Experimental Radiation Therapy

Figure: IMRT plan showing a heterogeneous dose to the tumour according to blood flow imaging by dMRI (click to enlarge)
Radiation therapy cures most cancer patients, next to surgery, either alone or combined with surgery. Still, approximately 1 out of 5 cancer patients die due to loco-regional failure. Radiation oncology is developing into the paradigm of focused biology, and radiobiological factors may be incorporated into optimization of radiation therapy. Late sequela is still the Achilles heel of radiation therapy, and understanding the underlying mechanisms of late toxicity is mandatory in developing strategies for enhancing the therapeutic ratio.
Our research activities aim at improving the therapeutic ratio of radiation therapy of cancers, and include studies of the radiobiological fundamental for utilizing novel irradiation technologies in improving tumour control and reducing normal tissue complications.
Read more about our current research topics:
Biological adaptive radiation therapy - BioART
Late normal tissue toxicity
News & events
Institute Seminar – January 18th
Christos Samakovlis: The molecular basis of airway maturation in Drosophila
Jan 17, 2012
More news
Christos Samakovlis: The molecular basis of airway maturation in Drosophila
Jan 17, 2012
Latest publications
Dag Rune Olsen
Quantification of angiogenesis in breast cancer by automated vessel identification in CD34 immunohistochemical sections
Anticancer Res, 31 (12), 4053-60
PubMed 22199261
Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenation
Int J Radiat Biol (in press)
PubMed 22132723
Liposomal doxorubicin improves radiotherapy response in hypoxic prostate cancer xenografts
Radiat Oncol, 6, 135
PubMed 21981945
More publications




Print this page
