Drude Merete Fugelseth
Position: Professor
Phone: +47-22850544
Email:

Academic Interests.

Main topics of interest are neonatology with focus on the newborn circulation, myocardial function and ventilation.

The research has been concentrated about myocardial function and circulation in healthy and sick term and preterm newborns. The transitional phase from fetal to newborn circulation is a vulnerable period for the newborn baby and has been of main interest.

As a leader of the research group "NeoCHIBS" (Neonatal Circulation, Heart, Infection and Brain Study Group), there are ongoing projects covering newer modalities for studying the myocardial function (Tissue Doppler Imaging),  macro- and microcirculation (ultrasound, laser Doppler, video microscopy and spectroscopy), studies of the cerebral circulation and MR in neonates treated with therapeutic hypothermia after birth asphyxia, and studies of spesific GBS-antibodies in mothers and the transmition to the baby.

The main aim of the circulatory studies is developing better methods for monitoring the sick newborn baby for improving supportive circulatory treatments.

Our research group is cooperating with several other departments within Oslo University Hospital, as well as other institutions and health regions in Norway and institutions in other countries. 

Courses taught

  • Medical students in 9th semester with special focus on neonatology

Background

  • 2011 Deputy Head of Institute for Clinical Medicine, Faculty of Medicine, University of Oslo (50 %) and Professor/consultant Dept. of Neonatal Intensive Care, Oslo University Hospital, Ullevål
  • 2007 Professor in Neonatology at University of Oslo
  • 2000 Doctor Medicinae, University of Oslo (Thesis: Ductus Venosus “Arantii” in the Newborn. “The forgotten vessel in neonatologi?” An ultrasonographic study.)
  • 1993 Consultant in Neonatology and Paediatric Cardiology, Oslo University Hospital
  • 1991 Spesialization in Paediatrics and Neonatology
  • 1981 MD University of Oslo
  • 1975 Educational Research, University of Oslo
  • 1972 Physiotherapist, National School of Physiotherapy

Awards

  • The director award of excellent research 2003

Collaboration

  • St. Michaels Hospital, University of Bristol, UK, Dept. of Biomedical Engineering, Linköping University, Linköping, Sweden, Dept. of Physiology, Temple University, Philadelphia PA, USA, Novartis Vaccines and Diagnostics, Siena, Italia, Dept. of Cardiothoracic Surgery, Oslo University Hospital, Ullevål, Oslo, Institute of Circulation and Medical Imaging, Norwegian Institute of Science and Technology, Trondheim, Dept. of Electronics and Telecommunications, Norwegian University of Science and Technology, St. Olavs Hospital, Trondheim, Dept. of Paediatrics, Vestfold Hospital Trust, Vestfold Hospital, Tønsberg, Department of Paediatrics, Sunnmore Public Health Enterprice, Aalesund, Norway

 

Author network for Drude Merete Fugelseth by COREMINE medical


Publications 2017

Fugelseth D (2017)
Measuring superior vena cava flow as part of echocardiography examinations performed by neonatologists
Acta Paediatr, 106 (1), 5-6
PubMed 27943434

Publications 2016

Brunvand L, Fugelseth D, Stensaeth KH, Dahl-Jørgensen K, Margeirsdottir HD (2016)
Early reduced myocardial diastolic function in children and adolescents with type 1 diabetes mellitus a population-based study
BMC Cardiovasc Disord, 16, 103
PubMed 27225446

Fredly S, Fugelseth D, Nygaard CS, Salerud EG, Stiris T, Kvernebo K (2016)
Noninvasive assessments of oxygen delivery from the microcirculation to skin in hypothermia-treated asphyxiated newborn infants
Pediatr Res, 79 (6), 902-6
PubMed 26854800

Fredly S, Nygaard CS, Skranes JH, Stiris T, Fugelseth D (2016)
Cooling Effect on Skin Microcirculation in Asphyxiated Newborn Infants with Increased C-Reactive Protein
Neonatology, 110 (4), 270-276
PubMed 27322828

Nestaas E, Støylen A, Fugelseth D (2016)
Speckle Tracking Using Gray-Scale Information from Tissue Doppler Recordings versus Regular Gray-Scale Recordings in Term Neonates
Ultrasound Med Biol, 42 (11), 2599-2605
PubMed 27576591

Publications 2015

Brigtsen AK, Jacobsen AF, Dedi L, Melby KK, Fugelseth D, Whitelaw A (2015)
Maternal Colonization with Group B Streptococcus Is Associated with an Increased Rate of Infants Transferred to the Neonatal Intensive Care Unit
Neonatology, 108 (3), 157-63
PubMed 26182960

Fredly S, Fugelseth D, Wester T, Häggblad E, Kvernebo K (2015)
Skin microcirculation in healthy term newborn infants--assessment of morphology, perfusion and oxygenation
Clin Hemorheol Microcirc, 59 (4), 309-22
PubMed 24002120

Helmer C, Skranes JH, Liestøl K, Fugelseth D (2015)
Using adrenaline during neonatal resuscitation may have an impact on serum cardiac troponin-T levels
Acta Paediatr, 104 (9), e378-83
PubMed 26032882

Skranes JH, Cowan FM, Stiris T, Fugelseth D, Thoresen M, Server A (2015)
Brain imaging in cooled encephalopathic neonates does not differ between four and 11 days after birth
Acta Paediatr, 104 (8), 752-8
PubMed 25824694

Publications 2014

Brigtsen AK, Dedi L, Melby KK, Holberg-Petersen M, Radtke A, Lyng RV, Andresen LL, Jacobsen AF, Fugelseth D, Whitelaw A (2014)
Comparison of PCR and serotyping of Group B Streptococcus in pregnant women: the Oslo GBS-study
J Microbiol Methods, 108, 31-5
PubMed 25447890

Eriksen BH, Nestaas E, Hole T, Liestøl K, Støylen A, Fugelseth D (2014)
Myocardial function in term and preterm infants. Influence of heart size, gestational age and postnatal maturation
Early Hum Dev, 90 (7), 359-64
PubMed 24794303

Nestaas E, Fugelseth D, Støylen A (2014)
Automated, objective and expert-independent assessment of the analyzability of strain and strain rate in tissue Doppler images in term neonates by analysis of beat-to-beat variation
Ultrasound Med Biol, 40 (3), 637-42
PubMed 24412174

Nestaas E, Skranes JH, Støylen A, Brunvand L, Fugelseth D (2014)
The myocardial function during and after whole-body therapeutic hypothermia for hypoxic-ischemic encephalopathy, a cohort study
Early Hum Dev, 90 (5), 247-52
PubMed 24612933

Skranes JH, Elstad M, Thoresen M, Cowan FM, Stiris T, Fugelseth D (2014)
Hypothermia makes cerebral resistance index a poor prognostic tool in encephalopathic newborns
Neonatology, 106 (1), 17-23
PubMed 24686318

Publications 2013

Eriksen BH, Husebekk A, Fugelseth D, Salberg KR, Lindemann R (2013)
A newborn with petechiae
Tidsskr Nor Laegeforen, 133 (7), 761-4
PubMed 23588181

Eriksen BH, Nestaas E, Hole T, Liestøl K, Støylen A, Fugelseth D (2013)
Myocardial function in premature infants: a longitudinal observational study
BMJ Open, 3 (3)
PubMed 23533215

Eriksen BH, Nestaas E, Hole T, Liestøl K, Støylen A, Fugelseth D (2013)
Longitudinal assessment of atrioventricular annulus excursion by grey-scale m-mode and colour tissue Doppler imaging in premature infants
Early Hum Dev, 89 (12), 977-82
PubMed 24080390

Kutzsche S, Fugelseth D (2013)
Ensuring safe neonatal care for newborn babies
Tidsskr Nor Laegeforen, 133 (3), 270-1
PubMed 23381161

Lee A, Nestaas E, Liestøl K, Brunvand L, Lindemann R, Fugelseth D (2013)
Tissue Doppler imaging in very preterm infants during the first 24 h of life: an observational study
Arch Dis Child Fetal Neonatal Ed, 99 (1), F64-9
PubMed 24048254

Publications 2012

Nestaas E, Støylen A, Fugelseth D (2012)
Myocardial performance assessment in neonates by one-segment strain and strain rate analysis by tissue Doppler - a quality improvement cohort study
BMJ Open, 2 (4)
PubMed 22923633

Publications 2011

Fugelseth D, Ramstad HB, Kvehaugen AS, Nestaas E, Støylen A, Staff AC (2011)
Myocardial function in offspring 5-8years after pregnancy complicated by preeclampsia
Early Hum Dev, 87 (8), 531-5
PubMed 21550734

Henrichsen T, Lindenskov PH, Shaffer TH, Loekke RJ, Fugelseth D, Lindemann R (2011)
Perfluorodecalin lavage of a longstanding lung atelectasis in a child with spinal muscle atrophy
Pediatr Pulmonol, 47 (4), 415-9
PubMed 22006656

Kvehaugen AS, Dechend R, Ramstad HB, Troisi R, Fugelseth D, Staff AC (2011)
Endothelial function and circulating biomarkers are disturbed in women and children after preeclampsia
Hypertension, 58 (1), 63-9
PubMed 21606387

Publications 2010

Bakkeheim E, Bergerud U, Schmidt-Melbye AC, Akkok CA, Liestol K, Fugelseth D, Lindemann R (2010)
Maternal IgG Anti-A and Anti-B Titres Predict Outcome in ABO-Incompatibility in the Neonate EDITORIAL COMMENT
Obstet. Gynecol. Surv., 65 (3), 160-162

Nestaas E, Støylen A, Brunvand L, Fugelseth D (2010)
Longitudinal strain and strain rate by tissue Doppler are more sensitive indices than fractional shortening for assessing the reduced myocardial function in asphyxiated neonates
Cardiol Young, 21 (1), 1-7
PubMed 20923594

Publications 2009

Bakkeheim E, Bergerud U, Schmidt-Melbye AC, Akkök CA, Liestøl K, Fugelseth D, Lindemann R (2009)
Maternal IgG anti-A and anti-B titres predict outcome in ABO-incompatibility in the neonate
Acta Paediatr, 98 (12), 1896-901
PubMed 19703120

Lee A, Liestøl K, Nestaas E, Brunvand L, Lindemann R, Fugelseth D (2009)
Superior vena cava flow: feasibility and reliability of the off-line analyses
Arch Dis Child Fetal Neonatal Ed, 95 (2), F121-5
PubMed 19996328

Nestaas E, Støylen A, Brunvand L, Fugelseth D (2009)
Tissue Doppler derived longitudinal strain and strain rate during the first 3 days of life in healthy term neonates
Pediatr Res, 65 (3), 357-62
PubMed 19391252

Publications 2008

Fredly S, Aksnes G, Viddal KO, Lindemann R, Fugelseth D (2008)
The outcome in newborns with congenital diaphragmatic hernia in a Norwegian region
Acta Paediatr, 98 (1), 107-11
PubMed 18795908

Lindemann R, Myhre MC, Bakken M, Fugelseth D, Rustad CF, Woldseth B (2008)
[A newborn infant with hyperventilation]
Tidsskr Nor Laegeforen, 128 (13), 1535-6
PubMed 18604903

Nestaas E, Støylen A, Fugelseth D (2008)
Optimal types of probe, and tissue Doppler frame rates, for use during tissue Doppler recording and off-line analysis of strain and strain rate in neonates at term
Cardiol Young, 18 (5), 502-11
PubMed 18752713

Publications 2007

Lindemann R, Rajka T, Henrichsen T, Vinorum OG, de Lange C, Erichsen A, Fugelseth D (2007)
Bronchioalveolar lavage with perfluorochemical liquid during conventional ventilation
Pediatr Crit Care Med, 8 (5), 486-8
PubMed 17693917

Nestaas E, Stoylen A, Sandvik L, Brunvand L, Fugelseth D (2007)
Feasibility and reliability of strain and strain rate measurement in neonates by optimizing the analysis parameters settings
Ultrasound Med Biol, 33 (2), 270-8
PubMed 17207903

Publications 2006

Børke WB, Edvardsen T, Fugelseth D, Lenes K, Ihlen H, Saugstad OD, Thaulow E (2006)
Reduced left ventricular function in hypoxemic newborn pigs: a strain Doppler echocardiographic study
Pediatr Res, 59 (5), 630-5
PubMed 16627872

Publications 2005

Fugelseth D, Børke WB, Lenes K, Matthews I, Saugstad OD, Thaulow E (2005)
Restoration of cardiopulmonary function with 21% versus 100% oxygen after hypoxaemia in newborn pigs
Arch Dis Child Fetal Neonatal Ed, 90 (3), F229-34
PubMed 15846013

Publications 2003

Fugelseth D, Satas S, Steen PA, Thoresen M (2003)
Cardiac output, pulmonary artery pressure, and patent ductus arteriosus during therapeutic cooling after global hypoxia-ischaemia
Arch Dis Child Fetal Neonatal Ed, 88 (3), F223-8
PubMed 12719397

Publications 2002

Fugelseth D (2002)
Antenatal cardiac assessment
Scand Cardiovasc J, 36 (2), 67-8
PubMed 12028865

Publications 2001

Fugelseth D (2001)
[Persistent pulmonary hypertension in newborn infants]
Tidsskr Nor Laegeforen, 121 (26), 3074-8
PubMed 11757443

Fugelseth D (2001)
[Neonatal hypoglycemia]
Tidsskr Nor Laegeforen, 121 (14), 1713-6
PubMed 11446016

Fugelseth D, Guthenberg C, Hagenfeldt L, Liestøl K, Hallerud M, Lindemann R (2001)
Patent ductus venosus does not lead to alimentary galactosaemia in preterm infants
Acta Paediatr, 90 (2), 192-5
PubMed 11236050

Nakstad B, Wolfson MR, Aspelin T, Lindemann R, Shaffer TH, Fugelseth D, Lyberg T (2001)
Perfluorochemical liquids do not stimulate endothelin-1 or nitric oxide production in human blood leukocytes
Biol Neonate, 80 (4), 267-72
PubMed 11641549

Nakstad B, Wolfson MR, Shaffer TH, Kähler H, Lindemann R, Fugelseth D, Lyberg T (2001)
Perfluorochemical liquids modulate cell-mediated inflammatory responses
Crit Care Med, 29 (9), 1731-7
PubMed 11546973

Publications 2000

Fugelseth D, Leach CL, Morin FC, Liestøl K, Wang H, Swartz D, Lindemann R (2000)
Ductus venosus flow velocity in newborn lambs during increased pulmonary artery pressure
Pediatr Res, 47 (6), 767-72
PubMed 10832735

Publications 1999

Fugelseth D, Kiserud T, Liestøl K, Langslet A, Lindemann R (1999)
Ductus venosus blood velocity in persistent pulmonary hypertension of the newborn
Arch Dis Child Fetal Neonatal Ed, 81 (1), F35-9
PubMed 10375360

Fugelseth D, Satas S, Runde M, Hågå P, Thoresen M (1999)
Cardiac function and morphology studied by two-dimensional Doppler echocardiography in unsedated newborn pigs
Exp Physiol, 84 (1), 69-78
PubMed 10081708

Publications 1998

Fugelseth D, Lindemann R, Liestøl K, Kiserud T, Langslet A (1998)
Postnatal closure of ductus venosus in preterm infants < or = 32 weeks. An ultrasonographic study
Early Hum Dev, 53 (2), 163-9
PubMed 10195709

Nafstad P, Fugelseth D, Qvigstad E, Zahlen K, Magnus P, Lindemann R (1998)
Nicotine concentration in the hair of nonsmoking mothers and size of offspring
Am J Public Health, 88 (1), 120-4
PubMed 9584018

Orstavik KH, Bechensteen AG, Fugelseth D, Orderud W (1998)
Sibs with Ritscher-Schinzel (3C) syndrome and anal malformations
Am J Med Genet, 75 (3), 300-3
PubMed 9475602

Publications 1997

Fugelseth D, Lindemann R, Liestøl K, Kiserud T, Langslet A (1997)
Ultrasonographic study of ductus venosus in healthy neonates
Arch Dis Child Fetal Neonatal Ed, 77 (2), F131-4
PubMed 9377136

Publications 1996

Brunvand L, Fugelseth D (1996)
[Bacterial endocarditis in premature children. A complication caused by central venous catheters]
Tidsskr Nor Laegeforen, 116 (11), 1328-30
PubMed 8658414

Heier HE, Fugelseth D, Lindemann R, Qvigstad E (1996)
[Maternal blood group 0 as a risk factor of neonatal hyperbilirubinemia requiring treatment]
Tidsskr Nor Laegeforen, 116 (1), 34-6
PubMed 8553332

Publications 1994

Fugelseth D (1994)
[New principles for mechanical ventilation of neonates and infants. High-frequency ventilation]
Tidsskr Nor Laegeforen, 114 (17), 1955-8
PubMed 8079325

Fugelseth D, Lindemann R (1994)
Patient-triggered ventilation fooled by patency of ductus arteriosus
Acta Paediatr, 83 (12), 1263
PubMed 7734866

Fugelseth D, Lindemann R (1994)
[Perinatal care yesterday, today, tomorrow--which way does the pendulum swing?]
Tidsskr Nor Laegeforen, 114 (1), 57-60
PubMed 8296285

Fugelseth D, Lindemann R, Sande HA, Refsum S, Nordshus T (1994)
Prenatal diagnosis of urinary tract anomalies. The value of two ultrasound examinations
Acta Obstet Gynecol Scand, 73 (4), 290-3
PubMed 8160533