Welcome to Per Medbøe Thorsby's research group:

Biochemical endocrinology and metabolism research group

 
Group leader<br>Per M. Thorsby
Group leader
Per M. Thorsby

Challenges
Endocrine and metabolic diseases such as diabetes, thyroid diseased and osteoporosis are major causes of morbidity in the common population. The challenges are to identify persons at risk, implement therapeutic and preventive measures and monitor effects of these actions. Adequate diagnostics and follow-up of treatment depend heavily on biomarkers in blood, urine, tears and saliva. The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers by the use of transcriptomic, proteomic and metabolomic approaches in close collaboration with the Dept of Endocrinology, OUS.

Projects

  • Metabolomic profiling of prediabetes diabetes
  • Metabolomic profiling of early stage type 1 diabetes
  • Effects of vitamin D in diabetes
  • Posttranslational modification of proteins and late complications of diabetes
  • Effects of posttranslational modifications on immunoassays
  • Gene expression in bone biopsies in osteoporosis
  • Metabolomic and proteomic profiling of tear fluid in Graves ophtalmopathy
  • Effects of alternative mRNA splicing on cholesterol metabolism

Contact information
MD, PhD, Medical head of Department: Per M Thorsby, Hormon Laboratory, Department of Medical Biochemistry, Institute of Clinical Medicine, Oslo University Hospital,  PO Box 4950 Nydalen NO-0424 Oslo, Norway Tel: +47 23033043 E-mail: p.m.thorsby@medisin.uio.no