PubMed registered articles

Mouldy Sioud's group

Publications published since 1971 or in press from Molecular Medicine

180 publications found

Publications 2010

  1. Abraham D, Zins K, Sioud M, Lucas T, Schäfer R, Stanley ER, Aharinejad S (2010)
    Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
    Int J Cancer, 126 (6), 1339-52
    PubMed 19711348
  2. Cekaite L, Clancy T, Sioud M (2010)
    Increased miR-21 expression during human monocyte differentiation into DCs
    Front Biosci (Elite Ed), 2, 818-28
    PubMed 20515755
  3. Fløisand Y, Sioud M (2010)
    Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications
    Methods Mol Biol, 629, 507-23
    PubMed 20387168
  4. Iversen PO, Sørensen DR, Sioud M (2010)
    A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia
    Thromb Haemost, 104 (2), 350-4
    PubMed 20539915
  5. Mobergslien A, Sioud M (2010)
    Optimized protocols for siRNA delivery into monocytes and dendritic cells
    Methods Mol Biol, 629, 71-85
    PubMed 20387143
  6. Sioud M (2010)
    Development of TLR7/8 small RNA antagonists
    Methods Mol Biol, 629, 387-94
    PubMed 20387163
  7. Sioud M (2010)
    Recent advances in small interfering RNA sensing by the immune system
    N Biotechnol, 27 (3), 236-42
    PubMed 20219711
  8. Sioud M (2010)
    RNA therapeutics: function, design, and delivery. Preface
    Methods Mol Biol, 629, v-vii
    PubMed 20394129
  9. Sioud M (2010)
    Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate
    Methods Mol Biol, 629, 395-404
    PubMed 20387164
  10. Sioud M (2010)
    What are the key targeted delivery technologies of siRNA now?
    Methods Mol Biol, 629, 93-107
    PubMed 20387145
  11. Sioud M (2010)
    Overcoming self-tolerance to tumour cells
    Methods Mol Biol, 629, 495-505
    PubMed 20387167
  12. Sioud M (2010)
    Advances in RNA sensing by the immune system: separation of siRNA unwanted effects from RNA interference
    Methods Mol Biol, 629, 33-52
    PubMed 20387141
  13. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    PubMed 20387154
  14. Sioud M, Mobergslien A, Boudabous A, Fløisand Y (2010)
    Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation
    Scand J Immunol, 71 (4), 267-74
    PubMed 20384870
  15. Sørensen DR, Sioud M (2010)
    Systemic delivery of synthetic siRNAs
    Methods Mol Biol, 629, 87-91
    PubMed 20387144
  16. Yamazaki T, Wälchli S, Fujita T, Ryser S, Hoshijima M, Schlegel W, Kuroda S, Maturana AD (2010)
    Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy
    Cardiovasc Res, 86 (3), 374-82
    PubMed 20097676

Publications 2009

  1. Aharinejad S, Sioud M, Lucas T, Abraham D (2009)
    Targeting stromal-cancer cell interactions with siRNAs
    Methods Mol Biol, 487, 243-66
    PubMed 19301651
  2. Cekaite L, Hovig E, Sioud M (2009)
    Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
    Methods Mol Biol, 524, 273-85
    PubMed 19377952
  3. Flatekval GF, Sioud M (2009)
    Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase
    Immunology, 128 (1 Suppl), e837-48
    PubMed 19740345
  4. Hauge H, Fjelland KE, Sioud M, Aasheim HC (2009)
    Evidence for the involvement of FAM110C protein in cell spreading and migration
    Cell Signal, 21 (12), 1866-73
    PubMed 19698782
  5. Iversen PO, Semaeva E, Sorensen DR, Wiig H, Sioud M (2009)
    Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells
    Transl Oncol, 2 (4), 242-6
    PubMed 19956385
  6. Nygren MK, Døsen-Dahl G, Stubberud H, Wälchli S, Munthe E, Rian E (2009)
    beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells
    Exp Hematol, 37 (2), 225-33
    PubMed 19101069
  7. Sioud M (2009)
    Deciphering the code of innate immunity recognition of siRNAs
    Methods Mol Biol, 487, 41-59
    PubMed 19301641
  8. Sioud M (2009)
    Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines?
    Scand J Immunol, 70 (6), 516-25
    PubMed 19906192
  9. Sioud M (2009)
    Targeted delivery of antisense oligonucleotides and siRNAs into mammalian cells
    Methods Mol Biol, 487, 61-82
    PubMed 19301642
  10. Sioud M, Boudabous A, Cekaite L (2009)
    Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
    Int J Mol Med, 23 (1), 33-9
    PubMed 19082504
  11. Sioud M, Fløisand Y (2009)
    NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation
    J Leukoc Biol, 85 (6), 939-46
    PubMed 19244164
  12. Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
    SNX4 in complex with clathrin and dynein: implications for endosome movement
    PLoS One, 4 (6), e5935
    PubMed 19529763
  13. Stronen E, Abrahamsen IW, Gaudernack G, Wälchli S, Munthe E, Buus S, Johansen FE, Lund-Johansen F, Olweus J (2009)
    Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells
    Scand J Immunol, 69 (4), 319-28
    PubMed 19284496
  14. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    PubMed 19289168

Publications 2008

  1. Abraham D, Zins K, Sioud M, Lucas T, Aharinejad S (2008)
    Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
    Front Biosci, 13, 5571-9
    PubMed 18508606
  2. Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB (2008)
    The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
    Oncogene, 27 (39), 5182-94
    PubMed 18469852
  3. Furset G, Fløisand Y, Sioud M (2008)
    Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
    Immunology, 123 (2), 263-71
    PubMed 17725606
  4. Maturana AD, Wälchli S, Iwata M, Ryser S, Van Lint J, Hoshijima M, Schlegel W, Ikeda Y, Tanizawa K, Kuroda S (2008)
    Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel
    Cardiovasc Res, 78 (3), 458-65
    PubMed 18296710
  5. Shadidi M, Sørensen D, Dybwad A, Furset G, Sioud M (2008)
    Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma
    Int J Oncol, 32 (1), 241-7
    PubMed 18097564
  6. Sioud M (2008)
    Does the understanding of immune activation by RNA predict the design of safe siRNAs?
    Front Biosci, 13, 4379-92
    PubMed 18508517
  7. Sioud M, Cekaite L (2008)
    Expression profiling of microRNAs in cancer cells: technical considerations
    Methods Mol Biol, 439, 179-90
    PubMed 18370103
  8. Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
    Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
    Mol Cell Biol, 28 (12), 4129-41
    PubMed 18411303
  9. Walchli S, Sioud M (2008)
    Vector-based delivery of siRNAs: in vitro and in vivo challenges
    Front Biosci, 13, 3488-93
    PubMed 18508450

Publications 2007

  1. Aharinejad S, Sioud M, Lucas T, Abraham D (2007)
    Target validation using RNA interference in solid tumors
    Methods Mol Biol, 361, 227-38
    PubMed 17172715
  2. Cekaite L, Furset G, Hovig E, Sioud M (2007)
    Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    J Mol Biol, 365 (1), 90-108
    PubMed 17054988
  3. Cekaite L, Hovig E, Sioud M (2007)
    Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
    Methods Mol Biol, 360, 335-48
    PubMed 17172738
  4. Furset G, Sioud M (2007)
    Design of bifunctional siRNAs: combining immunostimulation and gene-silencing in one single siRNA molecule
    Biochem Biophys Res Commun, 352 (3), 642-9
    PubMed 17150189
  5. Røsok Ø, Sioud M (2007)
    Discovery of differentially expressed genes: technical considerations
    Methods Mol Biol, 360, 115-29
    PubMed 17172727
  6. Sioud M (2007)
    An overview of the immune system and technical advances in tumor antigen discovery and validation
    Methods Mol Biol, 360, 277-318
    PubMed 17172735
  7. Sioud M (2007)
    RNA interference and innate immunity
    Adv Drug Deliv Rev, 59 (2-3), 153-63
    PubMed 17459518
  8. Sioud M (2007)
    Main approaches to target discovery and validation
    Methods Mol Biol, 360, 1-12
    PubMed 17172722
  9. Sioud M, Fløisand Y (2007)
    TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response
    Eur J Immunol, 37 (10), 2834-46
    PubMed 17853407
  10. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    PubMed 17658482
  11. Sioud M, Leirdal M (2007)
    Druggable signaling proteins
    Methods Mol Biol, 361, 1-24
    PubMed 17172705
  12. Sioud M, Melien O (2007)
    Treatment options and individualized medicine
    Methods Mol Biol, 361, 327-40
    PubMed 17172721
  13. Zins K, Abraham D, Sioud M, Aharinejad S (2007)
    Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
    Cancer Res, 67 (3), 1038-45
    PubMed 17283136

Publications 2006

  1. Angell-Petersen E, Spetalen S, Madsen SJ, Sun CH, Peng Q, Carper SW, Sioud M, Hirschberg H (2006)
    Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
    J Neurosurg, 104 (1), 109-17
    PubMed 16509154
  2. Borowiec A, Lechward K, Tkacz-Stachowska K, Sk?adanowski AC (2006)
    Adenosine as a metabolic regulator of tissue function: production of adenosine by cytoplasmic 5'-nucleotidases
    Acta Biochim Pol, 53 (2), 269-78
    PubMed 16770441
  3. Huynh T, Wälchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem Biophys Res Commun, 350 (4), 854-9
    PubMed 17034763
  4. Ji Z, Yang G, Shahzidi S, Tkacz-Stachowska K, Suo Z, Nesland JM, Peng Q (2006)
    Induction of hypoxia-inducible factor-1alpha overexpression by cobalt chloride enhances cellular resistance to photodynamic therapy
    Cancer Lett, 244 (2), 182-9
    PubMed 16427735
  5. Sioud M (2006)
    Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses
    Eur J Immunol, 36 (5), 1222-30
    PubMed 16609928
  6. Sioud M (2006)
    RNA interference below the immune radar
    Nat Biotechnol, 24 (5), 521-2
    PubMed 16680132
  7. Sioud M (2006)
    Innate sensing of self and non-self RNAs by Toll-like receptors
    Trends Mol Med, 12 (4), 167-76
    PubMed 16530484
  8. Sioud M (2006)
    Ribozymes and siRnas: from structure to preclinical applications
    Handb Exp Pharmacol (173), 223-42
    PubMed 16594618
  9. Sioud M (2006)
    RNAi therapy: antibodies guide the way
    Gene Ther, 13 (3), 194-5
    PubMed 17243203
  10. Sioud M, Fløisand Y, Forfang L, Lund-Johansen F (2006)
    Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
    J Mol Biol, 364 (5), 945-54
    PubMed 17049554
  11. Sioud M, Furset G (2006)
    Molecular basis for the immunostimulatory potency of small interfering RNAs
    J Biomed Biotechnol, 2006 (4), 23429
    PubMed 17057361
  12. Sioud M, Haoudi A (2006)
    RNA interference
    J Biomed Biotechnol, 2006 (4), 89018
    PubMed 17057373
  13. Thomassen GO, Røsok O, Rognes T (2006)
    Computational prediction of microRNAs encoded in viral and other genomes
    J Biomed Biotechnol, 2006 (4), 95270
    PubMed 17057374

Publications 2005

  1. Furre IE, Shahzidi S, Luksiene Z, Møller MT, Borgen E, Morgan J, Tkacz-Stachowska K, Nesland JM, Peng Q (2005)
    Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells
    Cancer Res, 65 (23), 11051-60
    PubMed 16322255
  2. Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Aasheim HC (2005)
    Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
    Oncogene, 24 (7), 1159-73
    PubMed 15580290
  3. Røsok O, Sioud M (2005)
    Systematic search for natural antisense transcripts in eukaryotes (review)
    Int J Mol Med, 15 (2), 197-203
    PubMed 15647831
  4. Sioud M (2005)
    On the delivery of small interfering RNAs into mammalian cells
    Expert Opin Drug Deliv, 2 (4), 639-51
    PubMed 16296791
  5. Sioud M (2005)
    siRNA delivery in vivo
    Methods Mol Biol, 309, 237-49
    PubMed 15990404
  6. Sioud M (2005)
    Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    J Mol Biol, 348 (5), 1079-90
    PubMed 15854645
  7. Sioud M, Iversen PO (2005)
    Ribozymes, DNAzymes and small interfering RNAs as therapeutics
    Curr Drug Targets, 6 (6), 647-53
    PubMed 16178798
  8. Sioud M, Røsok Ø (2005)
    High-throughput analysis of microRNA gene expression using sensitive probes
    Methods Mol Biol, 309, 311-20
    PubMed 15990410
  9. Sioud M, Wälchli S (2005)
    Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
    Methods Mol Biol, 309, 83-91
    PubMed 15990399
  10. Tkacz-Stachowska K, Lechward K, Skladanowski AC (2005)
    Isolation and characterization of pigeon breast muscle cytosolic 5'-nucleotidase-I (cN-I)
    Acta Biochim Pol, 52 (4), 789-96
    PubMed 15940349

Publications 2004

  1. Aharinejad S, Paulus P, Sioud M, Hofmann M, Zins K, Schäfer R, Stanley ER, Abraham D (2004)
    Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    Cancer Res, 64 (15), 5378-84
    PubMed 15289345
  2. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-82
    PubMed 15352232
  3. Hirschberg H, Madsen S, Angell-Petersen E, Peng Q, Sioud M, Sun CH, Sorensen DR (2004)
    Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma
    P SOC PHOTO-OPT INSTRUM ENG, 5312, 405-414
  4. Iversen PO, Sioud M (2004)
    Inhibition of gene expression by nucleic acid enzymes in rodent models of human disease
    Methods Mol Biol, 252, 451-6
    PubMed 15017070
  5. Leirdal M, Shadidy M, Røsok Ø, Sioud M (2004)
    Identification of genes differentially expressed in breast cancer cell line SKBR3: potential identification of new prognostic biomarkers
    Int J Mol Med, 14 (2), 217-22
    PubMed 15254768
  6. Leirdal M, Sioud M (2004)
    Gene-array analysis of glioma cells after treatment with an anti-PKCalpha siRNA: a general protocol
    Methods Mol Biol, 252, 493-500
    PubMed 15017074
  7. Røsok O, Sioud M (2004)
    An experimental approach for systematic identification of antisense transcripts
    Discov Med, 4 (20), 58-60
    PubMed 20705023
  8. Røsok Ø, Sioud M (2004)
    Systematic identification of sense-antisense transcripts in mammalian cells
    Nat Biotechnol, 22 (1), 104-8
    PubMed 14704709
  9. Shadidi M, Sioud M (2004)
    Selection of peptides for specific delivery of oligonucleotides into cancer cells
    Methods Mol Biol, 252, 569-80
    PubMed 15017081
  10. Sioud M (2004)
    Ribozyme- and siRNA-mediated mRNA degradation: a general introduction
    Methods Mol Biol, 252, 1-8
    PubMed 15017038
  11. Sioud M (2004)
    Therapeutic siRNAs
    Trends Pharmacol Sci, 25 (1), 22-8
    PubMed 14723975
  12. Sioud M (2004)
    Therapeutic potential of small interfering RNAs
    Drug Future, 29 (7), 741-750
  13. Sioud M, Leirdal M (2004)
    Potential design rules and enzymatic synthesis of siRNAs
    Methods Mol Biol, 252, 457-69
    PubMed 15017071
  14. Sioud M, Røsok O (2004)
    Profiling microRNA expression using sensitive cDNA probes and filter arrays
    Biotechniques, 37 (4), 574-6, 578-80
    PubMed 15517969
  15. Sioud M, Sørensen DR (2004)
    Systemic delivery of synthetic siRNAs
    Methods Mol Biol, 252, 515-22
    PubMed 15017077

Publications 2003

  1. Dybwad A, Lambin P, Sioud M, Zouali M (2003)
    Probing the specificity of human myeloma proteins with a random peptide phage library
    Scand J Immunol, 57 (6), 583-90
    PubMed 12791097
  2. Shadidi M, Sioud M (2003)
    Selective targeting of cancer cells using synthetic peptides
    Drug Resist Updat, 6 (6), 363-71
    PubMed 14744500
  3. Shadidi M, Sioud M (2003)
    Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
    FASEB J, 17 (2), 256-8
    PubMed 12490548
  4. Sioud M, Sørensen D (2003)
    Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
    Eur J Immunol, 33 (1), 38-45
    PubMed 12594830
  5. Sioud M, Sørensen DR (2003)
    Cationic liposome-mediated delivery of siRNAs in adult mice
    Biochem Biophys Res Commun, 312 (4), 1220-5
    PubMed 14652004
  6. Sørensen DR, Leirdal M, Sioud M (2003)
    Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    J Mol Biol, 327 (4), 761-6
    PubMed 12654261

Publications 2002

  1. Iversen PO, Emanuel PD, Sioud M (2002)
    Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
    Blood, 99 (11), 4147-53
    PubMed 12010819
  2. Leirdal M, Sioud M (2002)
    Gene silencing in mammalian cells by preformed small RNA duplexes
    Biochem Biophys Res Commun, 295 (3), 744-8
    PubMed 12099702
  3. Leirdal M, Sioud M (2002)
    [Tyrosine kinase receptor-ras-ERK signal transduction pathway as therapeutic tarfet in cancer]
    Tidsskr Nor Laegeforen, 122 (2), 178-82
    PubMed 11873574
  4. Machon O, van den Bout CJ, Backman M, Røsok Ø, Caubit X, Fromm SH, Geronimo B, Krauss S (2002)
    Forebrain-specific promoter/enhancer D6 derived from the mouse Dach1 gene controls expression in neural stem cells
    Neuroscience, 112 (4), 951-66
    PubMed 12088753
  5. Sioud M (2002)
    How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry
    Mol Med, 8 (3), 115-9
    PubMed 12142543
  6. Sorensen DR, Leirdal M, Iversen PO, Sioud M (2002)
    Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma
    Neoplasia, 4 (6), 474-9
    PubMed 12407440
  7. van den Bout CJ, Machon O, Røsok Ø, Backman M, Krauss S (2002)
    The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus
    Mech Dev, 110 (1-2), 179-82
    PubMed 11744379

Publications 2001

  1. Hansen MH, Ostenstad B, Sioud M (2001)
    Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour
    Int J Oncol, 19 (6), 1303-9
    PubMed 11713604
  2. Hansen MH, Ostenstad B, Sioud M (2001)
    Antigen-specific IgG antibodies in stage IV long-time survival breast cancer patients
    Mol Med, 7 (4), 230-9
    PubMed 11471567
  3. Iversen PO, Nicolaysen G, Sioud M (2001)
    DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure
    Am J Physiol Heart Circ Physiol, 281 (5), H2211-7
    PubMed 11668085
  4. Melien O, Christoffersen T, Sioud M (2001)
    Evidence for the involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytes
    BMC Cell Biol, 2, 13
    PubMed 11495629
  5. Shadidi M, Sioud M (2001)
    An anti-leukemic single chain Fv antibody selected from a synthetic human phage antibody library
    Biochem Biophys Res Commun, 280 (2), 548-52
    PubMed 11162553
  6. Sioud M (2001)
    Nucleic acid enzymes as a novel generation of anti-gene agents
    Curr Mol Med, 1 (5), 575-88
    PubMed 11899232
  7. Sioud M, Hansen MH (2001)
    Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
    Eur J Immunol, 31 (3), 716-25
    PubMed 11241275

Publications 2000

  1. Hansen MH, Dybwad A, Førre O, Sioud M (2000)
    Probing antinuclear antibody specificities by peptide phage display libraries
    Clin Exp Rheumatol, 18 (4), 465-72
    PubMed 10949721
  2. Josefsen D, Myklebust JH, Lømo J, Sioud M, Blomhoff HK, Smeland EB (2000)
    Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
    Stem Cells, 18 (4), 261-72
    PubMed 10924092
  3. Leirdal M, Sioud M (2000)
    Protein kinase Calpha isoform regulates the activation of the MAP kinase ERK1/2 in human glioma cells: involvement in cell survival and gene expression
    Mol Cell Biol Res Commun, 4 (2), 106-10
    PubMed 11170840
  4. Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
    Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
    Blood, 95 (2), 510-8
    PubMed 10627456
  5. Røsok O, Pedeutour F, Odeberg J, Lundeberg J, Aasheim HC (2000)
    The C1orf9 gene encodes a putative transmembrane member of a novel protein family
    Biochem Biophys Res Commun, 267 (3), 855-62
    PubMed 10673381
  6. Sioud M, Hansen M, Dybwad A (2000)
    Profiling the immune responses in patient sera with peptide and cDNA display libraries
    Int J Mol Med, 6 (2), 123-8
    PubMed 10891554
  7. Sioud M, Leirdal M (2000)
    Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application
    J Mol Biol, 296 (3), 937-47
    PubMed 10677293
  8. Sioud M, Leirdal M (2000)
    Therapeutic RNA and DNA enzymes
    Biochem Pharmacol, 60 (8), 1023-6
    PubMed 11007937

Publications 1999

  1. Leirdal M, Sioud M (1999)
    Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells
    Br J Cancer, 80 (10), 1558-64
    PubMed 10408397
  2. Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
    Expression of a novel factor in human breast cancer cells with metastatic potential
    Cancer Res, 59 (18), 4675-80
    PubMed 10493524
  3. Røsok O, Pedeutour F, Ree AH, Aasheim HC (1999)
    Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis
    Genomics, 61 (1), 44-54
    PubMed 10512679
  4. Shadidy M, Caubit X, Olsen R, Seternes OM, Moens U, Krauss S (1999)
    Biochemical analysis of mouse FKBP60, a novel member of the FKPB family
    Biochim Biophys Acta, 1446 (3), 295-307
    PubMed 10524204
  5. Sioud M (1999)
    Application of preformed hammerhead ribozymes in the gene therapy of cancer (review)
    Int J Mol Med, 3 (4), 381-4
    PubMed 10085409
  6. Sioud M, Leirdal M (1999)
    Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg(2+) binding and efficient cleavage by hammerhead ribozyme
    Biochem Biophys Res Commun, 262 (2), 461-6
    PubMed 10462497
  7. Ståhl S, Odeberg J, Larsson M, Røsok O, Ree AH, Lundeberg J (1999)
    Solid-phase differential display and bacterial expression systems in selection and functional analysis of cDNAs
    Methods Enzymol, 303, 495-511
    PubMed 10349662

Publications 1998

  1. Iversen PO, Sioud M (1998)
    Modulation of granulocyte-macrophage colony-stimulating factor gene expression by a tumor necrosis factor specific ribozyme in juvenile myelomonocytic leukemic cells
    Blood, 92 (11), 4263-8
    PubMed 9834232
  2. Leirdal M, Sioud M (1998)
    High cleavage activity and stability of hammerhead ribozymes with a uniform 2'-amino pyrimidine modification
    Biochem Biophys Res Commun, 250 (1), 171-4
    PubMed 9735351
  3. Odeberg J, Røsok O, Gudmundsson GH, Ahmadian A, Roshani L, Williams C, Larsson C, Pontén F, Uhlén M, Asheim HC, Lundeberg J (1998)
    Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31
    Genomics, 50 (2), 213-21
    PubMed 9653648
  4. Sioud M, Mellbye O, Førre O (1998)
    Analysis of the NF-kappa B p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA
    Clin Exp Rheumatol, 16 (2), 125-34
    PubMed 9536387
  5. Sioud M, Sørensen DR (1998)
    A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth
    Nat Biotechnol, 16 (6), 556-61
    PubMed 9624687

Publications 1997

  1. Dybwad A, F?rre O, Sioud M (1997)
    Probing for cerebrospinal fluid antibody specificities by a panel of random peptide libraries
    Autoimmunity, 25 (2), 85-9
    PubMed 9189009
  2. Sioud M (1997)
    Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates
    Nucleic Acids Res, 25 (2), 333-8
    PubMed 9016562
  3. Sioud M, Opstad A, Hendry P, Lockett TJ, Jennings PA, McCall MJ (1997)
    A minimised hammerhead ribozyme with activity against interleukin-2 in human cells
    Biochem Biophys Res Commun, 231 (2), 397-402
    PubMed 9070287

Publications 1996

  1. Dybwad A, Førre O, Sioud M (1996)
    Increased serum and synovial fluid antibodies to immunoselected peptides in patients with rheumatoid arthritis
    Ann Rheum Dis, 55 (7), 437-41
    PubMed 8774161
  2. Fakhfakh F, Ayadi H, Bahloul Z, Jarraya A, Sioud M, Zouali M (1996)
    Antibody epitopes probed by immunoselected phage-display library peptides in members of a family with various rheumatic manifestations
    Clin Exp Rheumatol, 14 (6), 607-11
    PubMed 8978954
  3. Røsok O, Odeberg J, Rode M, Stokke T, Funderud S, Smeland E, Lundeberg J (1996)
    Solid-phase method for differential display of genes expressed in hematopoietic stem cells
    Biotechniques, 21 (1), 114-21
    PubMed 8816245
  4. Sioud M (1996)
    Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo
    Eur J Immunol, 26 (5), 1026-31
    PubMed 8647163
  5. Sioud M, Førre O, Dybwad A (1996)
    Selection of ligands for polyclonal antibodies from random peptide libraries: potential identification of (auto)antigens that may trigger B and T cell responses in autoimmune diseases
    Clin Immunol Immunopathol, 79 (2), 105-14
    PubMed 8620616
  6. Sioud M, Jespersen L (1996)
    Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase
    J Mol Biol, 257 (4), 775-89
    PubMed 8636981
  7. Tougourti MN, Sioud M, Hassen Z, Bouhali R, Hamza M (1996)
    [Psychiatric disorders and endocrine diseases. Apropos of a 8 cases]
    Tunis Med, 74 (12), 549-52
    PubMed 9506057

Publications 1995

  1. Dybwad A, Bogen B, Natvig JB, Førre O, Sioud M (1995)
    Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
    Clin Exp Immunol, 102 (2), 438-42
    PubMed 7586703
  2. Dybwad A, Førre O, Natvig JB, Sioud M (1995)
    Structural characterization of peptides that bind synovial fluid antibodies from RA patients: a novel strategy for identification of disease-related epitopes using a random peptide library
    Clin Immunol Immunopathol, 75 (1), 45-50
    PubMed 7533685
  3. Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Førre O (1995)
    Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet
    Scand J Rheumatol, 24 (2), 85-93
    PubMed 7747149
  4. Kjeldsen-Kragh J, Rashid T, Dybwad A, Sioud M, Haugen M, Førre O, Ebringer A (1995)
    Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet
    Ann Rheum Dis, 54 (3), 221-4
    PubMed 7748020
  5. Ostenstad B, Dybwad A, Lea T, Førre O, Vinje O, Sioud M (1995)
    Evidence for monoclonal expansion of synovial T cells bearing V alpha 2.1/V beta 5.5 gene segments and recognizing a synthetic peptide that shares homology with a number of putative autoantigens
    Immunology, 86 (2), 168-75
    PubMed 7490114
  6. Ostenstad B, Sioud M, Schlichting E, Lea T, Harboe M (1995)
    Freshly isolated tumour-infiltrating T-lymphocytes have a high cytotoxic potential, as measured by their ability to induce apoptosis in the target cell
    Scand J Immunol, 41 (1), 42-8
    PubMed 7824887
  7. Tougourti MN, Sioud M, Hamza M (1995)
    [Cerebrovascular accidents in Horton's disease. Apropos of a case]
    Tunis Med, 73 (5), 195-9
    PubMed 9507283
  8. Tougourti MN, Sioud M, Kheder L, Hamza M, Miled M (1995)
    [Antiphospholipid syndrome]
    Tunis Med, 73 (2), 95-103
    PubMed 9506150

Publications 1994

  1. NATVIG JB, WILSON KB, QUAYLE A, SULEYMAN S, KJELDSENKRAGH J, FORRE O, SIOUD M, CAPRA JD (1994)
    T-CELL RECEPTOR VARIABLE GENE REPERTOIRE IN RHEUMATOID SYNOVIAL T-CELLS RESPONDING TO BCG
    NATO ADV SCI INST SERIES H CE, 80, 191-196
  2. Ostenstad B, Sioud M, Lea T, Schlichting E, Harboe M (1994)
    Limited heterogeneity in the T-cell receptor V-gene usage in lymphocytes infiltrating human colorectal tumours
    Br J Cancer, 69 (6), 1078-82
    PubMed 8198973
  3. Sioud M (1994)
    Interaction between tumour necrosis factor alpha ribozyme and cellular proteins. Involvement in ribozyme stability and activity
    J Mol Biol, 242 (5), 619-29
    PubMed 7932719
  4. Sioud M, Dybwad A, Jespersen L, Suleyman S, Natvig JB, Førre O (1994)
    Characterization of naturally occurring autoantibodies against tumour necrosis factor-alpha (TNF-alpha): in vitro function and precise epitope mapping by phage epitope library
    Clin Exp Immunol, 98 (3), 520-5
    PubMed 7994916
  5. Sioud M, Opstad A, Zhao JQ, Levitz R, Benham C, Drlica K (1994)
    In vivo decay kinetic parameters of hammerhead ribozymes
    Nucleic Acids Res, 22 (25), 5571-5
    PubMed 7838709
  6. SULEYMAN S, THOMPSON KM, FORRE O, SIOUD M, RANDEN I, MAGEED RA, NATVIG JB (1994)
    3 NEW CROSS-REACTING IDIOTOPES AS MARKERS FOR THE PRODUCTS OF 2 DISTINCT HUMAN V(H)3 GENES EXPRESSED IN THE EARLY REPERTOIRE
    Scand. J. Immunol., 40 (6), 681-690
  7. Suleyman S, Thompson KM, Førre O, Sioud M, Randen I, Mageed RA, Natvig JB (1994)
    Three new cross-reacting idiotopes as markers for the products of two distinct human VH3 genes expressed in the early repertoire
    Scand J Immunol, 40 (6), 681-90
    PubMed 7527936
  8. Tougourti MN, Sioud M, Khedher I, Houman H, Hamza M, Miled M (1994)
    [Iatrogenic accidents in the hospital environment]
    Tunis Med, 72 (11), 625-30
    PubMed 7762090

Publications 1993

  1. Dybwad A, Førre O, Kjeldsen-Kragh J, Natvig JB, Sioud M (1993)
    Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
    Eur J Immunol, 23 (12), 3189-93
    PubMed 7504991
  2. Førre O, Sioud M (1993)
    T cell receptor variable region gene usage in juvenile chronic arthritis
    Clin Exp Rheumatol, 11 Suppl 9, S43-6
    PubMed 8354007
  3. Kjeldsen-Kragh J, Quayle AJ, Skålhegg BS, Sioud M, Førre O (1993)
    Selective activation of resting human gamma delta T lymphocytes by interleukin-2
    Eur J Immunol, 23 (9), 2092-9
    PubMed 8370391
  4. Suleyman S, Hosono O, Sioud M, Randen I, Thompson KM, Førre O, Natvig JB (1993)
    Differentiation of human lambda I variable regions with a monoclonal antibody to a defined, germ-line-encoded idiotope correlates with V lambda Ia chemical structure
    J Immunol, 150 (12), 5466-75
    PubMed 8515071

Publications 1992

  1. Quayle AJ, Wilson KB, Li SG, Kjeldsen-Kragh J, Oftung F, Shinnick T, Sioud M, Førre O, Capra JD, Natvig JB (1992)
    Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid
    Eur J Immunol, 22 (5), 1315-22
    PubMed 1577070
  2. Sioud M, Kjeldsen-Kragh J, Suleyman S, Vinje O, Natvig JB, Førre O (1992)
    Limited heterogeneity of T cell receptor variable region gene usage in juvenile rheumatoid arthritis synovial T cells
    Eur J Immunol, 22 (9), 2413-8
    PubMed 1387614
  3. Sioud M, Natvig JB, Førre O (1992)
    Preformed ribozyme destroys tumour necrosis factor mRNA in human cells
    J Mol Biol, 223 (4), 831-5
    PubMed 1538398
  4. Waalen K, Sioud M, Natvig JB, Førre O (1992)
    Spontaneous in vivo gene transcription of interleukin-2, interleukin-3, interleukin-4, interleukin-6, interferon-gamma, interleukin-2 receptor (CD25) and proto-oncogene c-myc by rheumatoid synovial T lymphocytes
    Scand J Immunol, 36 (6), 865-73
    PubMed 1462123

Publications 1991

  1. FORTERRE P, GADELLE D, CHARBONNIER F, SIOUD M (1991)
    DNA TOPOLOGY IN HALOBACTERIA
    NATO ADV SCI INST SERIES LIFE, 201, 333-338
  2. Sioud M, Drlica K (1991)
    Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme
    Proc Natl Acad Sci U S A, 88 (16), 7303-7
    PubMed 1871136
  3. Sioud M, Førre O, Natvig JB (1991)
    T cell receptor delta diversity of freshly isolated T lymphocytes in rheumatoid synovitis
    Eur J Immunol, 21 (1), 239-41
    PubMed 1825059
  4. Sioud M, Kjeldsen-Kragh J, Quayle AJ, Wiker HG, Sørskaar D, Natvig JB, Førre O (1991)
    Immune responses to 18.6 and 30-kDa mycobacterial antigens in rheumatoid patients, and V beta usage by specific synovial T-cell lines and fresh T cells
    Scand J Immunol, 34 (6), 803-12
    PubMed 1836278

Publications 1990

  1. Pascual V, Randen I, Thompson K, Sioud M, Forre O, Natvig J, Capra JD (1990)
    The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes
    J Clin Invest, 86 (4), 1320-8
    PubMed 2170450
  2. Sioud M, Kjeldsen-Kragh J, Quayle A, Kalvenes C, Waalen K, Førre O, Natvig JB (1990)
    The V delta gene usage by freshly isolated T lymphocytes from synovial fluids in rheumatoid synovitis: a preliminary report
    Scand J Immunol, 31 (4), 415-21
    PubMed 1692153

Publications 1989

  1. Forterre P, Elie C, Sioud M, Hamal A (1989)
    Studies on DNA polymerases and topoisomerases in archaebacteria
    Can J Microbiol, 35 (1), 228-33
    PubMed 2541877
  2. Quayle A, Kjeldsen-Kragh J, Førre O, Waalen K, Sioud M, Kalvenes C, Natvig JB (1989)
    Immunoregulatory T cell subsets and T cell activation in rheumatoid arthritis. A need for analysis on the clonal and molecular level
    Springer Semin Immunopathol, 11 (3), 273-87
    PubMed 2575800
  3. Sioud M, Forterre P (1989)
    Ciprofloxacin and etoposide (VP16) produce a similar pattern of DNA cleavage in a plasmid of an archaebacterium
    Biochemistry, 28 (9), 3638-41
    PubMed 2751986

Publications 1988

  1. Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
    Novobiocin induces positive supercoiling of small plasmids from halophilic archaebacteria in vivo
    Nucleic Acids Res, 16 (4), 1379-91
    PubMed 3347494
  2. Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
    Inhibitors of DNA topoisomerase II induce topological changes in an archaebacterial plasmid in vivo
    Biochem Pharmacol, 37 (9), 1879-80
    PubMed 2837247
  3. Sioud M, Baldacci G, Forterre P, de Recondo AM (1988)
    Novobiocin induces accumulation of a single strand of plasmid pGRB-1 in the archaebacterium Halobacterium GRB
    Nucleic Acids Res, 16 (16), 7833-42
    PubMed 3419901
  4. Sioud M, Possot O, Elie C, Sibold L, Forterre P (1988)
    Coumarin and quinolone action in archaebacteria: evidence for the presence of a DNA gyrase-like enzyme
    J Bacteriol, 170 (2), 946-53
    PubMed 2828337

Publications 1987

  1. Sioud M, Baldacci G, Forterre P, de Recondo AM (1987)
    Antitumor drugs inhibit the growth of halophilic archaebacteria
    Eur J Biochem, 169 (2), 231-6
    PubMed 3121311
  2. Sioud M, Forterre P, de Recondo AM (1987)
    Effects of the antitumor drug VP16 (etoposide) on the archaebacterial Halobacterium GRB 1.7 kb plasmid in vivo
    Nucleic Acids Res, 15 (20), 8217-34
    PubMed 3671082

Publications 1986

  1. Bernard M, Sioud M, Percheron F, Foglietti MJ (1986)
    beta-Mannosidase in human serum and urine. A comparative study
    Int J Biochem, 18 (11), 1065-8
    PubMed 3803698