Author network for Edward Leithe by COREMINE medical

Publications in press

Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E
Endocytosis and post-endocytic sorting of connexins
Biochim Biophys Acta (in press)
PubMed 21996040

Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer (in press)
PubMed 21866551

Publications 2012

Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E (2012)
The Gap Junction Channel Protein Connexin 43 Is Covalently Modified and Regulated by SUMOylation
J Biol Chem, 287 (19), 15851-61
PubMed 22411987

Publications 2011

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
PubMed 21564451

Mollerup S, Hofgaard JP, Braunstein TH, Kjenseth A, Leithe E, Rivedal E, Holstein-Rathlou NH, Nielsen MS (2011)
Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
Cell Commun Adhes, 18 (4), 57-65
PubMed 21936631

Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE (2011)
DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
Epigenetics, 6 (5), 602-9
PubMed 21406965

Publications 2010

Kjenseth A, Fykerud T, Rivedal E, Leithe E (2010)
Regulation of gap junction intercellular communication by the ubiquitin system
Cell Signal, 22 (9), 1267-73
PubMed 20206687

Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E (2010)
Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
Toxicol Appl Pharmacol, 247 (1), 10-7
PubMed 20510257

Rivedal E, Witz G, Leithe E (2010)
Gap junction intercellular communication and benzene toxicity
Chem Biol Interact, 184 (1-2), 229-32
PubMed 19932693

Publications 2009

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888

Sirnes S, Kjenseth A, Leithe E, Rivedal E (2009)
Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
Biochem Biophys Res Commun, 382 (1), 41-5
PubMed 19258009

Publications 2008

Rivedal E, Leithe E (2008)
The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
Toxicol Appl Pharmacol, 232 (3), 463-8
PubMed 18723040

Sirnes S, Leithe E, Rivedal E (2008)
The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
Biochem Biophys Res Commun, 373 (4), 597-601
PubMed 18601906

Publications 2007

Leithe E, Rivedal E (2007)
Ubiquitination of gap junction proteins
J Membr Biol, 217 (1-3), 43-51
PubMed 17657522

Publications 2006

Leithe E, Brech A, Rivedal E (2006)
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
PubMed 16162097

Leithe E, Sirnes S, Omori Y, Rivedal E (2006)
Downregulation of gap junctions in cancer cells
Crit Rev Oncog, 12 (3-4), 225-56
PubMed 17425504

Publications 2005

Rivedal E, Leithe E (2005)
Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells
Exp Cell Res, 302 (2), 143-52
PubMed 15561096

Publications 2004

Leithe E, Rivedal E (2004)
Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43
J Cell Sci, 117 (Pt 7), 1211-20
PubMed 14970263

Leithe E, Rivedal E (2004)
Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment
J Biol Chem, 279 (48), 50089-96
PubMed 15371442

Publications 2003

Cruciani V, Leithe E, Mikalsen SO (2003)
Ilimaquinone inhibits gap-junctional communication prior to Golgi fragmentation and block in protein transport
Exp Cell Res, 287 (1), 130-42
PubMed 12799189

Leithe E, Cruciani V, Sanner T, Mikalsen SO, Rivedal E (2003)
Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C
Carcinogenesis, 24 (7), 1239-45
PubMed 12807762

Publications 2002

Mallardo M, Leithe E, Schleich S, Roos N, Doglio L, Krijnse Locker J (2002)
Relationship between vaccinia virus intracellular cores, early mRNAs, and DNA replication sites
J Virol, 76 (10), 5167-83
PubMed 11967332