Genome Biology Group

Rolf I. Skotheim
Group leader

We investigate cancer genomes by integrated computational and laboratory based approaches. Our aim is to identify and characterise critical genes involved in the cancer development. Such genes may serve as diagnostic or prognostic biomarkers and also as targets for future molecularly tailored therapy. Our studies are mainly focused on testicular, prostate and colorectal cancers.

RESEARCH THEMES

Transcript variants in cancer from exon microarrays and deep sequencing

Testicular germ cell tumour: Malignancy specific expression in a stem cells context (Skotheim is Principal Investigator in the Centre for Research-based Innovation in Cancer Stem Cells) and genetic studies of bilateral disease

Fusion genes: a universal detection tool and novel fusion transcripts

Group contact information

Department of Cancer Prevention, Institute for Cancer Research
Oslo University Hospital HE - Norwegian Radium Hospital
Mail address: P. O. Box 4953 Nydalen, NO-0424 Oslo, Norway
Street address: Norwegian Radium Hospital, Montebello
Phone: +47 2278 1727 / +47 2293 4000
E mail: rolf.i.skotheim(a)rr-research.no

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News & events

Publication in Nature Genetics on testicular cancer susceptibility
May 13, 2013

PhD student Deeqa Ahmed profiled in Uniforum
Apr 28, 2013

Awards from Oslo University Hospital to outstanding researchers
Apr 27, 2013

Research based innovation
Apr 23, 2013

Comprehensive review on molecular biology of germ cell tumors of the ovary
Apr 19, 2013

More news

Latest publications

Genome Biology Group

Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA, Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Jacobs KB, Korde LA, Kraggerud SM, Lothe RA, Loud JT, Rahman N, Skinner EC, Thomas DC, Wu X, Yeager M, Schumacher FR et al.
Meta-analysis identifies four new loci associated with testicular germ cell tumor
Nat Genet (in press)
PubMed 23666239

Kraggerud SM, Hoei-Hansen CE, Alagaratnam S, Skotheim RI, Abeler VM, Rajpert-De Meyts E, Lothe RA
Molecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis
Endocr Rev (in press)
PubMed 23575763

Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Timothy Bishop D, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Pablo Lewinger J, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM et al.
Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
Hum Mol Genet (in press)
PubMed 23462292

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