Research interests

The projects are divided into two main lines of research:

1. Technical development and the striving for optimum instrumentation and protocols in morphological research.

• The studies are particularly directed towards methods for studies of ultrastructure and molecular distribution in tissues samples. 
• The main goal is to enable studies of tissues close to the native state.

2. The use of these methods to study the molecular composition and cell/matrix interactions in connective tissues, particularly bone and cartilage in animal models.

• A central hypothesis is that knowledge obtained in such studies will provide data of crucial importance for the understanding of serious chronic diseases of skeletal tissues, like osteoporosis (OP) and osteoarthritis. 
• In the longer perspective, the data will form the basis for new treatment strategies and ultimately, effective preventive measures against the diseases. 

The research is conducted in two larger networks, the OSTEOGENE consortium supported by EU, and the Oslo Cartilage Research Group.