Publications Flatmark Group
Publications published since 1999 from OUS - Translational Cancer Therapy
162 publications found
Publications 2020
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Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
Ann Intern Med (in press)
DOI 10.7326/M20-4011, PubMed 33197213 -
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
Gastroenterology, 159 (6), 2146-2162.e33
DOI 10.1053/j.gastro.2020.08.018, PubMed 32805281 -
Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
Cancer Biol Ther, 21 (5), 432-440
DOI 10.1080/15384047.2020.1721252, PubMed 32098573 -
Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder
J Clin Med, 9 (4)
DOI 10.3390/jcm9040990, PubMed 32252256 -
ASO Author Reflections: Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
Ann Surg Oncol, 27 (Suppl 3), 771-772
DOI 10.1245/s10434-020-08691-4, PubMed 32495284 -
B7-H3 Immune Checkpoint Protein in Human Cancer
Curr Med Chem, 27 (24), 4062-4086
DOI 10.2174/0929867326666190517115515, PubMed 31099317 -
Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models
Transl Oncol, 13 (8), 100793
DOI 10.1016/j.tranon.2020.100793, PubMed 32447231 -
MirGeneDB 2.0: the metazoan microRNA complement
Nucleic Acids Res, 48 (D1), D1172
DOI 10.1093/nar/gkz1016, PubMed 31642479 -
MirGeneDB 2.0: the metazoan microRNA complement
Nucleic Acids Res, 48 (D1), D132-D141
DOI 10.1093/nar/gkz885, PubMed 31598695 -
Corrigendum to "Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer" [Transl Oncol 12 (8) (2019) 1038-1044]
Transl Oncol, 13 (1), 122-124
DOI 10.1016/j.tranon.2019.09.005, PubMed 31843135 -
Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
Ann Surg Oncol, 28 (1), 252-257
DOI 10.1245/s10434-020-08655-8, PubMed 32488520 -
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
Acta Oncol, 59 (7), 733-740
DOI 10.1080/0284186X.2020.1742377, PubMed 32208873 -
Cytoplasmic expression of B7-H3 and membranous EpCAM expression are associated with higher grade and survival outcomes in patients with clear cell renal cell carcinoma
Ann Diagn Pathol, 46, 151483
DOI 10.1016/j.anndiagpath.2020.151483, PubMed 32143173
Publications 2019
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High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
BMC Cancer, 19 (1), 488
DOI 10.1186/s12885-019-5724-z, PubMed 31122213 -
Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
HPB (Oxford), 21 (11), 1485-1490
DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136 -
Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
Acta Oncol, 59 (4), 404-409
DOI 10.1080/0284186X.2019.1704864, PubMed 31876430 -
Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
Cancer Immunol Immunother, 69 (3), 355-364
DOI 10.1007/s00262-019-02458-x, PubMed 31893287 -
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann Surg, 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319, PubMed 28549012 -
The coexpression of fibroblast activation protein (FAP) and basal-type markers (CK 5/6 and CD44) predicts prognosis in high-grade invasive urothelial carcinoma of the bladder
Hum Pathol, 91, 61-68
DOI 10.1016/j.humpath.2019.07.002, PubMed 31279874 -
p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
Sci Rep, 9 (1), 5839
DOI 10.1038/s41598-019-42303-w, PubMed 30967582 -
A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
Transl Oncol, 12 (7), 951-958
DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111 -
Quality of life from a randomized trial of laparoscopic or open liver resection for colorectal liver metastases
Br J Surg, 106 (10), 1372-1380
DOI 10.1002/bjs.11227, PubMed 31322735 -
ImmunoPeCa trial: Long-term outcome following intraperitoneal MOC31PE immunotoxin treatment in colorectal peritoneal metastasis
Eur J Surg Oncol, 47 (1), 134-138
DOI 10.1016/j.ejso.2019.04.014, PubMed 31036394 -
Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk
J Extracell Vesicles, 8 (1), 1578116
DOI 10.1080/20013078.2019.1578116, PubMed 30815237 -
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg, 270 (2), 193-199
DOI 10.1097/SLA.0000000000003209, PubMed 30676382 -
Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
Cold Spring Harb Mol Case Stud, 5 (2)
DOI 10.1101/mcs.a003566, PubMed 30862609 -
Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
Clin Transl Radiat Oncol, 21, 5-10
DOI 10.1016/j.ctro.2019.11.006, PubMed 31872084 -
Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
Transl Oncol, 12 (8), 1038-1044
DOI 10.1016/j.tranon.2019.04.014, PubMed 31146167 -
Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology
NPJ Precis Oncol, 3, 11
DOI 10.1038/s41698-019-0083-4, PubMed 30993208 -
A Critical Insight into the Clinical Translation of PD-1/PD-L1 Blockade Therapy in Clear Cell Renal Cell Carcinoma
Curr Urol Rep, 20 (1), 1
DOI 10.1007/s11934-019-0866-8, PubMed 30645700 -
Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma
Diagn Pathol, 14 (1), 134
DOI 10.1186/s13000-019-0919-9, PubMed 31837707 -
Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
Int J Mol Sci, 20 (5)
DOI 10.3390/ijms20051170, PubMed 30866462 -
Precise Immunodetection of PTEN Protein in Human Neoplasia
Cold Spring Harb Perspect Med, 9 (12)
DOI 10.1101/cshperspect.a036293, PubMed 31501265 -
Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
Cancer Immunol Res, 7 (5), 701-706
DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006 -
Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics
Front Oncol, 9, 1302
DOI 10.3389/fonc.2019.01302, PubMed 31921617 -
Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
Clin Exp Metastasis, 36 (6), 511-518
DOI 10.1007/s10585-019-09991-0, PubMed 31541325
Publications 2018
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DUSP5 expression associates with poor prognosis in human neuroblastoma
Exp Mol Pathol, 105 (3), 272-278
DOI 10.1016/j.yexmp.2018.08.008, PubMed 30171833 -
Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
Transl Oncol, 12 (1), 76-83
DOI 10.1016/j.tranon.2018.09.010, PubMed 30273860 -
Unicellular Origin of the Animal MicroRNA Machinery
Curr Biol, 28 (20), 3288-3295.e5
DOI 10.1016/j.cub.2018.08.018, PubMed 30318349 -
B7-H3 in Cancer - Beyond Immune Regulation
Trends Cancer, 4 (6), 401-404
DOI 10.1016/j.trecan.2018.03.010, PubMed 29860983 -
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937 -
Plant microRNAs in human sera are likely contaminants
J Nutr Biochem, 65, 139-140
DOI 10.1016/j.jnutbio.2018.07.019, PubMed 30266285 -
Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk
J Nutr, 148 (9), 1506-1507
DOI 10.1093/jn/nxy144, PubMed 30184228 -
Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
J Control Release, 293, 183-192
DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259 -
Big Strides in Cellular MicroRNA Expression
Trends Genet, 34 (3), 165-167
DOI 10.1016/j.tig.2017.12.015, PubMed 29361313 -
Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
Br J Cancer, 118 (10), 1322-1328
DOI 10.1038/s41416-018-0085-y, PubMed 29695770 -
Beyond total mesorectal excision in locally advanced rectal cancer with organ or pelvic side-wall involvement
Eur J Surg Oncol, 44 (8), 1226-1232
DOI 10.1016/j.ejso.2018.03.029, PubMed 29691115 -
Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model
Acta Oncol, 57 (9), 1216-1224
DOI 10.1080/0284186X.2018.1457223, PubMed 29630428 -
The role of protein tyrosine phosphatases in prostate cancer biology
Biochim Biophys Acta Mol Cell Res, 1866 (1), 102-113
DOI 10.1016/j.bbamcr.2018.06.016, PubMed 30401533 -
Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma
Pathology, 51 (1), 21-31
DOI 10.1016/j.pathol.2018.08.019, PubMed 30466948 -
Vertical Rectus Abdominis Musculocutaneous Flap Repair Improves Perineal Wound Healing after Abdominoperineal Resection for Irradiated Locally Advanced Rectal Cancer
Ann Surg Oncol, 25 (5), 1357-1365
DOI 10.1245/s10434-018-6363-3, PubMed 29497909 -
Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss
Genome Biol Evol, 10 (6), 1457-1470
DOI 10.1093/gbe/evy096, PubMed 29788279
Publications 2017
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MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
Oncotarget, 8 (37), 61800-61809
DOI 10.18632/oncotarget.18694, PubMed 28977905 -
Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
BMC Cancer, 17 (1), 406
DOI 10.1186/s12885-017-3365-7, PubMed 28592327 -
Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival
Acta Oncol, 56 (6), 813-818
DOI 10.1080/0284186X.2017.1287951, PubMed 28464745 -
Atp8 is in the ground pattern of flatworm mitochondrial genomes
BMC Genomics, 18 (1), 414
DOI 10.1186/s12864-017-3807-2, PubMed 28549457 -
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res, 25 (1), 255-262
DOI 10.1007/s12253-017-0355-7, PubMed 29098521 -
Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
Pigment Cell Melanoma Res, 30 (5), 467-476
DOI 10.1111/pcmr.12599, PubMed 28513992 -
Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
Ann Surg Oncol, 24 (7), 1916-1922
DOI 10.1245/s10434-017-5814-6, PubMed 28224367 -
Pathway-based classification of breast cancer subtypes
Front Biosci (Landmark Ed), 22, 1697-1712
DOI 10.2741/4566, PubMed 28410140 -
Interplay between Immune Checkpoint Proteins and Cellular Metabolism
Cancer Res, 77 (6), 1245-1249
DOI 10.1158/0008-5472.CAN-16-1647, PubMed 28246276 -
Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
Oncotarget, 8 (44), 76290-76304
DOI 10.18632/oncotarget.19350, PubMed 29100312 -
Extreme conservation of miRNA complements in opisthorchiids
Parasitol Int, 66 (6), 773-776
DOI 10.1016/j.parint.2017.09.006, PubMed 28916307 -
Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
Oncotarget, 8 (44), 76921-76934
DOI 10.18632/oncotarget.20217, PubMed 29100358 -
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
ESMO Open, 2 (2), e000158
DOI 10.1136/esmoopen-2017-000158, PubMed 28761742 -
Cytoplasmic expression of CD133 stemness marker is associated with tumor aggressiveness in clear cell renal cell carcinoma
Exp Mol Pathol, 103 (2), 218-228
DOI 10.1016/j.yexmp.2017.10.001, PubMed 29050853 -
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
Gigascience, 6 (7), 1-12
DOI 10.1093/gigascience/gix032, PubMed 28459977 -
A comprehensive profile of circulating RNAs in human serum
RNA Biol, 15 (2), 242-250
DOI 10.1080/15476286.2017.1403003, PubMed 29219730 -
A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
Exp Cell Res, 352 (2), 218-224
DOI 10.1016/j.yexcr.2017.02.005, PubMed 28189639 -
Increased expression of CD44 is associated with more aggressive behavior in clear cell renal cell carcinoma
Biomark Med, 12 (1), 45-61
DOI 10.2217/bmm-2017-0142, PubMed 29243496
Publications 2016
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The Extended Family of Protein Tyrosine Phosphatases
Methods Mol Biol, 1447, 1-23
DOI 10.1007/978-1-4939-3746-2_1, PubMed 27514797 -
The mitochondrial genome of the egg-laying flatworm Aglaiogyrodactylus forficulatus (Platyhelminthes: Monogenoidea)
Parasit Vectors, 9 (1), 285
DOI 10.1186/s13071-016-1586-2, PubMed 27188228 -
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
Cancer Med, 5 (8), 1840-9
DOI 10.1002/cam4.766, PubMed 27273130 -
Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome
Clin Oncol (R Coll Radiol), 28 (8), 532-9
DOI 10.1016/j.clon.2016.01.014, PubMed 26888115 -
Expression and clinical significance of Wee1 in colorectal cancer
Tumour Biol, 37 (9), 12133-12140
DOI 10.1007/s13277-016-5081-3, PubMed 27220319 -
The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases
PLoS One, 11 (12), e0169105
DOI 10.1371/journal.pone.0169105, PubMed 28033421 -
microRNAs as cancer biomarkers
Scand J Clin Lab Invest Suppl, 245, S80-3
DOI 10.1080/00365513.2016.1210330, PubMed 27542003 -
Individual tumor volume responses to short-course oxaliplatin-containing induction chemotherapy in locally advanced rectal cancer - Targeting the tumor for radiation sensitivity?
Radiother Oncol, 119 (3), 505-11
DOI 10.1016/j.radonc.2016.02.020, PubMed 26968754 -
Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases
Clin Exp Metastasis, 34 (1), 51-62
DOI 10.1007/s10585-016-9829-3, PubMed 27812769 -
hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma
Cell Death Discov, 2, 16081
DOI 10.1038/cddiscovery.2016.81, PubMed 28028438 -
Complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis in Norway: Prognostic factors and oncologic outcome in a national patient cohort
J Surg Oncol, 114 (2), 222-7
DOI 10.1002/jso.24290, PubMed 27173150 -
Subtype-specific micro-RNA expression signatures in breast cancer progression
Int J Cancer, 139 (5), 1117-28
DOI 10.1002/ijc.30142, PubMed 27082076 -
Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour
Clin Sarcoma Res, 6, 21
DOI 10.1186/s13569-016-0062-2, PubMed 27999655 -
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
Br J Cancer, 115 (8), 929-939
DOI 10.1038/bjc.2016.278, PubMed 27599042 -
Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
BMC Cancer, 16, 536
DOI 10.1186/s12885-016-2601-x, PubMed 27461255 -
Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
Cancer Res Treat, 49 (2), 374-386
DOI 10.4143/crt.2016.080, PubMed 27488871 -
Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
Cancer Res, 76 (8), 2231-42
DOI 10.1158/0008-5472.CAN-15-1538, PubMed 27197253 -
Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
Oncotarget, 7 (23), 34907-17
DOI 10.18632/oncotarget.8995, PubMed 27145458 -
Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
Oncotarget, 7 (6), 6891-901
DOI 10.18632/oncotarget.6902, PubMed 26771843 -
Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome
Methods Mol Biol, 1447, 25-37
DOI 10.1007/978-1-4939-3746-2_2, PubMed 27514798 -
Deciphering the function of non-coding RNAs in prostate cancer
Cancer Metastasis Rev, 35 (2), 235-62
DOI 10.1007/s10555-016-9628-y, PubMed 27221068 -
Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
Diagn Pathol, 11 (1), 50
DOI 10.1186/s13000-016-0504-4, PubMed 27316334 -
Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors
Oncotarget, 7 (15), 19997-20015
DOI 10.18632/oncotarget.7671, PubMed 26918352 -
Deep Pelvic Surgical Site Infection After Radiotherapy and Surgery for Locally Advanced Rectal Cancer
Ann Surg Oncol, 24 (3), 721-728
DOI 10.1245/s10434-016-5621-5, PubMed 27766561 -
The microRNA toolkit of insects
Sci Rep, 6, 37736
DOI 10.1038/srep37736, PubMed 27883064
Publications 2015
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Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
Br J Cancer, 113 (11), 1548-55
DOI 10.1038/bjc.2015.380, PubMed 26554649 -
Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
Clin Exp Metastasis, 32 (8), 755-67
DOI 10.1007/s10585-015-9742-1, PubMed 26349943 -
Bilateral uveal melanomas with different gene expression detected with 7 years interval
Acta Ophthalmol, 94 (1), 99-102
DOI 10.1111/aos.12857, PubMed 26496992 -
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5, PubMed 25872027 -
The revised microRNA complement of Fasciola hepatica reveals a plethora of overlooked microRNAs and evidence for enrichment of immuno-regulatory microRNAs in extracellular vesicles
Int J Parasitol, 45 (11), 697-702
DOI 10.1016/j.ijpara.2015.06.002, PubMed 26183562 -
Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
BMC Cancer, 15, 543
DOI 10.1186/s12885-015-1557-6, PubMed 26205955 -
Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells
J Enzyme Inhib Med Chem, 31 (5), 779-86
DOI 10.3109/14756366.2015.1069286, PubMed 26244271 -
Tumour exosome integrins determine organotropic metastasis
Nature, 527 (7578), 329-35
DOI 10.1038/nature15756, PubMed 26524530 -
High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer
Radiother Oncol, 118 (2), 393-8
DOI 10.1016/j.radonc.2015.11.031, PubMed 26705680 -
Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: opportunities for signaling-adapted therapies
Crit Rev Oncol Hematol, 95 (1), 114-24
DOI 10.1016/j.critrevonc.2015.01.003, PubMed 25624177 -
Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma
PLoS One, 10 (6), e0128816
DOI 10.1371/journal.pone.0128816, PubMed 26066655 -
MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer
Br J Radiol, 88 (1051), 20150097
DOI 10.1259/bjr.20150097, PubMed 25899892 -
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
Br J Cancer, 112 (11), 1772-81
DOI 10.1038/bjc.2015.154, PubMed 25942396 -
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
Exp Cell Res, 340 (2), 220-6
DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
Publications 2014
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High expression of the cysteine proteinase legumain in colorectal cancer - implications for therapeutic targeting
Eur J Cancer, 51 (1), 9-17
DOI 10.1016/j.ejca.2014.10.020, PubMed 25466510 -
B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome
BMC Cancer, 14, 602
DOI 10.1186/1471-2407-14-602, PubMed 25139714 -
Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
Br J Cancer, 110 (8), 2072-80
DOI 10.1038/bjc.2014.113, PubMed 24577056 -
Biomarkers of histone deacetylase inhibitor activity in a phase 1 combined-modality study with radiotherapy
PLoS One, 9 (2), e89750
DOI 10.1371/journal.pone.0089750, PubMed 24587009 -
The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells
J Ovarian Res, 7, 23
DOI 10.1186/1757-2215-7-23, PubMed 24528603
Publications 2013
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Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts
Anticancer Res, 33 (9), 3615-21
PubMed 24023287 -
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies
Int J Cancer, 133 (6), 1497-506
DOI 10.1002/ijc.28158, PubMed 23494569 -
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067 -
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
PLoS One, 8 (6), e66165
DOI 10.1371/journal.pone.0066165, PubMed 23824282
Publications 2012
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EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer
Br J Cancer, 107 (4), 667-74
DOI 10.1038/bjc.2012.293, PubMed 22782346 -
B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer
Int J Cancer, 131 (11), 2528-36
DOI 10.1002/ijc.27566, PubMed 22473715 -
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
BMC Cancer, 12, 505
DOI 10.1186/1471-2407-12-505, PubMed 23121918 -
Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients (vol 33, pg 73, 2012)
Tumor Biol., 33 (4), 1263-1264
Publications 2011
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Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts
Int J Cancer, 129 (3), 742-50
DOI 10.1002/ijc.25922, PubMed 21225632 -
Disseminated tumour cells as a prognostic biomarker in colorectal cancer
Br J Cancer, 104 (9), 1434-9
DOI 10.1038/bjc.2011.97, PubMed 21448171 -
Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma
PLoS One, 6 (9), e24012
DOI 10.1371/journal.pone.0024012, PubMed 21915275 -
Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins
J Immunother, 34 (5), 438-47
DOI 10.1097/CJI.0b013e31821e00ae, PubMed 21577141 -
Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients
Tumour Biol, 33 (1), 73-83
DOI 10.1007/s13277-011-0247-5, PubMed 22006279 -
B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
Int J Cancer, 130 (10), 2282-90
DOI 10.1002/ijc.26238, PubMed 21671471 -
Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles
Breast Cancer Res, 13 (4), R75
DOI 10.1186/bcr2922, PubMed 21816090
Publications 2010
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Nuclear S100A4 is a novel prognostic marker in colorectal cancer
Eur J Cancer, 46 (16), 2919-25
DOI 10.1016/j.ejca.2010.07.013, PubMed 20719498 -
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models
Hum Pathol, 41 (8), 1109-19
DOI 10.1016/j.humpath.2009.12.013, PubMed 20338618 -
Radiosensitizing drugs: lessons to be learned from the oxaliplatin story
J Clin Oncol, 28 (29), e577-8; author reply e581-3
DOI 10.1200/JCO.2010.30.0921, PubMed 20733124 -
TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins
Tumour Biol, 32 (1), 1-12
DOI 10.1007/s13277-010-0073-1, PubMed 20652782 -
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Pigment Cell Melanoma Res, 23 (3), 449-51
DOI 10.1111/j.1755-148X.2010.00690.x, PubMed 20236249 -
Immunotoxins: a promising treatment modality for metastatic melanoma?
Ochsner J, 10 (3), 193-9
PubMed 21603377 -
Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells
J Immunother, 33 (3), 272-8
DOI 10.1097/CJI.0b013e3181c54991, PubMed 20445347 -
MicroRNAs as biomarkers in colorectal cancer
Am J Pathol, 177 (4), 1592-9
DOI 10.2353/ajpath.2010.100024, PubMed 20829435 -
Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study
BMC Cancer, 10, 469
DOI 10.1186/1471-2407-10-469, PubMed 20809961 -
A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth
Cancer Immunol Immunother, 59 (11), 1665-74
DOI 10.1007/s00262-010-0892-3, PubMed 20635083
Publications 2009
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Gene expression profiles classify human osteosarcoma xenografts according to sensitivity to doxorubicin, cisplatin, and ifosfamide
Clin Cancer Res, 15 (23), 7161-9
DOI 10.1158/1078-0432.CCR-08-2816, PubMed 19920113 -
Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats (vol 44, pg 3874, 2009)
Eur. J. Med. Chem., 44 (11), 4786 -
The melanoma specific 9.2.27PE immunotoxin efficiently kills melanoma cells in vitro
Int J Cancer, 125 (1), 23-33
DOI 10.1002/ijc.24317, PubMed 19350633
Publications 2008
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S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
Melanoma Res, 18 (2), 134-40
DOI 10.1097/CMR.0b013e3282f623d9, PubMed 18337650 -
Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer?
BMC Cancer, 8, 213
DOI 10.1186/1471-2407-8-213, PubMed 18655729 -
HDAC2 deficiency and histone acetylation
Nat Genet, 40 (7), 812-3; author reply 813
DOI 10.1038/ng0708-812, PubMed 18583969
Publications 2007
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Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype
BMC Cancer, 7, 116
DOI 10.1186/1471-2407-7-116, PubMed 17603904 -
[The 75th anniversary of the Radium Hospital]
Tidsskr Nor Laegeforen, 127 (13), 1800-1
PubMed 17599133 -
Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value
Clin Exp Metastasis, 24 (5), 317-27
DOI 10.1007/s10585-006-9052-8, PubMed 17530423
Publications 2006
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AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death
Mol Cancer Ther, 5 (4), 1050-9
DOI 10.1158/1535-7163.MCT-05-0318, PubMed 16648577 -
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
Radiat Oncol, 1, 25
DOI 10.1186/1748-717X-1-25, PubMed 16887021
Publications 2005
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Lack of proinflammatory effects of free fatty acids on human umbilical cord vein endothelial cells and leukocytes
Acta Obstet Gynecol Scand, 84 (7), 672-8
DOI 10.1111/j.0001-6349.2005.00799.x, PubMed 15954878
Publications 2004
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Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin
Int J Cancer, 112 (3), 475-83
DOI 10.1002/ijc.20371, PubMed 15382075 -
Human osteosarcoma xenografts and their sensitivity to chemotherapy
Pathol Oncol Res, 10 (3), 133-41
DOI 10.1007/BF03033741, PubMed 15448748 -
Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
Eur J Cancer, 40 (10), 1593-8
DOI 10.1016/j.ejca.2004.02.023, PubMed 15196545 -
Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum
Tumour Biol, 25 (1-2), 31-40
DOI 10.1159/000077721, PubMed 15192310
Publications 2003
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Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
Br J Cancer, 88 (12), 1995-2001
DOI 10.1038/sj.bjc.6600998, PubMed 12799648 -
Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer
J Pathol, 200 (5), 589-95
DOI 10.1002/path.1381, PubMed 12898594 -
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes
J Cell Physiol, 196 (1), 113-23
DOI 10.1002/jcp.10282, PubMed 12767047 -
DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study
Int J Colorectal Dis, 19 (1), 49-54
DOI 10.1007/s00384-003-0519-7, PubMed 12827413
Publications 2002
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Immunomagnetic detection of micrometastatic cells in bone marrow of colorectal cancer patients
Clin Cancer Res, 8 (2), 444-9
PubMed 11839662 -
Expression of S100A4, E-cadherin, alpha- and beta-catenin in breast cancer biopsies
Br J Cancer, 87 (11), 1281-6
DOI 10.1038/sj.bjc.6600624, PubMed 12439718
Publications 2001
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Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
Recent Results Cancer Res, 158, 40-50
DOI 10.1007/978-3-642-59537-0_5, PubMed 11092032