Duedtie: sør-samisk håndverk
In Fjell-folk: årbok for Rørosmuseet, Museet, Røros, S. 45-46
BIBSYS 111153409
[Digital image analysis in pathology--exemplified in prostatic cancer]
Tidsskr Nor Laegeforen, 120 (4), 479-88
PubMed 10833941
[Telepathology at the Norwegian Radium Hospital]
Tidsskr Nor Laegeforen, 120 (18), 2170-3
PubMed 11006741
Serum cystatin C as an endogenous parameter of the renal function in patients with normal to moderately impaired kidney function
Clin Nephrol, 54 (3), 203-9
PubMed 11020018
Publications 1999
[Telepathology in Norway]
Tidsskr Nor Laegeforen, 119 (9), 1335
PubMed 10327860
A prospective, randomized multicenter study comparing APD and CAPD treatment
Perit Dial Int, 19 (6), 526-33
PubMed 10641772
Airborne allergic contact dermatitis from colophony in a car
Contact Dermatitis, 41 (1), 51
DOI 10.1111/j.1600-0536.1999.tb06216.x, PubMed 10416717
The use of fractal features from the periphery of cell nuclei as a classification tool
Anal Cell Pathol, 19 (1), 21-37
DOI 10.1155/1999/986086, PubMed 10661622
Reference interval for serum cystatin C in children
Clin Chem, 45 (10), 1856-8
PubMed 10508134
Publications 1998
Registration of serial sections of mouse liver cell nuclei
J Microsc, 192 (Pt 1), 37-53
DOI 10.1046/j.1365-2818.1998.00405.x, PubMed 9848269
Synovial sarcoma. Evaluation of prognosis with emphasis on the study of DNA ploidy and proliferation (PCNA and Ki-67) markers
Anal Cell Pathol, 16 (1), 45-62
DOI 10.1155/1998/545906, PubMed 9584899
Atraumatic loss of a kidney in a patient with alpha1-antitrypsin deficiency
Nephron, 80 (1), 71-5
DOI 10.1159/000045130, PubMed 9730708
Serum cystatin C as a marker of the renal function
Scand J Clin Lab Invest, 58 (7), 585-92
DOI 10.1080/00365519850186210, PubMed 9890342
A review of caveats in statistical nuclear image analysis
Anal Cell Pathol, 16 (2), 63-82
DOI 10.1155/1998/436382, PubMed 9692681
Ultrastructural texture analysis as a diagnostic tool in mouse liver carcinogenesis
Ultrastruct Pathol, 22 (1), 27-37
DOI 10.3109/01913129809032255, PubMed 9491213
Publications 1997
[Telemedicine--cost and benefit]
Tidsskr Nor Laegeforen, 117 (11), 1582-3
PubMed 9198937
Uremia and HbA1c
Diabetes Care, 20 (8), 1341-2
DOI 10.2337/diacare.20.8.1341b, PubMed 9250470
Prognostic factors in patients with metastatic (stage D2) prostate cancer: experience from the Scandinavian Prostatic Cancer Group Study-2
J Urol, 158 (1), 164-70
DOI 10.1097/00005392-199707000-00052, PubMed 9186346
Publications 1996
Nuclear texture analysis: a new prognostic tool in metastatic prostate cancer
Cytometry, 24 (3), 277-83
DOI 10.1002/(SICI)1097-0320(19960701)24:3<277::AID-CYTO11>3.0.CO;2-N, PubMed 8800561
Enhanced antitumour effect of photodynamic therapy by microtubule inhibitors
Cancer Lett, 109 (1-2), 129-39
DOI 10.1016/s0304-3835(96)04437-0, PubMed 9020912
Entropy-based texture analysis of chromatin structure in advanced prostate cancer
Cytometry, 24 (3), 268-76
DOI 10.1002/(SICI)1097-0320(19960701)24:3<268::AID-CYTO10>3.0.CO;2-O, PubMed 8800560
Publications 1995
DNA ploidy, serum prostate specific antigen, histological grade and immunohistochemistry as predictive parameters of lymph node metastases in T1-T3/M0 prostatic adenocarcinoma
Br J Urol, 75 (1), 26-32
DOI 10.1111/j.1464-410x.1995.tb07227.x, PubMed 7531589
Up-regulation of the oligosaccharide sialyl LewisX: a new prognostic parameter in metastatic prostate cancer
Cancer Res, 55 (9), 1817-9
PubMed 7728744
Extent of disease based on initial bone scan: important prognostic predictor for patients with metastatic prostatic cancer. Experience from the Scandinavian Prostatic Cancer Group Study No. 2 (SPCG-2)
Eur Urol, 28 (1), 40-6
DOI 10.1159/000475018, PubMed 8521893
Histopathological grading and DNA ploidy as prognostic markers in metastatic prostatic cancer
Br J Cancer, 71 (5), 1055-60
DOI 10.1038/bjc.1995.203, PubMed 7734299
Publications 1994
Intravenous iron-sucrose complex to reduce epoetin demand in dialysis patients
Lancet, 344 (8932), 1305-6
DOI 10.1016/s0140-6736(94)90797-8, PubMed 7968018
Caveats in the use of archival cell material for DNA ploidy analysis by image cytometry
Anal Cell Pathol, 7 (3), 217-33
PubMed 7531484
Publications 1993
Caveats in the estimation of DNA-ploidy in paraffin embedded specimens of primary prostate cancer and lymph node metastases by flow and image cytometry
Anal Cell Pathol, 5 (6), 339-52
PubMed 8305330
DNA distribution in the prostate. Normal gland, benign and premalignant lesions, and subsequent adenocarcinomas
Anal Quant Cytol Histol, 15 (4), 247-52
PubMed 7691062
Unchanged noradrenaline reactivity and blood pressure after corrective surgery in primary hyperparathyroidism
Scand J Clin Lab Invest, 53 (5), 479-86
DOI 10.1080/00365519309092543, PubMed 8210970
Genetic alterations in a malignant schwannoma from a patient with neurofibromatosis (NF1)
Pathol Res Pract, 189 (4), 465-71; discussion 471-4
DOI 10.1016/S0344-0338(11)80339-0, PubMed 8351250
Effect of captopril on renal extraction of renin, angiotensin II, atrial natriuretic peptide and vasopressin, and renal vein renin ratio in patients with arterial hypertension and unilateral renal artery disease
Nephrol Dial Transplant, 8 (10), 1064-70
PubMed 8272217
CMOS DRIVER FOR 50-OMEGA LOAD
Electron. Lett., 29 (10), 876-878
DOI 10.1049/el:19930585
Publications 1992
Glomerular and tubular antinatriuretic actions of low-dose angiotensin II infusion in man
J Hypertens, 10 (9), 1033-40
PubMed 1328362
Analytical methods for the study of liver cell proliferation
Cytometry, 13 (4), 404-15
DOI 10.1002/cyto.990130411, PubMed 1382009
Comparison between flow cytometry and image cytometry in ploidy distribution assessments in gynecologic cancer
Cytometry, 13 (3), 314-21
DOI 10.1002/cyto.990130314, PubMed 1576895
Molecular genetic studies of tumor suppressor gene regions on chromosomes 13 and 17 in colorectal tumors
J Natl Cancer Inst, 84 (14), 1100-8
DOI 10.1093/jnci/84.14.1100, PubMed 1619684
Publications 1991
Premalignant changes in DNA organization in mouse liver after diethylnitrosamine treatment
The Norwegian Radium Hospital and Institute for Cancer Research : The Norwegian Cancer Society, Oslo, 1 b. (flere pag.)
BIBSYS 921057067, ISBN 82-7633-016-9
Specific gain of chromosome 19 in preneoplastic mouse liver cells after diethylnitrosamine treatment
Carcinogenesis, 12 (10), 1777-80
DOI 10.1093/carcin/12.10.1777, PubMed 1934257
Attenuated renal excretory response to atrial natriuretic peptide in congestive heart failure in man
Int J Cardiol, 33 (1), 61-74
DOI 10.1016/0167-5273(91)90153-g, PubMed 1657800
Subcellular localization, redistribution and photobleaching of sulfonated aluminum phthalocyanines in a human melanoma cell line
Int J Cancer, 49 (2), 290-5
DOI 10.1002/ijc.2910490225, PubMed 1879972
Localization of potent photosensitizers in human tumor LOX by means of laser scanning microscopy
Cancer Lett, 58 (1-2), 17-27
DOI 10.1016/0304-3835(91)90019-e, PubMed 1828711
Location of P-II and AlPCS4 in human tumor LOX in vitro and in vivo by means of computer-enhanced video fluorescence microscopy
Cancer Lett, 58 (1-2), 37-47
DOI 10.1016/0304-3835(91)90021-9, PubMed 1828713
Publications 1990
Atrial natriuretic peptide and blood volume in patients with chronic glomerulonephritis: effects of albumin and frusemide administration
Nephrol Dial Transplant, 5 (12), 997-1006
DOI 10.1093/ndt/5.12.997, PubMed 1965738
Localization of potent photosensitizers in human tumor LOX by means of laser scanning microscopy
Cancer Lett, 53 (2-3), 129-39
DOI 10.1016/0304-3835(90)90205-c, PubMed 2208072
Publications 1989
Characterization of chromatin structure by image analysis--a method for the assessment of changes in chromatin organization
Scanning Microsc Suppl, 3, 297-302
PubMed 2616956
Elevated angiotensin II and vasopressin in primary hyperparathyroidism. Angiotensin II infusion studies before and after removal of the parathyroid adenoma
Acta Endocrinol (Copenh), 120 (3), 362-8
DOI 10.1530/acta.0.1200362, PubMed 2522705
Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method
Eur J Clin Invest, 19 (2), 135-41
DOI 10.1111/j.1365-2362.1989.tb00207.x, PubMed 2499471
Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension
J Hypertens, 7 (1), 21-9
DOI 10.1097/00004872-198901000-00004, PubMed 2523419
Publications 1988
Atrial natriuretic peptide, angiotensin II and aldosterone in plasma in chronic glomerulonephritis during basal conditions and during exercise
Acta Med Scand, 224 (1), 61-7
DOI 10.1111/j.0954-6820.1988.tb16739.x, PubMed 2970768
Ploidy distribution in experimental liver carcinogenesis in mice
Carcinogenesis, 9 (1), 59-63
DOI 10.1093/carcin/9.1.59, PubMed 3335048
Reduced angiotensin II induced vascular reactivity in chronic renal failure
Scand J Clin Lab Invest, 48 (7), 705-13
PubMed 3201105
Urinary prostaglandin E2 and F2 alpha excretion in nephrotic syndrome during basal conditions, after water loading, and after remission of the syndrome
Acta Med Scand, 224 (1), 69-77
DOI 10.1111/j.0954-6820.1988.tb16740.x, PubMed 3166326
Increased atrial natriuretic peptide in the nephrotic syndrome. Relationship to the renal function and the renin-angiotensin-aldosterone system
Scand J Clin Lab Invest, 48 (2), 141-7
DOI 10.3109/00365518809085406, PubMed 2965826
Acute and long-term renal effects of angiotensin converting enzyme inhibition in normotensive, normoalbuminuric insulin-dependent diabetic patients
Diabet Med, 5 (6), 562-9
DOI 10.1111/j.1464-5491.1988.tb01052.x, PubMed 2850132
Increased atrial natriuretic peptide in an early stage of chronic glomerulonephritis
Scand J Clin Lab Invest, 48 (4), 347-55
DOI 10.3109/00365518809167507, PubMed 2976977
MONOSIZED MAGNETIC PARTICLES AND THEIR USE IN SELECTIVE CELL-SEPARATION
MAKROMOL CHEM-M SYMP, 17, 177-211
DOI 10.1002/masy.19880170113
Publications 1987
Effect of chronic hypokalaemia on renal concentrating ability and secretion of arginine vasopressin
Scand J Clin Lab Invest, 47 (1), 5-9
PubMed 3576109
Exaggerated natriuretic response to isotonic volume expansion in hypertensive renal transplant recipients: evaluation of proximal and distal tubular reabsorption by simultaneous determination of renal plasma clearance of lithium and 51Cr-EDTA
Eur J Clin Invest, 17 (1), 37-42
DOI 10.1111/j.1365-2362.1987.tb01223.x, PubMed 3106049
Relationship between urinary prostaglandin E2 and F2 alpha excretion and plasma arginine vasopressin during renal concentrating and diluting tests in renal transplant recipients
Eur J Clin Invest, 17 (5), 429-34
DOI 10.1111/j.1365-2362.1987.tb01138.x, PubMed 3121347
Renal plasma flow and glomerular filtration rate during antihypertensive therapy in essential hypertension
Dan Med Bull, 34 Suppl 1, 7-8
PubMed 3436171
USE METHANE FOR DENSITY-METER CALIBRATION
Oil Gas J., 85 (8), 61-&
Publications 1986
The interaction between cell-surface antigens and antibodies bound to monodisperse polymer particles in normal and malignant cells
Scand J Immunol, 24 (2), 179-87
DOI 10.1111/j.1365-3083.1986.tb02084.x, PubMed 3749814
Direct preparation and G-banding of chromosomes of mouse liver cells
Mutat Res, 164 (3), 177-81
DOI 10.1016/0165-1161(86)90008-7, PubMed 3713719
A method for determining ploidy distributions in liver tissue by stereological analysis of nuclear size calibrated by flow cytometric DNA analysis
Cytometry, 7 (5), 475-80
DOI 10.1002/cyto.990070514, PubMed 3757695
Exaggerated natriuresis in adult polycystic kidney disease
Acta Med Scand, 219 (1), 59-66
DOI 10.1111/j.0954-6820.1986.tb03276.x, PubMed 3953317
Relationship of angiotensin II, aldosterone, arginine vasopressin, adrenaline and noradrenaline in plasma, blood and extracellular volumes to blood pressure in chronic glomerulonephritis
Eur J Clin Invest, 16 (1), 85-90
DOI 10.1111/j.1365-2362.1986.tb01312.x, PubMed 3084277
Expansion of extracellular volume in early polycystic kidney disease
Acta Med Scand, 219 (4), 399-405
DOI 10.1111/j.0954-6820.1986.tb03330.x, PubMed 3716882
[Primary hyperaldosteronism caused by bilateral suprarenal cortical hyperplasia. Diagnostic and therapeutic aspects]
Ugeskr Laeger, 148 (13), 770-1
PubMed 3705213
Urinary excretion of albumin and beta-2-microglobulin in hypertensive and normotensive renal transplant recipients during urinary diluting and concentrating tests
Scand J Clin Lab Invest, 46 (7), 609-14
DOI 10.3109/00365518609083721, PubMed 3538362
Impaired renal water excretion in early hepatic cirrhosis. Lack of relationship between renal water excretion and plasma levels of arginine vasopressin, angiotensin II, and aldosterone after water loading
Scand J Gastroenterol, 21 (6), 749-55
DOI 10.3109/00365528609011112, PubMed 3749808
Renovascular hypertension. Ability to renal vein ratio to predict the blood pressure level 18-24 months after surgery
Nephron, 44 Suppl 1, 29-31
DOI 10.1159/000184042, PubMed 3528884
Angiotensin II, aldosterone and arginine vasopressin in plasma in congestive heart failure
Eur J Clin Invest, 16 (1), 56-60
DOI 10.1111/j.1365-2362.1986.tb01308.x, PubMed 3084274
Post-renal-transplant hypertension. Urine volume, free water clearance and plasma concentrations of arginine vasopressin, angiotensin II and aldosterone before and after oral water loading in hypertensive and normotensive renal transplant recipients
Scand J Clin Lab Invest, 46 (5), 451-8
DOI 10.3109/00365518609083697, PubMed 3529350
Abnormal vasopressin and aldosterone response to furosemide in essential hypertension
Acta Med Scand, 219 (4), 387-92
DOI 10.1111/j.0954-6820.1986.tb03328.x, PubMed 3716880
Effect of exercise on plasma concentrations of arginine vasopressin, angiotensin II and aldosterone in hypertensive and normotensive renal transplant recipients
Scand J Clin Lab Invest, 46 (2), 151-7
DOI 10.3109/00365518609083651, PubMed 3520789
Experience with percutaneous transluminal renal angioplasty in renovascular hypertension
Acta Med Scand Suppl, 714, 23-7
DOI 10.1111/j.0954-6820.1986.tb08963.x, PubMed 2953176
Hypotension in end-stage renal disease: effect of postural change, exercise and angiotensin II infusion on blood pressure and plasma concentrations of angiotensin II, aldosterone and arginine vasopressin in hypotensive patients with chronic renal failure treated by dialysis
Clin Nephrol, 26 (6), 288-96
PubMed 3802595
Effect of captopril on renal haemodynamics and the renin-angiotensin-aldosterone and osmoregulatory systems in essential hypertension
Eur J Clin Pharmacol, 30 (1), 1-6
DOI 10.1007/BF00614186, PubMed 3519238
Morphological and functional characteristics of isolated resistance vessels in advanced uraemia
Clin Sci (Lond), 71 (6), 657-63
DOI 10.1042/cs0710657, PubMed 3791868
Publications 1985
Angiotensin II, aldosterone and arginine-vasopressin in exaggerated natriuresis of chronic glomerulonephritis
Acta Med Scand Suppl, 693, 77-80
DOI 10.1111/j.0954-6820.1985.tb08781.x, PubMed 3857849
Abnormal renal sodium excretion in the nephrotic syndrome after furosemide: relation to glomerular filtration rate
Acta Med Scand, 217 (5), 513-8
DOI 10.1111/j.0954-6820.1985.tb03255.x, PubMed 4025007
Arginine vasopressin and cyclic adenosine monophosphate during acute sodium loading in chronic glomerulonephritis
Scand J Clin Lab Invest, 45 (3), 199-205
DOI 10.3109/00365518509160996, PubMed 2988106
[Hypokalemic paresis and myopathy after consumption of a bitter brandy. Licorice-induced pseudo-hyperaldosteronism]
Ugeskr Laeger, 147 (35), 2765-7
PubMed 4071716
Defective renal water excretion in nephrotic syndrome: the relationship between renal water excretion and kidney function, arginine vasopressin, angiotensin II and aldosterone in plasma before and after oral water loading
Eur J Clin Invest, 15 (1), 24-9
DOI 10.1111/j.1365-2362.1985.tb00139.x, PubMed 3921381
Relationship between urinary concentrating ability, arginine vasopressin in plasma and blood pressure after renal transplantation
Scand J Clin Lab Invest, 45 (4), 321-6
DOI 10.3109/00365518509161014, PubMed 3892648
The osmoregulatory system and the renin-angiotensin-aldosterone system in pre-eclampsia and normotensive pregnancy
Scand J Clin Lab Invest, 45 (7), 627-33
DOI 10.3109/00365518509155270, PubMed 4070961
Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension
Eur J Clin Pharmacol, 29 (3), 257-61
DOI 10.1007/BF00544077, PubMed 4076325
Abnormal vascular function and morphology in pre-eclampsia: a study of isolated resistance vessels
Clin Sci (Lond), 69 (4), 477-82
DOI 10.1042/cs0690477, PubMed 4042548
Publications 1984
Serum immunoglobulin sedimentation patterns and circulating immune complexes in IgA glomerulonephritis and Schönlein-Henoch nephritis
Acta Med Scand, 215 (5), 435-41
DOI 10.1111/j.0954-6820.1984.tb17675.x, PubMed 6377828
Renin-angiotensin-aldosterone system in exaggerated natriuresis of chronic glomerulonephritis
Scand J Clin Lab Invest, 44 (8), 693-702
DOI 10.3109/00365518409083632, PubMed 6528215
Effect of indapamide on the renin-aldosterone system, and urinary excretion of potassium and calcium in essential hypertension
Br J Clin Pharmacol, 18 (2), 229-31
DOI 10.1111/j.1365-2125.1984.tb02458.x, PubMed 6386023
Solid-phase radioimmunoassay of immunoglobulins G, A and M: applicability in analysis of sucrose gradients
J Immunol Methods, 71 (2), 127-32
DOI 10.1016/0022-1759(84)90058-9, PubMed 6234366
Significance of the renin-angiotensin system for blood pressure regulation in end-stage renal disease
Contrib Nephrol, 41, 123-7
DOI 10.1159/000429274, PubMed 6098411
Effect of indapamide on renal plasma flow, glomerular filtration rate and arginine vasopressin in plasma in essential hypertension
Eur J Clin Pharmacol, 26 (5), 543-7
DOI 10.1007/BF00543482, PubMed 6468469
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy
Scand J Clin Lab Invest Suppl, 169, 48-56
DOI 10.3109/00365518409085377, PubMed 6387885
Publications 1983
Normalization of hepatic lysosomal autophagy in streptozotocin diabetic rats after pancreatic transplantation
Virchows Arch B Cell Pathol Incl Mol Pathol, 43 (2), 189-97
DOI 10.1007/BF02932956, PubMed 6137107
Arterial hypertension in chronic glomerulonephritis. An analysis of 310 cases
Clin Nephrol, 19 (6), 284-7
PubMed 6872365
Publications 1981
Bilirubin-liposome interaction. Binding of bilirubin dianion, protonization, and aggregation of bilirubin acid
J Biol Chem, 256 (9), 4269-74
PubMed 7194339