PubMed registered articles
Kirsten Sandvig
Publications by Kirsten Sandvig
240 publications found
Publications in press
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Inhibitors of Intravesicular Acidification Protect Against Shiga Toxin in a pH-Independent Manner
Traffic (in press)
PubMed 22132807
Publications 2011
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Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
Biochem Biophys Res Commun, 408 (3), 405-10
PubMed 21513701 -
Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
Traffic, 12 (10), 1417-31
PubMed 21722281 -
Shiga toxin and its use in targeted cancer therapy and imaging
Microb Biotechnol, 4 (1), 32-46
PubMed 21255370 -
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
PubMed 21779335 -
Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
Nano Today, 6 (2), 176-185 -
Role of phospholipase a(2) in retrograde transport of ricin
Toxins (Basel), 3 (9), 1203-19
PubMed 22069763 -
Clathrin-independent endocytosis: mechanisms and function
Curr Opin Cell Biol, 23 (4), 413-20
PubMed 21466956 -
Comment on "short ligands affect modes of QD uptake and elimination in human cells"
ACS Nano, 5 (10), 7690; author reply 7691-2
PubMed 22023400 -
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
Biochem J, 436 (2), 371-85
PubMed 21388347 -
Protein C mutation (A267T) results in ER retention and unfolded protein response activation
PLoS One, 6 (8), e24009
PubMed 21901152 -
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
FEMS Immunol Med Microbiol, 61 (1), 63-75
PubMed 21054580
Publications 2010
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Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
Cell Microbiol, 12 (12), 1809-20
PubMed 20690924 -
Interplay between toxin transport and flotillin localization
PLoS One, 5 (1), e8844
PubMed 20107503 -
Endocytosis and retrograde transport of Shiga toxin
Toxicon, 56 (7), 1181-5
PubMed 19951719 -
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
FEBS Lett, 584 (12), 2626-34
PubMed 20385131 -
New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
Nanomedicine, 6 (6), 730-7
PubMed 20570639 -
Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
BMC Cell Biol, 11, 67
PubMed 20815936 -
The Intracellular Journey of Shiga Toxins
The Open Toxinology Journal, 3, 3-12
PublikaID 24 -
Shiga toxin increases formation of clathrin-coated pits through Syk kinase
PLoS One, 5 (7), e10944
PubMed 20668539
Publications 2009
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Sorting nexin 8 regulates endosome-to-Golgi transport
Biochem Biophys Res Commun, 390 (1), 109-14
PubMed 19782049 -
Ligand-specific induction of endocytosis in taste receptor cells
J Exp Biol, 212 (Pt 1), 42-9
PubMed 19088209 -
Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
PublikaID 29 -
Quantum dot bioconjugates: Uptake into cells and induction of changes in normal cellular transport
P SOC PHOTO-OPT INS, 7189, 71890T -
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
Traffic, 10 (7), 868-82
PubMed 19453975 -
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
PubMed 19529763 -
?-arrestins attenuate p38-mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
PubMed 19159388 -
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
PubMed 19289168
Publications 2008
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Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
Histochem Cell Biol, 129 (3), 267-76
PubMed 18193449 -
Cell biology: Viruses in camouflage
Nature, 453 (7194), 466-7
PubMed 18497813 -
Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
Nano Lett, 8 (7), 1858-65
PubMed 18570482 -
The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking
Mol Biol Cell, 19 (1), 95-104
PubMed 17959827
Publications 2007
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The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Exp Cell Res, 313 (8), 1696-709
PubMed 17382318 -
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
PubMed 17407762 -
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
Eur J Cell Biol, 86 (7), 405-15
PubMed 17601634 -
Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
Virology, 369 (1), 105-18
PubMed 17714753 -
Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
Traffic, 8 (3), 297-309
PubMed 17319803 -
Polyunsaturated fatty acids regulate Shiga toxin transport
Biochem Biophys Res Commun, 364 (2), 283-8
PubMed 17942073 -
Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
J Biol Chem, 282 (22), 16317-28
PubMed 17403690 -
SNX1 and SNX2 mediate retrograde transport of Shiga toxin
Biochem Biophys Res Commun, 358 (2), 566-70
PubMed 17498660
Publications 2006
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Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
Traffic, 7 (9), 1243-53
PubMed 16919154 -
Shiga toxin regulates its entry in a Syk-dependent manner
Mol Biol Cell, 17 (3), 1096-109
PubMed 16371508 -
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
Mol Biol Cell, 17 (4), 1664-75
PubMed 16452630 -
Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
Traffic, 7 (6), 663-72
PubMed 16683916
Publications 2005
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Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
Traffic, 6 (2), 144-56
PubMed 15634214 -
Cellular internalization of cytolethal distending toxin: a new end to a known pathway
Cell Microbiol, 7 (7), 921-34
PubMed 15953025 -
Caveolae: stable membrane domains with a potential for internalization
Traffic, 6 (9), 720-4
PubMed 16101676 -
Delivery into cells: lessons learned from plant and bacterial toxins
Gene Ther, 12 (11), 865-72
PubMed 15815697 -
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
Biochem Biophys Res Commun, 329 (2), 465-73
PubMed 15737610 -
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
Toxicon, 46 (8), 900-6
PubMed 16260019 -
The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
FEBS J, 272 (16), 4103-13
PubMed 16098193
Publications 2004
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Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
J Cell Sci, 117 (Pt 11), 2321-31
PubMed 15126632 -
Pathways followed by protein toxins into cells
Int J Med Microbiol, 293 (7-8), 483-90
PubMed 15149022
Publications 2003
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Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
J Biol Chem, 278 (3), 1991-7
PubMed 12419802 -
Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
Proc Natl Acad Sci U S A, 100 (9), 5175-80
PubMed 12682302 -
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
J Biol Chem, 278 (37), 35850-5
PubMed 12847103 -
Cholera toxin internalization and intoxication - Reply
J. Cell Sci., 116 (3), 432-433 -
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-552 -
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-52
PubMed 12839497 -
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
J Biol Chem, 278 (5), 3331-8
PubMed 12424246 -
Caveolae: anchored, multifunctional platforms in the lipid ocean
Trends Cell Biol, 13 (2), 92-100
PubMed 12559760 -
Cholesterol loading induces a block in the exit of VSVG from the TGN
Traffic, 4 (11), 772-84
PubMed 14617359
Publications 2002
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Membrane ruffling and macropinocytosis in A431 cells require cholesterol
J Cell Sci, 115 (Pt 14), 2953-62
PubMed 12082155 -
Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
J Cell Sci, 115 (Pt 17), 3449-56
PubMed 12154075 -
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
J Biol Chem, 277 (21), 18954-60
PubMed 11886870 -
Pathways followed by ricin and Shiga toxin into cells
Histochem Cell Biol, 117 (2), 131-41
PubMed 11935289 -
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
FEBS Lett, 529 (1), 49-53
PubMed 12354612 -
Membrane traffic exploited by protein toxins
Annu Rev Cell Dev Biol, 18, 1-24
PubMed 12142266
Publications 2001
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Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
Traffic, 2 (1), 26-36
PubMed 11208166 -
Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
Mol Biol Cell, 12 (7), 2099-107
PubMed 11452006 -
Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
J Cell Sci, 114 (Pt 2), 335-43
PubMed 11148135 -
Shiga toxins
Toxicon, 39 (11), 1629-35
PubMed 11595626 -
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
PubMed 11340584 -
Internalization of cholera toxin by different endocytic mechanisms
J Cell Sci, 114 (Pt 20), 3737-47
PubMed 11707525
Publications 2000
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Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
PubMed 10660606 -
Penetration of protein toxins into cells
Curr Opin Cell Biol, 12 (4), 407-13
PubMed 10873820 -
Endosome to Golgi transport of ricin is regulated by cholesterol
Mol Biol Cell, 11 (12), 4205-16
PubMed 11102518 -
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
J Cell Sci, 113 ( Pt 7), 1213-21
PubMed 10704372 -
Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
Mol Biol Cell, 11 (2), 481-95
PubMed 10679008 -
Ricin transport into cells: studies of endocytosis and intracellular transport
Int J Med Microbiol, 290 (4-5), 415-20
PubMed 11111920 -
Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
PubMed 10961444 -
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
EMBO J, 19 (22), 5943-50
PubMed 11080141 -
Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
PubMed 10913830 -
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
PubMed 10956397 -
Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
Exp Cell Res, 261 (1), 111-8
PubMed 11082281
Publications 1999
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Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
PubMed 10096543 -
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
PubMed 10198050 -
Endocytosis and intracellular transport of ricin: recent discoveries
FEBS Lett, 452 (1-2), 67-70
PubMed 10376680 -
Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
J Cell Sci, 112 ( Pt 22), 3899-909
PubMed 10547351 -
Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
Mol Biol Cell, 10 (1), 179-95
PubMed 9880335
Publications 1998
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Phacoemulsification in eyes with pseudoexfoliation
J Cataract Refract Surg, 24 (6), 787-92
PubMed 9642589 -
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
J Cell Biol, 140 (3), 553-63
PubMed 9456316 -
Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
FEBS Lett, 431 (2), 200-4
PubMed 9708902 -
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
J Cell Sci, 111 ( Pt 6), 825-32
PubMed 9472010
Publications 1997
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Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
PubMed 9111051 -
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
PubMed 9192018
Publications 1996
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Comparison of a diffractive bifocal and a monofocal intraocular lens
J Cataract Refract Surg, 22 (4), 446-51
PubMed 8733848 -
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
PubMed 8831568 -
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
PubMed 8901582 -
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
PubMed 8885234 -
Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
Physiol Rev, 76 (4), 949-66
PubMed 8874490 -
Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
Eur J Cell Biol, 69 (4), 343-50
PubMed 8741216 -
Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
J Cell Sci, 109 ( Pt 7), 1655-65
PubMed 8832388
Publications 1995
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CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168 -
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
PubMed 7737376 -
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
PubMed 7738018 -
Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
Exp Cell Res, 217 (1), 157-68
PubMed 7867714 -
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1), 285-9
PubMed 7646457 -
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
Eur J Cell Biol, 66 (4), 309-23
PubMed 7544728
Publications 1994
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Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
J Biol Chem, 269 (28), 18607-15
PubMed 8034609 -
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
PubMed 7523112 -
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447 -
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146 -
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
PubMed 8027186 -
Endocytosis and intracellular sorting of ricin and Shiga toxin
FEBS Lett, 346 (1), 99-102
PubMed 8206167 -
Endocytosis without clathrin
Trends Cell Biol, 4 (8), 275-7
PubMed 14731589 -
ENTRY OF SHIGA TOXIN INTO CELLS
ZBL BAKT S, 24, 365-374 -
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
PubMed 7511061
Publications 1993
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Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
J Cell Biol, 123 (1), 89-97
PubMed 8408209 -
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
J Cell Biol, 121 (1), 61-72
PubMed 8458873 -
Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
Eur J Cell Biol, 62 (2), 362-71
PubMed 7925492 -
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
PubMed 8411117 -
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493 -
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
PubMed 8392658 -
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
PubMed 8347933 -
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
PubMed 8224494 -
Multivesicular bodies in HEp-2 cells are maturing endosomes
Eur J Cell Biol, 61 (2), 208-24
PubMed 8223712 -
Are caveolae involved in clathrin-independent endocytosis?
Trends Cell Biol, 3 (8), 249-51
PubMed 14731741
Publications 1992
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Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320 -
Internalization efficiency of the transferrin receptor
Exp Cell Res, 199 (1), 19-28
PubMed 1735458 -
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
PubMed 1324134 -
Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
J Cell Biol, 119 (2), 259-72
PubMed 1400572 -
Protein toxins: mode of action and cell entry
Biochem Soc Trans, 20 (4), 724-7
PubMed 1487049 -
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
Nature, 358 (6386), 510-2
PubMed 1641040 -
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
Exp Cell Res, 200 (2), 253-62
PubMed 1572394
Publications 1991
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The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
J Cell Biol, 113 (4), 731-41
PubMed 1673969 -
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
PubMed 2046087 -
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632 -
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
PubMed 1791187 -
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345 -
Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
J Cell Biol, 115 (4), 971-81
PubMed 1955466 -
Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
J Cell Biol, 113 (3), 553-62
PubMed 1901867 -
Endocytosis without clathrin (a minireview)
Cell Biol Int Rep, 15 (1), 3-8
PubMed 1900741 -
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
PubMed 2040642 -
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131
Publications 1990
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Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980 -
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
PubMed 1696341 -
Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
J Biol Chem, 265 (11), 6382-8
PubMed 1969411 -
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
PubMed 2163200 -
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
Eur J Cell Biol, 51 (1), 96-109
PubMed 2328741
Publications 1989
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Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
PubMed 2689197 -
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
PubMed 2684631 -
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440 -
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283 -
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677 -
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882 -
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751 -
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
PubMed 2564398 -
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
PubMed 2575206 -
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
PubMed 2479538 -
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970 -
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
PubMed 2818647 -
The ways of endocytosis
Int Rev Cytol, 117, 131-77
PubMed 2573583 -
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460
Publications 1988
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Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
PubMed 3368193 -
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019 -
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
PubMed 3072713 -
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
PubMed 2908634 -
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517 -
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582 -
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
PubMed 2893802 -
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666 -
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
PubMed 2892843
Publications 1987
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Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
PubMed 3032992 -
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
PubMed 3571337 -
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141 -
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
PubMed 3624315 -
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
PubMed 3606992 -
Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
Infect Immun, 55 (2), 298-303
PubMed 3542829 -
Pseudomonas toxin binds triton X-114 at low pH
Biochem J, 245 (3), 899-901
PubMed 3117052 -
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
PubMed 2887575 -
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
PubMed 3624314 -
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
PubMed 3622628 -
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
PubMed 3036553
Publications 1986
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Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100 -
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
PubMed 3949885 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015 -
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644 -
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563 -
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160 -
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
PubMed 3001103
Publications 1985
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Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
PubMed 3844014 -
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
PubMed 2995095 -
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
PubMed 4041483 -
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869 -
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191 -
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
PubMed 2990449 -
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
PubMed 3930519 -
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357 -
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595 -
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
PubMed 2863159
Publications 1984
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Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
PubMed 6097029 -
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
PubMed 6325467 -
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
PubMed 6092049 -
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
PubMed 6331401 -
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
PubMed 6707104 -
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140 -
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
PubMed 6699094 -
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858 -
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
PubMed 6707099
Publications 1983
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Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
PubMed 6318763 -
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
PubMed 6652111 -
DANCYLCADAVERINE ELIMINATES CALMODULIN STIMULATION OF PHOSPHODIESTERASE
Biochem. Biophys. Res. Commun., 117 (2), 562-567
Publications 1982
-
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
PubMed 6178935 -
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144 -
ISOLATION AND CHARACTERIZATION OF VISCUMIN, A TOXIC LECTIN FROM VISCUM-ALBUM L (MISTLETOE)
J. Biol. Chem., 257 (22), 3263-3270 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634 -
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145 -
ACTION OF VISCUMIN, A TOXIC LECTIN FROM MISTLETOE, ON CELLS IN CULTURE
J. Biol. Chem., 257 (22), 3271-3277 -
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588
Publications 1981
-
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699 -
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
PubMed 7306026
Publications 1980
-
[Intracellular mediators for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (15), 1021-23
PubMed 6250248 -
Corneal Changes During Chloroquine Treatment: An investigation of 70 patients with chronic rheumatoid arthritis receiving chloroquine treatment
Scand J Rheumatol, 9 (1), 150-6
PubMed 19919350 -
[Receptors for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
PubMed 6250247 -
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
PubMed 7462324
Publications 1979
-
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
PubMed 446525 -
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
PubMed 508328
Publications 1978
-
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
PubMed 732310 -
Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
FEBS Lett, 89 (2), 233-6
PubMed 658411 -
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
PubMed 639792 -
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
PubMed 620666 -
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
PubMed 78847
Publications 1977
-
MODECCIN - PLANT TOXIN INHIBITING PROTEIN-SYNTHESIS
Biochem. Biophys. Res. Commun., 79 (4), 1176-1183 -
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
PubMed 603653
Publications 1976




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