Research project groups

There are 3 project groups described as follows:

1. Neoadjuvant treatment for pancreatic cancer: towards improved patient selection and assessment of treatment effect 
Project group leader is Caroline Verbeke.  Visit her UiO home page

  • Characterization of residual, i.e., resistant tumor by broad morphological and molecular analysis of both the cancer cell population and tumor stroma
  • Analysis of novel markers predictive of distant metastasis for improved patient selection for neoadjuvant treatment

2. Molecular Mechanisms of Drug Resistance
Project group leader is Paula M De Angelis.  

  • Characterization of DNA damage response and DNA repair pathways in colorectal cancer and ulcerative colitis
  • Identification of clinically-useful biomarkers of drug response

3. Molecular and Clinical Aspects of Colorectal and Liver Tumors
Project group leader: Per Arne Andresen

  • Colorectal polyposis syndromes; APC- and MUTYH genotype-phenotype correlations in Norwegian families
  • Mechanisms involved in colorectal polyp persistence and neoplastic transition. Studies on material collected from the prospectively designed NORCCAP (Norwegian Colorectal Cancer Prevention) screening study 
  • Primary and secondary hepatic tumors and their genomic alterations in inflammatory and non-inflammatory liver diseases (coordinated by prof. em. Eide)
  • Primary sclerosing cholangitis and related liver-diseases. Pathogenesis and predisposition to malignancy (coordinated by prof. em. Eide in collaboration with the research group of Professor Tom Hemming Karlsen).
 
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