Author network for Harald Stenmark by COREMINE medical

Publications in press

Nezis IP, Stenmark H
p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer
Antioxid Redox Signal (in press)
PubMed 22074114

Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2) (in press)
PubMed 18204305

Publications 2012

Lobert VH, Stenmark H (2012)
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
PubMed 22266905

Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
PubMed 21936852

Rusten TE, Vaccari T, Stenmark H (2012)
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
PubMed 22193162

Publications 2011

Abrahamsen H, Stenmark H (2011)
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
PubMed 22053037

Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
PubMed 21509167

Hurley JH, Stenmark H (2011)
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
PubMed 21332354

Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
PubMed 21499309

Lobert VH, Stenmark H (2011)
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
PubMed 21670163

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
PubMed 21564451

Platta HW, Stenmark H (2011)
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
PubMed 21474295

Raiborg C, Stenmark H (2011)
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
PubMed 21436431

Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
PubMed 21455500

Schink KO, Stenmark H (2011)
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
PubMed 22153165

Stenmark H (2011)
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
PubMed 21339328

Wegner CS, Rodahl LM, Stenmark H (2011)
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
PubMed 21518165

Publications 2010

Abrahamsen H, Stenmark H (2010)
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
PubMed 20462486

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
PubMed 20168092

Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
PubMed 20417604

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
PubMed 20451383

Hansson EM, Lanner F, Das D, Mutvei A, Marklund U, Ericson J, Farnebo F, Stumm G, Stenmark H, Andersson ER, Lendahl U (2010)
Control of Notch-ligand endocytosis by ligand-receptor interaction
J Cell Sci, 123 (Pt 17), 2931-42
PubMed 20720151

Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
PubMed 20933442

Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
PubMed 20724836

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
PubMed 20643357

Lobert VH, Stenmark H (2010)
Ubiquitination of ?-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
PubMed 21331246

Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
PubMed 20880709

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
PubMed 20935512

Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
PubMed 20713604

Roxrud I, Stenmark H, Malerød L (2010)
ESCRT & Co
Biol Cell, 102 (5), 293-318
PubMed 20222872

Rusten TE, Stenmark H (2010)
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
PubMed 20190829

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
PubMed 20371245

Stenmark H (2010)
The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
FEBS J, 277 (23), 4837-48
PubMed 20977678

Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
PubMed 20713985

Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
PubMed 20643123

Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2010)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
PubMed 19830447

Publications 2009

Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
PubMed 19559660

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888

Malerød L, Stenmark H (2009)
ESCRTing membrane deformation
Cell, 136 (1), 15-7
PubMed 19135881

Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
PubMed 19066465

Raiborg C, Stenmark H (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
PubMed 19325624

Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
PubMed 19194501

Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
PubMed 19143618

Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
PubMed 19619532

Rusten TE, Stenmark H (2009)
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
PubMed 19535733

Stenmark H (2009)
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
PubMed 19702012

Stenmark H (2009)
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
PubMed 19603039

Stuffers S, Brech A, Stenmark H (2009)
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
PubMed 19013455

Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
PubMed 19490536

Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
PubMed 19571114

Publications 2008

Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
PubMed 18188183

Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
PubMed 18342287

Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y et al. (2008)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
PubMed 18188003

Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
PubMed 18326940

Miaczynska M, Stenmark H (2008)
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
PubMed 18195098

Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
PubMed 18685079

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
PubMed 18347073

Raiborg C, Malerød L, Pedersen NM, Stenmark H (2008)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
PubMed 18031739

Raposo G, Stenmark H (2008)
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
PubMed 18588977

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H (2008)
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
PubMed 18362181

Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236

Simonsen A, Stenmark H (2008)
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
PubMed 18725534

Umebayashi K, Stenmark H, Yoshimori T (2008)
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
PubMed 18508924

Publications 2007

Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
PubMed 17335953

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
PubMed 17984323

Haglund K, Rusten TE, Stenmark H (2007)
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
PubMed 17956217

Malerød L, Stenmark H (2007)
ESCRTs
Curr Biol, 17 (2), R42-3
PubMed 17240322

Malerød L, Stuffers S, Brech A, Stenmark H (2007)
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
PubMed 17714434

Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
PubMed 17959629

Rusten TE, Stenmark H (2007)
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
PubMed 17268460

Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
PubMed 17935992

Simonsen A, Stenmark H (2007)
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
PubMed 17510644

Publications 2006

Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
PubMed 16554368

Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
PubMed 16448788

Haglund K, Stenmark H (2006)
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
PubMed 17077855

Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
PubMed 16462748

Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
PubMed 17057714

Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
PubMed 16429130

Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
PubMed 16467847

Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
PubMed 16600212

Lindmo K, Stenmark H (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
PubMed 16467569

Lindmo K, Stenmark H (2006)
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
PubMed 16874068

Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
PubMed 16859684

Raiborg C, Slagsvold T, Stenmark H (2006)
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
PubMed 16901703

Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
PubMed 16720641

Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
PubMed 16837550

Rusten TE, Stenmark H (2006)
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
PubMed 16554828

Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
PubMed 16954148

Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
PubMed 16888620

Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
PubMed 16716591

Publications 2005

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
PubMed 16286508

Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
PubMed 15914539

Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
PubMed 15882625

Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
PubMed 15634330

Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
PubMed 15755741

Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
PubMed 16032929

Publications 2004

Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
PubMed 15240819

Bache KG, Slagsvold T, Stenmark H (2004)
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
PubMed 15229652

Birkeland HC, Stenmark H (2004)
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
PubMed 14594215

Gruenberg J, Stenmark H (2004)
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
PubMed 15071556

Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2004)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
PubMed 14604990

Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
PubMed 15296715

Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
PubMed 15007060

Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
PubMed 15292400

Slagsvold T, Stenmark H (2004)
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
PubMed 15469831

Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
PubMed 15194809

Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
PubMed 15121875

Publications 2003

Bache KG, Brech A, Mehlum A, Stenmark H (2003)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
PubMed 12900395

Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
PubMed 12551915

Gillooly DJ, Raiborg C, Stenmark H (2003)
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
PubMed 14618335

González-Gaitán M, Stenmark H (2003)
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
PubMed 14651844

Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
PubMed 14602072

Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
PubMed 12975344

Raiborg C, Rusten TE, Stenmark H (2003)
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
PubMed 12892785

Publications 2002

Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
PubMed 12180964

Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
PubMed 11870209

Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
PubMed 12010460

Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
PubMed 11877415

Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
PubMed 11988743

Raiborg C, Stenmark H (2002)
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
PubMed 12576633

Stenmark H, Aasland R, Driscoll PC (2002)
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
PubMed 11911884

Publications 2001

Gillooly DJ, Simonsen A, Stenmark H (2001)
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
PubMed 11284710

Gillooly DJ, Simonsen A, Stenmark H (2001)
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
PubMed 11581282

Gillooly DJ, Stenmark H (2001)
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
PubMed 11232585

Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
PubMed 11226186

Pattni K, Jepson M, Stenmark H, Banting G (2001)
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
PubMed 11676927

Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
PubMed 11532964

Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
PubMed 11498011

Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
PubMed 11493665

Simonsen A, Stenmark H (2001)
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
PubMed 11483972

Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
PubMed 11454456

Stenmark H (2001)
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
PubMed 11292379

Stenmark H, Gillooly DJ (2001)
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
PubMed 11292385

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
PubMed 11387043

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol., 2 (5), 3007.1

Publications 2000

Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
PubMed 10984443

Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
PubMed 10807926

Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
PubMed 10970851

Stenmark H (2000)
Cycling lipids
Curr Biol, 10 (2), R57-9
PubMed 10662657

Stenmark H (2000)
Membrane traffic: Cycling lipids
Curr. Biol., 10 (2), R57-R59

Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
PubMed 11003664

Publications 1999

Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999)
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
PubMed 10491193

Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2), 539-43
PubMed 10024533

Corvera S, D'Arrigo A, Stenmark H (1999)
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
PubMed 10449332

Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
PubMed 10917663

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
PubMed 10358931

Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
PubMed 10506127

Stenmark H, Aasland R (1999)
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
PubMed 10564636

Publications 1998

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
PubMed 9697764

Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1998)
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
PubMed 9524116

Kolpakova E, Wied?ocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
PubMed 9806903

Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
PubMed 9587053

Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
PubMed 9697774

Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1998)
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
PubMed 9524117

Waite RL, Sentry JW, Stenmark H, Toh BH (1998)
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
PubMed 9434799

Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1998)
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
PubMed 9490718

Publications 1997

D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016

Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
PubMed 9323142

Olkkonen VM, Stenmark H (1997)
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
PubMed 9394917

Publications 1996

Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
PubMed 8798641

Publications 1995

Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine >fingers> and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
PubMed 7768953

Singer-Krüger B, Stenmark H, Zerial M (1995)
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
PubMed 8586662

Stenmark H, Bucci C, Zerial M (1995)
Expression of Rab GTPases using recombinant vaccinia viruses
Methods Enzymol, 257, 155-64
PubMed 8583918

Stenmark H, Vitale G, Ullrich O, Zerial M (1995)
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
PubMed 8521472

Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
PubMed 8824393

Publications 1994

de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
PubMed 8043272

Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
PubMed 8163546

Stenmark H, Parton RG, Steele-Mortimer O, Lütcke A, Gruenberg J, Zerial M (1994)
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
EMBO J, 13 (6), 1287-96
PubMed 8137813

Stenmark H, Valencia A, Martinez O, Ullrich O, Goud B, Zerial M (1994)
Distinct structural elements of rab5 define its functional specificity
EMBO J, 13 (3), 575-83
PubMed 8313902

Publications 1993

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
PubMed 8418864

Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690

Zerial M, Stenmark H (1993)
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
PubMed 8257602

Publications 1992

Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
PubMed 1639497

Madshus IH, Stenmark H (1992)
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
PubMed 1378368

Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3), 619-25
PubMed 1536643

Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382

Publications 1991

Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632

Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012

Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
PubMed 2040642

Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
PubMed 1646374

Publications 1990

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980

Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
PubMed 1696341

Publications 1989

McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
PubMed 2684631

Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882

OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751

Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
PubMed 2479538

Publications 1988

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
PubMed 3072713

Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666