Welcome to the Clinical Radiation Biology group!
Our goal is to develop strategies for biologically optimized radiotherapy of cancers.
To reach this goal we search for molecular biomarkers that can identify patients at risk for failure and guide the clinical decision-making, or be targets for therapeutic intervention in a combined chemoradiation regime. The basis of the research is biopsies and blood samples taken from the tumors at the time of diagnosis or during therapy. Whole genome screening methodology is used, which provides new insight into the disease and enables identification of novel biomarkers and molecular targets.
We also explore whether functional tumor images (MR/PET) can aid the translation of the molecular findings into clinical practice. The success of this strategy relies on the central role of imaging for treatment planning and monitoring in radiation oncology.
Our research projects are run in close collaboration with the clinic.
Master students are welcome to our research projects.
To reach this goal we search for molecular biomarkers that can identify patients at risk for failure and guide the clinical decision-making, or be targets for therapeutic intervention in a combined chemoradiation regime. The basis of the research is biopsies and blood samples taken from the tumors at the time of diagnosis or during therapy. Whole genome screening methodology is used, which provides new insight into the disease and enables identification of novel biomarkers and molecular targets.
We also explore whether functional tumor images (MR/PET) can aid the translation of the molecular findings into clinical practice. The success of this strategy relies on the central role of imaging for treatment planning and monitoring in radiation oncology.
Our research projects are run in close collaboration with the clinic.
Master students are welcome to our research projects.
Contact information
Heidi Lyng,
Department of Radiation Biology, Institute for Cancer Research
Norwegian Radium Hospital, Rikshospitalet University Hospital
Phone +47 22 78 1478, e-mail: heidi.lyng@rr-research.no
Heidi Lyng,
Department of Radiation Biology, Institute for Cancer Research
Norwegian Radium Hospital, Rikshospitalet University Hospital
Phone +47 22 78 1478, e-mail: heidi.lyng@rr-research.no
News & events
Institute Seminar – January 18th
Christos Samakovlis: The molecular basis of airway maturation in Drosophila
Jan 17, 2012
More news
Christos Samakovlis: The molecular basis of airway maturation in Drosophila
Jan 17, 2012
Latest PubMed articles
Dynamic contrast-enhanced MRI of cervical cancers: temporal percentile screening of contrast enhancement identifies parameters for prediction of chemoradioresistance
Int J Radiat Oncol Biol Phys, 82 (3), e485-92
PubMed 22014954
Pharmacokinetic analysis and k-means clustering of DCEMR images for radiotherapy outcome prediction of advanced cervical cancers
Acta Oncol, 50 (6), 859-65
PubMed 21767185
Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
Clin Cancer Res, 17 (16), 5501-12
PubMed 21737508
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