Inger Helene Madhus

Publications published between 1984 and 2009 or in press by Inger Helene Madshus

58 publications found

Publications in press

1. Grandal MV, Grøvdal LM, Henriksen L, Andersen MH, Holst MR, Madshus IH, van Deurs B
   Differential Roles of Grb2 and AP-2 in p38 MAPK- and EGF-Induced EGFR Internalization
   Traffic (in press)
   PubMed 22192528

Publications 2009

1. Hughes JB, Berger C, Rødland MS, Hasmann M, Stang E, Madshus IH (2009)
   Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization
   Mol Cancer Ther, 8 (7), 1885-92
   PubMed 19584234
2. Kazazic M, Bertelsen V, Pedersen KW, Vuong TT, Grandal MV, Rødland MS, Traub LM, Stang E, Madshus IH (2009)
   Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits
   Traffic, 10 (2), 235-45
   PubMed 19054389
3. Madshus IH, Stang E (2009)
   Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking
   J Cell Sci, 122 (Pt 19), 3433-9
   PubMed 19759283
4. Pedersen NM, Breen K, Rødland MS, Haslekås C, Stang E, Madshus IH (2009)
   Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2
   Mol Cancer Res, 7 (2), 275-84
   PubMed 19208749

Publications 2008

1. Grandal MV, Madshus IH (2008)
   Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis
   J Cell Mol Med, 12 (5A), 1527-34
   PubMed 18318691
2. Grøvdal LM, Johannessen LE, Rødland MS, Madshus IH, Stang E (2008)
   Dysregulation of Ack1 inhibits down-regulation of the EGF receptor
   Exp Cell Res, 314 (6), 1292-300
   PubMed 18262180
3. Pedersen NM, Madshus IH, Haslekås C, Stang E (2008)
   Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent
   Mol Cancer Res, 6 (3), 491-500
   PubMed 18337455

Publications 2007

1. Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
   The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
   Exp Cell Res, 313 (8), 1696-709
   PubMed 17382318

Publications 2006

1. Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
   Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
   Mol Cell Biol, 26 (2), 389-401
   PubMed 16382132
2. Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
   EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
   Traffic, 7 (11), 1518-27
   PubMed 16984407
3. Madshus IH (2006)
   Ubiquitin binding in endocytosis--how tight should it be and where does it happen?
   Traffic, 7 (3), 258-61
   PubMed 16497221
4. Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
   Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
   Exp Cell Res, 312 (16), 3036-48
   PubMed 16859684

Publications 2005

1. Haslekås C, Breen K, Pedersen KW, Johannessen LE, Stang E, Madshus IH (2005)
   The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane
   Mol Biol Cell, 16 (12), 5832-42
   PubMed 16207817
2. Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
   Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
   Int J Cancer, 116 (3), 359-67
   PubMed 15800944

Publications 2004

1. Grøvdal LM, Stang E, Sorkin A, Madshus IH (2004)
   Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation
   Exp Cell Res, 300 (2), 388-95
   PubMed 15475003
2. Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
   Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
   Mol Biol Cell, 15 (8), 3591-604
   PubMed 15194809

Publications 2003

1. Normann AP, Egeland T, Madshus IH, Heim S, Tjønnfjord GE (2003)
   CD7 expression by CD34+ cells in CML patients, of prognostic significance?
   Eur J Haematol, 71 (4), 266-75
   PubMed 12950236

Publications 2002

1. Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
   Phosphorylation of Hrs downstream of the epidermal growth factor receptor
   Eur J Biochem, 269 (16), 3881-7
   PubMed 12180964
2. Longva KE, Blystad FD, Stang E, Larsen AM, Johannessen LE, Madshus IH (2002)
   Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies
   J Cell Biol, 156 (5), 843-54
   PubMed 11864992
3. Oksvold M, Huitfeldt H, Stang E, Madshus I (2002)
   Localizing the EGF receptor
   Nat Cell Biol, 4 (2), E22; author reply E22-3
   PubMed 11835048
4. Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
   Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
   Nat Cell Biol, 4 (5), 394-8
   PubMed 11988743
5. Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E (2002)
   Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae
   J Cell Sci, 115 (Pt 6), 1331-40
   PubMed 11884532

Publications 2001

1. Johannessen LE, Haugen KE, østvold AC, Stang E, Madshus IH (2001)
   Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms
   Biochem J, 356 (Pt 1), 87-96
   PubMed 11336639

Publications 2000

1. Johannessen LE, Ringerike T, Molnes J, Madshus IH (2000)
   Epidermal growth factor receptor efficiently activates mitogen-activated protein kinase in HeLa cells and Hep2 cells conditionally defective in clathrin-dependent endocytosis
   Exp Cell Res, 260 (1), 136-45
   PubMed 11010818
2. Stang E, Johannessen LE, Knardal SL, Madshus IH (2000)
   Polyubiquitination of the epidermal growth factor receptor occurs at the plasma membrane upon ligand-induced activation
   J Biol Chem, 275 (18), 13940-7
   PubMed 10788520

Publications 1999

1. Johannessen LE, Knardal SL, Madshus IH (1999)
   Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein
   Biochem J, 337 ( Pt 3), 599-606
   PubMed 9895307
2. Lindeman B, Skarpen E, Thoresen GH, Christoffersen T, Wierød L, Madshus IH, Huitfeldt HS (1999)
   Alteration of G1 cell-cycle protein expression and induction of p53 but not p21/waf1 by the DNA-modifying carcinogen 2-acetylaminofluorene in growth-stimulated hepatocytes in vitro
   Mol Carcinog, 24 (1), 36-46
   PubMed 10029409

Publications 1998

1. Nogva HK, Evensen SA, Madshus IH (1998)
   One-tube multiplex RT-PCR of BCR-ABL transcripts in analysis of patients with chronic myeloid leukaemia and acute lymphoblastic leukaemia
   Scand J Clin Lab Invest, 58 (8), 647-54
   PubMed 10088201
2. Ringerike T, Stang E, Johannessen LE, Sandnes D, Levy FO, Madshus IH (1998)
   High-affinity binding of epidermal growth factor (EGF) to EGF receptor is disrupted by overexpression of mutant dynamin (K44A)
   J Biol Chem, 273 (27), 16639-42
   PubMed 9642213
3. Skarpen E, Johannessen LE, Bjerk K, Fasteng H, Guren TK, Lindeman B, Thoresen GH, Christoffersen T, Stang E, Huitfeldt HS, Madshus IH (1998)
   Endocytosed epidermal growth factor (EGF) receptors contribute to the EGF-mediated growth arrest in A431 cells by inducing a sustained increase in p21/CIP1
   Exp Cell Res, 243 (1), 161-72
   PubMed 9716460

Publications 1995

1. Madshus IH (1995)
   Diphtheria toxin can be used as a vehicle for bringing other proteins into cells
   Restor Neurol Neurosci, 8 (1), 13-4
   PubMed 21551798

Publications 1994

1. Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S (1994)
   Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
   J Biol Chem, 269 (11), 8402-7
   PubMed 8132565
2. Madshus IH (1994)
   The N-terminal alpha-helix of fragment B of diphtheria toxin promotes translocation of fragment A into the cytoplasm of eukaryotic cells
   J Biol Chem, 269 (26), 17723-9
   PubMed 8021285
3. Madshus IH, Wiedlocha A, Sandvig K (1994)
   Intermediates in translocation of diphtheria toxin across the plasma membrane
   J Biol Chem, 269 (6), 4648-52
   PubMed 7508447
4. Wied?ocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
   Dual mode of signal transduction by externally added acidic fibroblast growth factor
   Cell, 76 (6), 1039-51
   PubMed 7511061

Publications 1993

1. Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
   Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
   Biochemistry, 32 (1), 83-90
   PubMed 8418864
2. Esbensen QY, Falnes PO, Olsnes S, Madshus IH (1993)
   Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
   Biochem J, 294 ( Pt 3), 663-6
   PubMed 8379922

Publications 1992

1. Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
   Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
   J Biol Chem, 267 (17), 12284-90
   PubMed 1376320
2. Madshus IH, Olsnes S, Stenmark H (1992)
   Membrane translocation of diphtheria toxin carrying passenger protein domains
   Infect Immun, 60 (8), 3296-302
   PubMed 1639497
3. Madshus IH, Stenmark H (1992)
   Entry of ADP-ribosylating toxins into cells
   Curr Top Microbiol Immunol, 175, 1-26
   PubMed 1378368
4. Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
   Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
   EMBO J, 11 (13), 4835-42
   PubMed 1281450

Publications 1991

1. Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
   Entry of diphtheria toxin-protein A chimeras into cells
   J Biol Chem, 266 (26), 17446-53
   PubMed 1894632
2. Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
   Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
   J Cell Biol, 113 (5), 1025-32
   PubMed 2040642
3. Stenmark H, Olsnes S, Madshus IH (1991)
   Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
   Mol Microbiol, 5 (3), 595-606
   PubMed 1646374

Publications 1990

1. Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
   Protein toxins with intracellular targets
   Microb Pathog, 8 (3), 163-8
   PubMed 1696341

Publications 1989

1. Madshus IH, Collier RJ (1989)
   Effects of eliminating a disulfide bridge within domain II of Pseudomonas aeruginosa exotoxin A
   Infect Immun, 57 (7), 1873-8
   PubMed 2499539

Publications 1988

1. Madshus IH (1988)
   Regulation of intracellular pH in eukaryotic cells
   Biochem J, 250 (1), 1-8
   PubMed 2965576

Publications 1987

1. Madshus IH, Olsnes S (1987)
   Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
   J Biol Chem, 262 (16), 7486-91
   PubMed 3584123
2. Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
   Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
   J Cell Physiol, 131 (1), 14-22
   PubMed 3032992
3. Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
   Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
   J Cell Physiol, 131 (1), 6-13
   PubMed 3571337
4. Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
   Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
   Exp Cell Res, 170 (2), 483-90
   PubMed 3036553

Publications 1985

1. Madshus IH, Sandvig K, Olsnes S (1985)
   Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
   Exp Cell Res, 160 (1), 240-4
   PubMed 2995095
2. Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
   Entry mechanisms of protein toxins and picornaviruses
   Biochem Soc Symp, 50, 171-91
   PubMed 3915869

Publications 1984

1. Madshus IH, Olsnes S, Sandvig K (1984)
   Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
   J Cell Biol, 98 (4), 1194-200
   PubMed 6325467
2. Madshus IH, Olsnes S, Sandvig K (1984)
   Requirements for entry of poliovirus RNA into cells at low pH
   EMBO J, 3 (9), 1945-50
   PubMed 6092049
3. Madshus IH, Olsnes S, Sandvig K (1984)
   Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
   Virology, 139 (2), 346-57
   PubMed 6097029
4. Sandvig K, Madshus IH, Olsnes S (1984)
   Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
   Biochem J, 219 (3), 935-40
   PubMed 6331401