Andreas Brech

Publications by Andreas Brech

61 publications found

Publications in press

1. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E
   Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
   Int J Cancer (in press)
   PubMed 21866551

Publications 2011

1. Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
   Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
   PLoS One, 6 (7), e21708
   PubMed 21779335
2. Malerød L, Pedersen NM, Sem Wegner CE, Hélène Lobert V, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
   Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
   Traffic, 12 (9), 1211-26
   PubMed 21564451
3. Ugland H, Naderi S, Brech A, Collas P, Blomhoff HK (2011)
   cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
   Autophagy, 7 (10), 1199-211
   PubMed 21750416
4. Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
   Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
   Blood, 118 (12), 3331-9
   PubMed 21725051

Publications 2010

1. Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
   p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
   Autophagy, 6 (3), 330-44
   PubMed 20168092
2. Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
   The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
   Mol Cell, 38 (2), 265-79
   PubMed 20417604
3. Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH (2010)
   Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
   J Infect Dis, 201 (5), 783-92
   PubMed 20121435
4. Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
   Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
   Dev Cell, 19 (1), 148-59
   PubMed 20643357
5. Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
   Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
   J Cell Biol, 190 (4), 523-31
   PubMed 20713604
6. Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
   FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
   J Cell Biol, 188 (2), 253-69
   PubMed 20100911
7. Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
   CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
   EMBO J, 29 (14), 2421-32
   PubMed 20551902
8. Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
   Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
   J Histochem Cytochem, 58 (11), 1025-32
   PubMed 20713985
9. Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2010)
   Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
   Histochem Cell Biol, 133 (1), 41-55
   PubMed 19830447

Publications 2009

1. Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
   Monitoring autophagic degradation of p62/SQSTM1
   Methods Enzymol, 452, 181-97
   PubMed 19200883
2. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
   Autophagy in tumour suppression and promotion
   Mol Oncol, 3 (4), 366-75
   PubMed 19559660
3. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
   Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
   J Cell Sci, 122 (Pt 21), 3883-93
   PubMed 19808888
4. Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
   Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
   Autophagy, 5 (3), 298-302
   PubMed 19066465
5. Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
   SNX4 in complex with clathrin and dynein: implications for endosome movement
   PLoS One, 4 (6), e5935
   PubMed 19529763
6. Stuffers S, Brech A, Stenmark H (2009)
   ESCRT proteins in physiology and disease
   Exp Cell Res, 315 (9), 1619-26
   PubMed 19013455
7. Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
   Multivesicular endosome biogenesis in the absence of ESCRTs
   Traffic, 10 (7), 925-37
   PubMed 19490536
8. Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
   Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
   J Cell Sci, 122 (Pt 14), 2413-23
   PubMed 19571114
9. Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH (2009)
   The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
   J Immunol, 183 (9), 5909-16
   PubMed 19812211

Publications 2008

1. Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
   The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
   Autophagy, 4 (4), 500-6
   PubMed 18326940
2. Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
   Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
   Mol Biol Cell, 19 (10), 4167-76
   PubMed 18685079
3. Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
   Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
   J Cell Biol, 180 (6), 1065-71
   PubMed 18347073
4. Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2008)
   Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
   Autophagy, 4 (2), 176-84
   PubMed 18059160

Publications 2007

1. Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
   Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
   J Cell Biol, 179 (3), 485-500
   PubMed 17984323
2. Malerød L, Stuffers S, Brech A, Stenmark H (2007)
   Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
   Traffic, 8 (11), 1617-29
   PubMed 17714434
3. Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
   p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
   J Biol Chem, 282 (33), 24131-45
   PubMed 17580304
4. Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
   RILP is required for the proper morphology and function of late endosomes
   J Cell Sci, 120 (Pt 21), 3729-37
   PubMed 17959629
5. Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
   ESCRTs and Fab1 regulate distinct steps of autophagy
   Curr Biol, 17 (20), 1817-25
   PubMed 17935992

Publications 2006

1. Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
   The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
   Mol Biol Cell, 17 (6), 2513-23
   PubMed 16554368
2. Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
   Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
   EMBO J, 25 (4), 683-92
   PubMed 16467847
3. Leithe E, Brech A, Rivedal E (2006)
   Endocytic processing of connexin43 gap junctions: a morphological study
   Biochem J, 393 (Pt 1), 59-67
   PubMed 16162097
4. Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
   A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
   Exp Cell Res, 312 (11), 2018-27
   PubMed 16600212
5. Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
   Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
   Mol Biol Cell, 17 (9), 3989-4001
   PubMed 16837550
6. Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
   CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
   EMBO J, 25 (16), 3738-49
   PubMed 16888620

Publications 2005

1. Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
   p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
   J Cell Biol, 171 (4), 603-14
   PubMed 16286508
2. Cabezas A, Bache KG, Brech A, Stenmark H (2005)
   Alix regulates cortical actin and the spatial distribution of endosomes
   J Cell Sci, 118 (Pt 12), 2625-35
   PubMed 15914539
3. Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
   Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
   J Cell Sci, 118 (Pt 17), 3869-81
   PubMed 16091423

Publications 2004

1. Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2004)
   Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
   J Biol Chem, 279 (6), 4794-801
   PubMed 14604990
2. Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
   Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
   Dev Cell, 7 (2), 179-92
   PubMed 15296715
3. Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
   Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
   J Cell Sci, 117 (Pt 18), 4239-51
   PubMed 15292400
4. Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
   Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
   J Cell Sci, 117 (Pt 9), 1807-19
   PubMed 15075241

Publications 2003

1. Bache KG, Brech A, Mehlum A, Stenmark H (2003)
   Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
   J Cell Biol, 162 (3), 435-42
   PubMed 12900395
2. Mousavi SA, Brech A, Berg T, Kjeken R (2003)
   Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
   Biochem J, 372 (Pt 3), 861-9
   PubMed 12646047

Publications 2001

1. Kjeken R, Mousavi SA, Brech A, Gjøen T, Berg T (2001)
   Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells
   Cell Tissue Res, 304 (2), 221-30
   PubMed 11396716
2. Kjeken R, Mousavi SA, Brech A, Griffiths G, Berg T (2001)
   Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
   Biochem J, 357 (Pt 2), 497-503
   PubMed 11439100
3. Mousavi SA, Kjeken R, Berg TO, Seglen PO, Berg T, Brech A (2001)
   Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
   Biochim Biophys Acta, 1510 (1-2), 243-57
   PubMed 11342162

Publications 2000

1. Eliassen TM, Frøystad MK, Dannevig BH, Jankowska M, Brech A, Falk K, Romøren K, Gjøen T (2000)
   Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
   J Virol, 74 (1), 218-27
   PubMed 10590109
2. Løvdal T, Andersen E, Brech A, Berg T (2000)
   Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
   J Cell Sci, 113 ( Pt 18), 3255-66
   PubMed 10954423

Publications 1999

1. Synnes M, Prydz K, Løvdal T, Brech A, Berg T (1999)
   Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
   Biochim Biophys Acta, 1421 (2), 317-28
   PubMed 10518701

Publications 1998

1. Brech A, Kjeken R, Synnes M, Berg T, Roos N, Prydz K (1998)
   Endocytosed ricin and asialoorosomucoid follow different intracellular pathways in hepatocytes
   Biochim Biophys Acta, 1373 (1), 195-208
   PubMed 9733965
2. Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
   EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
   Nature, 394 (6692), 494-8
   PubMed 9697774

Publications 1996

1. Berg T, Gudmundsen O, Brech A, Kjeken R, Gjøen T (1996)
   Clathrin-dependent and clathrin-independent endocytosis in liver cells
   Z Gastroenterol, 34 Suppl 3, 92-4
   PubMed 8767476
2. Brech A, Løvdahl T, Kjeken R, Roos N, Berg T (1996)
   Density shift of endocytic vesicles induced by uptake of colloidal gold particles in rat hepatocytes
   Z Gastroenterol, 34 Suppl 3, 79-80
   PubMed 8767471
3. Tjelle TE, Brech A, Juvet LK, Griffiths G, Berg T (1996)
   Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
   J Cell Sci, 109 ( Pt 12), 2905-14
   PubMed 9013338

Publications 1995

1. Holen I, Gordon PB, Strømhaug PE, Berg TO, Fengsrud M, Brech A, Roos N, Berg T, Seglen PO (1995)
   Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
   Biochem J, 311 ( Pt 1), 317-26
   PubMed 7575471
2. Kjeken R, Brech A, Løvdal T, Roos N, Berg T (1995)
   Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
   Exp Cell Res, 216 (2), 290-8
   PubMed 7843273

Publications 1993

1. Brech A, Magnusson S, Stang E, Berg T, Roos N (1993)
   Receptor-mediated endocytosis of ricin in rat liver endothelial cells. An immunocytochemical study
   Eur J Cell Biol, 60 (1), 154-62
   PubMed 8462592