
Hanneke FM Rhodius-Meester
- Senior consultant; MD, PhD
Hanneke Rhodius-Meester | LinkedIn
Mini CV
Education
- Specialty training in Geriatric Medicine, Amsterdam, the Netherlands (2006-2014)
- PhD Alzheimer Center, VU University, Amsterdam, ‘Optimizing use of diagnostic tests in memory clinics: the next step’ (2014-2018)
- MD, cum laude, Vrije Universiteit, Amsterdam, the Netherlands (2000-2006)
Work record
- Senior researcher Oslo Clinical Dementia Research group, OUH (2024-dd)
- Senior consultant Internal Medicine, department of geriatrics, OUH (2022-dd)
- Post-doc research Alzheimer Center Amsterdam, Amsterdam UMC (2018-2024)
- Senior consultant Internal Medicine, department of geriatrics, Amsterdam UMC (2014-2022)
Awards, committees, and memberships (selected)
- Member of the Norwegian Geriatrics Society (NGS)
- Member of the Special Interest Group Dementia related to the NGS
- ISTAART member of the Alzheimer’s Association
- ZonMW Research Fellowship, focus on future dementia diagnostics (2020-2027)
- Best postdoctoral poster competition award, AAIC 2023 Amsterdam (2023)
- Finalist Young Outstanding Research Talent award, Alzheimer Nederland (2021)
- Selected for Dutch Cardiovascular Alliance (DCVA) leadership program;- intensive training program during two years (2019-2020)
Other
- Vice-coordinator course AP5 ‘Getting older’ Bachelor Faculty of Medicine, Vrije Universiteit, Amsterdam, the Netherlands (2019-2025)
- Coordinator research internship Master Faculty of Medicine, Vrije Universiteit, Amsterdam, the Netherlands (2019-2022)
- Funding from the Norwegian Heath Association, Alzheimer Nederland, Health Holland TKI-LSH PPP, ZonMW, European Committee, participiant in the EU FP7 project PredictND (2014-2018) and IHI project PROMINENT (2023-2028)
Research Areas
- Neurodegenerative disorders, dementia
- Digital cognitive testing
- Clinical decision support systems / Artificial intelligence
- End users experience
Publications 2026
Evaluation and lessons learned regarding Public Involvement: a panel advising on an Alzheimer's disease and related dementia cohort study
Res Involv Engagem, 12 (1)
DOI 10.1186/s40900-026-00844-1, PubMed 41593813
Comparison of Brain Age With Standard MRI Assessment for Dementia Risk Stratification in Subjective and Mild Cognitive Impairment
Neurology, 107 (5), e218418
DOI 10.1212/WNL.0000000000218418, PubMed 42574695
External Validation of SCORE2-OP for Predicting Cardiovascular Mortality in Frail Geriatric Outpatients
J Am Med Dir Assoc, 27 (4), 106102
DOI 10.1016/j.jamda.2025.106102, PubMed 41628900
Publications 2025
Sex differences in life expectancy in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD)
Alzheimers Dement (Amst), 17 (3), e70177
DOI 10.1002/dad2.70177, PubMed 40959580
Towards a national registry for Alzheimer's disease and related dementias: rationale, design, and initial observations of the ABOARD cohort
Alzheimers Res Ther, 17 (1), 123
DOI 10.1186/s13195-025-01725-7, PubMed 40448198
Exploring interdisciplinary perspectives on the implementation of personalized medicine and patient-orchestrated care in Alzheimer's disease: A qualitative study within the ABOARD research project
J Alzheimers Dis, 105 (1), 120-133
DOI 10.1177/13872877251326166, PubMed 40116704
Usability and feasibility of ADappt: a digital toolkit to support communication on diagnosis and prognosis in memory clinics
Alzheimers Res Ther, 17 (1), 218
DOI 10.1186/s13195-025-01847-y, PubMed 41039627
No sex differences in the association between regional brain structure abnormalities and cognitive functioning in a geriatric memory clinic population
Aging Brain, 7, 100137
DOI 10.1016/j.nbas.2025.100137, PubMed 40421403
Automatic MRI Volumetry Assisted Visual Assessment of the Medial Temporal Lobe in Clinical Dementia Work-Up
Brain Behav, 15 (10), e70948
DOI 10.1002/brb3.70948, PubMed 41024716
Studying gender in the experiences of patients with heart failure: A scoping review of qualitative studies and methodological recommendations
Womens Health (Lond), 21, 17455057241305078
DOI 10.1177/17455057241305078, PubMed 39883432
Deciphering Perspectives: A European Survey on Clinical Decision Support Tools for Dementia and Alzheimer's Disease
Dement Geriatr Cogn Disord, 54 (5), 284-293
DOI 10.1159/000544801, PubMed 39999809
Interrelation between domains of functioning and white matter hyperintensities in geriatric memory clinic patients: a holistic approach through network analysis
Aging Ment Health, 29 (6), 1019-1027
DOI 10.1080/13607863.2025.2450282, PubMed 39831385
What do Professionals Think of Specific Care Recommendations for Vascular Cognitive Impairment? A Delphi Study With Health Care Professionals
J Am Med Dir Assoc, 26 (5), 105546
DOI 10.1016/j.jamda.2025.105546, PubMed 40088940
The relationship between cognitive domains and everyday functioning in Alzheimer's disease
Neuropsychology, 40 (2), 117-127
DOI 10.1037/neu0001038, PubMed 41100281
Focus groups on digital cognitive assessment in the context of Alzheimer's disease
Digit Health, 11, 20552076251318903
DOI 10.1177/20552076251318903, PubMed 39944114
Publications 2024
Embedding routine health care data in clinical trials: with great power comes great responsibility
Neth Heart J, 32 (3), 106-115
DOI 10.1007/s12471-023-01837-5, PubMed 38224411
The Temporal Relation of Physical Function with Cognition and the Influence of Brain Health in the Oldest-Old
Gerontology, 71 (1), 13-27
DOI 10.1159/000542395, PubMed 39504937
Is it time for Heart-Brain clinics? A clinical survey and proposition to improve current care for cognitive problems in heart failure
Clin Cardiol, 47 (1), e24200
DOI 10.1002/clc.24200, PubMed 38183320
Regional MRI volumetry using NeuroQuant versus visual rating scales in patients with cognitive impairment and dementia
Brain Behav, 14 (2), e3397
DOI 10.1002/brb3.3397, PubMed 38600026
cCOG Web-Based Cognitive Assessment Tool
Methods Mol Biol, 2785, 311-320
DOI 10.1007/978-1-0716-3774-6_19, PubMed 38427202
Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET
PLoS One, 19 (5), e0303111
DOI 10.1371/journal.pone.0303111, PubMed 38768188
Healthcare Professionals' Perspectives on Post-Diagnostic Care for People with Vascular Cognitive Impairment: When Help Is Needed in a "No-Man's Land"
J Alzheimers Dis, 101 (3), 1001-1013
DOI 10.3233/JAD-240526, PubMed 39240640
Predicting Cognitive Decline in Amyloid-Positive Patients With Mild Cognitive Impairment or Mild Dementia
Neurology, 103 (3), e209605
DOI 10.1212/WNL.0000000000209605, PubMed 38986053
Use of a digital tool to support the diagnostic process in memory clinics-a usability study
Alzheimers Res Ther, 16 (1), 75
DOI 10.1186/s13195-024-01433-8, PubMed 38589933
Computerized decision support to optimally funnel patients through the diagnostic pathway for dementia
Alzheimers Res Ther, 16 (1), 256
DOI 10.1186/s13195-024-01614-5, PubMed 39587679
Separating dementia with Lewy bodies from Alzheimer's disease dementia using a volumetric MRI classifier
Eur Radiol, 35 (7), 3753-3767
DOI 10.1007/s00330-024-11257-7, PubMed 39739040
Hypertension and orthostatic hypotension in the elderly: a challenging balance
Lancet Reg Health Eur, 48, 101154
DOI 10.1016/j.lanepe.2024.101154, PubMed 39717228
Orthostatic hypotension and cerebral small vessel disease: A systematic review
J Cereb Blood Flow Metab, 45 (1), 13-31
DOI 10.1177/0271678X241283226, PubMed 39283022
Cerebral small vessel disease and its relationship with all-cause mortality risk: Results from the Amsterdam Ageing cohort
Arch Gerontol Geriatr, 129, 105669
DOI 10.1016/j.archger.2024.105669, PubMed 39481219
Publications 2023
Rationale and design of the ABOARD project (A Personalized Medicine Approach for Alzheimer's Disease)
Alzheimers Dement (N Y), 9 (2), e12401
DOI 10.1002/trc2.12401, PubMed 37287472
Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals
Alzheimers Res Ther, 15 (1), 131
DOI 10.1186/s13195-023-01276-9, PubMed 37543608
Determinants of informal care time, distress, depression, and quality of life in care partners along the trajectory of Alzheimer's disease
Alzheimers Dement (Amst), 15 (2), e12418
DOI 10.1002/dad2.12418, PubMed 37114014
Cardiovascular Risk Management in Persons with Dementia
J Alzheimers Dis, 93 (3), 879-889
DOI 10.3233/JAD-230019, PubMed 37125555
Minding menopause in patients with cognitive impairment: a patient's perspective and reflections on clinical practice
BMC Womens Health, 23 (1), 591
DOI 10.1186/s12905-023-02770-w, PubMed 37950260
Vascular cognitive impairment: When memory loss is not the biggest challenge
Dementia (London), 23 (1), 152-171
DOI 10.1177/14713012231214299, PubMed 37997896
Young-onset dementia in memory clinics in the Netherlands: Study design and description of PRECODE-GP
Alzheimers Dement (Amst), 15 (3), e12471
DOI 10.1002/dad2.12471, PubMed 37609004
[A survey study towards the opinions of clinicians, patients and care partners regarding computer tools in the memory clinic: sense or nonsense?]
Tijdschr Gerontol Geriatr, 54 (1)
DOI 10.36613/tgg.1875-6832/2023.01.03, PubMed 37022048
Orthostatic hypotension and its association with cerebral small vessel disease in a memory clinic population
J Hypertens, 41 (11), 1738-1744
DOI 10.1097/HJH.0000000000003525, PubMed 37589676
Publications 2022
Life satisfaction across the entire trajectory of Alzheimer's disease: A mediation analysis
Alzheimers Dement (Amst), 14 (1), e12389
DOI 10.1002/dad2.12389, PubMed 36579132
Sex-Specific Associations of Diabetes With Brain Structure and Function in a Geriatric Population
Front Aging Neurosci, 14, 885787
DOI 10.3389/fnagi.2022.885787, PubMed 35837485
Optimizing cCOG, a Web-based tool, to detect dementia with Lewy Bodies
Alzheimers Dement (Amst), 14 (1), e12379
DOI 10.1002/dad2.12379, PubMed 36569383
Development and design of a diagnostic report to support communication in dementia: Co-creation with patients and care partners
Alzheimers Dement (Amst), 14 (1), e12333
DOI 10.1002/dad2.12333, PubMed 36092691
Orthostatic hypotension and mortality risk in geriatric outpatients: the impact of duration and magnitude of the blood pressure drop
J Hypertens, 40 (6), 1107-1114
DOI 10.1097/HJH.0000000000003097, PubMed 35703878
Publications 2021
Clinical Phenotypes of Behavioral Variant Frontotemporal Dementia by Age at Onset
J Alzheimers Dis, 82 (1), 381-390
DOI 10.3233/JAD-210179, PubMed 34024833
Mortality Risk and Its Association with Geriatric Domain Deficits in Older Outpatients: The Amsterdam Ageing Cohort
Gerontology, 67 (2), 194-201
DOI 10.1159/000512048, PubMed 33440389
Comparing a Single Clinician Versus a Multidisciplinary Consensus Conference Approach for Dementia Diagnostics
J Alzheimers Dis, 83 (2), 741-751
DOI 10.3233/JAD-210278, PubMed 34366342
Slowing: A Vascular Geriatric Syndrome?
J Am Med Dir Assoc, 23 (1), 47-53.e2
DOI 10.1016/j.jamda.2021.07.031, PubMed 34454919
Assessing the Views of Professionals, Patients, and Care Partners Concerning the Use of Computer Tools in Memory Clinics: International Survey Study
JMIR Form Res, 5 (12), e31053
DOI 10.2196/31053, PubMed 34870612
Biomarker testing in MCI patients-deciding who to test
Alzheimers Res Ther, 13 (1), 14
DOI 10.1186/s13195-020-00763-7, PubMed 33413634
Managing older patients with heart failure calls for a holistic approach
ESC Heart Fail, 8 (3), 2111-2119
DOI 10.1002/ehf2.13292, PubMed 33830662
Publications 2020
Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort
J Alzheimers Dis, 76 (3), 1061-1070
DOI 10.3233/JAD-200225, PubMed 32597806
cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders
Alzheimers Dement (Amst), 12 (1), e12083
DOI 10.1002/dad2.12083, PubMed 32864411
Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy
PLoS One, 15 (1), e0226784
DOI 10.1371/journal.pone.0226784, PubMed 31940390
Publications 2019
White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities
Alzheimers Dement (N Y), 5, 107-117
DOI 10.1016/j.trci.2019.02.001, PubMed 31011621
White matter hyperintensities are related to pain intensity in an outpatient memory clinic population: preliminary findings
J Pain Res, 12, 1621-1629
DOI 10.2147/JPR.S158488, PubMed 31190972
Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study
Alzheimers Res Ther, 11 (1), 25
DOI 10.1186/s13195-019-0482-3, PubMed 30894218
Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study
Curr Alzheimer Res, 16 (2), 91-101
DOI 10.2174/1567205016666190103152425, PubMed 30605060
Detecting frontotemporal dementia syndromes using MRI biomarkers
Neuroimage Clin, 22, 101711
DOI 10.1016/j.nicl.2019.101711, PubMed 30743135
Automatically computed rating scales from MRI for patients with cognitive disorders
Eur Radiol, 29 (9), 4937-4947
DOI 10.1007/s00330-019-06067-1, PubMed 30796570
Publications 2018
Evaluating combinations of diagnostic tests to discriminate different dementia types
Alzheimers Dement (Amst), 10, 509-518
DOI 10.1016/j.dadm.2018.07.003, PubMed 30320203
Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease
Alzheimers Res Ther, 10 (1), 23
DOI 10.1186/s13195-018-0348-0, PubMed 29458426
Computer-assisted prediction of clinical progression in the earliest stages of AD
Alzheimers Dement (Amst), 10, 726-736
DOI 10.1016/j.dadm.2018.09.001, PubMed 30619929
Survival in memory clinic cohort is short, even in young-onset dementia
J Neurol Neurosurg Psychiatry, 90 (6), 726-728
DOI 10.1136/jnnp-2018-318820, PubMed 30045942
Data-Driven Differential Diagnosis of Dementia Using Multiclass Disease State Index Classifier
Front Aging Neurosci, 10, 111
DOI 10.3389/fnagi.2018.00111, PubMed 29922145
Publications 2017
MRI Visual Ratings of Brain Atrophy and White Matter Hyperintensities across the Spectrum of Cognitive Decline Are Differently Affected by Age and Diagnosis
Front Aging Neurosci, 9, 117
DOI 10.3389/fnagi.2017.00117, PubMed 28536518
Publications 2016
Differential diagnosis of neurodegenerative diseases using structural MRI data
Neuroimage Clin, 11, 435-449
DOI 10.1016/j.nicl.2016.02.019, PubMed 27104138
Integrating Biomarkers for Underlying Alzheimer's Disease in Mild Cognitive Impairment in Daily Practice: Comparison of a Clinical Decision Support System with Individual Biomarkers
J Alzheimers Dis, 50 (1), 261-70
DOI 10.3233/JAD-150548, PubMed 26577521
Publications 2014
Reviews of individual patient data (IPD) are useful for geriatrics: an overview of available IPD reviews
J Am Geriatr Soc, 62 (6), 1133-8
DOI 10.1111/jgs.12830, PubMed 24802290
Publications 2013
[Development and validation of the Informant Assessment of Geriatric Delirium Scale (I-AGeD). Recognition of delirium in geriatric patients]
Tijdschr Gerontol Geriatr, 44 (5), 206-14
DOI 10.1007/s12439-013-0028-2, PubMed 23943558
Publications 2010
An unusual presentation of a varicella zoster virus encephalitis in a patient treated for metastatic prostate cancer
J Am Geriatr Soc, 58 (12), 2437-8
DOI 10.1111/j.1532-5415.2010.03178.x, PubMed 21143452