Pierre Dillard

  • Scientist; PhD, Eng, Msc, Msc
  • +47 22 78 23 16

TCR lab

 Education:

2011-2014: PhD in Biophysics & Immunology (Centre Interdisciplinaire de Nanosciences de Marseille, Aix-Marseille University, France) "Impact of ligand presentation on the biophysics of T lymphocytes adhesion"

2009-2011: Master in Drug sciences (Pharmacy university of Strasbourg, France)

2008-2011: Master in Biotechnology specialization in Synthetic Biology (Universities of Basel, Fribourg, Karlsruhe, Switzerland and Germany)

2008-2011: Engineering degree in Biotechnology (Ecole Superieure de Biotechnologie de Strasbourg, France)

 

Research interests/projects:

- Development of Therapeutic TCR for pre-clinical validation.

- Development of new analysis and methods for the Immunotoring facility.

- Implementation of microscopy based methods for the Immunotoring facility.

 

Work experience:

2017-present: Research Scientist, Dept. of Cellular Therapy, OUS-Radiumhospitalet, Oslo, Norway

2014-2016: Postdoctoral fellow, Centre Interdisciplinaire de Nanosciences de Marseille, CNRS UMR 7325, Aix-Marseille University, Marseille, France

2011-2014: PhD student, Centre Interdisciplinaire de Nanosciences de Marseille & Laboratoire adhesion et inflammation, CNRS UMR 7325 & INSERM U1067, Aix-Marseille University, Marseille, France

2010-2011: Research scholar, New England Biolabs, Boston, USA          

 

Awards:

- SBCF 2015 Travel grant (to ASCB 2016)

- Physcell 2012 Travel grant

- Bronze medal at iGEM contest in MIT 2010

 

 

 

Publications 2019

Köksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fåne A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2019)
Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
Blood Adv, 3 (8), 1230-1243
DOI 10.1182/bloodadvances.2018029678, PubMed 30979721

Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853

Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Wälchli S (2019)
Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Oncoimmunology, 8 (3), 1558663
DOI 10.1080/2162402X.2018.1558663, PubMed 30723591

Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2019)
Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Cancer Immunol Immunother, 68 (8), 1235-1243
DOI 10.1007/s00262-019-02356-2, PubMed 31214732

Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194

Wahl A, Dinet C, Dillard P, Nassereddine A, Puech PH, Limozin L, Sengupta K (2019)
Biphasic mechanosensitivity of T cell receptor-mediated spreading of lymphocytes
Proc Natl Acad Sci U S A, 116 (13), 5908-5913
DOI 10.1073/pnas.1811516116, PubMed 30850545

Publications 2018

Dillard P, Köksal H, Inderberg EM, Wälchli S (2018)
A Spheroid Killing Assay by CAR T Cells
J Vis Exp (142)
DOI 10.3791/58785, PubMed 30596389

Våtsveen TK, Myhre MR, Steen CB, Wälchli S, Lingjærde OC, Bai B, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389

Publications 2016

Dillard P, Pi F, Lellouch AC, Limozin L, Sengupta K (2016)
Nano-clustering of ligands on surrogate antigen presenting cells modulates T cell membrane adhesion and organization
Integr Biol (Camb), 8 (3), 287-301
DOI 10.1039/c5ib00293a, PubMed 26887857

Publications 2015

Pi F, Dillard P, Alameddine R, Benard E, Wahl A, Ozerov I, Charrier A, Limozin L, Sengupta K (2015)
Size-Tunable Organic Nanodot Arrays: A Versatile Platform for Manipulating and Imaging Cells
Nano Lett, 15 (8), 5178-84
DOI 10.1021/acs.nanolett.5b01400, PubMed 26161675

Publications 2014

Dillard P, Varma R, Sengupta K, Limozin L (2014)
Ligand-mediated friction determines morphodynamics of spreading T cells
Biophys J, 107 (11), 2629-38
DOI 10.1016/j.bpj.2014.10.044, PubMed 25468342

Publications 2013

Pi F, Dillard P, Limozin L, Charrier A, Sengupta K (2013)
Nanometric protein-patch arrays on glass and polydimethylsiloxane for cell adhesion studies
Nano Lett, 13 (7), 3372-8
DOI 10.1021/nl401696m, PubMed 23808889

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