PubMed registered articles

Vessela N. Kristensen

Publications published since 2005 by Vessela N. Kristensen

189 publications found

Publications 2017

  1. Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
    Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
    Breast Cancer Res, 19 (1), 44
    PubMed 28356166
  2. Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN (2017)
    DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
    Oncotarget, 8 (1), 1074-1082
    PubMed 27911866
  3. Kristensen VN (2017)
    The Antigenicity of the Tumor Cell - Context Matters
    N Engl J Med, 376 (5), 491-493
    PubMed 28146670
  4. Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calléja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomäki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P et al. (2017)
    BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
    Cancer Res, 77 (11), 2789-2799
    PubMed 28283652
  5. Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlichting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen VN, Langerød A, Lundgren S, Wist EA, Naume B, Lingjerde OC, Borresen-Dale AL et al. (2017)
    The longitudinal transcriptional response to neoadjuvant chemotherapy with and without bevacizumab in breast cancer
    Clin Cancer Res (in press)
    PubMed 28487444

Publications 2016

  1. Cheng TH, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, Lewis A, French JD, Freeman-Mills L, Church D, Gorman M, Martin L, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson S, Webb PM, Australian National Endometrial Cancer Study Group (ANECS), Attia J, Holliday EG, McEvoy M, Scott RJ, Henders AK, Martin NG, Montgomery GW, Nyholt DR, Ahmed S et al. (2016)
    Five endometrial cancer risk loci identified through genome-wide association analysis
    Nat Genet, 48 (6), 667-74
    PubMed 27135401
  2. Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H, Aittomäki K, Ambrosone C, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Barile M, Barkardottir RB, Barrowdale D, Beckmann L, Beckmann MW, Benitez J, Blank SV, Blomqvist C et al. (2016)
    Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
    Nat Commun, 7, 11375
    PubMed 27117709
  3. Darabi H, Beesley J, Droit A, Kar S, Nord S, Moradi Marjaneh M, Soucy P, Michailidou K, Ghoussaini M, Fues Wahl H, Bolla MK, Wang Q, Dennis J, Alonso MR, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Broeks A, Brüning T et al. (2016)
    Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)
    Sci Rep, 6, 32512
    PubMed 27600471
  4. Demeulemeester J, Kumar P, Møller EK, Nord S, Wedge DC, Peterson A, Mathiesen RR, Fjelldal R, Zamani Esteki M, Theunis K, Fernandez Gallardo E, Grundstad AJ, Borgen E, Baumbusch LO, Børresen-Dale AL, White KP, Kristensen VN, Van Loo P, Voet T, Naume B (2016)
    Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
    Genome Biol, 17 (1), 250
    PubMed 27931250
  5. Dominguez-Valentin M, Gras Navarro A, Rahman AM, Kumar S, Retière C, Ulvestad E, Kristensen V, Lund-Johansen M, Lie BA, Enger PØ, Njølstad G, Kristoffersen E, Lie SA, Chekenya M (2016)
    Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients
    Cancer Res, 76 (18), 5326-36
    PubMed 27406829
  6. Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J et al. (2016)
    Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
    Nat Genet, 48 (4), 374-86
    PubMed 26928228
  7. Easton DF, Lesueur F, Decker B, Michailidou K, Li J, Allen J, Luccarini C, Pooley KA, Shah M, Bolla MK, Wang Q, Dennis J, Ahmad J, Thompson ER, Damiola F, Pertesi M, Voegele C, Mebirouk N, Robinot N, Durand G, Forey N, Luben RN, Ahmed S, Aittomäki K, Anton-Culver H et al. (2016)
    No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing
    J Med Genet, 53 (5), 298-309
    PubMed 26921362
  8. Eftang LL, Klajic J, Kristensen VN, Tost J, Esbensen QY, Blom GP, Bukholm IR, Bukholm G (2016)
    GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer
    BMC Cancer, 16, 225
    PubMed 26984265
  9. Espinoza JA, Jabeen S, Batra R, Papaleo E, Haakensen V, Timmermans Wielenga V, Møller Talman ML, Brunner N, Børresen-Dale AL, Gromov P, Helland Å, Kristensen VN, Gromova I (2016)
    Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
    Oncoimmunology, 5 (12), e1248015
    PubMed 28123884
  10. Ghoussaini M, French JD, Michailidou K, Nord S, Beesley J, Canisus S, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Dennis J, Bolla MK, Wang Q, Dicks E, Milne RL, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O et al. (2016)
    Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
    Am J Hum Genet, 99 (4), 903-911
    PubMed 27640304
  11. Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanova NV, Bonanni B, Børresen-Dale AL, Brand J, Brauch H et al. (2016)
    Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
    PLoS Med, 13 (8), e1002105
    PubMed 27551723
  12. Hamdi Y, Soucy P, Adoue V, Michailidou K, Canisius S, Lemaçon A, Droit A, Andrulis IL, Anton-Culver H, Arndt V, Baynes C, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borresen-Dale AL, Brand JS, Brauch H, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, NBCS Collaborators, Couch FJ et al. (2016)
    Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21
    Oncotarget, 7 (49), 80140-80163
    PubMed 27792995
  13. Horne HN, Chung CC, Zhang H, Yu K, Prokunina-Olsson L, Michailidou K, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O, Johnson N, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P, Truong T et al. (2016)
    Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus
    PLoS One, 11 (8), e0160316
    PubMed 27556229
  14. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    PubMed 27082076
  15. Kar SP, Beesley J, Amin Al Olama A, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ, ABCTB Investigators, Kibel AS, Dansonka-Mieszkowska A, Michael A, Dieffenbach AK, Gentry-Maharaj A, Whittemore AS, Wolk A, Monteiro A, Peixoto A, Kierzek A, Cox A, Rudolph A, Gonzalez-Neira A, Wu AH et al. (2016)
    Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
    Cancer Discov, 6 (9), 1052-67
    PubMed 27432226
  16. Kaveh F, Baumbusch LO, Nebdal D, Børresen-Dale AL, Lingjærde OC, Edvardsen H, Kristensen VN, Solvang HK (2016)
    A systematic comparison of copy number alterations in four types of female cancer
    BMC Cancer, 16 (1), 913
    PubMed 27876019
  17. Kleibl Z, Kristensen VN (2016)
    Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management
    Breast, 28, 136-44
    PubMed 27318168
  18. Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M et al. (2016)
    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
    Nat Commun, 7, 12675
    PubMed 27601076
  19. Lesurf R, Aure MR, Mørk HH, Vitelli V, Oslo Breast Cancer Research Consortium (OSBREAC), Lundgren S, Børresen-Dale AL, Kristensen V, Wärnberg F, Hallett M, Sørlie T (2016)
    Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
    Cell Rep, 16 (4), 1166-79
    PubMed 27396337
  20. Liu J, Lončar I, Collée JM, Bolla MK, Dennis J, Michailidou K, Wang Q, Andrulis IL, Barile M, Beckmann MW, Behrens S, Benitez J, Blomqvist C, Boeckx B, Bogdanova NV, Bojesen SE, Brauch H, Brennan P, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, Chen ST, Chenevix-Trench G, Cheng CY et al. (2016)
    rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk
    Sci Rep, 6, 36874
    PubMed 27845421
  21. Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan S, Hogervorst F, Verhoef S, Pharoah PDP, Dunning AM, Shah M, Luben R, Bojesen SE, Nordestgaard BG, Schoemaker M, Swerdlow A, García-Closas M, Figueroa J, Dörk T, Bogdanova NV, Hall P, Li J, Khusnutdinova E, Bermisheva M, Kristensen V, Borresen-Dale AL et al. (2016)
    Genetic modifiers of CHEK2*1100delC-associated breast cancer risk
    Genet Med, 19 (5), 599-603
    PubMed 27711073
  22. Painter JN, O'Mara TA, Marquart L, Webb PM, Attia J, Medland SE, Cheng T, Dennis J, Holliday EG, McEvoy M, Scott RJ, Ahmed S, Healey CS, Shah M, Gorman M, Martin L, Hodgson SV, Beckmann MW, Ekici AB, Fasching PA, Hein A, Rübner M, Czene K, Darabi H, Hall P et al. (2016)
    Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
    Cancer Epidemiol Biomarkers Prev, 25 (11), 1503-1510
    PubMed 27550749
  23. Pelttari LM, Khan S, Vuorela M, Kiiski JI, Vilske S, Nevanlinna V, Ranta S, Schleutker J, Winqvist R, Kallioniemi A, Dörk T, Bogdanova NV, Figueroa J, Pharoah PD, Schmidt MK, Dunning AM, García-Closas M, Bolla MK, Dennis J, Michailidou K, Wang Q, Hopper JL, Southey MC, Rosenberg EH, Fasching PA et al. (2016)
    RAD51B in Familial Breast Cancer
    PLoS One, 11 (5), e0153788
    PubMed 27149063
  24. Petridis C, Brook MN, Shah V, Kohut K, Gorman P, Caneppele M, Levi D, Papouli E, Orr N, Cox A, Cross SS, Dos-Santos-Silva I, Peto J, Swerdlow A, Schoemaker MJ, Bolla MK, Wang Q, Dennis J, Michailidou K, Benitez J, González-Neira A, Tessier DC, Vincent D, Li J, Figueroa J et al. (2016)
    Genetic predisposition to ductal carcinoma in situ of the breast
    Breast Cancer Res, 18 (1), 22
    PubMed 26884359
  25. Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Körner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F, Oslo Breast Cancer Research Consortium (OSBREAC)SauerTorillGeislerJürgenHofvindSolveigBathenTone FBorgenElinEngebråtenOlavFodstadØysteinGarredØysteinGeitvikGry AarumKåresenRolfNaumeBjørnMælandsmoGunhild MariRussnesHege GSchlichtingEllenSørlieThere, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Børresen-Dale AL, Yarden Y (2016)
    LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer
    EMBO Mol Med, 8 (9), 1052-64
    PubMed 27485121
  26. Schmidt MK, Hogervorst F, van Hien R, Cornelissen S, Broeks A, Adank MA, Meijers H, Waisfisz Q, Hollestelle A, Schutte M, van den Ouweland A, Hooning M, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Arndt V, Bermisheva M, Bogdanova NV, Bolla MK, Brauch H, Brenner H, Brüning T, Burwinkel B, Chang-Claude J et al. (2016)
    Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers
    J Clin Oncol, 34 (23), 2750-60
    PubMed 27269948
  27. Shi J, Zhang Y, Zheng W, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Dennis J, Lush M, Milne RL, Shu XO, Beesley J, Kar S, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Zhao Z, Guo X, Benitez J, Beeghly-Fadiel A, Blot W, Bogdanova NV, Bojesen SE, Brauch H et al. (2016)
    Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer
    Int J Cancer, 139 (6), 1303-17
    PubMed 27087578
  28. Solvang HK, Frigessi A, Kaveh F, Riis ML, Lüders T, Bukholm IR, Kristensen VN, Andreassen BK (2016)
    Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer
    EURASIP J Bioinform Syst Biol, 2016 (1), 6
    PubMed 26900390
  29. Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, Dörk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P, Tsimiklis H, Odefrey FA, Dowty JG, Schmidt MK, Broeks A et al. (2016)
    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
    J Med Genet, 53 (12), 800-811
    PubMed 27595995
  30. Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Koh KP, Mazzone M, Coleman ML, Carell T, Carmeliet P, Lambrechts D (2016)
    Tumour hypoxia causes DNA hypermethylation by reducing TET activity
    Nature, 537 (7618), 63-68
    PubMed 27533040
  31. Tinholt M, Sandset PM, Mowinckel MC, Garred Ø, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Jacobsen AF, Skretting G, Iversen N (2016)
    Determinants of acquired activated protein C resistance and D-dimer in breast cancer
    Thromb Res, 145, 78-83
    PubMed 27505249
  32. Wyszynski A, Hong CC, Lam K, Michailidou K, Lytle C, Yao S, Zhang Y, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P et al. (2016)
    An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression
    Hum Mol Genet, 25 (17), 3863-3876
    PubMed 27402876
  33. Zhao Z, Wen W, Michailidou K, Bolla MK, Wang Q, Zhang B, Long J, Shu XO, Schmidt MK, Milne RL, García-Closas M, Chang-Claude J, Lindstrom S, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Blomqvist C, Bogdanova NV, Børresen-Dale AL et al. (2016)
    Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry
    Cancer Causes Control, 27 (5), 679-93
    PubMed 27053251

Publications 2015

  1. Alnaes GI, Ronneberg JA, Kristensen VN, Tost J (2015)
    Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer
    Genes (Basel), 6 (3), 878-900
    PubMed 26393654
  2. Aure MR, Jernström S, Krohn M, Vollan HK, Due EU, Rødland E, Kåresen R, Oslo Breast Cancer Research Consortium (OSBREAC), Ram P, Lu Y, Mills GB, Sahlberg KK, Børresen-Dale AL, Lingjærde OC, Kristensen VN (2015)
    Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
    Genome Med, 7 (1), 21
    PubMed 25873999
  3. Bjørklund SS, Kristensen VN, Seiler M, Kumar S, Alnæs GI, Ming Y, Kerrigan J, Naume B, Sachidanandam R, Bhanot G, Børresen-Dale AL, Ganesan S (2015)
    Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas
    BMC Cancer, 15, 524
    PubMed 26183823
  4. Bjaanæs MM, Fleischer T, Halvorsen AR, Daunay A, Busato F, Solberg S, Jørgensen L, Kure E, Edvardsen H, Børresen-Dale AL, Brustugun OT, Tost J, Kristensen V, Helland Å (2015)
    Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
    Mol Oncol, 10 (2), 330-43
    PubMed 26601720
  5. Borge KS, Nord S, Van Loo P, Lingjærde OC, Gunnes G, Alnæs GI, Solvang HK, Lüders T, Kristensen VN, Børresen-Dale AL, Lingaas F (2015)
    Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN
    PLoS One, 10 (5), e0126371
    PubMed 25955013
  6. Cheng TH, Thompson D, Painter J, O'Mara T, Gorman M, Martin L, Palles C, Jones A, Buchanan DD, Ko Win A, Hopper J, Jenkins M, Lindor NM, Newcomb PA, Gallinger S, Conti D, Schumacher F, Casey G, Giles GG, Pharoah P, Peto J, Cox A, Swerdlow A, Couch F, Cunningham JM et al. (2015)
    Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
    Sci Rep, 5, 17369
    PubMed 26621817
  7. Darabi H, McCue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D, Ghoussaini M, Bolla MK, Dennis J, Wang Q, Canisius S, Scott CG, Apicella C, Hopper JL, Southey MC, Stone J, Broeks A, Schmidt MK, Scott RJ, Lophatananon A, Muir K, Beckmann MW, Ekici AB et al. (2015)
    Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
    Am J Hum Genet, 97 (1), 22-34
    PubMed 26073781
  8. Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM et al. (2015)
    Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
    Nat Genet, 47 (11), 1294-303
    PubMed 26414677
  9. Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM et al. (2015)
    Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT
    Obstet. Gynecol. Surv., 70 (12), 758-762
  10. Grawenda AM, Møller EK, Lam S, Repapi E, Teunisse AF, Alnæs GI, Børresen-Dale AL, Kristensen VN, Goding CR, Jochemsen AG, Edvardsen H, Bond GL (2015)
    Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer
    Cancer Res, 75 (4), 698-708
    PubMed 25649770
  11. Guo Q, Schmidt MK, Kraft P, Canisius S, Chen C, Khan S, Tyrer J, Bolla MK, Wang Q, Dennis J, Michailidou K, Lush M, Kar S, Beesley J, Dunning AM, Shah M, Czene K, Darabi H, Eriksson M, Lambrechts D, Weltens C, Leunen K, Bojesen SE, Nordestgaard BG, Nielsen SF et al. (2015)
    Identification of novel genetic markers of breast cancer survival
    J Natl Cancer Inst, 107 (5)
    PubMed 25890600
  12. Győrffy B, Bottai G, Fleischer T, Munkácsy G, Budczies J, Paladini L, Børresen-Dale AL, Kristensen VN, Santarpia L (2015)
    Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes
    Int J Cancer, 138 (1), 87-97
    PubMed 26174627
  13. Jabeen S, Holmboe L, Alnæs GI, Andersen AM, Hall KS, Kristensen VN (2015)
    Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate
    Pharmacogenomics J, 15 (5), 385-90
    PubMed 25778468
  14. Johnson KC, Koestler DC, Fleischer T, Chen P, Jenson EG, Marotti JD, Onega T, Kristensen VN, Christensen BC (2015)
    DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
    Clin Epigenetics, 7, 75
    PubMed 26213588
  15. Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, Michailidou K, Bolla MK, Wang Q, Dennis J, Shah M, Perkins BJ, Czene K, Darabi H, Eriksson M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Neven P, Peeters S, Weltens C, Couch FJ, Olson JE, Wang X, Purrington K et al. (2015)
    Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer
    Carcinogenesis, 36 (2), 256-71
    PubMed 25586992
  16. Lei J, Rudolph A, Moysich KB, Behrens S, Goode EL, Bolla MK, Dennis J, Dunning AM, Easton DF, Wang Q, Benitez J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Fasching PA, Haeberle L, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Marmé F, Guénel P, Truong T et al. (2015)
    Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium
    Hum Genet, 135 (1), 137-54
    PubMed 26621531
  17. Lei J, Rudolph A, Moysich KB, Rafiq S, Behrens S, Goode EL, Pharoah PP, Seibold P, Fasching PA, Andrulis IL, Kristensen VN, Couch FJ, Hamann U, Hooning MJ, Nevanlinna H, Eilber U, Bolla MK, Dennis J, Wang Q, Lindblom A, Mannermaa A, Lambrechts D, García-Closas M, Hall P, Chenevix-Trench G et al. (2015)
    Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
    Breast Cancer Res, 17, 18
    PubMed 25849327
  18. Mavaddat N, Pharoah PD, Michailidou K, Tyrer J, Brook MN, Bolla MK, Wang Q, Dennis J, Dunning AM, Shah M, Luben R, Brown J, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Czene K, Darabi H, Eriksson M, Peto J, Dos-Santos-Silva I, Dudbridge F, Johnson N, Schmidt MK, Broeks A et al. (2015)
    Prediction of breast cancer risk based on profiling with common genetic variants
    J Natl Cancer Inst, 107 (5)
    PubMed 25855707
  19. Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, Wang Q, Barrowdale D, Frost D, EMBRACE, McGuffog L, Ellis S, Feng B, Buys SS, Hopper JL, Southey MC, Tesoriero A, kConFab Investigators, James PA, Bruinsma F, Campbell IG, Australia Ovarian Cancer Study Group, Broeks A, Schmidt MK, Hogervorst FB, HEBON et al. (2015)
    BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
    J Natl Cancer Inst, 108 (2)
    PubMed 26586665
  20. Michailidou K, Beesley J, Lindstrom S, Canisius S, Dennis J, Lush MJ, Maranian MJ, Bolla MK, Wang Q, Shah M, Perkins BJ, Czene K, Eriksson M, Darabi H, Brand JS, Bojesen SE, Nordestgaard BG, Flyger H, Nielsen SF, Rahman N, Turnbull C, BOCS, Fletcher O, Peto J, Gibson L et al. (2015)
    Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
    Nat Genet, 47 (4), 373-80
    PubMed 25751625
  21. Nielsen HM, How-Kit A, Guerin C, Castinetti F, Vollan HK, De Micco C, Daunay A, Taieb D, Van Loo P, Besse C, Kristensen VN, Hansen LL, Barlier A, Sebag F, Tost J (2015)
    Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors
    Endocr Relat Cancer, 22 (6), 953-67
    PubMed 26400872
  22. O'Mara TA, Glubb DM, Painter JN, Cheng T, Dennis J, Australian National Endometrial Cancer Study Group (ANECS), Attia J, Holliday EG, McEvoy M, Scott RJ, Ashton K, Proietto T, Otton G, Shah M, Ahmed S, Healey CS, Gorman M, Martin L, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson S, Fasching PA, Hein A, Beckmann MW, Ekici AB, Hall P et al. (2015)
    Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
    Endocr Relat Cancer, 22 (5), 851-61
    PubMed 26330482
  23. Orr N, Dudbridge F, Dryden N, Maguire S, Novo D, Perrakis E, Johnson N, Ghoussaini M, Hopper JL, Southey MC, Apicella C, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Hogervorst FB, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Gibson L, Aitken Z, Warren H, Sawyer E, Tomlinson I et al. (2015)
    Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2
    Hum Mol Genet, 24 (10), 2966-84
    PubMed 25652398
  24. Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, and Consortium of Modifiers of BRCA1 and BRCA2, Hollestelle A, van der Baan FH, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Apicella C, Arndt V, Arnold N, Arun BK, Arver B, Ashworth A, Australian Ovarian Cancer Study Group, Baglietto L, Balleine R, Bandera EV, Barrowdale D, Bean YT et al. (2015)
    No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
    Gynecol Oncol, 141 (2), 386-401
    PubMed 25940428
  25. Pirie A, Guo Q, Kraft P, Canisius S, Eccles DM, Rahman N, Nevanlinna H, Chen C, Khan S, Tyrer J, Bolla MK, Wang Q, Dennis J, Michailidou K, Lush M, Dunning AM, Shah M, Czene K, Darabi H, Eriksson M, Lambrechts D, Weltens C, Leunen K, van Ongeval C, Nordestgaard BG et al. (2015)
    Common germline polymorphisms associated with breast cancer-specific survival
    Breast Cancer Res, 17, 58
    PubMed 25897948
  26. Potapenko IO, Lüders T, Russnes HG, Helland Å, Sørlie T, Kristensen VN, Nord S, Lingjærde OC, Børresen-Dale AL, Haakensen VD (2015)
    Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
    Mol Oncol, 9 (4), 861-76
    PubMed 25655580
  27. Quigley DA, Kristensen V (2015)
    Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells
    Mol Oncol, 9 (10), 2054-62
    PubMed 26607741
  28. Seibold P, Schmezer P, Behrens S, Michailidou K, Bolla MK, Wang Q, Flesch-Janys D, Nevanlinna H, Fagerholm R, Aittomäki K, Blomqvist C, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Lambrechts D, Wildiers H, Kristensen V, Alnæs GG, Nord S, Borresen-Dale AL, Hooning MJ, Hollestelle A, Jager A et al. (2015)
    A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients
    BMC Cancer, 15, 978
    PubMed 26674097
  29. Stone J, Thompson DJ, Dos Santos Silva I, Scott C, Tamimi RM, Lindstrom S, Kraft P, Hazra A, Li J, Eriksson L, Czene K, Hall P, Jensen M, Cunningham J, Olson JE, Purrington K, Couch FJ, Brown J, Leyland J, Warren RM, Luben RN, Khaw KT, Smith P, Wareham NJ, Jud SM et al. (2015)
    Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures
    Cancer Res, 75 (12), 2457-67
    PubMed 25862352
  30. Thompson DJ, O'Mara TA, Glubb DM, Painter JN, Cheng T, Folkerd E, Doody D, Dennis J, Webb PM, Australian National Endometrial Cancer Study Group (ANECS), Gorman M, Martin L, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), Michailidou K, Tyrer JP, Maranian MJ, Hall P, Czene K, Darabi H, Li J, Fasching PA, Hein A, Beckmann MW, Ekici AB et al. (2015)
    CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer
    Endocr Relat Cancer, 23 (2), 77-91
    PubMed 26574572
  31. Tinholt M, Vollan HK, Sahlberg KK, Jernström S, Kaveh F, Lingjærde OC, Kåresen R, Sauer T, Kristensen V, Børresen-Dale AL, Sandset PM, Iversen N (2015)
    Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
    Breast Cancer Res, 17, 44
    PubMed 25882602
  32. Zhang B, Shu XO, Delahanty RJ, Zeng C, Michailidou K, Bolla MK, Wang Q, Dennis J, Wen W, Long J, Li C, Dunning AM, Chang-Claude J, Shah M, Perkins BJ, Czene K, Darabi H, Eriksson M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Neven P, Wildiers H et al. (2015)
    Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization
    J Natl Cancer Inst, 107 (11)
    PubMed 26296642

Publications 2014

  1. Carvajal-Carmona LG, O'Mara TA, Painter JN, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Pooley K, Beesley J, Cheng T, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), Australian National Endometrial Cancer Study Group (ANECS), Wentzensen N, Fasching PA, Hein A, Beckmann MW, Renner SP et al. (2014)
    Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
    Hum Genet, 134 (2), 231-45
    PubMed 25487306
  2. Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K et al. (2014)
    Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers
    Cancer Cell, 26 (6), 863-79
    PubMed 25490449
  3. Fleischer T, Edvardsen H, Solvang HK, Daviaud C, Naume B, Børresen-Dale AL, Kristensen VN, Tost J (2014)
    Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients
    Int J Cancer, 134 (11), 2615-25
    PubMed 24395279
  4. Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
    Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
    Genome Biol, 15 (8), 435
    PubMed 25146004
  5. Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE et al. (2014)
    Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
    Nat Commun, 4, 4999
    PubMed 25248036
  6. Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O'Reilly M, Betts JA, Hillman KM, Kaufmann S, Beesley J, Canisius S, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Schmidt MK, Broeks A, Hogervorst FB, van der Schoot CE, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P et al. (2014)
    Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1
    Am J Hum Genet, 96 (1), 5-20
    PubMed 25529635
  7. Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
    Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
    Int J Cancer, 135 (9), 2085-95
    PubMed 24658971
  8. Johnson N, Dudbridge F, Orr N, Gibson L, Jones ME, Schoemaker MJ, Folkerd EJ, Haynes BP, Hopper JL, Southey MC, Dite GS, Apicella C, Schmidt MK, Broeks A, Van't Veer LJ, Atsma F, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Ekici AB, Renner SP, Sawyer E, Tomlinson I, Kerin M et al. (2014)
    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study
    Breast Cancer Res, 16 (3), R51
    PubMed 24887515
  9. Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I, Johnson N, Gibson L et al. (2014)
    MicroRNA related polymorphisms and breast cancer risk
    PLoS One, 9 (11), e109973
    PubMed 25390939
  10. Klajic J, Busato F, Edvardsen H, Touleimat N, Fleischer T, Bukholm I, Børresen-Dale AL, Lønning PE, Tost J, Kristensen VN (2014)
    DNA methylation status of key cell-cycle regulators such as CDKNA2/p16 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors
    Clin Cancer Res, 20 (24), 6357-66
    PubMed 25294903
  11. Kristensen VN, Lingjærde OC, Russnes HG, Vollan HK, Frigessi A, Børresen-Dale AL (2014)
    Principles and methods of integrative genomic analyses in cancer
    Nat Rev Cancer, 14 (5), 299-313
    PubMed 24759209
  12. Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, Michailidou K, Dennis J, Bolla MK, Wang Q, Van 't Veer LJ, Cornelissen S, Rutgers E, Southey MC, Apicella C, Dite GS, Hopper JL, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Blomqvist C, Muranen TA, Aittomäki K, Lindblom A et al. (2014)
    2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
    Nat Commun, 5, 4051
    PubMed 24937182
  13. Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N et al. (2014)
    Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
    Hum Mol Genet, 24 (1), 285-98
    PubMed 25168388
  14. Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Kaufmann S, Hillman KM, Walpole C, Moya L, Pollock P, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), CHIBCHA Consortium, De Polanco MM, Sans M et al. (2014)
    Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
    Hum Mol Genet, 24 (5), 1478-92
    PubMed 25378557
  15. Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, Guénel P, Meindl A, Darabi H et al. (2014)
    Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
    Hum Mol Genet, 23 (22), 6034-46
    PubMed 24927736
  16. Quigley D, Silwal-Pandit L, Dannenfelser R, Langerød A, Vollan HK, Vaske C, Siegel JU, Troyanskaya O, Chin SF, Caldas C, Balmain A, Børresen-Dale AL, Kristensen V (2014)
    Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53
    Mol Cancer Res, 13 (3), 493-501
    PubMed 25351767
  17. Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO (2014)
    Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes
    PLoS One, 9 (9), e106076
    PubMed 25264628
  18. Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hopper JL, Provenzano E et al. (2014)
    Genetic predisposition to in situ and invasive lobular carcinoma of the breast
    PLoS Genet, 10 (4), e1004285
    PubMed 24743323
  19. Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, Quigley DA, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Langerød A (2014)
    TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
    Clin Cancer Res, 20 (13), 3569-80
    PubMed 24803582
  20. Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
    Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
    BMC Cancer, 14, 845
    PubMed 25407022
  21. Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN, METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C (2014)
    A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
    Mol Oncol, 9 (1), 115-27
    PubMed 25169931
  22. Zhao X, Rødland EA, Sørlie T, Vollan HK, Russnes HG, Kristensen VN, Lingjærde OC, Børresen-Dale AL (2014)
    Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
    BMC Cancer, 14, 211
    PubMed 24645668

Publications 2013

  1. Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
    Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
    Genome Biol, 14 (11), R126
    PubMed 24257477
  2. Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
    Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
    PLoS One, 8 (1), e53014
    PubMed 23382830
  3. Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
    Improving breast cancer survival analysis through competition-based multidimensional modeling
    PLoS Comput Biol, 9 (5), e1003047
    PubMed 23671412
  4. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
    Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
    Nat Genet, 45 (4), 371-84, 384e1-2
    PubMed 23535731
  5. Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
    SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
    Int J Radiat Oncol Biol Phys, 86 (4), 791-9
    PubMed 23597419
  6. French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
    Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
    Am J Hum Genet, 92 (4), 489-503
    PubMed 23540573
  7. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
    Genome-wide association studies identify four ER negative-specific breast cancer risk loci
    Nat Genet, 45 (4), 392-8, 398e1-2
    PubMed 23535733
  8. Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
    Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
    BMC Cancer, 13, 456
    PubMed 24093668
  9. Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
    Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
    Genomics, 102 (4), 278-87
    PubMed 23880221
  10. Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
    Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
    J Med Genet, 50 (10), 666-73
    PubMed 23825393
  11. Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
    Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
    Sci Transl Med, 5 (181), 181re1
    PubMed 23596205
  12. Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
    Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
    Am J Hum Genet, 93 (6), 1046-60
    PubMed 24290378
  13. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
    Large-scale genotyping identifies 41 new loci associated with breast cancer risk
    Nat Genet, 45 (4), 353-61, 361e1-2
    PubMed 23535729
  14. Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
    A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
    Hum Mol Genet, 23 (7), 1934-46
    PubMed 24242184
  15. Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
    Next-generation sequencing of disseminated tumor cells
    Front Oncol, 3, 320
    PubMed 24427740
  16. Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
    Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
    Carcinogenesis, 35 (5), 1012-9
    PubMed 24325915
  17. Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
    The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
    Mol Oncol, 8 (2), 273-84
    PubMed 24388359
  18. Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
    Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
    ISRN Oncol, 2013, 924971
    PubMed 23533813
  19. Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
    Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
    Carcinogenesis, 35 (1), 76-85
    PubMed 24104550
  20. Tahiri A, Røe K, Ree AH, de Wijn R, Risberg K, Busch C, Lønning PE, Kristensen V, Geisler J (2013)
    Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma
    PLoS One, 8 (8), e72692
    PubMed 24023633

Publications 2012

  1. Engebraaten O, Edvardsen H, Løkkevik E, Naume B, Kristensen V, Ottestad L, Natarajan V (2012)
    Gefitinib in Combination with Weekly Docetaxel in Patients with Metastatic Breast Cancer Caused Unexpected Toxicity: Results from a Randomized Phase II Clinical Trial
    ISRN Oncol, 2012, 176789
    PubMed 22666610
  2. Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang Q, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Hall P, Czene K et al. (2012)
    Genome-wide association analysis identifies three new breast cancer susceptibility loci
    Nat Genet, 44 (3), 312-8
    PubMed 22267197
  3. Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FB, Bueno-de-Mesquita HB, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Fasching PA, Hein A, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Sawyer E, Tomlinson I, Kerin M et al. (2012)
    Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)
    PLoS One, 7 (8), e42380
    PubMed 22879957
  4. Joshi H, Bhanot G, Børresen-Dale AL, Kristensen V (2012)
    Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
    Br J Cancer, 107 (10), 1722-8
    PubMed 23079576
  5. Joshi H, Nord SH, Frigessi A, Børresen-Dale AL, Kristensen VN (2012)
    Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
    BMC Genomics, 13, 199
    PubMed 22616941
  6. Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C, Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JI, Benítez J, Hamann U, Ko YD, Brüning T, GENICA Network et al. (2012)
    11q13 is a susceptibility locus for hormone receptor positive breast cancer
    Hum Mutat, 33 (7), 1123-32
    PubMed 22461340
  7. Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR (2012)
    Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes
    ISRN Oncol, 2012, 450267
    PubMed 23227362
  8. Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, GENICA Network, Ko YD, Fischer HP, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C et al. (2012)
    19p13.1 is a triple-negative-specific breast cancer susceptibility locus
    Cancer Res, 72 (7), 1795-803
    PubMed 22331459
  9. Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C, Odefrey F, Gierach GL, Jud SM, Heusinger K, Beckmann MW, Pollan M, Fernández-Navarro P, Gonzalez-Neira A, Benitez J, van Gils CH, Lokate M, Onland-Moret NC, Peeters PH, Brown J, Leyland J, Varghese JS, Easton DF et al. (2012)
    Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk
    Cancer Epidemiol Biomarkers Prev, 21 (7), 1156-66
    PubMed 22454379
  10. Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adamek J, Edvardsen H, Kristensen VN, Gut I, Soucek P (2012)
    Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis
    Clin Chem Lab Med, 50 (11), 1999-2007
    PubMed 23093106
  11. Van Loo P, Nilsen G, Nordgard SH, Vollan HK, Børresen-Dale AL, Kristensen VN, Lingjærde OC (2012)
    Analyzing cancer samples with SNP arrays
    Methods Mol Biol, 802, 57-72
    PubMed 22130873
  12. Weischer M, Nordestgaard BG, Pharoah P, Bolla MK, Nevanlinna H, Van't Veer LJ, Garcia-Closas M, Hopper JL, Hall P, Andrulis IL, Devilee P, Fasching PA, Anton-Culver H, Lambrechts D, Hooning M, Cox A, Giles GG, Burwinkel B, Lindblom A, Couch FJ, Mannermaa A, Grenaker Alnæs G, John EM, Dörk T, Flyger H et al. (2012)
    CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer
    J Clin Oncol, 30 (35), 4308-16
    PubMed 23109706

Publications 2011

  1. Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C et al. (2011)
    Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
    Hum Mol Genet, 20 (16), 3289-303
    PubMed 21596841
  2. Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, Rønneberg JA, Johnsen H, Navon R, Rødland E, Mäkelä R, Naume B, Perälä M, Kallioniemi O, Kristensen VN, Yakhini Z, Børresen-Dale AL (2011)
    miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
    PLoS One, 6 (2), e16915
    PubMed 21364938
  3. Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
    Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
    BMC Cancer, 11, 332
    PubMed 21812955
  4. Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
    Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
    BMC Med Genomics, 4, 77
    PubMed 22044755
  5. Kristensen VN (2011)
    Divide and conquer: the genetic basis of molecular subclassification of breast cancer
    EMBO Mol Med, 3 (4), 183-5
    PubMed 21394915
  6. Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
    Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
    Proc Natl Acad Sci U S A, 109 (8), 2802-7
    PubMed 21908711
  7. Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Arias Pérez JI, Benítez J, Dörk T, Schürmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliot G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC et al. (2011)
    Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
    Cancer Epidemiol Biomarkers Prev, 20 (10), 2222-31
    PubMed 21795498
  8. Reinertsen KV, Grenaker Alnæs GI, Landmark-Høyvik H, Loge JH, Wist E, Kristensen VN, Fosså SD, Edvardsen H (2011)
    Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway
    Brain Behav Immun, 25 (7), 1376-83
    PubMed 21496483
  9. Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
    Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
    BMC Bioinformatics, 12, 197
    PubMed 21609452
  10. Weigman VJ, Chao HH, Shabalin AA, He X, Parker JS, Nordgard SH, Grushko T, Huo D, Nwachukwu C, Nobel A, Kristensen VN, Børresen-Dale AL, Olopade OI, Perou CM (2011)
    Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Breast Cancer Res Treat, 133 (3), 865-80
    PubMed 22048815
  11. Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
    Combining gene signatures improves prediction of breast cancer survival
    PLoS One, 6 (3), e17845
    PubMed 21423775

Publications 2010

  1. Biong M, Gram IT, Brill I, Johansen F, Solvang HK, Alnaes GI, Fagerheim T, Bremnes Y, Chanock SJ, Burdett L, Yeager M, Ursin G, Kristensen VN (2010)
    Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
    BMC Med Genomics, 3, 9
    PubMed 20302654
  2. Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
    On the molecular biology of breast cancer
    Mol Oncol, 4 (3), 171-3
    PubMed 20483673
  3. Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J (2010)
    DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
    Mol Cancer, 9, 68
    PubMed 20338046
  4. Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
    SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
    Pharmacogenomics J, 10 (6), 513-23
    PubMed 20157331
  5. Fu YP, Edvardsen H, Kaushiva A, Arhancet JP, Howe TM, Kohaar I, Porter-Gill P, Shah A, Landmark-Høyvik H, Fosså SD, Ambs S, Naume B, Børresen-Dale AL, Kristensen VN, Prokunina-Olsson L (2010)
    NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
    Mol Cancer, 9, 113
    PubMed 20482849
  6. Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
    Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
    Breast Cancer Res, 12 (4), R65
    PubMed 20799965
  7. Jovanovic J, Rønneberg JA, Tost J, Kristensen V (2010)
    The epigenetics of breast cancer
    Mol Oncol, 4 (3), 242-54
    PubMed 20627830
  8. Kristensen V, Borresen-Dale AL (2010)
    Mutations for the people
    EMBO Mol Med, 2 (5), 143-5
    PubMed 20461736
  9. Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
    The genetics and epigenetics of fatigue
    PM R, 2 (5), 456-65
    PubMed 20656628
  10. Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
    Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
    Breast Cancer Res, 12 (1), R3
    PubMed 20056007
  11. Pedersen RS, Brasch-Andersen C, Sim SC, Bergmann TK, Halling J, Petersen MS, Weihe P, Edvardsen H, Kristensen VN, Brøsen K, Ingelman-Sundberg M (2010)
    Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
    Eur J Clin Pharmacol, 66 (12), 1199-205
    PubMed 20665013
  12. Riis ML, Lüders T, Nesbakken AJ, Vollan HS, Kristensen V, Bukholm IR (2010)
    Expression of BMI-1 and Mel-18 in breast tissue--a diagnostic marker in patients with breast cancer
    BMC Cancer, 10, 686
    PubMed 21162745
  13. Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V (2010)
    Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
    Mol Oncol, 5 (1), 61-76
    PubMed 21212030
  14. Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN (2010)
    Allele-specific copy number analysis of tumors
    Proc Natl Acad Sci U S A, 107 (39), 16910-5
    PubMed 20837533

Publications 2009

  1. Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S, EPIC, Haiman CA, Le Marchand L, MEC, Broeks A, Schmidt MK, ABCS, Hopper J, Southey M, ABCFS, Beckmann MW, Fasching PA, BBCC et al. (2009)
    Association of ESR1 gene tagging SNPs with breast cancer risk
    Hum Mol Genet, 18 (6), 1131-9
    PubMed 19126777
  2. Gaudet MM, Milne RL, Cox A, Camp NJ, Goode EL, Humphreys MK, Dunning AM, Morrison J, Giles GG, Severi G, Baglietto L, English DR, Couch FJ, Olson JE, Wang X, Chang-Claude J, Flesch-Janys D, Abbas S, Salazar R, Mannermaa A, Kataja V, Kosma VM, Lindblom A, Margolin S, Heikkinen T et al. (2009)
    Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Cancer Epidemiol Biomarkers Prev, 18 (5), 1610-6
    PubMed 19423537
  3. Glynn SA, Boersma BJ, Howe TM, Edvardsen H, Geisler SB, Goodman JE, Ridnour LA, Lønning PE, Børresen-Dale AL, Naume B, Kristensen VN, Chanock SJ, Wink DA, Ambs S (2009)
    A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
    Clin Cancer Res, 15 (12), 4165-73
    PubMed 19509150
  4. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
    Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
    Pharmacogenet Genomics, 19 (10), 751-9
    PubMed 19741569
  5. Leivonen SK, Mäkelä R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, Enerly E, Aakula A, Hellström K, Sahlberg N, Kristensen VN, Børresen-Dale AL, Saviranta P, Perälä M, Kallioniemi O (2009)
    Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
    Oncogene, 28 (44), 3926-36
    PubMed 19684618
  6. Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
    Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
    Mol Oncol, 4 (2), 98-118
    PubMed 20060370
  7. Sun W, Wright FA, Tang Z, Nordgard SH, Van Loo P, Yu T, Kristensen VN, Perou CM (2009)
    Integrated study of copy number states and genotype calls using high-density SNP arrays
    Nucleic Acids Res, 37 (16), 5365-77
    PubMed 19581427

Publications 2008

  1. Baumbusch LO, Aarøe J, Johansen FE, Hicks J, Sun H, Bruhn L, Gunderson K, Naume B, Kristensen VN, Liestøl K, Børresen-Dale AL, Lingjaerde OC (2008)
    Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    BMC Genomics, 9, 379
    PubMed 18691401
  2. Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
    Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
    Breast Cancer Res, 10 (1), R13
    PubMed 18271962
  3. Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC, Kristensen VN, Børresen-Dale AL, Pollack J, van de Vijver MJ (2008)
    ESR1 gene amplification in breast cancer: a common phenomenon?
    Nat Genet, 40 (7), 807-8; author reply 810-2
    PubMed 18583965
  4. Kristensen VN, Børresen-Dale AL (2008)
    SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
    Mol Oncol, 2 (1), 12-5
    PubMed 19383324
  5. Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
    Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
    Genet Epidemiol, 32 (2), 168-78
    PubMed 17968987
  6. Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
    Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
    Int J Cancer, 123 (3), 577-85
    PubMed 18498133
  7. Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN (2008)
    Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
    Genes Chromosomes Cancer, 47 (8), 680-96
    PubMed 18398821
  8. Rønneberg JA, Tost J, Solvang HK, Alnaes GI, Johansen FE, Brendeford EM, Yakhini Z, Gut IG, Lønning PE, Børresen-Dale AL, Gabrielsen OS, Kristensen VN (2008)
    GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
    Cancer Res, 68 (14), 5562-71
    PubMed 18632608
  9. Tongbai R, Idelman G, Nordgard SH, Cui W, Jacobs JL, Haggerty CM, Chanock SJ, Børresen-Dale AL, Livingston G, Shaunessy P, Chiang CH, Kristensen VN, Bilke S, Gardner K (2008)
    Transcriptional networks inferred from molecular signatures of breast cancer
    Am J Pathol, 172 (2), 495-509
    PubMed 18187569
  10. Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P (2008)
    Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients
    Pharmacogenet Genomics, 18 (3), 263-73
    PubMed 18300948

Publications 2007

  1. Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
    Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
    BMC Cancer, 7, 197
    PubMed 17956601
  2. Chanock SJ, Burdett L, Yeager M, Llaca V, Langerød A, Presswalla S, Kaaresen R, Strausberg RL, Gerhard DS, Kristensen V, Perou CM, Børresen-Dale AL (2007)
    Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
    Breast Cancer Res, 9 (1), R5
    PubMed 17224074
  3. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
    Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
    Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
    PubMed 17336217
  4. Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL (2007)
    Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
    Radiat Oncol, 2, 25
    PubMed 17623063
  5. Garcia-Closas M, Kristensen V, Langerød A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Børresen-Dale AL, Chanock S (2007)
    Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
    Int J Cancer, 121 (11), 2532-8
    PubMed 17683073
  6. Garcia-Closas M, Troester MA, Qi Y, Langerød A, Yeager M, Lissowska J, Brinton L, Welch R, Peplonska B, Gerhard DS, Gram IT, Kristensen V, Børresen-Dale AL, Chanock S, Perou CM (2007)
    Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
    Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
    PubMed 18006915
  7. Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E (2007)
    Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (11), 1221-30
    PubMed 17404387
  8. Nordgard SH, Johansen FE, Alnaes GI, Naume B, Børresen-Dale AL, Kristensen VN (2007)
    Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
    Breast Cancer Res, 9 (6), 113
    PubMed 18036273
  9. Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN (2007)
    ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
    Pharmacogenet Genomics, 17 (2), 127-36
    PubMed 17301692
  10. Roca X, Olson AJ, Rao AR, Enerly E, Kristensen VN, Børresen-Dale AL, Andresen BS, Krainer AR, Sachidanandam R (2007)
    Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
    Genome Res, 18 (1), 77-87
    PubMed 18032726
  11. Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R (2007)
    A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
    Bioinformatics, 23 (2), e91-8
    PubMed 17237111

Publications 2006

  1. Edvardsen H, Irene Grenaker Alnaes G, Tsalenko A, Mulcahy T, Yuryev A, Lindersson M, Lien S, Omholt S, Syvänen AC, Børresen-Dale AL, Kristensen VN (2006)
    Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
    Pharmacogenet Genomics, 16 (3), 207-17
    PubMed 16495780
  2. Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
    Genetic variation in putative regulatory loci controlling gene expression in breast cancer
    Proc Natl Acad Sci U S A, 103 (20), 7735-40
    PubMed 16684880
  3. Kristensen VN, Tsalenko A, Geisler J, Faldaas A, Grenaker GI, Lingjaerde OC, Fjeldstad S, Yakhini Z, Lønning PE, Børresen-Dale AL (2006)
    Multilocus analysis of SNP and metabolic data within a given pathway
    BMC Genomics, 7, 5
    PubMed 16412218
  4. Lahermo P, Liljedahl U, Alnaes G, Axelsson T, Brookes AJ, Ellonen P, Groop PH, Halldén C, Holmberg D, Holmberg K, Keinänen M, Kepp K, Kere J, Kiviluoma P, Kristensen V, Lindgren C, Odeberg J, Osterman P, Parkkonen M, Saarela J, Sterner M, Strömqvist L, Talas U, Wessman M, Palotie A et al. (2006)
    A quality assessment survey of SNP genotyping laboratories
    Hum Mutat, 27 (7), 711-4
    PubMed 16786507
  5. Paracchini V, Raimondi S, Gram IT, Kang D, Kocabas NA, Kristensen VN, Li D, Parl FF, Rylander-Rudqvist T, Soucek P, Zheng W, Wedren S, Taioli E (2006)
    Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (2), 115-25
    PubMed 17053044
  6. Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE (2006)
    The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
    Clin Cancer Res, 12 (20 Pt 1), 6000-4
    PubMed 17062672
  7. Tommiska J, Jansen L, Kilpivaara O, Edvardsen H, Kristensen V, Tamminen A, Aittomäki K, Blomqvist C, Børresen-Dale AL, Nevanlinna H (2006)
    ATM variants and cancer risk in breast cancer patients from Southern Finland
    BMC Cancer, 6, 209
    PubMed 16914028
  8. Tsalenko A, Sharan R, Kristensen V, Edvardsen H, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2006)
    Analysis of SNP-expression association matrices
    J Bioinform Comput Biol, 4 (2), 259-74
    PubMed 16819783

Publications 2005

  1. Come SE, Buzdar AU, Ingle JN, Arteaga CL, Brodie AM, Colditz GA, Johnston SR, Kristensen VN, Lønning PE, McDonnell DP, Osborne CK, Russo J, Santen RJ, Yee D, Hart CS (2005)
    Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
    Clin Cancer Res, 11 (2 Pt 2), 861s-4s
    PubMed 15701878
  2. Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
    Clin Cancer Res, 11 (2 Pt 2), 878s-83s
    PubMed 15701881
  3. Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
    J Steroid Biochem Mol Biol, 95 (1-5), 105-11
    PubMed 16023338
  4. Tsalenko A, Sharan R, Edvardsen H, Kristensen V, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2005)
    Analysis of SNP-expression association matrices
    Proc IEEE Comput Syst Bioinform Conf, 135-43
    PubMed 16447971