Scientific projects

Author network for Erik Øie by COREMINE medical

Publications in press

Beitnes JO, Oie E, Shahdadfar A, Karlsen T, Müller RM, Aakhus S, Reinholt FP, Brinchmann JE
Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular function
Cell Transplant (in press)
PubMed 22410280

Publications 2012

Sikkeland LI, Dahl CP, Ueland T, Andreassen AK, Gude E, Edvardsen T, Holm T, Yndestad A, Gullestad L, Kongerud J, Aukrust P, Oie E (2012)
Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure
PLoS One, 7 (5), e36815
PubMed 22615818

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P (2012)
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
PubMed 22427939

Publications 2011

Ahmed MS, Gravning J, Martinov VN, von Lueder TG, Edvardsen T, Czibik G, Moe IT, Vinge LE, Øie E, Valen G, Attramadal H (2011)
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol, 300 (4), H1291-302
PubMed 21186275

Andersen GØ, Knudsen EC, Aukrust P, Yndestad A, Oie E, Müller C, Seljeflot I, Ueland T (2011)
Elevated serum osteoprotegerin levels measured early after acute ST-elevation myocardial infarction predict final infarct size
Heart, 97 (6), 460-5
PubMed 21270073

Fosshaug LE, Berge RK, Beitnes JO, Berge K, Vik H, Aukrust P, Gullestad L, Vinge LE, Øie E (2011)
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
Lipids Health Dis, 10, 245
PubMed 22206454

Øie E, Ueland T, Dahl CP, Bohov P, Berge C, Yndestad A, Gullestad L, Aukrust P, Berge RK (2011)
Fatty acid composition in chronic heart failure: low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality
J Intern Med, 270 (3), 263-72
PubMed 21466599

Publications 2010

Bergestuen DS, Edvardsen T, Aakhus S, Ueland T, Oie E, Vatn M, Aukrust P, Thiis-Evensen E (2010)
Activin A in carcinoid heart disease: a possible role in diagnosis and pathogenesis
Neuroendocrinology, 92 (3), 168-77
PubMed 20720391

Bergestuen DS, Gravning J, Haugaa KH, Sahakyan LG, Aakhus S, Thiis-Evensen E, Øie E, Aukrust P, Attramadal H, Edvardsen T (2010)
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
PubMed 20053285

Breland UM, Michelsen AE, Skjelland M, Folkersen L, Krohg-Sørensen K, Russell D, Ueland T, Yndestad A, Paulsson-Berne G, Damås JK, Oie E, Hansson GK, Halvorsen B, Aukrust P (2010)
Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation
Cardiovasc Res, 86 (2), 265-73
PubMed 20139115

Michelsen AE, Rathcke CN, Skjelland M, Holm S, Ranheim T, Krohg-Sørensen K, Klingvall MF, Brosstad F, Oie E, Vestergaard H, Aukrust P, Halvorsen B (2010)
Increased YKL-40 expression in patients with carotid atherosclerosis
Atherosclerosis, 211 (2), 589-95
PubMed 20347092

Røsjø H, Husberg C, Dahl MB, Stridsberg M, Sjaastad I, Finsen AV, Carlson CR, Oie E, Omland T, Christensen G (2010)
Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium
Circ Heart Fail, 3 (4), 503-11
PubMed 20519641

Øie E, Ahmed MS, Ueland T, Sikkeland LI, Dahl CP, Hagelin EM, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H (2010)
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res Cardiol, 105 (1), 89-98
PubMed 19823891

Øie E, Sandberg WJ, Ahmed MS, Yndestad A, Lærum OD, Attramadal H, Aukrust P, Eiken HG (2010)
Activation of Notch signaling in cardiomyocytes during post-infarction remodeling
Scand Cardiovasc J, 44 (6), 359-66
PubMed 20799913

Publications 2009

Dahl CP, Husberg C, Gullestad L, Waehre A, Damås JK, Vinge LE, Finsen AV, Ueland T, Florholmen G, Aakhus S, Halvorsen B, Aukrust P, Oie E, Yndestad A, Christensen G (2009)
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
PubMed 19919988

Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Frøland SS, Olofsson PS, Damås JK, Gullestad L, Hansson GK, Oie E, Aukrust P (2009)
Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis
Circ Res, 104 (1), 60-8
PubMed 19023130

Sandberg WJ, Otterdal K, Gullestad L, Halvorsen B, Ragnarsson A, Frøland SS, Damås JK, Oie E, Aukrust P, Hansson GK, Yndestad A (2009)
The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis
Thromb Haemost, 102 (4), 704-10
PubMed 19806256

Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg WJ, Paulsson-Berne G, Pedersen TM, Folkersen L, Gullestad L, Oie E, Hansson GK, Aukrust P (2009)
Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Arterioscler Thromb Vasc Biol, 29 (8), 1228-34
PubMed 19498175

Yndestad A, Landrø L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Frøland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Øie E, Gullestad L, Aukrust P (2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
PubMed 19329498

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjønsberg OH, Pedersen TM, Anfinsen OG, Damås JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol, 106 (4), 1356-64
PubMed 19196915

Yndestad A, Neurauter CG, Oie E, Forstrøm RJ, Vinge LE, Eide L, Luna L, Aukrust P, Bjørås M (2009)
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure
Mutat Res, 666 (1-2), 32-8
PubMed 19481677

Publications 2008

Aukrust P, Halvorsen B, Yndestad A, Ueland T, Øie E, Otterdal K, Gullestad L, Damås JK (2008)
Chemokines and cardiovascular risk
Arterioscler Thromb Vasc Biol, 28 (11), 1909-19
PubMed 18669888

Aukrust P, Otterdal K, Yndestad A, Sandberg WJ, Smith C, Ueland T, Øie E, Damås JK, Gullestad L, Halvorsen B (2008)
The complex role of T-cell-based immunity in atherosclerosis
Curr Atheroscler Rep, 10 (3), 236-43
PubMed 18489852

Breland UM, Halvorsen B, Hol J, Øie E, Paulsson-Berne G, Yndestad A, Smith C, Otterdal K, Hedin U, Waehre T, Sandberg WJ, Frøland SS, Haraldsen G, Gullestad L, Damås JK, Hansson GK, Aukrust P (2008)
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
PubMed 18276907

Dahl CP, Gullestad L, Fevang B, Holm AM, Landrø L, Vinge LE, Fiane AE, Sandberg WJ, Otterdal K, Frøland SS, Damås JK, Halvorsen B, Aukrust P, Øie E, Yndestad A (2008)
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
PubMed 18353719

Halvorsen B, Otterdal K, Dahl TB, Skjelland M, Gullestad L, Øie E, Aukrust P (2008)
Atherosclerotic plaque stability--what determines the fate of a plaque?
Prog Cardiovasc Dis, 51 (3), 183-94
PubMed 19026853

Handberg A, Skjelland M, Michelsen AE, Sagen EL, Krohg-Sørensen K, Russell D, Dahl A, Ueland T, Oie E, Aukrust P, Halvorsen B (2008)
Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability
Stroke, 39 (11), 3092-5
PubMed 18723424

Husberg C, Nygård S, Finsen AV, Damås JK, Frigessi A, Oie E, Waehre A, Gullestad L, Aukrust P, Yndestad A, Christensen G (2008)
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure
J Mol Cell Cardiol, 45 (2), 261-9
PubMed 18585734

Otterdal K, Andreassen AK, Yndestad A, Oie E, Sandberg WJ, Dahl CP, Pedersen TM, Ueland T, Gullestad L, Brosstad FR, Aukrust P, Damås JK (2008)
Raised LIGHT levels in pulmonary arterial hypertension: potential role in thrombus formation
Am J Respir Crit Care Med, 177 (2), 202-7
PubMed 17962639

Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P (2008)
Endothelial S100A1 modulates vascular function via nitric oxide
Circ Res, 102 (7), 786-94
PubMed 18292599

Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Frøland SS, Oie E, Gullestad L, Damås JK, Aukrust P (2008)
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins
Cardiovasc Res, 79 (1), 195-203
PubMed 18339644

Vinge LE, von Lueder TG, Aasum E, Qvigstad E, Gravning JA, How OJ, Edvardsen T, Bjørnerheim R, Ahmed MS, Mikkelsen BW, Oie E, Attramadal T, Skomedal T, Smiseth OA, Koch WJ, Larsen TS, Attramadal H (2008)
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness
J Biol Chem, 283 (16), 10601-10
PubMed 18165681

Publications 2007

Ahmed MS, Øie E, Vinge LE, von Lueder TG, Attramadal T, Attramadal H (2007)
Induction of pulmonary connective tissue growth factor in heart failure is associated with pulmonary parenchymal and vascular remodeling
Cardiovasc Res, 74 (2), 323-33
PubMed 17254558

Aukrust P, Yndestad A, Damås JK, Ueland T, Øie E, Gullestad L (2007)
Potential mechanisms of benefit with thalidomide in chronic heart failure
Am J Cardiovasc Drugs, 7 (2), 127-34
PubMed 17503883

Dahl TB, Yndestad A, Skjelland M, Øie E, Dahl A, Michelsen A, Damås JK, Tunheim SH, Ueland T, Smith C, Bendz B, Tonstad S, Gullestad L, Frøland SS, Krohg-Sørensen K, Russell D, Aukrust P, Halvorsen B (2007)
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization
Circulation, 115 (8), 972-80
PubMed 17283255

Damås JK, Smith C, Øie E, Fevang B, Halvorsen B, Waehre T, Boullier A, Breland U, Yndestad A, Ovchinnikova O, Robertson AK, Sandberg WJ, Kjekshus J, Taskén K, Frøland SS, Gullestad L, Hansson GK, Quehenberger O, Aukrust P (2007)
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Arterioscler Thromb Vasc Biol, 27 (3), 614-20
PubMed 17170367

Gullestad L, Oie E, Ueland T, Yndestad A, Aukrust P (2007)
The role of statins in heart failure
Fundam Clin Pharmacol, 21 Suppl 2, 35-40
PubMed 18001320

Yndestad A, Damås JK, Øie E, Ueland T, Gullestad L, Aukrust P (2007)
Role of inflammation in the progression of heart failure
Curr Cardiol Rep, 9 (3), 236-41
PubMed 17470337

Publications 2006

Andersen GO, Oie E, Vinge LE, Yndestad A, Attramadal H, Skomedal T, Osnes JB (2006)
Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts
Basic Res Cardiol, 101 (6), 471-8
PubMed 16783486

Otterdal K, Smith C, Oie E, Pedersen TM, Yndestad A, Stang E, Endresen K, Solum NO, Aukrust P, Damås JK (2006)
Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes
Blood, 108 (3), 928-35
PubMed 16861346

Sandberg WJ, Yndestad A, Øie E, Smith C, Ueland T, Ovchinnikova O, Robertson AK, Müller F, Semb AG, Scholz H, Andreassen AK, Gullestad L, Damås JK, Frøland SS, Hansson GK, Halvorsen B, Aukrust P (2006)
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Arterioscler Thromb Vasc Biol, 26 (4), 857-63
PubMed 16424351

Smith C, Damås JK, Otterdal K, Øie E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Frøland SS, Hansson GK, Aukrust P (2006)
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
J Am Coll Cardiol, 48 (8), 1591-9
PubMed 17045893

Yndestad A, Damås JK, Oie E, Ueland T, Gullestad L, Aukrust P (2006)
Systemic inflammation in heart failure--the whys and wherefores
Heart Fail Rev, 11 (1), 83-92
PubMed 16819581

Yndestad A, Vinge LE, Bjørnerheim R, Ueland T, Wang JE, Frøland SS, Attramadal H, Aukrust P, Oie E (2006)
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats
Eur J Heart Fail, 8 (8), 790-6
PubMed 16549389

Publications 2005

Ahmed MS, von Lueder TG, Øie E, Kjekshus H, Attramadal H (2005)
Induction of myocardial connective tissue growth factor in pacing-induced heart failure in pigs
Acta Physiol Scand, 184 (1), 27-36
PubMed 15847641

Ueland T, Yndestad A, Øie E, Florholmen G, Halvorsen B, Frøland SS, Simonsen S, Christensen G, Gullestad L, Aukrust P (2005)
Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-8
PubMed 15883214

Øie E, Vinge LE, Andersen GØ, Yndestad A, Krobert KA, Sandberg C, Ahmed MS, Haug T, Levy FO, Skomedal T, Attramadal H (2005)
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
PubMed 15623431

Publications 2004

Ahmed MS, Øie E, Vinge LE, Yndestad A, Øystein Andersen G, Andersson Y, Attramadal T, Attramadal H (2004)
Connective tissue growth factor--a novel mediator of angiotensin II-stimulated cardiac fibroblast activation in heart failure in rats
J Mol Cell Cardiol, 36 (3), 393-404
PubMed 15010278

Bucher A, Øie E (2004)
[First choice in empiric treatment of sepsis]
Tidsskr Nor Laegeforen, 124 (24), 3264
PubMed 15645537

von Lueder TG, Kjekshus H, Edvardsen T, ØIe E, Urheim S, Vinge LE, Ahmed MS, Smiseth OA, Attramadal H (2004)
Mechanisms of elevated plasma endothelin-1 in CHF: congestion increases pulmonary synthesis and secretion of endothelin-1
Cardiovasc Res, 63 (1), 41-50
PubMed 15194460

Yndestad A, Ueland T, Øie E, Florholmen G, Halvorsen B, Attramadal H, Simonsen S, Frøland SS, Gullestad L, Christensen G, Damås JK, Aukrust P (2004)
Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
PubMed 14993131

Øie E (2004)
[More about use of antibiotics in sepsis]
Tidsskr Nor Laegeforen, 124 (22), 2942; author reply 2942
PubMed 15550978

Øie E, Bucher A (2004)
[Empiric sepsis treatment in Norway]
Tidsskr Nor Laegeforen, 124 (16), 2154; author reply 2154-5
PubMed 15334146

Publications 2003

Ahmed MS, Øie E, Vinge LE, Yndestad A, Andersen G GØ, Andersson Y, Attramadal T, Attramadal H (2003)
Induction of myocardial biglycan in heart failure in rats--an extracellular matrix component targeted by AT(1) receptor antagonism
Cardiovasc Res, 60 (3), 557-68
PubMed 14659801

Brunvand H, Øie E (2003)
[Apoptosis and cardiovascular disease]
Tidsskr Nor Laegeforen, 123 (7), 930-2
PubMed 12737064

Publications 2002

Oie E, Clausen OP, Yndestad A, Grøgaard HK, Attramadal H (2002)
Endothelin receptor antagonism attenuates cardiomyocyte apoptosis after induction of ischemia in rats
Scand Cardiovasc J, 36 (2), 108-16
PubMed 12028875

Oie E, Yndestad A, Robins SP, Børnerheim R, Asberg A, Attramadal H (2002)
Early intervention with a potent endothelin-A/endothelin-B receptor antagonist aggravates left ventricular remodeling after myocardial infarction in rats
Basic Res Cardiol, 97 (3), 239-47
PubMed 12061394

Publications 2001

Eiken HG, Øie E, Damås JK, Yndestad A, Bjerkeli V, Aass H, Simonsen S, Geiran OR, Tønnessen T, Christensen G, Frøland SS, Gullestad L, Attramadal H, Aukrust P (2001)
Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure
Eur J Clin Invest, 31 (5), 389-97
PubMed 11380590

Hystad ME, Oie E, Grøgaard HK, Kuusnemi K, Vuolteenaho O, Attramadal H, Hall C (2001)
Gene expression of natriuretic peptides and their receptors type-A and -C after myocardial infarction in rats
Scand J Clin Lab Invest, 61 (2), 139-50
PubMed 11347981

Vinge LE, Øie E, Andersson Y, Grøgaard HK, Andersen G, Attramadal H (2001)
Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats
Am J Physiol Heart Circ Physiol, 281 (6), H2490-9
PubMed 11709416

Publications 2000

Damås JK, Eiken HG, Oie E, Bjerkeli V, Yndestad A, Ueland T, Tonnessen T, Geiran OR, Aass H, Simonsen S, Christensen G, Froland SS, Attramadal H, Gullestad L, Aukrust P (2000)
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure
Cardiovasc Res, 47 (4), 778-87
PubMed 10974226

Kjekshus H, Smiseth OA, Klinge R, Oie E, Hystad ME, Attramadal H (2000)
Regulation of ET: pulmonary release of ET contributes to increased plasma ET levels and vasoconstriction in CHF
Am J Physiol Heart Circ Physiol, 278 (4), H1299-310
PubMed 10749728

Oie E, Bjørnerheim R, Clausen OP, Attramadal H (2000)
Cyclosporin A inhibits cardiac hypertrophy and enhances cardiac dysfunction during postinfarction failure in rats
Am J Physiol Heart Circ Physiol, 278 (6), H2115-23
PubMed 10843911

Oie E, Vinge LE, Yndestad A, Sandberg C, Grøgaard HK, Attramadal H (2000)
Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats
Circulation, 101 (4), 415-22
PubMed 10653834

Publications 1998

Hvaal K, Oie E, Attramadal H, Halvorsen V, Svindland A, Nordsletten L, Skjeldal S (1998)
Endothelin-1 is upregulated during skeletal muscle ischemia and reperfusion
J Orthop Res, 16 (1), 128-35
PubMed 9565085

Oie E, Bjønerheim R, Grogaard HK, Kongshaug H, Smiseth OA, Attramadal H (1998)
ET-receptor antagonism, myocardial gene expression, and ventricular remodeling during CHF in rats
Am J Physiol, 275 (3 Pt 2), H868-77
PubMed 9724291

Publications 1997

Oie E, Vinge LE, Tønnessen T, Grøgaard HK, Kjekshus H, Christensen G, Smiseth OA, Attramadal H (1997)
Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
Am J Physiol, 273 (4 Pt 2), H1727-36
PubMed 9362237

Tønnessen T, Christensen G, Oie E, Holt E, Kjekshus H, Smiseth OA, Sejersted OM, Attramadal H (1997)
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats
Cardiovasc Res, 33 (3), 601-10
PubMed 9093530