Experimental Radiation Therapy

 
Figure: IMRT plan showing a heterogeneous dose to the tumour according to blood flow imaging by dMRI (click to enlarge)
Figure: IMRT plan showing a heterogeneous dose to the tumour according to blood flow imaging by dMRI (click to enlarge)

Radiation therapy cures most cancer patients, next to surgery, either alone or combined with surgery. Still, approximately 1 out of 5 cancer patients die due to loco-regional failure. Radiation oncology is developing into the paradigm of focused biology, and radiobiological factors may be incorporated into optimization of radiation therapy. Late sequela is still the Achilles heel of radiation therapy, and understanding the underlying mechanisms of late toxicity is mandatory in developing strategies for enhancing the therapeutic ratio.

Our research activities aim at improving the therapeutic ratio of radiation therapy of cancers, and include studies of the radiobiological fundamental for utilizing novel irradiation technologies in improving tumour control and reducing normal tissue complications.


Read more about our current research topics:
Biological adaptive radiation therapy - BioART
Late normal tissue toxicity