
| Kirsten Muri Boberg | |
| Position: | Professor, Head of Section, MD, PhD |
| Phone: | +47 23 07 24 68 |
| Email: | |
Author network for Kirsten Muri Boberg by COREMINE medical
Publications in press
Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology (in press)
PubMed 22821403
Update on primary sclerosing cholangitis
J Hepatol (in press)
PubMed 23603668
Association Between Reduced Levels of Alkaline Phosphatase and Survival Times of Patients With Primary Sclerosing Cholangitis
Clin Gastroenterol Hepatol (in press)
PubMed 23353641
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nat Genet (in press)
PubMed 23603763
Publications 2013
Liver transplantation for nonresectable liver metastases from colorectal cancer
Ann Surg, 257 (5), 800-6
PubMed 23360920
Immunosuppression after liver transplantation for primary sclerosing cholangitis influences activity of inflammatory bowel disease
Clin Gastroenterol Hepatol, 11 (5), 517-23
PubMed 23333218
Publications 2012
Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
Epigenetics, 7 (11), 1249-57
PubMed 22983262
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
PubMed 22521342
Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
Liver Transpl, 18 (12), 1421-9
PubMed 22767413
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transpl, 18 (7), 839-49
PubMed 22407878
Inflammatory bowel disease in patients with primary sclerosing cholangitis: clinical characterization in liver transplanted and nontransplanted patients
Inflamm Bowel Dis, 18 (3), 536-45
PubMed 21456044
Colorectal neoplasia in patients with primary sclerosing cholangitis undergoing liver transplantation: a Nordic multicenter study
Scand J Gastroenterol, 47 (8-9), 1021-9
PubMed 22577871
High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasia
Aliment Pharmacol Ther, 35 (4), 451-7
PubMed 22221173
Publications 2011
Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
J Hepatol, 54 (2), 374-85
PubMed 21067838
Primary sclerosing cholangitis and malignancy
Best Pract Res Clin Gastroenterol, 25 (6), 753-64
PubMed 22117640
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
Hepatology, 53 (6), 1967-76
PubMed 21413052
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
Hepatology, 53 (6), 1977-85
PubMed 21425313
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
Nat Genet, 43 (1), 17-9
PubMed 21151127
[A man in his 60s with severe respiratory failure]
Tidsskr Nor Laegeforen, 131 (17), 1654-7
PubMed 21901039
Current consensus on the management of primary sclerosing cholangitis
Clin Res Hepatol Gastroenterol, 35 (12), 786-91
PubMed 21963085
Publications 2010
Diagnosis and management of primary sclerosing cholangitis
Hepatology, 51 (2), 660-78
PubMed 20101749
Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
Clin Transplant, 24 (5), E145-52
PubMed 20236290
Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
PLoS One, 5 (8), e12403
PubMed 20811628
Genome-wide association analysis in primary sclerosing cholangitis
Gastroenterology, 138 (3), 1102-11
PubMed 19944697
Update on primary sclerosing cholangitis
Dig Liver Dis, 42 (6), 390-400
PubMed 20172772
Primary sclerosing cholangitis
Best Pract Res Clin Gastroenterol, 24 (5), 655-66
PubMed 20955968
Validation of a cholangiographic prognostic model in primary sclerosing cholangitis
Endoscopy, 42 (9), 742-7
PubMed 20623444
Publications 2009
EASL Clinical Practice Guidelines: management of cholestatic liver diseases
J Hepatol, 51 (2), 237-67
PubMed 19501929
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Carcinogenesis, 30 (7), 1147-54
PubMed 19443904
[Liver transplantation in Norway through 25 years]
Tidsskr Nor Laegeforen, 129 (24), 2587-92
PubMed 20029553
Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases
Genes Immun, 10 (6), 601-5
PubMed 19387457
Publications 2008
The natural history of small-duct primary sclerosing cholangitis
Gastroenterology, 134 (4), 975-80
PubMed 18395078
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann Rheum Dis, 67 (9), 1287-91
PubMed 18065500
Simplified criteria for the diagnosis of autoimmune hepatitis
Hepatology, 48 (1), 169-76
PubMed 18537184
Autoantibodies in primary sclerosing cholangitis
World J Gastroenterol, 14 (24), 3781-91
PubMed 18609700
Gallbladder polyps in primary sclerosing cholangitis: not so benign
Curr Opin Gastroenterol, 24 (3), 395-9
PubMed 18408471
An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
Am J Gastroenterol, 103 (4), 1045; author reply 1045-6
PubMed 18397431
Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
Hepatology, 47 (1), 90-6
PubMed 18023027
Publications 2007
Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
J Hepatol, 46 (5), 899-906
PubMed 17383044
Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis
Genes Immun, 8 (3), 275-8
PubMed 17301827
Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis
Am J Gastroenterol, 102 (1), 115-21
PubMed 17100974
Genetic epidemiology of primary sclerosing cholangitis
World J Gastroenterol, 13 (41), 5421-31
PubMed 17907284
Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes
Tissue Antigens, 69 (2), 161-9
PubMed 17257319
Publications 2006
Diagnostic accuracy of magnetic resonance and endoscopic retrograde cholangiography in primary sclerosing cholangitis
Clin Gastroenterol Hepatol, 4 (4), 514-20
PubMed 16616358
ABO-incompatible deceased donor liver transplantation with the use of antigen-specific immunoadsorption and anti-CD20 monoclonal antibody
Clin Transplant, 20 (2), 265-8
PubMed 16640538
Diagnostic benefit of biliary brush cytology in cholangiocarcinoma in primary sclerosing cholangitis
J Hepatol, 45 (4), 568-74
PubMed 16879890
Analysis of MAdCAM-1 and ICAM-1 polymorphisms in 365 Scandinavian patients with primary sclerosing cholangitis
J Hepatol, 45 (5), 704-10
PubMed 16750586
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis
Gastroenterology, 131 (3), 781-7
PubMed 16952547
The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients
Tissue Antigens, 68 (1), 78-81
PubMed 16774544
No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis
Scand J Gastroenterol, 41 (5), 586-91
PubMed 16638702
Publications 2005
High-dose ursodeoxycholic acid in primary sclerosing cholangitis: a 5-year multicenter, randomized, controlled study
Gastroenterology, 129 (5), 1464-72
PubMed 16285948
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
Genes Immun, 6 (3), 271-3
PubMed 15759012
Publications 2004
Diagnosis and treatment of cholangiocarcinoma
Curr Gastroenterol Rep, 6 (1), 52-9
PubMed 14720454
Association of matrix metalloproteinase-1 and -3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients
J Hepatol, 41 (2), 209-14
PubMed 15288468
Publications 2003
Long-term effect of corticosteroid treatment in primary sclerosing cholangitis patients
Scand J Gastroenterol, 38 (9), 991-5
PubMed 14531538
Cholangiocarcinoma in situ in primary sclerosing cholangitis: diagnosis by brush cytology and treatment by liver transplantation
J Hepatol, 39 (3), 453
PubMed 12927935
[Fulminant liver failure in acute hepatitis B virus infection]
Tidsskr Nor Laegeforen, 123 (2), 172-4
PubMed 12607499
Hepatic and extrahepatic malignancies and primary sclerosing cholangitis
Gut, 52 (2), 165
PubMed 12524391
Publications 2002
Patients with small duct primary sclerosing cholangitis have a favourable long term prognosis
Gut, 51 (5), 731-5
PubMed 12377815
Prevalence and epidemiology of autoimmune hepatitis
Clin Liver Dis, 6 (3), 635-47
PubMed 12362572
Cholangiocarcinoma in primary sclerosing cholangitis: risk factors and clinical presentation
Scand J Gastroenterol, 37 (10), 1205-11
PubMed 12408527
Time-dependent Cox regression model is superior in prediction of prognosis in primary sclerosing cholangitis
Hepatology, 35 (3), 652-7
PubMed 11870380
Endoscopic treatment for primary sclerosing cholangitis?
J Hepatol, 36 (2), 278-9
PubMed 11830341
Publications 2001
The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis
Scand J Gastroenterol, 36 (8), 886-90
PubMed 11495087
Biliary dysplasia as a marker of cholangiocarcinoma in primary sclerosing cholangitis
J Hepatol, 34 (3), 360-5
PubMed 11322195
Association of the tumour necrosis factor alpha -308 but not the interleukin 10 -627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis
Gut, 49 (2), 288-94
PubMed 11454808
Epidemiology of primary sclerosing cholangitis
Best Pract Res Clin Gastroenterol, 15 (4), 553-62
PubMed 11492967
Primary sclerosing cholangitis is associated to an extended B8-DR3 haplotype including particular MICA and MICB alleles
Hepatology, 34 (4 Pt 1), 625-30
PubMed 11584356
Publications 2000
Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development
J Hepatol, 32 (3), 374-80
PubMed 10735605
Primary sclerosing cholangitis: challenges of a new millenium
Dig Liver Dis, 32 (9), 753-5
PubMed 11215553
Publications 1999
Is a prolonged bleeding time associated with an increased risk of hemorrhage after liver biopsy?
Thromb Haemost, 81 (3), 378-81
PubMed 10102464
Severe liver failure in exertional heat stroke
Scand J Gastroenterol, 34 (8), 824-7
PubMed 10499485
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations
Tissue Antigens, 53 (5), 459-69
PubMed 10372541
Publications 1998
Incidence and prevalence of primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis in a Norwegian population
Scand J Gastroenterol, 33 (1), 99-103
PubMed 9489916
Publications 1997
[Treatment of cholestatic liver diseases with ursodeoxycholic acid]
Tidsskr Nor Laegeforen, 117 (23), 3370-3
PubMed 9411890
Publications 1996
Features of autoimmune hepatitis in primary sclerosing cholangitis: an evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis of autoimmune hepatitis
Hepatology, 23 (6), 1369-76
PubMed 8675153
Publications 1995
Crohn disease and the myelodysplastic syndrome
Ann Intern Med, 122 (5), 395
PubMed 7847659
Publications 1994
Etiology and pathogenesis in primary sclerosing cholangitis
Scand J Gastroenterol Suppl, 204, 47-58
PubMed 7824878
Hepatobiliary disease in ulcerative colitis. An analysis of 18 patients with hepatobiliary lesions classified as small-duct primary sclerosing cholangitis
Scand J Gastroenterol, 29 (8), 744-52
PubMed 7973436
[Treatment of paracetamol poisoning. An indication for liver transplantation?]
Tidsskr Nor Laegeforen, 114 (10), 1199-203
PubMed 8209319
Publications 1991
[The significance of oxidized lipoproteins for the development of atherosclerosis. Antioxidants as a therapeutic alternative in atherosclerosis]
Tidsskr Nor Laegeforen, 111 (15), 1861-5
PubMed 1853321
Toxicity of sitosterol to human umbilical vein endothelial cells in vitro
Scand J Clin Lab Invest, 51 (6), 509-16
PubMed 1767244
Formation of novel C21-bile acids from cholesterol in the rat. Structure identification of the major Di- and trihydroxylated species
J Biol Chem, 266 (8), 4929-37
PubMed 2002039
Toxicity of oxygenated cholesterol derivatives toward cultured human umbilical vein endothelial cells
Arterioscler Thromb, 11 (2), 423-8
PubMed 1900193
Publications 1990
Apparent lack of conversion of sitosterol into C24-bile acids in humans
J Lipid Res, 31 (6), 1083-8
PubMed 2373958
Formation of C21 bile acids from plant sterols in the rat
J Biol Chem, 265 (14), 7967-75
PubMed 2335512
Publications 1989
Effect of sitosterol on the rate-limiting enzymes in cholesterol synthesis and degradation
Lipids, 24 (1), 9-12
PubMed 2747437
Difference in cytotoxicity of (22R)-cholest-5-ene-3 beta,7 alpha,22-triol and (22R)-cholest-5-ene-3 beta,7 beta,22-triol is not explained by different patterns of metabolites
J Steroid Biochem, 33 (6), 1087-9
PubMed 2615353
Dehydroxylation of a 7 beta-hydroxy-C27 plant sterol in rat liver
Biochim Biophys Acta, 1004 (3), 321-6
PubMed 2758026
Publications 1988
Content of sitosterol, cholestanol, and cholesterol in very low density lipoproteins of rat liver perfusate
Scand J Gastroenterol, 23 (4), 442-8
PubMed 3381065
Publications 1987
Normal activity of C27-steroid 26-hydroxylase in cultured sitosterolaemia fibroblasts
Scand J Clin Lab Invest, 47 (7), 701-4
PubMed 3685870
Publications 1986
Metabolism of 24-ethyl-4-cholesten-3-one and 24-ethyl-5-cholesten-3 beta-ol (sitosterol) after intraperitoneal injection in the rat
Scand J Clin Lab Invest Suppl, 184, 47-54
PubMed 3473613




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