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Infections and inflammation in urology

The group’s research activity mainly focuses on inflammation and infections in the urinary tracts, and for better and more accurate treatment that prevents antibiotic resistance.

The Groups Research Profile

  • Asymptomatic bacteriuria

  • Antimicrobial resistance, mathematical modelling of development of resistance

  • Antibiotic stewardship

  • Infection prophylaxis

  • Infectious  complications in urology

  • Classification of urinary tract infections

  • Microbiome in urine

  • Phage therapy in prophylaxis and treatment

  • Tuberculosis in the urinary tract

  • Urosepsis

Long Term Goals

The Group's goal is to record the incidence of urinary tract infections, types of microorganisms, antibiotic resistance and risk factors in order to improve the use of antibiotics and non-antibiotic preparations (antibiotic stewardship).

The recording will contribute to both the prevention and treatment of the individual patient and predict the development of antibiotic resistance in an international perspective. Thereby reducing the morbidity associated with urinary tract infections.

Projects

The group's members are involved in the following Projects:

  1. Global Prevalence Study of Infections in Urology (GPIU annual)

  2. Global Prevalence Study of Infections after Prostate biopsy (GPIU biopsy)

  3. Global Prevalence Study of Infections in community (GPIU com)

  4. Longitudinal Study on Urosepsis (Serpens)

  5. EU COST project on urinary stents

  6. Scientific Network to Tackle Antimicrobial Resistance In Infections (SENTRII Application 2019)

  7. Norwegian study on antibiotic prophylaxis in prostate biopsy

Cooperation

The group is collaborating with the European Section of Infections in Urology / European Association of Urology. The GPIU studies are conducted in more than one hundred countries, and the SENTRII project is supported by researchers in more than 30 countries.

Selected Publications

Living textbook: Urogenital Infections and Inflammations. T.E. Bjerklund Johansen, F. M.E. Wagenlehner, Y.-H. Cho, T. Matsumoto, J. N. Krieger, D. Shoskes, K. Naber
https://books.publisso.de/en/publisso_gold/publishing/books/overview/52
XYLOGLUCAN, HIBISCUS AND PROPOLIS TO REDUCE SYMPTOMS AND ANTIBIOTICS USE IN RECURRENT UTIS: A PROSPECTIVE STUDY.  
Tommaso Cai, Irene Tamanini, Andrea Cocci, Fabrizio Di Maida, Patrizio Caciagli, Serena Migno, Liliana Mereu, Saverio Tateo, Gianni Malossini, Alessandro Palmieri, Paolo Verze, Vincenzo Mirone, Truls E. Bjerklund Johansen, 2019, bind 14, nummer 12, s. 1013-1021. Future Microbiology Link to publication in Scopus. DOI

CURRENT KNOWLEDGE OF THE POTENTIAL LINKS BETWEEN INFLAMMATION AND PROSTATE CANCER
Tommaso Cai, Raffaella Santi, Irene Tamanini, Ilaria Camilla Galli, Gianpaolo Perletti, Truls E. Bjerklund Johansen, Gabriella Nesi, 2019, bind 20, nummer 15. International Journal of Molecular Sciences Link to publication in Scopus. DOI.

APPROPRIATE EMPIRIC ANTIBIOTIC CHOICES IN HEALTH CARE ASSOCIATED URINARY TRACT INFECTIONS IN UROLOGY DEPARTMENTS IN EUROPE FROM 2006 TO 2015: A BAYESIAN ANALYTICAL APPROACH APPLIED IN A SURVEILLANCE STUDY
Zafer Tandogdu, Evgenios T.A. Kakariadis, Kurt Naber, Florian Wagenlehner, Truls Erik Bjerklund Johansen, 2019, bind 14, nummer 4. PLoS ONE Link to publication in Scopus. DOI.

INFECTIOUS COMPLICATIONS AFTER LASER VAPORIZATION OF URINARY STONES DURING RETROGRADE INTRARENAL SURGERY ARE NOT ASSOCIATED WITH SPREADING OF BACTERIA INTO IRRIGATION FLUID BUT WITH PREVIOUS USE OF FLUOROQUINOLONES
Tommaso Cai, Andrea Cocci, Franco Coccarelli, Lorenzo Ruggera, Paolo Lanzafame, Patrizio Caciagli, Gianni Malossini, Alfonso Crisci, Alberto Trinchieri, Giampaolo Perletti, Marco Carini, Gernot Bonkat, Riccardo Bartoletti, Truls E. Bjerklund Johansen, 2019. European Urology Focus Link to publication in Scopus. DOI.

Metagenomics in diagnosis and improved targeted treatment of UTI. Matthew Dixon, Maria Stefil, Michael McDonald, Truls Erik Bjerklund Johansen, Kurt Naber, Florian Wagenlehner, Vladimir Mouraviev. World Journal of Urology 2019: https://doi.org/10.1007/s00345-019-02731-9. 

Epidemiology of Extrapulmonary Tuberculosis. Ekaterina Kulchavenya, Kurt G. Naber and Truls Erik Bjerklund Johansen.. In Sener A, Erdem H. eds.Extrapulomonary Tuberculosis. Springer Nature Switzerland AG 2019; https://doi.oeg/10.1007/978-3-030-04744-3. Chapter1:1-14.

Urogenital Tuberculosis. Ekaterina Kulchavenya, Kurt G. Naber and Truls Erik Bjerklund Johansen. In Sener A, Erdem H. eds.Extrapulomonary Tuberculosis.Springer Nature Switzerland AG 2019; https://doi.oeg/10.1007/978-3-030-04744-3. Chapter11:141-154.

Transurethral Resection of the Prostate: are We Following the Guidelines? Outcomes from the Global Prevalence of Infections in Urology (GPIU) Study.  Bela Köves, Peter Tenke, Zafer Tandogdu, Tommaso Cai, Florian Bogenhard, Björn Wullt, Kurt Naber, Riccardo Bartoletti, Mete Cek, Ekaterina Kulchavenya, Tamara Perepanova, Adrian Pilatz, Gernot Bonkat, Truls Erik Bjerklund Johansen & Florian Wagenlehner (contributed equally as senior authors). Journal of Chemotherapy. 2019:31(1);15-22, DOI: 10.1080/1120009X.2018.1542552

Individual, DNA-guided, antibacterial prophylaxis prior to transrectal prostate biopsy based on results of next generation sequencing (NGS) of rectal swabs can be considered as a promising targeted approach to prevent severe urinary tract infection. Vladimir Mouraviev, M. Dixon, Maria Stefil, C. Skinner, M. Mcdonald, S. Vourganti, D. Albala, F. Wagenlehner, Kurt Naber, Truls E Bjerklund Johansen. E. Crawford. European Urology Supplements 18(1):e54. DOI: 10.1016/S1569-9056(19)30039-9.
Prostate – Inflammation. Mark J. Salji, Truls E. Bjerklund Johansen, Hing Y. Leung. Chapter 26: 523-30. In Aboumarzouk O. ed.: BLANDY’S UROLOGY 3rd edition. John Wiley & Sons Inc. February 2019. Item Number (DPCI): 248-91-1224 DOI: 10.1002/9781118863343.
 

 

Published Mar. 21, 2019 11:58 AM - Last modified May 12, 2020 12:40 PM

Contact

Participants

  • Truls E. Bjerklund Johansen
  • Bela Koves
  • Eduard Baco
  • Florian Wagenlhener
  • Jackhongir Alidjanov
  • Knut Kvernebo
  • Kristin Rennesund
  • Maciej Jacewicz
  • Per-Henrik Zahl
  • Tommaso Cai
  • Zafer Tandogdu
Detailed list of participants

 

 
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