Jostein Dahle from Trond Stokke's group at the Department of Radiation Biology has become a partner in the new four-year European integrated project NOTE (Non-targeted effects of ionising radiation), which was launced by a kick-off meeting held in Espoo in Finland September 11-14. The project aims to expand the current understanding of health effects caused by low-level doses of ionising radiation.
The NOTE project brings together 19 major European and Canadian groups involved in investigaion of non-targeted effects in cellular, tissue and animal models.
The role of Jostein Dahle and co-workers is to investigate non-targeted effects of alpha particle radiation on cells in culture, approaching the subject from two angles: experiments and mathematical modeling.
Chauhan SK, Dunn C, Andresen NK, Røssevold AH, Skorstad G, Sike A, Gilje B, Raj SX, Huse K, Naume B, Kyte JA(2024) Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation NPJ Breast Cancer, 10(1), 30 DOI 10.1038/s41523-024-00638-2, PubMed 38653982
Miceli R, Eriksson H, Lo Russo G, Alfieri S, Moksnes Bjaanæs M, Pietrantonio F, De Cecco L, Prelaj A, Proto C, Franzén J, McDonnell D, Berenguer Pina JJ, Beninato T, Mazzeo L, Giannatempo P, Verzoni E, Crown J, Helland Å, Eustace A(2024) Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study Acta Oncol, 63, 213-219 DOI 10.2340/1651-226X.2024.24179, PubMed 38647024
Fackler MJ, Pleas M, Li Y, Soni A, Xing D, Cope L, Ali S, Van Le Q, Van Nguyen C, Pham HT, Duong LM, Vanden Berg E, Wadee R, Michelow P, Chen WC, Joffe M, Fjeldbo CS, Lyng H, Sukumar S(2024) Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries Clin Epigenetics, 16(1), 56 DOI 10.1186/s13148-024-01669-z, PubMed 38643219