Lina Cekaite
Position: Senior scientist, Dr.philos
Phone: +47 2278 1730
Email:
Lina is a senior scientist in the Molecular Genetics Group and her primary interest is translational research relevant for colorectal cancer. She has been recipient of a 4-year Researcher Fellowship for the project "MiRNAs in Colorectal Cancer: Their Functional and Clinical Impact" by South-Eastern Norway Regional Health Authority (Helse Sør-Øst) research grant funds.

Ongoing tasks
-Member of the CCB – Center for Cancer Biomedicine Seminar Committee and taking part in organizing CCB seminars.
-Member of the TEKNA Biotek (The Panel of TEKNA members who are interested in or working on issues related to biotechnology) Oslo Committee, organizing TEKNA Biotek seminars in Oslo and Ås.

Academic degrees
PhD. (2007) University of Oslo, Faculty of medicine. PhD thesis, entitled “Microarrays on Macromolecules: Implication of high throughput methods in cancer screening”. PhD supervisor Prof. Eivind Hovig, Dept. of Tumor Biology, Institute for Cancer research.
M.Sc. (2001) Vilnius University, Faculty of Natural Science. MSc thesis: ‘Vaccination of Atlantic salmon (Salmo salar L): Effect of different adjuvants on immune response against Infectious Pancreas Necrosis Virus (IPNV)’. The MSc. Thesis was supervised by Anne Aas-Eng at Aquatic Health Division, Alpharma AS (later taken over by Pharmaq), Oslo.
 

Author network for Lina Cekaite by COREMINE medical


Publications 2013

Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E (2013)
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
Cell Signal, 25 (1), 12-8
PubMed 22974840

Publications 2012

Cekaite L, Rantala JK, Bruun J, Guriby M, Agesen TH, Danielsen SA, Lind GE, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2012)
MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
Neoplasia, 14 (9), 868-79
PubMed 23019418

Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, Canamero M, Bujanda L, Schedl A, Cheah KS, Skotheim RI, Lothe RA, López de Munain A, Briscoe J, Serrano M, Lovell-Badge R (2012)
Oncogenicity of the developmental transcription factor Sox9
Cancer Res, 72 (5), 1301-15
PubMed 22246670

Publications 2011

Danielsen SA, Cekaite L, Ågesen TH, Sveen A, Nesbakken A, Thiis-Evensen E, Skotheim RI, Lind GE, Lothe RA (2011)
Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
PLoS One, 6 (9), e24419
PubMed 21909432

Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
Genes Immun, 12 (8), 653-62
PubMed 21716316

Publications 2010

Cekaite L, Clancy T, Sioud M (2010)
Increased miR-21 expression during human monocyte differentiation into DCs
Front Biosci (Elite Ed), 2, 818-28
PubMed 20515755

Sioud M, Cekaite L (2010)
Profiling of miRNA expression and prediction of target genes
Methods Mol Biol, 629, 257-71
PubMed 20387154

Publications 2009

Cekaite L, Hovig E, Sioud M (2009)
Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
Methods Mol Biol, 524, 273-85
PubMed 19377952

Sioud M, Boudabous A, Cekaite L (2009)
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
Int J Mol Med, 23 (1), 33-9
PubMed 19082504

Publications 2008

Sioud M, Cekaite L (2008)
Expression profiling of microRNAs in cancer cells: technical considerations
Methods Mol Biol, 439, 179-90
PubMed 18370103

Publications 2007

Cekaite L, Furset G, Hovig E, Sioud M (2007)
Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
J Mol Biol, 365 (1), 90-108
PubMed 17054988

Cekaite L, Hovig E, Sioud M (2007)
Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
Methods Mol Biol, 360, 335-48
PubMed 17172738

Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
BMC Genomics, 8, 273
PubMed 17692132

Sioud M, Furset G, Cekaite L (2007)
Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
Biochem Biophys Res Commun, 361 (1), 122-6
PubMed 17658482

Publications 2006

Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
FEBS Lett, 580 (24), 5739-46
PubMed 17007842

Publications 2004

Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
PubMed 15352232

Cekaite L, Hovig E, Hauge HH (2004)
Double-sided silicon strip detectors: new applications within genomics and proteomics
Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72