Lilach Kleinberg

  • Post doc (Helse Sør-Øst)
NGS methodology on small paraffin embedded tissue samples

Original articles

McGowan M, Kleinberg L, Halvorsen AR, Helland Å, Brustugun OT (2017)
NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
Genes Cancer, 8 (3-4), 497-504
DOI 10.18632/genesandcancer.136, PubMed 28680534

Berg J, Fjellbirkeland L, Suhrke P, Jebsen P, Lund-Iversen M, Kleinberg L, Helgeland L, Brustugun OT, Helland Å (2015)
EGFR mutation testing of lung cancer patients - Experiences from Vestfold Hospital Trust
Acta Oncol, 55 (2), 149-55
DOI 10.3109/0284186X.2015.1062537, PubMed 26313507

Lund-Iversen M, Kleinberg L, Fjellbirkeland L, Helland Å, Brustugun OT (2012)
Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations
J Thorac Oncol, 7 (9), 1471-3
DOI 10.1097/JTO.0b013e3182614a9d, PubMed 22895145

Brustugun OT, Helland Å, Fjellbirkeland L, Kleinberg L, Ariansen S, Jebsen P, Scott H, Dønnem T, Bremnes R, Berg T, Grønberg BH, Dai HY, Wahl SG, Mangseth K, Helgeland L (2012)
[Mutation testing for non-small-cell lung cancer]
Tidsskr Nor Laegeforen, 132 (8), 952-5
DOI 10.4045/tidsskr.11.1017, PubMed 22562326

Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
J Thorac Oncol, 6 (5), 947-50
DOI 10.1097/JTO.0b013e31820db209, PubMed 21623266

Annunziata CM, Stavnes HT, Kleinberg L, Berner A, Hernandez LF, Birrer MJ, Steinberg SM, Davidson B, Kohn EC (2010)
Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer
Cancer, 116 (13), 3276-84
DOI 10.1002/cncr.25190, PubMed 20564628

Dong HP, Holth A, Kleinberg L, Ruud MG, Elstrand MB, Tropé CG, Davidson B, Risberg B (2009)
Evaluation of cell surface expression of phosphatidylserine in ovarian carcinoma effusions using the annexin-V/7-AAD assay: clinical relevance and comparison with other apoptosis parameters
Am J Clin Pathol, 132 (5), 756-62
DOI 10.1309/AJCPAVFA8J3KHPRS, PubMed 19846818

Elstrand MB, Kleinberg L, Kohn EC, Tropé CG, Davidson B (2009)
Expression and clinical role of antiapoptotic proteins of the bag, heat shock, and Bcl-2 families in effusions, primary tumors, and solid metastases in ovarian carcinoma
Int J Gynecol Pathol, 28 (3), 211-21
DOI 10.1097/PGP.0b013e31818b0f5e, PubMed 19620938

Kleinberg L, Dong HP, Holth A, Risberg B, Trope' CG, Nesland JM, Flørenes VA, Davidson B (2009)
Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma
Hum Pathol, 40 (6), 795-806
DOI 10.1016/j.humpath.2008.10.019, PubMed 19157506

Kleinberg L, Pradhan M, Tropé CG, Nesland JM, Davidson B, Risberg B (2008)
Ovarian carcinoma cells in effusions show increased S-phase fraction compared to corresponding primary tumors
Diagn Cytopathol, 36 (9), 637-44
DOI 10.1002/dc.20879, PubMed 18677760

Kleinberg L, Holth A, Trope CG, Reich R, Davidson B (2008)
Claudin upregulation in ovarian carcinoma effusions is associated with poor survival
Hum Pathol, 39 (5), 747-57
DOI 10.1016/j.humpath.2007.10.002, PubMed 18439941

Dong HP, Kleinberg L, Davidson B, Risberg B (2008)
Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry
Nat Protoc, 3 (6), 955-64
DOI 10.1038/nprot.2008.77, PubMed 18546596

Dong HP, Kleinberg L, Silins I, Flørenes VA, Tropé CG, Risberg B, Nesland JM, Davidson B (2008)
Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian carcinoma
Cancer, 112 (1), 84-93
DOI 10.1002/cncr.23140, PubMed 17985388

Annunziata CM, Kleinberg L, Davidson B, Berner A, Gius D, Tchabo N, Steinberg SM, Kohn EC (2007)
BAG-4/SODD and associated antiapoptotic proteins are linked to aggressiveness of epithelial ovarian cancer
Clin Cancer Res, 13 (22 Pt 1), 6585-92
DOI 10.1158/1078-0432.CCR-07-0327, PubMed 18006758

Hoffman A, Horwitz E, Hess S, Cohen-Poradosu R, Kleinberg L, Edelberg A, Shapiro M (2007)
Implications on emergence of antimicrobial resistance as a critical aspect in the design of oral sustained release delivery systems of antimicrobials
Pharm Res, 25 (3), 667-71
DOI 10.1007/s11095-007-9373-6, PubMed 17939018

Kleinberg L, Flørenes VA, Nesland JM, Davidson B (2007)
Survivin, a member of the inhibitors of apoptosis family, is down-regulated in breast carcinoma effusions
Am J Clin Pathol, 128 (3), 389-97
DOI 10.1309/E899BG1282M5D505, PubMed 17709312

Kleinberg L, Holth A, Fridman E, Schwartz I, Shih IeM, Davidson B (2007)
The diagnostic role of claudins in serous effusions
Am J Clin Pathol, 127 (6), 928-37
DOI 10.1309/V025QRN3R9CJGNPX, PubMed 17509990

Kleinberg L, Lie AK, Flørenes VA, Nesland JM, Davidson B (2007)
Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma
Hum Pathol, 38 (7), 986-94
DOI 10.1016/j.humpath.2006.12.013, PubMed 17350081

Kleinberg L, Flørenes VA, Silins I, Haug K, Trope CG, Nesland JM, Davidson B (2007)
Nuclear expression of survivin is associated with improved survival in metastatic ovarian carcinoma
Cancer, 109 (2), 228-38
DOI 10.1002/cncr.22426, PubMed 17167759

Davidson B, Zhang Z, Kleinberg L, Li M, Flørenes VA, Wang TL, Shih IeM (2006)
Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from diffuse malignant peritoneal mesothelioma
Clin Cancer Res, 12 (20 Pt 1), 5944-50
DOI 10.1158/1078-0432.CCR-06-1059, PubMed 17062665

Kleinberg L, Flørenes VA, Skrede M, Dong HP, Nielsen S, McMaster MT, Nesland JM, Shih IeM, Davidson B (2006)
Expression of HLA-G in malignant mesothelioma and clinically aggressive breast carcinoma
Virchows Arch, 449 (1), 31-9
DOI 10.1007/s00428-005-0144-7, PubMed 16541284

Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MT, Bassarova A, Kvalheim G, Nesland JM, Reich R (2006)
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
Gynecol Oncol, 102 (3), 453-61
DOI 10.1016/j.ygyno.2006.01.034, PubMed 16494928

Bercovich D, Friedlander Y, Korem S, Houminer A, Hoffman A, Kleinberg L, Shochat C, Leitersdorf E, Meiner V (2005)
The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia
Atherosclerosis, 185 (1), 97-107
DOI 10.1016/j.atherosclerosis.2005.05.025, PubMed 16002074

Review articles

Kleinberg L, Davidson B (2009)
Cell survival and apoptosis-related molecules in cancer cells in effusions: a comprehensive review
Diagn Cytopathol, 37 (8), 613-24
DOI 10.1002/dc.21095, PubMed 19418469

Stepensky D, Kleinberg L, Hoffman A (2003)
Bone as an effect compartment : models for uptake and release of drugs
Clin Pharmacokinet, 42 (10), 863-81
DOI 10.2165/00003088-200342100-00001, PubMed 12885262

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