Ioannis P. Nezis
Position: Postdoc (ERC)
Phone: +47 22 78 19 21
Email:

From the news:

Mediating protein aggregation in the brain.

 

Mechanistic link between autophagy and programmed cell death identified

 

Author network for Ioannis P. Nezis by COREMINE medical


Publications in press

Nezis IP, Stenmark H
p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer
Antioxid Redox Signal (in press)
PubMed 22074114

Publications 2012

Nezis IP (2012)
Selective autophagy in Drosophila
Int J Cell Biol, 2012, 146767
PubMed 22567011

Publications 2011

Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
Autophagy, 7 (6), 572-83
PubMed 21325881

Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
PubMed 21509167

Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
PubMed 21455500

Publications 2010

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
PubMed 20451383

Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin EC, Tettamanti G, Umemiya-Shirafuji R (2010)
Autophagy and its physiological relevance in arthropods: Current knowledge and perspectives
Autophagy, 6 (5), 575-588
PubMed 20458176

Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
PubMed 20880709

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
PubMed 20935512

Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
PubMed 20713604

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530

Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
PubMed 20551902

Publications 2009

Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
PubMed 19066465

Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
PubMed 19571114

Publications 2008

Mpakou VE, Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2008)
Different modes of programmed cell death during oogenesis of the silkmoth Bombyx mori
Autophagy, 4 (1), 97-100
PubMed 17986869

Nezis IP, Papassideri I (2008)
Monitoring autophagy in insect eggs
Methods Enzymol, 451, 669-83
PubMed 19185745

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
PubMed 18347073

Publications 2007

Hatziantoniou S, Nezis IP, Margaritis LH, Demetzos C (2007)
Visualisation of liposomes prepared from skin and stratum corneum lipids by transmission electron microscopy
Micron, 38 (8), 777-81
PubMed 17681473

Panagopoulos DJ, Chavdoula ED, Nezis IP, Margaritis LH (2007)
Cell death induced by GSM 900-MHz and DCS 1800-MHz mobile telephony radiation
Mutat Res, 626 (1-2), 69-78
PubMed 17045516

Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
PubMed 17935992

Velentzas AD, Nezis IP, Stravopodis DJ, Papassideri IS, Margaritis LH (2007)
Apoptosis and autophagy function cooperatively for the efficacious execution of programmed nurse cell death during Drosophila virilis oogenesis
Autophagy, 3 (2), 130-2
PubMed 17183224

Velentzas AD, Nezis IP, Stravopodis DJ, Papassideri IS, Margaritis LH (2007)
Stage-specific regulation of programmed cell death during oogenesis of the medfly Ceratitis capitata (Diptera, Tephritidae)
Int J Dev Biol, 51 (1), 57-66
PubMed 17183465

Velentzas AD, Nezis IP, Stravopodis DJ, Papassideri IS, Margaritis LH (2007)
Mechanisms of programmed cell death during oogenesis in Drosophila virilis
Cell Tissue Res, 327 (2), 399-414
PubMed 17004067

Publications 2006

Mpakou VE, Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2006)
Programmed cell death of the ovarian nurse cells during oogenesis of the silkmoth Bombyx mori
Dev Growth Differ, 48 (7), 419-28
PubMed 16961589

Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2006)
Autophagy is required for the degeneration of the ovarian follicular epithelium in higher Diptera
Autophagy, 2 (4), 297-8
PubMed 16921270

Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2006)
Follicular atresia during Dacus oleae oogenesis
J Insect Physiol, 52 (3), 282-90
PubMed 16368106

Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2006)
Programmed cell death of follicular epithelium during the late developmental stages of oogenesis in the fruit flies Bactrocera oleae and Ceratitis capitata (Diptera, Tephritidae) is mediated by autophagy
Dev Growth Differ, 48 (3), 189-98
PubMed 16573736

Nezis IP, Stravopodis DJ, Margaritis LH, Papassideri IS (2006)
Chromatin condensation of ovarian nurse and follicle cells is regulated independently from DNA fragmentation during Drosophila late oogenesis
Differentiation, 74 (6), 293-304
PubMed 16831198

Publications 2005

Chondrogianni N, Tzavelas C, Pemberton AJ, Nezis IP, Rivett AJ, Gonos ES (2005)
Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates
J Biol Chem, 280 (12), 11840-50
PubMed 15661736

Nezis IP, Stravopodis DJ, Papassideri IS, Stergiopoulos C, Margaritis LH (2005)
Morphological irregularities and features of resistance to apoptosis in the dcp-1/pita double mutated egg chambers during Drosophila oogenesis
Cell Motil Cytoskeleton, 60 (1), 14-23
PubMed 15547953

Publications 2003

Nezis IP, Modes V, Mpakou V, Stravopodis DJ, Papassideri IS, Mammali I, Margaritis LH (2003)
Modes of programmed cell death during Ceratitis capitata oogenesis
Tissue Cell, 35 (2), 113-9
PubMed 12747933

Publications 2002

Nezis IP, Stravopodis DJ, Papassideri I, Robert-Nicoud M, Margaritis LH (2002)
Dynamics of apoptosis in the ovarian follicle cells during the late stages of Drosophila oogenesis
Cell Tissue Res, 307 (3), 401-9
PubMed 11904777

Publications 2001

Nezis IP, Stravopodis DJ, Papassideri I, Margaritis LH (2001)
Actin cytoskeleton reorganization of the apoptotic nurse cells during the late developmental stages of oogenesis in Dacus oleae
Cell Motil Cytoskeleton, 48 (3), 224-33
PubMed 11223953

Publications 2000

Nezis IP, Stravopodis DJ, Papassideri I, Robert-Nicoud M, Margaritis LH (2000)
Stage-specific apoptotic patterns during Drosophila oogenesis
Eur J Cell Biol, 79 (9), 610-20
PubMed 11043402

Publications 1999

Xanthou G, Tapinos NI, Polihronis M, Nezis IP, Margaritis LH, Moutsopoulos HM (1999)
CD4 cytotoxic and dendritic cells in the immunopathologic lesion of Sjögren's syndrome
Clin Exp Immunol, 118 (1), 154-63
PubMed 10540173