High throughput DNA sequencing of T-cell and B-cell receptors on single cell and bulk cell levels
Transcriptome analysis of disease relevant effector immune cells (B cells and T cells)
Development of novel diagnostic tools; detection of disease specific effector cells in peripheral blood and development of serological assays for immunoglobulin detection
Characterization of models for breakage of B-cell tolerance by use of immunoglobulin knock-in mouse model • Characterization of the autoimmune B-cell response and biology of the autoantigen transglutaminase 2
Lindeman I, Høydahl LS, Christophersen A, Risnes LF, Jahnsen J, Lundin KEA, Sollid LM, Iversen R(2024) Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease Cell Rep, 43(4), 114045(in press) DOI 10.1016/j.celrep.2024.114045, PubMed 38578826
Risnes LF, Reims HM, Doyle RM, Qiao SW, Sollid LM, Lundin KEA, Christophersen A(2024) Gluten-free diet induces rapid changes in phenotype and survival properties of gluten-specific T cells in celiac disease Gastroenterology(in press) DOI 10.1053/j.gastro.2024.03.027, PubMed 38552723
Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM(2024) Correction to: Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis Adv Sci (Weinh), e2400894(in press) DOI 10.1002/advs.202400894, PubMed 38477397