Harald Stenmark
Position: Group leader, Professor (CCB)
Phone: +47 22 78 18 18
Email:

CV

Education: Cand.Pharm. 1985 at the University of Oslo

Doctoral degree: Dr.Philos. (Ph.D.) 1991 at the Norwegian Radium Hospital

Postdoctoral training: From August 1991 to November 1994 in Marino Zerial's group at EMBL, Heidelberg

Independent investigator award: From December 1994 to December 1996, the Norwegian Cancer Society

Group leader position: From 1997 to present, group leader at the Norwegian Radium Hospital

Adjunct professorships: From 1999 to 2003, professor II at the Institute of Pharmacy, Oslo. From 2004 to present, professor II at the Institute for Cancer Research and Molecular Medicine, Trondheim.

Current positions: From September 2007, Director, Centre for Cancer Biomedicine, and Professor, the Medical Faculty of the University of Oslo. From November 2009, Head of Department of Biochemistry, the Norwegian Radium Hospital.


Awards and honours:

1998 Investigator of the Top Research Programme

1999 Anders Jahre’s prize for Nordic medical scientists under 40 years

2000 Olav Torgersen’s prize

2002 Research Prize of the Norwegian Radium Hospital

2002 Elected member of EMBO

2004 Elected member of the Norwegian Academy of Science

2007 Centre of Excellence grant from the Research Council of Norway

2009 Advanced Grant from the European Research Council

2010 Sir Hans Krebs Medal

2011 Elected member of the European Academy of Cancer Sciences

2013 Research Prize of Oslo University Hospital

2014 H.M. King Olav V's prize for Cancer Research


Editorial boards:

Autophagy

Biochemical Journal

Current Biology

Developmental Cell

Experimental Cell Research

Journal of Cell Biology

Traffic

EMBO Journal


Selected publications

Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C and Stenmark H (2014). ANCHR mediates Aurora B-dependent abscission checkpoint control through retention of VPS4. Nat. Cell Biol. 16: 550-560

Rusten TE, Vaccari T and Stenmark H (2012). Shaping development with ESCRTs. Nat.Cell Biol. 14: 38-45

Schink KO and Stenmark H (2012). Midbody remnants – junk or fate factors? Curr.Biol. 21: R958-R960

Abrahamsen H and Stenmark H (2011). Growth signaling from inside. Science 334: 611-612

Raiborg C and Stenmark H (2011). A helix for the final cut. Science 331: 1533-1534

Nezis IP, Shravage BP, Lamark T, Rusten TE, Sagona AP, Bjørkøy G, Johansen T, Brech A, Baehrecke E and Stenmark H (2010). Autophagic degradation of inhibitor of apoptosis dBruce triggers cell death during late oogenesis in Drosophila. J. Cell Biol. 190: 523-531

Abrahamsen H and Stenmark H (2010). Unconventional exit by exophagy. Curr.Biol. 20: R415-R418

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R and Stenmark H (2010). Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster. Curr.Biol. 20: 944-950

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L and Stenmark H (2010). Ubiquitination of α5β1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes. Dev. Cell 19: 148-159

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C and Stenmark H (2010). PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nat. Cell Biol. 12: 362-371

Rusten TE and Stenmark H (2010). p62, an autophagy hero or culprit? Nat. Cell Biol. 12: 207-209

Raiborg C and Stenmark H (2009). The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature 458: 445-453

Malerød L and Stenmark H (2009). ESCRTing membrane deformation. Cell 136: 15-17

Roxrud I, Raiborg C, Pedersen NM, Stang E and Stenmark H (2008). An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor. J. Cell Biol. 180: 1205-1218

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H and Brech A (2008). Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain. J. Cell Biol. 180: 1065-1071

Simonsen A and Stenmark H (2007). Stimulating the cell's appetite for itself. Nat. Chem.Biol. 3: 304-306

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Isaacs A, Fisher E, Brech A, Stenmark H and Simonsen A (2007). Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J. Cell Biol. 179: 485-500

Rusten TE, Vaccari T, Lindmo K, Rodahl LMW, Nezis, IP, Sem-Jacobsen C, Wendler F, Vincent J-P, Brech A, Bilder D and Stenmark H (2007). ESCRTs and Fab1 regulate distinct steps of autophagy. Curr. Biol. 17: 1817-1825

Rusten TE and Stenmark H (2007). Moonlighting at the pole. Nature 445: 497-499

Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H and Wakatsuki S (2006). Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain. Nat. Struct. Mol. Biol. 13: 1031-1032

Haglund K and Stenmark H (2006). Working out coupled monoubiquitination. Nat. Cell Biol. 8; 1218-1219

Slagsvold T, Marchese A, Brech A and Stenmark H (2006). CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4. EMBO J. 25: 3738-3749

Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H and Wakatsuki S (2006). Double sided ubiquitin binding of Hrs-UIM in endosomal protein sorting. Nat.Struct.Mol.Biol. 13: 272-277.

Hoeller D, Crosetto N, Blagoev B, Raiborg C, Wagner S, Kowanetz K, Tikkanen R, Breitling R, Mann M, Stenmark H and Dikic I (2006). Regulation of ubiquitin-binding proteins by monoubiquitylation. Nat.Cell Biol. 8: 163-169

Rusten TE and Stenmark H (2006). Analyzing phosphoinositides and their interacting proteins. Nat. Methods 3: 251-258

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Øvervatn A, Stenmark H and Johansen T (2005). p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171: 603-614

Hoepfner S, Severin F, Cabezas A, Habermann A, Runge A, Gillooly DJ, Stenmark H and Zerial M (2005). Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell 121: 437-450

Slagsvold T and Stenmark H (2004). The structure of an endosomal protein sorter. Dev. Cell 7: 457-458

Rusten TE, Lindmo K, Juhasz G, Sass M, Seglen P, Brech A and Stenmark H (2004). Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev.Cell 7: 179-192.

Bache KG, Slagsvold T and Stenmark H (2004). Defective downregulation of receptor tyrosine kinases in cancer. EMBO J. 23: 2707-2712

Sharma M, Pampinella F, Nemes C, Benharouga M, Papsin B, So J, Du K, Bache KG, Papsin B, Zherangue N, Stenmark H and Lukacs GL (2004). Misfolding diverts cell surface CFTR from recycling to degradation: protein quality control at sorting endosomes. J.Cell Biol. 164: 923-933

Gruenberg J and Stenmark H (2004). The biogenesis of multivesicular endosomes. Nat.Rev.Mol.Cell Biol.: 5: 317-323

Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H and Benovic JL (2003). The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. Dev. Cell 5: 709-722

Bache KG, Brech A, Mehlum A and Stenmark H (2003). Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J.Cell Biol. 162: 435-442.

Petiot A, Fauré J, Stenmark H and Gruenberg J (2003). PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J.Cell Biol. 162: 971-979

González-Gaitán M and Stenmark H (2003). Endocytosis and signaling: a relationship under development. Cell 115: 513-521

Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E and Stenmark H (2002) Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat. Cell Biol. 4: 394-398.

Gillooly D, Simonsen A and Stenmark H (2001). Phosphoinositides and phagocytosis. J. Cell Biol. 155: 15-17

Pattni K, Jepson M, Stenmark H and Banting G (2001). A PI(3)P specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells. Curr.Biol. 11: 1636-1642

Raiborg C, Bache KG, Mehlum A, Stang E and Stenmark H (2001) Hrs recruits clathrin to early endosomes. EMBO J. 20: 5008-5021.

Simonsen A and Stenmark H (2001) PX domains: attracted by phosphoinositides. Nat. Cell Biol. 3: E179-E182

Gillooly DJ and Stenmark H (2001) A lipid oils the endocytosis machine. Science 291: 993-994

Gillooly DJ, Morrow, IC, Lindsay M, Gould R, Bryant, NJ, Gaullier J-M, Parton RG and Stenmark H (2000) Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 19: 4577-4588.

Stenmark H (2000) Cycling lipids. Curr. Biol. 10: R57-R59

Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M and Murphy C (1998) Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. J. Cell Biol. 140: 1039-1053

Gournier H, Stenmark H, Rybin V, Lippé R and Zerial M (1998) Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion. EMBO J. 17: 1930-1940

Vitale G, Rybin V, Christoforidis S, Thornquist P-O, McCaffrey M, Stenmark H and Zerial M (1998) Two distinct Rab binding domains mediate the direct interaction between Rabaptin-5 and GTP-bound Rab4 and Rab5. EMBO J. 17: 1941-1951

Simonsen A, Lippé R, Christoforidis S, Gaullier J-M, Brech A, Callaghan JM, Toh B-H, Murphy C, Zerial M and Stenmark H (1998) EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature 394: 494-498.

Gaullier J-M, Simonsen A, D’Arrigo A, Bremnes B, Aasland R and Stenmark H (1998) FYVE fingers bind PtdIns(3)P. Nature 394: 432-433.

Stenmark H, Vitale G, Ullrich O and Zerial M (1995) Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. Cell 83: 423-432

Stenmark H, Valencia A, Martinez O, Ullrich O, Goud B and Zerial M (1994) Distinct structural elements of rab5 define its functional specificity. EMBO J. 13: 575-583.

Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo J-S, Gallwitz D and Zerial M (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J. Cell Biol. 125: 283-298

Stenmark H, Parton RG, Steele-Mortimer O, Lütcke A, Gruenberg J and Zerial M (1994) Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J. 13: 1287-1296

Stenmark H, Moskaug JØ, Madshus IH, Sandvig K and Olsnes S (1991) Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol. J. Cell Biol. 113: 1025-1032

McGill S, Stenmark H, Sandvig K and Olsnes S (1989) Membrane interactions of diphtheria toxin analyzed using in vitro translated mutants. EMBO J. 8: 2843-2848

Stenmark H, McGill S, Olsnes S and Sandvig K (1989) Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin. EMBO J. 8: 2849-2853

 
 
 
 
 
 

Author network for Harald Stenmark by COREMINE medical


Publications 2014

Oeste CL, Pinar M, Schink KO, Martínez-Turrión J, Stenmark H, Peñalva MA, Pérez-Sala D (2014)
An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species
PLoS One, 9 (9), e107190
PubMed 25207810

Sagona AP, Nezis IP, Stenmark H (2014)
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
PubMed 24741567

Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
PubMed 24440309

Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
PubMed 24814515

Publications 2013

Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-26
PubMed 23567040

Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
PubMed 23499247

Henne WM, Stenmark H, Emr SD (2013)
Molecular mechanisms of the membrane sculpting ESCRT pathway
Cold Spring Harb Perspect Biol, 5 (9)
PubMed 24003212

Hämälistö S, Pouwels J, de Franceschi N, Saari M, Ivarsson Y, Zimmermann P, Brech A, Stenmark H, Ivaska J (2013)
A ZO-1/?5?1-integrin complex regulates cytokinesis downstream of PKC? in NCI-H460 cells plated on fibronectin
PLoS One, 8 (8), e70696
PubMed 23967087

Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Autophagy, 9 (12), 1955-64
PubMed 24128730

Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
PubMed 23878278

Kostaras E, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2013)
SARA and RNF11 at the crossroads of EGFR signaling and trafficking
Methods Enzymol, 535, 225-47
PubMed 24377927

O Farrell F, Rusten TE, Stenmark H (2013)
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
FEBS J, 280 (24), 6322-37
PubMed 23953235

Raiborg C, Schink KO, Stenmark H (2013)
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J, 280 (12), 2730-42
PubMed 23289851

Schink KO, Raiborg C, Stenmark H (2013)
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
PubMed 23881848

Wegner CS, Schink KO, Stenmark H, Brech A (2013)
Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
Methods Enzymol, 534, 3-23
PubMed 24359945

Publications 2012

Abrahamsen H, Stenmark H, Platta HW (2012)
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
FEBS Lett, 586 (11), 1584-91
PubMed 22673570

Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2012)
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking
Oncogene, 32 (44), 5220-32
PubMed 23222715

Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene ?-catenin
EMBO Rep, 14 (1), 10-1
PubMed 23229585

Lobert VH, Stenmark H (2012)
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
PubMed 22266905

Nezis IP, Stenmark H (2012)
p62 at the interface of autophagy, oxidative stress signaling, and cancer
Antioxid Redox Signal, 17 (5), 786-93
PubMed 22074114

Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
PubMed 23154468

Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
PubMed 22816767

Stenmark H (2012)
The Rabs: a family at the root of metazoan evolution
BMC Biol, 10, 68
PubMed 22873178

Publications 2011

Abrahamsen H, Stenmark H (2011)
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
PubMed 22053037

Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
PubMed 21509167

Hurley JH, Stenmark H (2011)
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
PubMed 21332354

Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
PubMed 21499309

Lobert VH, Stenmark H (2011)
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
PubMed 21670163

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
PubMed 21564451

Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2011)
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
PubMed 21936852

Platta HW, Stenmark H (2011)
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
PubMed 21474295

Raiborg C, Stenmark H (2011)
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
PubMed 21436431

Rusten TE, Vaccari T, Stenmark H (2011)
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
PubMed 22193162

Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
PubMed 21455500

Schink KO, Stenmark H (2011)
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
PubMed 22153165

Stenmark H (2011)
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
PubMed 21339328

Wegner CS, Rodahl LM, Stenmark H (2011)
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
PubMed 21518165

Publications 2010

Abrahamsen H, Stenmark H (2010)
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
PubMed 20462486

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
PubMed 20168092

Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
PubMed 20417604

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
PubMed 20451383

Hansson EM, Lanner F, Das D, Mutvei A, Marklund U, Ericson J, Farnebo F, Stumm G, Stenmark H, Andersson ER, Lendahl U (2010)
Control of Notch-ligand endocytosis by ligand-receptor interaction
J Cell Sci, 123 (Pt 17), 2931-42
PubMed 20720151

Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
PubMed 20933442

Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2010)
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
PubMed 22966490

Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
PubMed 20724836

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
PubMed 20643357

Lobert VH, Stenmark H (2010)
Ubiquitination of ?-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
PubMed 21331246

Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
PubMed 20880709

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
PubMed 20935512

Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
PubMed 20713604

Roxrud I, Stenmark H, Malerød L (2010)
ESCRT & Co
Biol Cell, 102 (5), 293-318
PubMed 20222872

Rusten TE, Stenmark H (2010)
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
PubMed 20190829

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
PubMed 20371245

Stenmark H (2010)
The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
FEBS J, 277 (23), 4837-48
PubMed 20977678

Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
PubMed 20713985

Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
PubMed 20643123

Publications 2009

Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
PubMed 19559660

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888

Malerød L, Stenmark H (2009)
ESCRTing membrane deformation
Cell, 136 (1), 15-7
PubMed 19135881

Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
PubMed 19066465

Raiborg C, Stenmark H (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
PubMed 19325624

Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
PubMed 19194501

Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
PubMed 19143618

Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
PubMed 19619532

Rusten TE, Stenmark H (2009)
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
PubMed 19535733

Stenmark H (2009)
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
PubMed 19702012

Stenmark H (2009)
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
PubMed 19603039

Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
PubMed 19490536

Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
PubMed 19571114

Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
PubMed 19830447

Publications 2008

Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
PubMed 18188183

Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
PubMed 18342287

Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
PubMed 18326940

Miaczynska M, Stenmark H (2008)
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
PubMed 18195098

Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
PubMed 18685079

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
PubMed 18347073

Raposo G, Stenmark H (2008)
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
PubMed 18588977

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H (2008)
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
PubMed 18362181

Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236

Simonsen A, Stenmark H (2008)
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
PubMed 18725534

Stuffers S, Brech A, Stenmark H (2008)
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
PubMed 19013455

Umebayashi K, Stenmark H, Yoshimori T (2008)
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
PubMed 18508924

Publications 2007

Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
PubMed 17335953

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
PubMed 17984323

Haglund K, Rusten TE, Stenmark H (2007)
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
PubMed 17956217

Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y et al. (2007)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
PubMed 18188003

Malerød L, Stenmark H (2007)
ESCRTs
Curr Biol, 17 (2), R42-3
PubMed 17240322

Malerød L, Stuffers S, Brech A, Stenmark H (2007)
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
PubMed 17714434

Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
PubMed 17959629

Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
PubMed 18031739

Rusten TE, Stenmark H (2007)
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
PubMed 17268460

Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
PubMed 17935992

Simonsen A, Stenmark H (2007)
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
PubMed 17510644

Publications 2006

Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
PubMed 16554368

Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
PubMed 16448788

Haglund K, Stenmark H (2006)
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
PubMed 17077855

Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
PubMed 16462748

Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
PubMed 17057714

Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
PubMed 16429130

Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
PubMed 16467847

Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
PubMed 16600212

Lindmo K, Stenmark H (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
PubMed 16467569

Lindmo K, Stenmark H (2006)
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
PubMed 16874068

Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
PubMed 16859684

Raiborg C, Slagsvold T, Stenmark H (2006)
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
PubMed 16901703

Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
PubMed 16720641

Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
PubMed 16837550

Rusten TE, Stenmark H (2006)
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
PubMed 16554828

Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
PubMed 16954148

Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
PubMed 16888620

Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
PubMed 16716591

Publications 2005

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
PubMed 16286508

Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
PubMed 15914539

Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
PubMed 15882625

Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
PubMed 15634330

Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
PubMed 15755741

Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
PubMed 16032929

Publications 2004

Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
PubMed 15240819

Bache KG, Slagsvold T, Stenmark H (2004)
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
PubMed 15229652

Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
PubMed 15296715

Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
PubMed 15007060

Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
PubMed 15292400

Slagsvold T, Stenmark H (2004)
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
PubMed 15469831

Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
PubMed 15194809

Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
PubMed 15121875

Publications 2003

Bache KG, Brech A, Mehlum A, Stenmark H (2003)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
PubMed 12900395

Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
PubMed 12551915

Birkeland HC, Stenmark H (2003)
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
PubMed 14594215

Gillooly DJ, Raiborg C, Stenmark H (2003)
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
PubMed 14618335

González-Gaitán M, Stenmark H (2003)
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
PubMed 14651844

Gruenberg J, Stenmark H (2003)
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
PubMed 15071556

Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
PubMed 14602072

Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
PubMed 14604990

Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
PubMed 12975344

Raiborg C, Rusten TE, Stenmark H (2003)
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
PubMed 12892785

Publications 2002

Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
PubMed 12180964

Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
PubMed 11870209

Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
PubMed 12010460

Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
PubMed 11877415

Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
PubMed 11988743

Raiborg C, Stenmark H (2002)
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
PubMed 12576633

Stenmark H, Aasland R, Driscoll PC (2002)
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
PubMed 11911884

Publications 2001

Gillooly DJ, Simonsen A, Stenmark H (2001)
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
PubMed 11284710

Gillooly DJ, Simonsen A, Stenmark H (2001)
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
PubMed 11581282

Gillooly DJ, Stenmark H (2001)
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
PubMed 11232585

Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
PubMed 11226186

Pattni K, Jepson M, Stenmark H, Banting G (2001)
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
PubMed 11676927

Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
PubMed 11532964

Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
PubMed 11498011

Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
PubMed 11493665

Simonsen A, Stenmark H (2001)
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
PubMed 11483972

Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
PubMed 11454456

Stenmark H (2001)
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
PubMed 11292379

Stenmark H, Gillooly DJ (2001)
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
PubMed 11292385

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol., 2 (5), 3007.1

Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
PubMed 11387043

Publications 2000

Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
PubMed 10984443

Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
PubMed 10807926

Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
PubMed 10970851

Stenmark H (2000)
Membrane traffic: Cycling lipids
Curr. Biol., 10 (2), R57-R59

Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
PubMed 11003664

Publications 1999

Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
PubMed 10917663

Publications 1998

Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1998)
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
PubMed 10491193

Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1998)
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2), 539-43
PubMed 10024533

Corvera S, D'Arrigo A, Stenmark H (1998)
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
PubMed 10449332

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1998)
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
PubMed 10358931

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
PubMed 9697764

Kolpakova E, Wied?ocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
PubMed 9806903

Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
PubMed 9587053

Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1998)
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
PubMed 10506127

Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
PubMed 9697774

Stenmark H (1998)
Cycling lipids
Curr Biol, 10 (2), R57-9
PubMed 10662657

Stenmark H, Aasland R (1998)
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
PubMed 10564636

Publications 1997

D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016

Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1997)
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
PubMed 9524116

Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
PubMed 9323142

Olkkonen VM, Stenmark H (1997)
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
PubMed 9394917

Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1997)
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
PubMed 9524117

Waite RL, Sentry JW, Stenmark H, Toh BH (1997)
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
PubMed 9434799

Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1997)
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
PubMed 9490718

Publications 1996

Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
PubMed 8798641

Publications 1995

Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
PubMed 7768953

Singer-Krüger B, Stenmark H, Zerial M (1995)
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
PubMed 8586662

Stenmark H, Bucci C, Zerial M (1995)
Expression of Rab GTPases using recombinant vaccinia viruses
Methods Enzymol, 257, 155-64
PubMed 8583918

Stenmark H, Vitale G, Ullrich O, Zerial M (1995)
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
PubMed 8521472

Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
PubMed 8824393

Publications 1994

de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
PubMed 8043272

Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
PubMed 8163546

Stenmark H, Parton RG, Steele-Mortimer O, Lütcke A, Gruenberg J, Zerial M (1994)
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
EMBO J, 13 (6), 1287-96
PubMed 8137813

Stenmark H, Valencia A, Martinez O, Ullrich O, Goud B, Zerial M (1994)
Distinct structural elements of rab5 define its functional specificity
EMBO J, 13 (3), 575-83
PubMed 8313902

Publications 1993

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
PubMed 8418864

Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690

Zerial M, Stenmark H (1993)
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
PubMed 8257602

Publications 1992

Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
PubMed 1639497

Madshus IH, Stenmark H (1992)
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
PubMed 1378368

Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3), 619-25
PubMed 1536643

Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382

Publications 1991

Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632

Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012

Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
PubMed 2040642

Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
PubMed 1646374

Publications 1990

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980

Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
PubMed 1696341

Publications 1989

McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
PubMed 2684631

OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751

Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882

Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
PubMed 2479538

Publications 1988

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
PubMed 3072713

Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666