Ashish Jain
Position: Postdoc (Helse Sør-øst)
Phone: +47 22 78 19 15
Email:


Publications by Ashish Jain (Full list)

Microenvironmental autophagy promotes tumour growth.
Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE.
Nature. 2017 Jan 11. doi: 10.1038/nature20815. [Epub ahead of print]
PMID: 28077876

Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy.
Kimura T, Jia J, Kumar S, Choi SW, Gu Y, Mudd M, Dupont N, Jiang S, Peters R, Farzam F, Jain A, Lidke KA, Adams CM, Johansen T, Deretic V.
EMBO J. 2017 Jan 4;36(1):42-60.
PMID: 27932448

TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation.
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V.
J Cell Sci. 2016 Oct 1;129(19):3562-3573.
PMID: 27562068

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.
Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V.
Dev Cell. 2016 Sep 28. pii: S1534-5807(16)30568-8. doi: 10.1016/j.devcel.2016.08.003.
PMID: 27693506

TRIM-Directed Selective Autophagy Regulates Immune Activation.
Kimura T, Jain A, Choi SW, Mandell MA, Johansen T, Deretic V.
Autophagy. 2016 Mar 16:0. [Epub ahead of print]
PMID: 26983397

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer.
Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP.
Nat Commun. 2016 Jan 12;7:10318. doi: 10.1038/ncomms10318.
PMID: 26754771 Free PMC Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, ..........., Jain A, Rusten TE, ............., Zughaier SM.
Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356.

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.
Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V

Cell Biol. 2015 Sep 14;210(6):973-89.

PMID: 26347139 Free PMC Article


p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB.
Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T.
J Biol Chem. 2015 Jun 12;290(24):14945-62. doi: 10.1074/jbc.M115.656116. Epub 2015 Apr 30.
PMID: 25931115 Free PMC Article

SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors.
Bertrand M, Petit V, Jain A, Amsellem R, Johansen T, Larue L, Codogno P, Beau I.
Cell Cycle. 2015;14(3):364-74. doi: 10.4161/15384101.2014.987619.
PMID: 25496309

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy.
Borel S, Robert-Hebmann V, Alfaisal J, Jain A, Faure M, Espert L, Chaloin L, Paillart JC, Johansen T, Biard-Piechaczyk M.
AIDS. 2015 Jan 28;29(3):275-86.
PMID: 25490467

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V.
Dev Cell. 2014 Aug 25;30(4):394-409. doi: 10.1016/j.devcel.2014.06.013. Epub 2014 Aug 7.
PMID: 25127057 Free PMC Article

TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction.
Mandell MA, Kimura T, Jain A, Johansen T, Deretic V.
Autophagy. 2014;10(12):2387-8. doi: 10.4161/15548627.2014.984278.
PMID: 25587751 Free PMC Article

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.
Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.
J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.
PMID: 23043107 Free PMC Article

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.
J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.
PMID:  20452972 Free PMC Article

 

 

Publications by Ashish Jain (Institute database)

 

Publications 2016

Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V (2016)
TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis
Dev Cell, 39 (1), 13-27
PubMed 27693506

Kimura T, Jain A, Choi SW, Mandell MA, Johansen T, Deretic V (2016)
TRIM-Directed Selective Autophagy Regulates Immune Activation
Autophagy, 0 (in press)
PubMed 26983397

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 12 (1), 1-222
PubMed 26799652

Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2016)
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 129 (19), 3562-3573
PubMed 27562068

Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP (2016)
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
Nat Commun, 7, 10318
PubMed 26754771

Publications 2015

Bertrand M, Petit V, Jain A, Amsellem R, Johansen T, Larue L, Codogno P, Beau I (2015)
SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors
Cell Cycle, 14 (3), 364-74
PubMed 25496309

Borel S, Robert-Hebmann V, Alfaisal J, Jain A, Faure M, Espert L, Chaloin L, Paillart JC, Johansen T, Biard-Piechaczyk M (2015)
HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy
AIDS, 29 (3), 275-86
PubMed 25490467

Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T (2015)
p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
J Biol Chem, 290 (24), 14945-62
PubMed 25931115

Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V (2015)
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
J Cell Biol, 210 (6), 973-89
PubMed 26347139

Publications 2014

Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V (2014)
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
Dev Cell, 30 (4), 394-409
PubMed 25127057

Publications 2012

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T (2012)
ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs
J Biol Chem, 287 (47), 39275-90
PubMed 23043107