Kristian Tonby

  • Consultant; MD, PhD
 

Publications 2021

Aamodt AH, Høgestøl EA, Popperud TH, Holter JC, Dyrhol-Riise AM, Tonby K, Stiksrud B, Quist-Paulsen E, Berge T, Barratt-Due A, Aukrust P, Heggelund L, Blennow K, Zetterberg H, Harbo HF (2021)
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol
DOI 10.1007/s00415-021-10517-6, PubMed 33743046

Chendi BH, Snyders CI, Tonby K, Jenum S, Kidd M, Walzl G, Chegou NN, Dyrhol-Riise AM, ScreenTB Consortium (2021)
A Plasma 5-Marker Host Biosignature Identifies Tuberculosis in High and Low Endemic Countries
Front. Immunol., 12, 608846

Christensen EE, Jørgensen MJ, Nore KG, Dahl TB, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter JC, Holten AR, Halvorsen B, Dyrhol-Riise AM (2021)
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med
DOI 10.1111/joim.13310, PubMed 34080738

Kolberg ES, Wickstrøm K, Tonby K, Dyrhol-Riise AM, Holten AR, Amundsen EK (2021)
Serum ACE as a prognostic biomarker in COVID-19: a case series
APMIS, 129 (4), 237-238
DOI 10.1111/apm.13108, PubMed 33368687

Lerum TV, Aaløkken TM, Brønstad E, Aarli B, Ikdahl E, Lund KMA, Durheim MT, Rodriguez JR, Meltzer C, Tonby K, Stavem K, Skjønsberg OH, Ashraf H, Einvik G (2021)
Dyspnoea, lung function and CT findings 3 months after hospital admission for COVID-19
Eur Respir J, 57 (4)
DOI 10.1183/13993003.03448-2020, PubMed 33303540

Watne LO, Tonby K, Holten AR, Olasveengen TM, Romundstad LG, Neerland BE (2021)
Delirium is common in patients hospitalized with COVID-19
Intern Emerg Med
DOI 10.1007/s11739-021-02715-x, PubMed 33830418

Publications 2020

Borén HK, Thaulow CM, Quist-Paulsen E, Wæhre T, Akselsen PE, Tonby K (2020)
Antibiotic use in hospitals in cases of COVID-19
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0443, PubMed 32815355

Gundem T, Olasveengen TM, Hovda KE, Gaustad K, Schøndorf C, Rostrup M, Frøyshov S, Undseth Ø, Tonby K, Holten AR, Sunde K (2020)
Ventilatory support for hypoxaemic intensive care patients with COVID-19
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0445, PubMed 32815344

Gundem T, Olasveengen TM, Hovda KE, Gaustad K, Schøndorf C, Rostrup M, Frøyshov S, Undseth Ø, Tonby K, Holten AR, Sunde K (2020)
T.M. Gundem and colleagues respond
Tidsskr Nor Laegeforen, 140 (12)
DOI 10.4045/tidsskr.20.0650, PubMed 32900164

Holten AR, Nore KG, Tveiten CEVWK, Olasveengen TM, Tonby K (2020)
Predicting severe COVID-19 in the Emergency Department
Resusc Plus, 4, 100042
DOI 10.1016/j.resplu.2020.100042, PubMed 33403367

Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538

Jøntvedt Jørgensen M, Holter JC, Christensen EE, Schjalm C, Tonby K, Pischke SE, Jenum S, Skeie LG, Nur S, Lind A, Opsand H, Enersen TB, Grøndahl R, Hermann A, Dudman S, Muller F, Ueland T, Mollnes TE, Aukrust P, Heggelund L, Holten AR, Dyrhol-Riise AM (2020)
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843

Jøntvedt Jørgensen M, Jenum S, Tonby K, Mortensen R, Walzl G, Du Plessis N, Dyrhol-Riise AM (2020)
Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors
J Leukoc Biol
DOI 10.1002/JLB.4A0720-409RR, PubMed 33155730

Nore KG, Jørgensen MJ, Dyrhol-Riise AM, Jenum S, Tonby K (2020)
Elevated Levels of Anti-Inflammatory Eicosanoids and Monocyte Heterogeneity in Mycobacterium tuberculosis Infection and Disease
Front Immunol, 11, 579849
DOI 10.3389/fimmu.2020.579849, PubMed 33304347

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Publications 2019

Mortensen R, Clemmensen HS, Woodworth JS, Therkelsen ML, Mustafa T, Tonby K, Jenum S, Agger EM, Dyrhol-Riise AM, Andersen P (2019)
Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice
Commun Biol, 2, 288
DOI 10.1038/s42003-019-0530-3, PubMed 31396568

Tonby K, Mortensen R, Ruhwald M, Dyrhol-Riise AM, Jenum S (2019)
KLRG1-Expressing CD4 T Cells Are Reduced in Tuberculosis Patients Compared to Healthy Mycobacterium tuberculosis-Infected Subjects, but Increase With Treatment
J Infect Dis, 220 (1), 174-176
DOI 10.1093/infdis/jiz056, PubMed 30888024

Publications 2016

Tonby K, Wergeland I, Lieske NV, Kvale D, Tasken K, Dyrhol-Riise AM (2016)
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
BMC Infect Dis, 16 (1), 599
DOI 10.1186/s12879-016-1938-8, PubMed 27776487

Publications 2015

Feruglio SL, Tonby K, Kvale D, Dyrhol-Riise AM (2015)
Early dynamics of T helper cell cytokines and T regulatory cells in response to treatment of active Mycobacterium tuberculosis infection
Clin Exp Immunol, 179 (3), 454-65
DOI 10.1111/cei.12468, PubMed 25313008

Lieske NV, Tonby K, Kvale D, Dyrhol-Riise AM, Tasken K (2015)
Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors
PLoS One, 10 (11), e0141903
DOI 10.1371/journal.pone.0141903, PubMed 26544592

Tonby K, Ruhwald M, Kvale D, Dyrhol-Riise AM (2015)
IP-10 measured by Dry Plasma Spots as biomarker for therapy responses in Mycobacterium Tuberculosis infection
Sci Rep, 5, 9223
DOI 10.1038/srep09223, PubMed 25783975

Wergeland I, Pullar N, Assmus J, Ueland T, Tonby K, Feruglio S, Kvale D, Damås JK, Aukrust P, Mollnes TE, Dyrhol-Riise AM (2015)
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
J Infect, 70 (4), 381-91
DOI 10.1016/j.jinf.2014.12.019, PubMed 25597826

Publications 2014

Pullar ND, Steinum H, Tonby K, Heggelund L, Leiva RA, Ofstad R, Bruun JN, Dyrhol-Riise AM (2014)
Low prevalence of positive interferon-gamma tests in HIV-positive long-term immigrants in Norway
Int J Tuberc Lung Dis, 18 (2), 180-7
DOI 10.5588/ijtld.13.0276, PubMed 24429310

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