Our research group studies the genetics/gene expression of pancreatic, liver, and colorectal cancers with the aim of identifying biomarkers for early detection and prognosis. We utilize benign and malignant human tumor tissues and cancer cell culture models to investigate protein signaling pathways involved in cellular growth, senescence, chemotherapy response, and tumor-stroma interactions.
Long-Term Effectiveness of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality in Women and Men: A Randomized Trial
Ann Intern Med, 168 (11), 775-782
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
J Hepatol, 69 (2), 368-377
Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX
Inflamm Bowel Dis, 24 (3), 593-600