Bastian Fromm

  • Post-Doc PhD
  • +47 94 12 29 55 /+47 22 78 18 73

The center of my research is the evolution of microRNAs, their function and roles in disease such as cancer, host-parasite interactions and the corresponding molecular basis of changes in their expression. I am Molecular Biologist by training and use bioinformatics methods for genome-wide miRNA complement analyses. In my current project, I study microRNAs in primary and metastatic colorectal cancer, a leading cause of cancer related deaths worldwide. I am experienced in working with NGS data and the annotation of novel miRNAs (MirGeneDB.org). I supervise students and have a considerable teaching and publication record.

 

Publications 2018

Halushka MK, Fromm B, Peterson KJ, McCall MN (2018)
Big Strides in Cellular MicroRNA Expression
Trends Genet, 34 (3), 165-167
PubMed 29361313

Tarver JE, Taylor RS, Puttick MN, Lloyd GT, Pett W, Fromm B, Schirrmeister BE, Pisani D, Peterson KJ, Donoghue PCJ (2018)
Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss
Genome Biol Evol, 10 (6), 1457-1470
PubMed 29788279

Publications 2017

Egger B, Bachmann L, Fromm B (2017)
Atp8 is in the ground pattern of flatworm mitochondrial genomes
BMC Genomics, 18 (1), 414
PubMed 28549457

Graudenzi A, Cava C, Bertoli G, Fromm B, Flatmark K, Mauri G, Castiglioni I (2017)
Pathway-based classification of breast cancer subtypes
Front Biosci (Landmark Ed), 22, 1697-1712
PubMed 28410140

Ovchinnikov VY, Mordvinov VA, Fromm B (2017)
Extreme conservation of miRNA complements in opisthorchiids
Parasitol Int, 66 (6), 773-776
PubMed 28916307

Rodríguez M, Bajo-Santos C, Hessvik NP, Lorenz S, Fromm B, Berge V, Sandvig K, Linē A, Llorente A (2017)
Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes
Mol Cancer, 16 (1), 156
PubMed 28982366

Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
Gigascience, 6 (7), 1-12
PubMed 28459977

Umu SU, Langseth H, Bucher-Johannessen C, Fromm B, Keller A, Meese E, Lauritzen M, Leithaug M, Lyle R, Rounge TB (2017)
A comprehensive profile of circulating RNAs in human serum
RNA Biol, 15 (2), 242-250
PubMed 29219730

Publications 2016

Bachmann L, Fromm B, Patella de Azambuja L, Boeger WA (2016)
The mitochondrial genome of the egg-laying flatworm Aglaiogyrodactylus forficulatus (Platyhelminthes: Monogenoidea)
Parasit Vectors, 9 (1), 285
PubMed 27188228

Flatmark K, Høye E, Fromm B (2016)
microRNAs as cancer biomarkers
Scand J Clin Lab Invest Suppl, 245, S80-3
PubMed 27542003

Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
Subtype-specific micro-RNA expression signatures in breast cancer progression
Int J Cancer, 139 (5), 1117-28
PubMed 27082076

Ramalho-Carvalho J, Fromm B, Henrique R, Jerónimo C (2016)
Deciphering the function of non-coding RNAs in prostate cancer
Cancer Metastasis Rev, 35 (2), 235-62
PubMed 27221068

Ylla G, Fromm B, Piulachs MD, Belles X (2016)
The microRNA toolkit of insects
Sci Rep, 6, 37736
PubMed 27883064

Publications 2015

Fromm B, Billipp T, Peck LE, Johansen M, Tarver JE, King BL, Newcomb JM, Sempere LF, Flatmark K, Hovig E, Peterson KJ (2015)
A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
Annu Rev Genet, 49, 213-42
PubMed 26473382

Fromm B, Trelis M, Hackenberg M, Cantalapiedra F, Bernal D, Marcilla A (2015)
The revised microRNA complement of Fasciola hepatica reveals a plethora of overlooked microRNAs and evidence for enrichment of immuno-regulatory microRNAs in extracellular vesicles
Int J Parasitol, 45 (11), 697-702
PubMed 26183562

Publications 2014

Fromm B, Burow S, Hahn C, Bachmann L (2014)
MicroRNA loci support conspecificity of Gyrodactylus salaris and Gyrodactylus thymalli (Platyhelminthes: Monogenea)
Int J Parasitol, 44 (11), 787-93
PubMed 24998346

Hahn C, Fromm B, Bachmann L (2014)
Comparative genomics of flatworms (platyhelminthes) reveals shared genomic features of ecto- and endoparastic neodermata
Genome Biol Evol, 6 (5), 1105-17
PubMed 24732282

Publications 2013

Fromm B, Worren MM, Hahn C, Hovig E, Bachmann L (2013)
Substantial loss of conserved and gain of novel MicroRNA families in flatworms
Mol Biol Evol, 30 (12), 2619-28
PubMed 24025793

Publications 2011

Fromm B, Harris PD, Bachmann L (2011)
MicroRNA preparations from individual monogenean Gyrodactylus salaris-a comparison of six commercially available totalRNA extraction kits
BMC Res Notes, 4, 217
PubMed 21714869

Publications 2009

Roth S, Fromm B, Gäde G, Predel R (2009)
A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case
BMC Evol Biol, 9, 50
PubMed 19257902

Publications 2008

Rahman MM, Fromm B, Neupert S, Kreusch S, Predel R (2008)
Extended FMRFamides in dipteran insects: conservative expression in the neuroendocrine system is accompanied by rapid sequence evolution
Gen Comp Endocrinol, 162 (1), 52-8
PubMed 18789334

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