Genome Biology Group

 
Rolf I. Skotheim
Group leader

We investigate cancer genomes by integrated computational and laboratory based approaches. Our aim is to identify and characterise critical genes involved in the cancer development. Such genes may serve as diagnostic or prognostic biomarkers and also as targets for future molecularly tailored therapy. Our studies are mainly focused on testicular, prostate and colorectal cancers.


  


RESEARCH THEMES



Qualitative transcript variation in cancer

Testicular germ cell tumour: Malignancy specific expression in a stem cells context (Skotheim is Principal Investigator in the Centre for Research-based Innovation in Cancer Stem Cells) and genetic studies of bilateral disease

Fusion genes: a universal detection tool and novel fusion transcripts

Prostate cancer: inter focal heterogeneity of DNA base-level mutations and gene fusions

 
 

Group contact information

 
Department of Cancer Prevention, Institute for Cancer Research
Oslo University Hospital, Norwegian Radium Hospital
P.O.Box 4953 Nydalen, NO-0424 Oslo, Norway
Phone: +47 2278 1727 / +47 2293 4000
E mail: rolf.i.skotheim(a)rr-research.no