Thomas Helle-Valle
Position:	MD, PhD Student
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Scientific projects

Project:

Global and regional parameters of myocardial viability by myocardial speckle tracking echocardiography – an experimental and clinical study

Supervisors:

Otto A. Smiseth, Thor Edvardsen (co-supervisor)

Collaborators:

Otto A. Smiseth, Halfdan Ihlen, Thor Edvardsen, Trond Vartdal, Eirik Pettersen, Anders Opdahl, Espen Remme, Ola Gjesdal (Department of Cardiology, Rikshospitalet); Brage Amundsen, Jonas Crosby, Hans Torp (NTNU, Trondheim). Boaz D. Rosen, João A.C. Lima (John Hopkins University Hospital, Baltimore, USA)

Aim:

To study the effects of myocardial ischemia on regional and global LV deformation and to develop new echocardiographic methods for quantification of regional and global dysfunction

Author network for Thomas Helle-Valle by COREMINE medical

Publications 2009

Helle-Valle T, Remme EW, Lyseggen E, Pettersen E, Vartdal T, Opdahl A, Smith HJ, Osman NF, Ihlen H, Edvardsen T, Smiseth OA (2009)
Clinical assessment of left ventricular rotation and strain: a novel approach for quantification of function in infarcted myocardium and its border zones
Am J Physiol Heart Circ Physiol, 297 (1), H257-67
PubMed 19395547

Lyseggen E, Vartdal T, Remme EW, Helle-Valle T, Pettersen E, Opdahl A, Edvardsen T, Smiseth OA (2009)
A novel echocardiographic marker of end systole in the ischemic left ventricle: "tug of war" sign
Am J Physiol Heart Circ Physiol, 296 (3), H645-54
PubMed 19122168

Opdahl A, Remme EW, Helle-Valle T, Lyseggen E, Vartdal T, Pettersen E, Edvardsen T, Smiseth OA (2009)
Determinants of left ventricular early-diastolic lengthening velocity: independent contributions from left ventricular relaxation, restoring forces, and lengthening load
Circulation, 119 (19), 2578-86
PubMed 19414640

Remme EW, Lyseggen E, Helle-Valle T, Pettersen E, Ragnarsson A, Ihlen H, Edvardsen T, Smiseth OA, Opdahl A, Vartdal T, Ljosland M (2009)
Response to Letter Regarding Article, "Mechanisms of Preejection and Postejection Velocity Spikes in Left Ventricular Myocardium: Interaction Between Wall Deformation and Valve Events"
Circulation, 119 (6), E205

Rosen BD, Fernandes VR, Nasir K, Helle-Valle T, Jerosch-Herold M, Bluemke DA, Lima JA (2009)
Age, increased left ventricular mass, and lower regional myocardial perfusion are related to greater extent of myocardial dyssynchrony in asymptomatic individuals: the multi-ethnic study of atherosclerosis
Circulation, 120 (10), 859-66
PubMed 19704101

Publications 2008

Crosby J, Amundsen BH, Helle-Valle T, Steen PA, Torp H (2008)
A new tissue Doppler method for examination of left ventricular rotation
Ultrasound Med Biol, 34 (11), 1741-51
PubMed 18547711

Gjesdal O, Helle-Valle T, Hopp E, Lunde K, Vartdal T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2008)
Noninvasive separation of large, medium, and small myocardial infarcts in survivors of reperfused ST-elevation myocardial infarction: a comprehensive tissue Doppler and speckle-tracking echocardiography study
Circ Cardiovasc Imaging, 1 (3), 189-96, 2 p following 196
PubMed 19808542

Opdahl A, Helle-Valle T, Remme EW, Vartdal T, Pettersen E, Lunde K, Edvardsen T, Smiseth OA (2008)
Apical rotation by speckle tracking echocardiography: a simplified bedside index of left ventricular twist
J Am Soc Echocardiogr, 21 (10), 1121-8
PubMed 18760568

Remme EW, Lyseggen E, Helle-Valle T, Opdahl A, Pettersen E, Vartdal T, Ragnarsson A, Ljosland M, Ihlen H, Edvardsen T, Smiseth OA (2008)
Mechanisms of preejection and postejection velocity spikes in left ventricular myocardium: interaction between wall deformation and valve events
Circulation, 118 (4), 373-80
PubMed 18606917

Publications 2007

Gjesdal O, Hopp E, Vartdal T, Lunde K, Helle-Valle T, Aakhus S, Smith HJ, Ihlen H, Edvardsen T (2007)
Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
Clin Sci (Lond), 113 (6), 287-96
PubMed 17501720

Pettersen E, Helle-Valle T, Edvardsen T, Lindberg H, Smith HJ, Smevik B, Smiseth OA, Andersen K (2007)
Contraction pattern of the systemic right ventricle shift from longitudinal to circumferential shortening and absent global ventricular torsion
J Am Coll Cardiol, 49 (25), 2450-6
PubMed 17599609

Vartdal T, Brunvand H, Pettersen E, Smith HJ, Lyseggen E, Helle-Valle T, Skulstad H, Ihlen H, Edvardsen T (2007)
Early prediction of infarct size by strain Doppler echocardiography after coronary reperfusion
J Am Coll Cardiol, 49 (16), 1715-21
PubMed 17448374

Publications 2006

Amundsen BH, Helle-Valle T, Edvardsen T, Torp H, Crosby J, Lyseggen E, Støylen A, Ihlen H, Lima JA, Smiseth OA, Slørdahl SA (2006)
Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging
J Am Coll Cardiol, 47 (4), 789-93
PubMed 16487846

Edvardsen T, Helle-Valle T, Smiseth OA (2006)
Systolic dysfunction in heart failure with normal ejection fraction: speckle-tracking echocardiography
Prog Cardiovasc Dis, 49 (3), 207-14
PubMed 17084180

Publications 2005

Helle-Valle T, Crosby J, Edvardsen T, Lyseggen E, Amundsen BH, Smith HJ, Rosen BD, Lima JA, Torp H, Ihlen H, Smiseth OA (2005)
New noninvasive method for assessment of left ventricular rotation: speckle tracking echocardiography
Circulation, 112 (20), 3149-56
PubMed 16286606

Lyseggen E, Skulstad H, Helle-Valle T, Vartdal T, Urheim S, Rabben SI, Opdahl A, Ihlen H, Smiseth OA (2005)
Myocardial strain analysis in acute coronary occlusion: a tool to assess myocardial viability and reperfusion
Circulation, 112 (25), 3901-10
PubMed 16365210

Publications 1995

Helle-Valle T (1995)
[Health services in Nepal--much ado, little health]
Tidsskr Nor Laegeforen, 115 (6), 736-8
PubMed 7900140

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