Ragnhild A. Lothe's group

Publications from OUS - Molecular Cancer Genetics

197 publications found

Publications in press

1. Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA
   ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
   Gut (in press)
   PubMed 22213796
2. Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, Canamero M, Bujanda L, Schedl A, Cheah KS, Skotheim RI, Lothe RA, Lopez de Munain A, Briscoe J, Serrano M, Lovell-Badge R
   Oncogenicity of the developmental transcription factor Sox9
   Cancer Res (in press)
   PubMed 22246670
3. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E
   Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
   Int J Cancer (in press)
   PubMed 21866551
4. Sveen A, Bakken AC, Agesen TH, Lind GE, Nesbakken A, Nordgård O, Brackmann S, Rognum TO, Lothe RA, Skotheim RI
   The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
   Int J Cancer (in press)
   PubMed 22173985

Publications 2012

1. Paulo P, Barros-Silva JD, Ribeiro FR, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2012)
   FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer
   Genes Chromosomes Cancer, 51 (3), 240-9
   PubMed 22081504

Publications 2011

1. Ahmed D, Lothe RA, Rivedal E, Lind GE (2011)
   Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors
   Endocr Relat Cancer, 18 (6), C31-4
   PubMed 21868474
2. Alagaratnam S, Lind GE, Kraggerud SM, Lothe RA, Skotheim RI (2011)
   The testicular germ cell tumour transcriptome
   Int J Androl, 34 (4 Pt 2), e133-50; discussion e150-1
   PubMed 21651573
3. Berge G, Costea DE, Berg M, Rasmussen H, Grotterød I, Lothe RA, Mælandsmo GM, Flatmark K (2011)
   Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
   Amino Acids, 41 (4), 875-84
   PubMed 20191297
4. Boberg KM, Lind GE (2011)
   Primary sclerosing cholangitis and malignancy
   Best Pract Res Clin Gastroenterol, 25 (6), 753-64
   PubMed 22117640
5. Costa VL, Henrique R, Danielsen SA, Eknaes M, Patrício P, Morais A, Oliveira J, Lothe RA, Teixeira MR, Lind GE, Jerónimo C (2011)
   TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers
   Epigenetics, 6 (9), 1120-1130
   PubMed 21847011
6. Danielsen SA, Cekaite L, Ågesen TH, Sveen A, Nesbakken A, Thiis-Evensen E, Skotheim RI, Lind GE, Lothe RA (2011)
   Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
   PLoS One, 6 (9), e24419
   PubMed 21909432
7. Lind GE, Danielsen SA, Ahlquist T, Merok MA, Andresen K, Skotheim RI, Hektoen M, Rognum TO, Meling GI, Hoff G, Bretthauer M, Thiis-Evensen E, Nesbakken A, Lothe RA (2011)
   Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
   Mol Cancer, 10, 85
   PubMed 21777459
8. Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
   SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
   Oncogene, 30 (37), 3967-78
   PubMed 21499309
9. Løvf M, Thomassen GO, Bakken AC, Celestino R, Fioretos T, Lind GE, Lothe RA, Skotheim RI (2011)
   Fusion gene microarray reveals cancer type-specificity among fusion genes
   Genes Chromosomes Cancer, 50 (5), 348-57
   PubMed 21305644
10. Ohnstad HO, Paulsen EB, Noordhuis P, Berg M, Lothe RA, Vassilev LT, Myklebost O (2011)
    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
    BMC Cancer, 11, 211:1-11
    PubMed 21624110
11. Ribeiro FR, Paulo P, Costa VL, Barros-Silva JD, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2011)
    Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene
    PLoS One, 6 (7), e22317
    PubMed 21814574
12. Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
    A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
    PLoS One, 6 (3), e17086
    PubMed 21455500
13. Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE (2011)
    DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
    Epigenetics, 6 (5), 602-9
    PubMed 21406965
14. Sjo OH, Berg M, Merok MA, Kolberg M, Svindland A, Lothe RA, Nesbakken A (2011)
    Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
    J Surg Oncol, 104 (7), 792-7
    PubMed 21547915
15. Soreide K, Berg M, Skudal BS, Nedreboe BS (2011)
    Advances in the understanding and treatment of colorectal cancer
    Discov Med, 12 (66), 393-404
    PubMed 22127110
16. Sveen A, Agesen TH, Nesbakken A, Rognum TO, Lothe RA, Skotheim RI (2011)
    Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
    Genome Med, 3 (5), 32
    PubMed 21619627
17. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    PubMed 21716316

Publications 2010

1. Berg M, Agesen TH, Thiis-Evensen E, INFAC-study group, Merok MA, Teixeira MR, Vatn MH, Nesbakken A, Skotheim RI, Lothe RA (2010)
   Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
   Mol Cancer, 9, 100
   PubMed 20459617
2. Berg M, Danielsen SA, Ahlquist T, Merok MA, Ågesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen Ø, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA (2010)
   DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
   PLoS One, 5 (11), e13978
   PubMed 21103049
3. Brekke HR, Ribeiro FR, Kolberg M, Agesen TH, Lind GE, Eknaes M, Hall KS, Bjerkehagen B, van den Berg E, Teixeira MR, Mandahl N, Smeland S, Mertens F, Skotheim RI, Lothe RA (2010)
   Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group
   J Clin Oncol, 28 (9), 1573-82
   PubMed 20159821
4. Burum-Auensen E, Skotheim RI, Schjølberg AR, Røislien J, Lothe RA, Clausen OP (2010)
   Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
   J Carcinog, 9, 1
   PubMed 20411023
5. Cekaite L, Clancy T, Sioud M (2010)
   Increased miR-21 expression during human monocyte differentiation into DCs
   Front Biosci (Elite Ed), 2, 818-28
   PubMed 20515755
6. Costa VL, Henrique R, Danielsen SA, Duarte-Pereira S, Eknaes M, Skotheim RI, Rodrigues A, Magalhães JS, Oliveira J, Lothe RA, Teixeira MR, Jerónimo C, Lind GE (2010)
   Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples
   Clin Cancer Res, 16 (23), 5842-51
   PubMed 20975101
7. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
   UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
   Autophagy, 6 (7), 863-70
   PubMed 20724836
8. Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E (2010)
   Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
   Toxicol Appl Pharmacol, 247 (1), 10-7
   PubMed 20510257
9. Micci F, Haugom L, Ahlquist T, Andersen HK, Abeler VM, Davidson B, Trope CG, Lothe RA, Heim S (2010)
   Genomic aberrations in borderline ovarian tumors
   J Transl Med, 8, 21
   PubMed 20184781
10. Micci F, Skotheim RI, Haugom L, Weimer J, Eibak AM, Abeler VM, Trope CG, Arnold N, Lothe RA, Heim S (2010)
    Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
    Genes Chromosomes Cancer, 49 (11), 1046-53
    PubMed 20725991
11. Pinheiro M, Ahlquist T, Danielsen SA, Lind GE, Veiga I, Pinto C, Costa V, Afonso L, Sousa O, Fragoso M, Santos L, Henrique R, Lopes P, Lopes C, Lothe RA, Teixeira MR (2010)
    Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin
    BMC Cancer, 10, 587
    PubMed 20979647
12. Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
    PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Nat Cell Biol, 12 (4), 362-71
    PubMed 20208530
13. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    PubMed 20387154
14. Zwierzina H, Bardelli A, Ciardiello F, Gariboldi M, Håkansson L, Lambrechts D, Lind GE, Loeffler-Ragg J, Schmoll H, Siena S, Tabernero J, Van Cutsem E (2010)
    Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials
    Curr Opin Mol Ther, 12 (6), 703-11
    PubMed 21154162

Publications 2009

1. Ahlquist T (2009)
   New doctorial cancer research:novel genetic and epigenetic alterations in colorectal tumors and their potential as biomarkers
   Crit Rev Oncog, 15 (1), 81-3
   PubMed 20092436
2. Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, Byrne JA (2009)
   TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours
   Mol Cell Endocrinol, 306 (1-2), 75-80
   PubMed 19041365
3. Bottillo I, Ahlquist T, Brekke H, Danielsen SA, van den Berg E, Mertens F, Lothe RA, Dallapiccola B (2009)
   Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours
   J Pathol, 217 (5), 693-701
   PubMed 19142971
4. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
   Autophagy in tumour suppression and promotion
   Mol Oncol, 3 (4), 366-75
   PubMed 19559660
5. Brekke HR, Kolberg M, Skotheim RI, Hall KS, Bjerkehagen B, Risberg B, Domanski HA, Mandahl N, Liestøl K, Smeland S, Danielsen HE, Mertens F, Lothe RA (2009)
   Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
   Neuro Oncol, 11 (5), 514-28
   PubMed 19182148
6. Cekaite L, Hovig E, Sioud M (2009)
   Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
   Methods Mol Biol, 524, 273-85
   PubMed 19377952
7. Danielsen SA, Lind GE, Biornslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2009)
   Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
   Hum. Mutat., 30 (6), 1023
8. Godmann M, Gashaw I, Eildermann K, Schweyer S, Bergmann M, Skotheim RI, Behr R (2009)
   The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma
   Mol Hum Reprod, 15 (8), 479-88
   PubMed 19505997
9. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
   Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
   Pharmacogenet Genomics, 19 (10), 751-9
   PubMed 19741569
10. Micci F, Haugom L, Ahlquist T, Abeler VM, Trope CG, Lothe RA, Heim S (2009)
    Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
    J Oncol, 2010, 646340
    PubMed 19759843
11. Micci F, Weimer J, Haugom L, Skotheim RI, Grunewald R, Abeler VM, Silins I, Lothe RA, Trope CG, Arnold N, Heim S (2009)
    Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
    Genes Chromosomes Cancer, 48 (2), 184-93
    PubMed 18973136
12. Nilsen H, Olsen HG, Hayes B, Sehested E, Svendsen M, Nome T, Meuwissen T, Lien S (2009)
    Casein haplotypes and their association with milk production traits in Norwegian Red cattle
    Genet Sel Evol, 41, 24
    PubMed 19284706
13. Pretorius ME, Waehre H, Abeler VM, Davidson B, Vlatkovic L, Lothe RA, Giercksky KE, Danielsen HE (2009)
    Large scale genomic instability as an additive prognostic marker in early prostate cancer
    Cell Oncol, 31 (4), 251-9
    PubMed 19633362
14. Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA (2009)
    A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
    Mol Cancer, 8, 5
    PubMed 19152679

Publications 2008

1. Ahlquist T, Bottillo I, Danielsen SA, Meling GI, Rognum TO, Lind GE, Dallapiccola B, Lothe RA (2008)
   RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
   Neoplasia, 10 (7), 680-6, 2 p following 686
   PubMed 18592002
2. Ahlquist T, Lind GE, Costa VL, Meling GI, Vatn M, Hoff GS, Rognum TO, Skotheim RI, Thiis-Evensen E, Lothe RA (2008)
   Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
   Mol Cancer, 7, 94
   PubMed 19117505
3. Danielsen SA, Lind GE, Bjørnslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2008)
   Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
   Hum Mutat, 29 (11), E252-62
   PubMed 18781614
4. Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa-Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O (2008)
   Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues
   Genome Biol, 9 (9), R139
   PubMed 18803840
5. Lind GE, Ahlquist T, Kolberg M, Berg M, Eknaes M, Alonso MA, Kallioniemi A, Meling GI, Skotheim RI, Rognum TO, Thiis-Evensen E, Lothe RA (2008)
   Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
   J Transl Med, 6, 13
   PubMed 18346269
6. Sioud M, Cekaite L (2008)
   Expression profiling of microRNAs in cancer cells: technical considerations
   Methods Mol Biol, 439, 179-90
   PubMed 18370103

Publications 2007

1. Almstrup K, Leffers H, Lothe RA, Skakkebaek NE, Sonne SB, Nielsen JE, Rajpert-De Meyts E, Skotheim RI (2007)
   Improved gene expression signature of testicular carcinoma in situ
   Int J Androl, 30 (4), 292-302; discussion 303
   PubMed 17488342
2. Cekaite L, Furset G, Hovig E, Sioud M (2007)
   Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
   J Mol Biol, 365 (1), 90-108
   PubMed 17054988
3. Cekaite L, Hovig E, Sioud M (2007)
   Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
   Methods Mol Biol, 360, 335-48
   PubMed 17172738
4. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
   Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
   BMC Genomics, 8, 273
   PubMed 17692132
5. Hoei-Hansen CE, Kraggerud SM, Abeler VM, Kaern J, Rajpert-De Meyts E, Lothe RA (2007)
   Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
   Mol Cancer, 6, 12
   PubMed 17274819
6. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
   Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
   Mol Cancer, 6, 2
   PubMed 17201907
7. Lind GE, Ahlquist T, Lothe RA (2007)
   DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors
   Gastroenterology, 132 (4), 1631-2; author reply 1632
   PubMed 17408629
8. Lind GE, Skotheim RI, Lothe RA (2007)
   The epigenome of testicular germ cell tumors
   APMIS, 115 (10), 1147-60
   PubMed 18042148
9. Oldenburg J, Kraggerud SM, Brydøy M, Cvancarova M, Lothe RA, Fossa SD (2007)
   Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
   J Transl Med, 5, 70
   PubMed 18162130
10. Oldenburg J, Kraggerud SM, Cvancarova M, Lothe RA, Fossa SD (2007)
    Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors
    J Clin Oncol, 25 (6), 708-14
    PubMed 17228018
11. Røyrvik EC, Ahlquist T, Rognes T, Lothe RA (2007)
    Slip slidin' away: a duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
    Crit Rev Oncog, 13 (3), 229-57
    PubMed 18298386
12. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    PubMed 17658482
13. Skotheim RI, Nees M (2007)
    Alternative splicing in cancer: noise, functional, or systematic?
    Int J Biochem Cell Biol, 39 (7-8), 1432-49
    PubMed 17416541
14. Wu Q, Lind GE, Aasheim HC, Micci F, Silins I, Tropé CG, Nesland JM, Lothe RA, Suo Z (2007)
    The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers
    Epigenetics, 2 (4), 237-43
    PubMed 18281782
15. Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE (2007)
    DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
    Mol Cancer, 6, 45
    PubMed 17623056

Publications 2006

1. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2006)
   The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
   Genes Chromosomes Cancer, 45 (1), 31-41
   PubMed 16145679
2. Iacopetta B, Russo A, Bazan V, Dardanoni G, Gebbia N, Soussi T, Kerr D, Elsaleh H, Soong R, Kandioler D, Janschek E, Kappel S, Lung M, Leung CS, Ko JM, Yuen S, Ho J, Leung SY, Crapez E, Duffour J, Ychou M, Leahy DT, O'Donoghue DP, Agnese V, Cascio S et al. (2006)
   Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
   Ann Oncol, 17 (5), 842-7
   PubMed 16524972
3. Iljin K, Wolf M, Edgren H, Gupta S, Kilpinen S, Skotheim RI, Peltola M, Smit F, Verhaegh G, Schalken J, Nees M, Kallioniemi O (2006)
   TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
   Cancer Res, 66 (21), 10242-6
   PubMed 17079440
4. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
   ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
   Cell Oncol, 28 (5-6), 259-72
   PubMed 17167179
5. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Esteller M, Lothe RA (2006)
   Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
   J Pathol, 210 (4), 441-9
   PubMed 17029216
6. Lothe RA, Skotheim RI, Kallioniemi O, Esteller M (2006)
   To the Readers and Future Authors of Critical Reviews in Oncogenesis
   Critical Reviews in Oncogenesis, 12 (1-2), 1-2
   PublikaID 27
7. Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
   Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
   FEBS Lett, 580 (24), 5739-46
   PubMed 17007842
8. Ribeiro FR, Diep CB, Jerónimo C, Henrique R, Lopes C, Eknaes M, Lingjaerde OC, Lothe RA, Teixeira MR (2006)
   Statistical dissection of genetic pathways involved in prostate carcinogenesis
   Genes Chromosomes Cancer, 45 (2), 154-63
   PubMed 16235241
9. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
   Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
   Mol Cancer, 5, 33
   PubMed 16952311
10. Ribeiro FR, Jerónimo C, Henrique R, Fonseca D, Oliveira J, Lothe RA, Teixeira MR (2006)
    8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects
    Clin Cancer Res, 12 (13), 3961-70
    PubMed 16818693
11. Skotheim RI, Autio R, Lind GE, Kraggerud SM, Andrews PW, Monni O, Kallioniemi O, Lothe RA (2006)
    Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes
    Cell Oncol, 28 (5-6), 315-26
    PubMed 17167184
12. Storlazzi CT, Brekke HR, Mandahl N, Brosjö O, Smeland S, Lothe RA, Mertens F (2006)
    Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    J Pathol, 209 (4), 492-500
    PubMed 16721726
13. von Eyben FE, Jacobsen GK, Skotheim RI, von der Maase H, Rorth M (2006)
    Precursor lesions in testis and dysgenetic gonads
    Hum Pathol, 37 (6), 773; author reply 774
    PubMed 16733221

Publications 2005

1. Agesen TH, Flørenes VA, Molenaar WM, Lind GE, Berner JM, Plaat BE, Komdeur R, Myklebost O, van den Berg E, Lothe RA (2005)
   Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
   J Neuropathol Exp Neurol, 64 (1), 74-81
   PubMed 15715087
2. Castro P, Eknaes M, Teixeira MR, Danielsen HE, Soares P, Lothe RA, Sobrinho-Simões M (2005)
   Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
   J Pathol, 206 (3), 305-11
   PubMed 15852498
3. Hofer MD, Browne TJ, He L, Skotheim RI, Lothe RA, Rubin MA (2005)
   Identification of two molecular groups of seminomas by using expression and tissue microarrays
   Clin Cancer Res, 11 (16), 5722-9
   PubMed 16115909
4. Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2005)
   TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
   J Pathol, 207 (1), 14-9
   PubMed 16007576
5. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Henrique R, Saatcioglu F, Esteller M, Teixeira MR, Lothe RA (2005)
   The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation
   Mol Cancer, 4 (1), 8
   PubMed 15691383
6. Skotheim RI, Lind GE, Monni O, Nesland JM, Abeler VM, Fosså SD, Duale N, Brunborg G, Kallioniemi O, Andrews PW, Lothe RA (2005)
   Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development
   Cancer Res, 65 (13), 5588-98
   PubMed 15994931
7. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
   Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
   Methods Mol Biol, 291, 207-16
   PubMed 15502225
8. Thorstensen L, Lind GE, Løvig T, Diep CB, Meling GI, Rognum TO, Lothe RA (2005)
   Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
   Neoplasia, 7 (2), 99-108
   PubMed 15802015
9. von Eyben FE, Jacobsen GK, Skotheim RI (2005)
   Microinvasive germ cell tumor of the testis
   Virchows Arch, 447 (3), 610-25
   PubMed 15968545

Publications 2004

1. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
   Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
   Proteomics, 4 (9), 2572-82
   PubMed 15352232
2. Cekaite L, Hovig E, Hauge HH (2004)
   Double-sided silicon strip detectors: new applications within genomics and proteomics
   Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72
3. Diep CB, Teixeira MR, Thorstensen L, Wiig JN, Eknaes M, Nesland JM, Giercksky KE, Johansson B, Lothe RA (2004)
   Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients
   Mol Cancer, 3, 6
   PubMed 14977426
4. Kildal W, Kaern J, Kraggerud SM, Abeler VM, Sudbø J, Tropè CG, Lothe RA, Danielsen HE (2004)
   Evaluation of genomic changes in a large series of malignant ovarian germ cell tumors--relation to clinicopathologic variables
   Cancer Genet Cytogenet, 155 (1), 25-32
   PubMed 15527899
5. Kleivi K, Teixeira MR, Eknaes M, Diep CB, Jakobsen KS, Hamelin R, Lothe RA (2004)
   Genome signatures of colon carcinoma cell lines
   Cancer Genet Cytogenet, 155 (2), 119-31
   PubMed 15571797
6. Lind GE, Thorstensen L, Løvig T, Meling GI, Hamelin R, Rognum TO, Esteller M, Lothe RA (2004)
   A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
   Mol Cancer, 3, 28
   PubMed 15476557
7. Richard SM, Bianchi NO, Bianchi MS, Peltomäki P, Lothe RA, Pavicic W (2004)
   Ethnic variation in the prevalence of AZF deletions in testicular cancer
   Mutat Res, 554 (1-2), 45-51
   PubMed 15450403
8. Teixeira MR, Ribeiro FR, Eknaes M, Waehre H, Stenwig AE, Giercksky KE, Heim S, Lothe RA (2004)
   Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making
   Cancer, 101 (8), 1786-93
   PubMed 15386312
9. Teixeira MR, Ribeiro FR, Torres L, Pandis N, Andersen JA, Lothe RA, Heim S (2004)
   Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis
   Br J Cancer, 91 (4), 775-82
   PubMed 15266323

Publications 2003

1. Brandal P, Micci F, Bjerkehagen B, Eknaes M, Larramendy M, Lothe RA, Knuutila S, Heim S (2003)
   Molecular cytogenetic characterization of desmoid tumors
   Cancer Genet Cytogenet, 146 (1), 1-7
   PubMed 14499689
2. Diep CB, Parada LA, Teixeira MR, Eknaes M, Nesland JM, Johansson B, Lothe RA (2003)
   Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis
   Genes Chromosomes Cancer, 36 (2), 189-97
   PubMed 12508247
3. Diep CB, Thorstensen L, Meling GI, Skovlund E, Rognum TO, Lothe RA (2003)
   Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients
   J Clin Oncol, 21 (5), 820-9
   PubMed 12610180
4. Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A (2003)
   Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
   Oncogene, 22 (34), 5358-61
   PubMed 12917637
5. Kildal W, Kraggerud SM, Abeler VM, Heim S, Tropé CG, Kristensen GB, Risberg B, Lothe RA, Danielsen HE (2003)
   Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
   Hum Pathol, 34 (9), 946-9
   PubMed 14562293
6. Kraggerud SM, Lee MP, Skotheim RI, Stenwig AE, Fosså SD, Feinberg AP, Lothe RA (2003)
   Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors
   Cancer Genet Cytogenet, 147 (1), 1-8
   PubMed 14580764
7. Løvig T, Thorstensen L, Hofstad B, Andersen SN, Clausen OP, Vatn M, Lothe RA, Rognum TO (2003)
   Genetic and protein markers related to in situ growth and multiplicity in small sporadic colorectal adenomas
   Scand J Gastroenterol, 38 (3), 298-306
   PubMed 12737446
8. Skotheim RI, Abeler VM, Nesland JM, Fosså SD, Holm R, Wagner U, Flørenes VA, Aass N, Kallioniemi OP, Lothe RA (2003)
   Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays
   Neoplasia, 5 (5), 397-404
   PubMed 14670177
9. Skotheim RI, Kallioniemi A, Bjerkhagen B, Mertens F, Brekke HR, Monni O, Mousses S, Mandahl N, Soeter G, Nesland JM, Smeland S, Kallioniemi OP, Lothe RA (2003)
   Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome
   J Clin Oncol, 21 (24), 4586-91
   PubMed 14673046
10. Skotheim RI, Korkmaz KS, Klokk TI, Abeler VM, Korkmaz CG, Nesland JM, Fosså SD, Lothe RA, Saatcioglu F (2003)
    NKX3.1 expression is lost in testicular germ cell tumors
    Am J Pathol, 163 (6), 2149-54
    PubMed 14633588
11. Skotheim RI, Lothe RA (2003)
    The testicular germ cell tumour genome
    APMIS, 111 (1), 136-50; discussion 50-1
    PubMed 12752254
12. Thorstensen L, Holm R, Lothe RA, Tropé C, Carvalho B, Sobrinho-Simoes M, Seruca R (2003)
    WNT-inducible signaling pathway protein 3, WISP-3, is mutated in microsatellite unstable gastrointestinal carcinomas but not in endometrial carcinomas
    Gastroenterology, 124 (1), 270-1
    PubMed 12512062

Publications 2002

1. Kleivi K, Lothe RA, Heim S, Tsarouha H, Kraggerud SM, Pandis N, Papadopoulou A, Andersen J, Jakobsen KS, Teixeira MR (2002)
   Genome profiling of breast cancer cells selected against in vitro shows copy number changes
   Genes Chromosomes Cancer, 33 (3), 304-9
   PubMed 11807988
2. Kraggerud SM, Aman P, Holm R, Stenwig AE, Fosså SD, Nesland JM, Lothe RA (2002)
   Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis
   Cancer Res, 62 (2), 512-7
   PubMed 11809703
3. Kraggerud SM, Skotheim RI, Szymanska J, Eknaes M, Fosså SD, Stenwig AE, Peltomäki P, Lothe RA (2002)
   Genome profiles of familial/bilateral and sporadic testicular germ cell tumors
   Genes Chromosomes Cancer, 34 (2), 168-74
   PubMed 11979550
4. Langerød A, Bukholm IR, Bregård A, Lønning PE, Andersen TI, Rognum TO, Meling GI, Lothe RA, Børresen-Dale AL (2002)
   The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas
   Cancer Epidemiol Biomarkers Prev, 11 (12), 1684-8
   PubMed 12496062
5. Løvig T, Andersen SN, Thorstensen L, Diep CB, Meling GI, Lothe RA, Rognum TO (2002)
   Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis
   Br J Cancer, 87 (7), 756-62
   PubMed 12232760
6. Løvig T, Meling GI, Diep CB, Thorstensen L, Norheim Andersen S, Lothe RA, Rognum TO (2002)
   APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status
   Scand J Gastroenterol, 37 (10), 1184-93
   PubMed 12408524
7. Skotheim RI, Monni O, Mousses S, Fosså SD, Kallioniemi OP, Lothe RA, Kallioniemi A (2002)
   New insights into testicular germ cell tumorigenesis from gene expression profiling
   Cancer Res, 62 (8), 2359-64
   PubMed 11956097
8. Smiraglia DJ, Szymanska J, Kraggerud SM, Lothe RA, Peltomäki P, Plass C (2002)
   Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors
   Oncogene, 21 (24), 3909-16
   PubMed 12032829
9. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
   Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
   Oncogene, 21 (57), 8878-84
   PubMed 12483540

Publications 2001

1. Bomme L, Lothe RA, Bardi G, Fenger C, Kronborg O, Heim S (2001)
   Assessments of clonal composition of colorectal adenomas by FISH analysis of chromosomes 1, 7, 13 and 20
   Int J Cancer, 92 (6), 816-23
   PubMed 11351301
2. Duval A, Iacopetta B, Thorstensen L, Meling GI, Lothe RA, Thuille B, Suraweera N, Thomas G, Hamelin R (2001)
   Gender difference for mismatch repair deficiency in human colorectal cancer
   Gastroenterology, 121 (4), 1026-7
   PubMed 11665694
3. Gjertsen MK, Buanes T, Rosseland AR, Bakka A, Gladhaug I, Søreide O, Eriksen JA, Møller M, Baksaas I, Lothe RA, Saeterdal I, Gaudernack G (2001)
   Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
   Int J Cancer, 92 (3), 441-50
   PubMed 11291084
4. Lothe RA, Smith-Sørensen B, Hektoen M, Stenwig AE, Mandahl N, Saeter G, Mertens F (2001)
   Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors
   Genes Chromosomes Cancer, 30 (2), 202-6
   PubMed 11135438
5. Salahshor S, Hou H, Diep CB, Loukola A, Zhang H, Liu T, Chen J, Iselius L, Rubio C, Lothe RA, Aaltonen L, Sun XF, Lindmark G, Lindblom A (2001)
   A germline E-cadherin mutation in a family with gastric and colon cancer
   Int J Mol Med, 8 (4), 439-43
   PubMed 11562785
6. Skotheim RI, Diep CB, Kraggerud SM, Jakobsen KS, Lothe RA (2001)
   Evaluation of loss of heterozygosity/allelic imbalance scoring in tumor DNA
   Cancer Genet Cytogenet, 127 (1), 64-70
   PubMed 11408068
7. Skotheim RI, Kraggerud SM, Fosså SD, Stenwig AE, Gedde-Dahl T, Danielsen HE, Jakobsen KS, Lothe RA (2001)
   Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence
   Neoplasia, 3 (3), 196-203
   PubMed 11494113
8. Teixeira MR, Tsarouha H, Kraggerud SM, Pandis N, Dimitriadis E, Andersen JA, Lothe RA, Heim S (2001)
   Evaluation of breast cancer polyclonality by combined chromosome banding and comparative genomic hybridization analysis
   Neoplasia, 3 (3), 204-14
   PubMed 11494114
9. Thorstensen L, Diep CB, Meling GI, Aagesen TH, Ahrens CH, Rognum TO, Lothe RA (2001)
   WNT1 inducible signaling pathway protein 3, WISP-3, a novel target gene in colorectal carcinomas with microsatellite instability
   Gastroenterology, 121 (6), 1275-80
   PubMed 11729105
10. Thorstensen L, Qvist H, Nesland JM, Giercksky KE, Lothe RA (2001)
    Identification of two potential suppressor gene regions on chromosome arm 14q that are commonly lost in advanced colorectal carcinomas
    Scand J Gastroenterol, 36 (12), 1327-31
    PubMed 11761025

Publications 2000

1. Esteller M, Avizienyte E, Corn PG, Lothe RA, Baylin SB, Aaltonen LA, Herman JG (2000)
   Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
   Oncogene, 19 (1), 164-8
   PubMed 10644993
2. Helland A, Kraggerud SM, Kristensen GB, Holm R, Abeler VM, Huebner K, Borresen-Dale AL, Lothe RA (2000)
   Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival
   Int J Cancer, 88 (2), 217-22
   PubMed 11004671
3. Kraggerud SM, Szymanska J, Abeler VM, Kaern J, Eknaes M, Heim S, Teixeira MR, Tropé CG, Peltomäki P, Lothe RA (2000)
   DNA copy number changes in malignant ovarian germ cell tumors
   Cancer Res, 60 (11), 3025-30
   PubMed 10850452
4. Teixeira MR, Waehre H, Lothe RA, Stenwig AE, Pandis N, Giercksky KE, Heim S (2000)
   High frequency of clonal chromosome abnormalities in prostatic neoplasms sampled by prostatectomy or ultrasound-guided needle biopsy
   Genes Chromosomes Cancer, 28 (2), 211-9
   PubMed 10825006
5. Thorstensen L, Qvist H, Heim S, Liefers GJ, Nesland JM, Giercksky KE, Lothe RA (2000)
   Evaluation of 1p losses in primary carcinomas, local recurrences and peripheral metastases from colorectal cancer patients
   Neoplasia, 2 (6), 514-22
   PubMed 11228544

Publications 1999

1. Berner JM, Sørlie T, Mertens F, Henriksen J, Saeter G, Mandahl N, Brøgger A, Myklebost O, Lothe RA (1999)
   Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors: studies of CDKN2A and other genes of the pRB pathway
   Genes Chromosomes Cancer, 26 (2), 151-60
   PubMed 10469453
2. Duval A, Iacopetta B, Ranzani GN, Lothe RA, Thomas G, Hamelin R (1999)
   Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability
   Oncogene, 18 (48), 6806-9
   PubMed 10597289
3. Kraggerud SM, Berner A, Bryne M, Pettersen EO, Fossa SD (1999)
   Spermatocytic seminoma as compared to classical seminoma: an immunohistochemical and DNA flow cytometric study
   APMIS, 107 (3), 297-302
   PubMed 10223302

Publications 1998

1. Avizienyte E, Roth S, Loukola A, Hemminki A, Lothe RA, Stenwig AE, Fosså SD, Salovaara R, Aaltonen LA (1998)
   Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors
   Cancer Res, 58 (10), 2087-90
   PubMed 9605748
2. Bomme L, Heim S, Bardi G, Fenger C, Kronborg O, Brøgger A, Lothe RA (1998)
   Allelic imbalance and cytogenetic deletion of 1p in colorectal adenomas: a target region identified between DIS199 and DIS234
   Genes Chromosomes Cancer, 21 (3), 185-94
   PubMed 9523193
3. Børresen-Dale AL, Lothe RA, Meling GI, Hainaut P, Rognum TO, Skovlund E (1998)
   TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival
   Clin Cancer Res, 4 (1), 203-10
   PubMed 9516972
4. Børresen-Dale AL, Lothe RA, Nesland JM (1998)
   [Molecular biology. Basis for increased understanding of diseases and improved diagnostics]
   Tidsskr Nor Laegeforen, 118 (11), 1681
   PubMed 9621751
5. Clausen OP, Lothe RA, Børresen-Dale AL, De Angelis P, Chen Y, Rognum TO, Meling GI (1998)
   Association of p53 accumulation with TP53 mutations, loss of heterozygosity at 17p13, and DNA ploidy status in 273 colorectal carcinomas
   Diagn Mol Pathol, 7 (4), 215-23
   PubMed 9917132
6. De Angelis PM, Stokke T, Thorstensen L, Lothe RA, Clausen OP (1998)
   Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype
   Mol Pathol, 51 (5), 254-61
   PubMed 10193519
7. Lothe RA, Blomhoff HK (1998)
   [Tumor suppressors--genes and proteins]
   Tidsskr Nor Laegeforen, 118 (12), 1887-92
   PubMed 9638059
8. Lothe RA, Hektoen M, Johnsen H, Meling GI, Andersen TI, Rognum TO, Lindblom A, Børresen-Dale AL (1998)
   The APC gene I1307K variant is rare in Norwegian patients with familial and sporadic colorectal or breast cancer
   Cancer Res, 58 (14), 2923-4
   PubMed 9679946
9. Zhou XP, Hoang JM, Li YJ, Seruca R, Carneiro F, Sobrinho-Simoes M, Lothe RA, Gleeson CM, Russell SE, Muzeau F, Fléjou JF, Hoang-Xuan K, Lidereau R, Thomas G, Hamelin R (1998)
   Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
   Genes Chromosomes Cancer, 21 (2), 101-7
   PubMed 9491320

Publications 1997

1. Breivik J, Lothe RA, Meling GI, Rognum TO, Børresen-Dale AL, Gaudernack G (1997)
   Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors
   Int J Cancer, 74 (6), 664-9
   PubMed 9421366
2. Fosså SD, De Angelis P, Kraggerud SM, Evenson D, Theodorsen L, Clausen OP (1997)
   Prediction of posttreatment spermatogenesis in patients with testicular cancer by flow cytometric sperm chromatin structure assay
   Cytometry, 30 (4), 192-6
   PubMed 9298838
3. Giercksky HE, Thorstensen L, Qvist H, Nesland JM, Lothe RA (1997)
   Comparison of genetic changes in frozen biopsies and microdissected archival material from the same colorectal liver metastases
   Diagn Mol Pathol, 6 (6), 318-25
   PubMed 9559291
4. Helland A, Børresen-Dale AL, Peltomäki P, Hektoen M, Kristensen GB, Nesland JM, de la Chapelle A, Lothe RA (1997)
   Microsatellite instability in cervical and endometrial carcinomas
   Int J Cancer, 70 (5), 499-501
   PubMed 9052745
5. Kraggerud SM, Jacobsen KD, Berner A, Stokke T, Holm R, Smedshammer L, Børresen-Dale AL, Fosså SD (1997)
   A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
   Pathol Res Pract, 193 (7), 471-8
   PubMed 9342752
6. Lothe RA (1997)
   Microsatellite instability in human solid tumors
   Mol Med Today, 3 (2), 61-8
   PubMed 9060003
7. Soares P, dos Santos NR, Seruca R, Lothe RA, Sobrinho-Simões M (1997)
   Benign and malignant thyroid lesions show instability at microsatellite loci
   Eur J Cancer, 33 (2), 293-6
   PubMed 9135503

Publications 1996

1. Lothe RA, Karhu R, Mandahl N, Mertens F, Saeter G, Heim S, Borresen-Dale AL, Kallioniemi OP (1996)
   Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis
   Cancer Res, 56 (20), 4778-81
   PubMed 8840998
2. Thorstensen L, Qvist H, Nesland JM, Giercksky KE, Lothe RA (1996)
   Allelotype profiles of local recurrences and distant metastases from colorectal-cancer patients
   Int J Cancer, 69 (6), 452-6
   PubMed 8980246

Publications 1995

1. Børresen AL, Lothe RA, Meling GI, Lystad S, Morrison P, Lipford J, Kane MF, Rognum TO, Kolodner RD (1995)
   Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas
   Hum Mol Genet, 4 (11), 2065-72
   PubMed 8589682
2. De Angelis P, Stokke T, Smedshammer L, Lothe RA, Lehne G, Chen Y, Clausen OP (1995)
   P-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo
   Br J Cancer, 72 (2), 307-11
   PubMed 7640210
3. Kraggerud SM, Sandvik JA, Pettersen EO (1995)
   Regulation of protein synthesis in human cells exposed to extreme hypoxia
   Anticancer Res, 15 (3), 683-6
   PubMed 7645943
4. Lothe RA, Andersen SN, Hofstad B, Meling GI, Peltomäki P, Heim S, Brøgger A, Vatn M, Rognum TO, Børresen AL (1995)
   Deletion of 1p loci and microsatellite instability in colorectal polyps
   Genes Chromosomes Cancer, 14 (3), 182-8
   PubMed 8589034
5. Lothe RA, Børresen AL (1995)
   [Early diagnosis of colorectal tumors]
   Tidsskr Nor Laegeforen, 115 (26), 3231-2
   PubMed 7482447
6. Lothe RA, Peltomäki P, Tommerup N, Fosså SD, Stenwig AE, Børresen AL, Nesland JM (1995)
   Molecular genetic changes in human male germ cell tumors
   Lab Invest, 73 (5), 606-14
   PubMed 7474934
7. Lothe RA, Slettan A, Saeter G, Brøgger A, Børresen AL, Nesland JM (1995)
   Alterations at chromosome 17 loci in peripheral nerve sheath tumors
   J Neuropathol Exp Neurol, 54 (1), 65-73
   PubMed 7815081
8. Seruca R, Santos NR, David L, Constância M, Barroca H, Carneiro F, Seixas M, Peltomäki P, Lothe R, Sobrinho-Simões M (1995)
   Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile
   Int J Cancer, 64 (1), 32-6
   PubMed 7665246

Publications 1994

1. Heimdal KR, Lothe RA, Fosså SD, Børresen AL (1994)
   Association studies of a polymorphism in the Wilms' tumor 1 locus in Norwegian patients with testicular cancer
   Int J Cancer, 58 (4), 523-6
   PubMed 8056449

Publications 1993

1. Deangelis P, Stokke T, Smedshammer L, Lothe R, Meling G, Rofstad M, Chen Y, Clausen O (1993)
   P53 expression is associated with a high-degree of tumor DNA aneuploidy and incidence of p53 gene mutation, and is localized to the aneuploid component in colorectal carcinomas
   Int J Oncol, 3 (2), 305-12
   PubMed 21573365
2. Heimdal K, Lothe RA, Lystad S, Holm R, Fosså SD, Børresen AL (1993)
   No germline TP53 mutations detected in familial and bilateral testicular cancer
   Genes Chromosomes Cancer, 6 (2), 92-7
   PubMed 7680893
3. Lothe RA, Hastie N, Heimdal K, Fosså SD, Stenwig AE, Børresen AL (1993)
   Frequent loss of 11p13 and 11p15 loci in male germ cell tumours
   Genes Chromosomes Cancer, 7 (2), 96-101
   PubMed 7687459
4. Lothe RA, Peltomäki P, Meling GI, Aaltonen LA, Nyström-Lahti M, Pylkkänen L, Heimdal K, Andersen TI, Møller P, Rognum TO (1993)
   Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history
   Cancer Res, 53 (24), 5849-52
   PubMed 8261392
5. Lothe RA, Saeter G, Danielsen HE, Stenwig AE, Høyheim B, O'Connell P, Børresen AL (1993)
   Genetic alterations in a malignant schwannoma from a patient with neurofibromatosis (NF1)
   Pathol Res Pract, 189 (4), 465-71; discussion 471-4
   PubMed 8351250
6. Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
   The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables
   Br J Cancer, 67 (1), 93-8
   PubMed 8427784
7. Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
   The TP53 tumour suppressor gene in colorectal carcinomas. I. Genetic alterations on chromosome 17
   Br J Cancer, 67 (1), 88-92
   PubMed 8094008
8. Peltomäki P, Lothe RA, Aaltonen LA, Pylkkänen L, Nyström-Lahti M, Seruca R, David L, Holm R, Ryberg D, Haugen A (1993)
   Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome
   Cancer Res, 53 (24), 5853-5
   PubMed 8261393
9. Ridanpää M, Lothe RA, Onfelt A, Fosså S, Børresen AL, Husgafvel-Pursiainen K (1993)
   K-ras oncogene codon 12 point mutations in testicular cancer
   Environ Health Perspect, 101 Suppl 3, 185-7
   PubMed 8143614

Publications 1992

1. Hovig E, Smith-Sørensen B, Gebhardt MC, Ryberg D, Lothe R, Børresen AL (1992)
   No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
   Genes Chromosomes Cancer, 5 (2), 97-103
   PubMed 1381957
2. Lothe RA, Fossli T, Danielsen HE, Stenwig AE, Nesland JM, Gallie B, Børresen AL (1992)
   Molecular genetic studies of tumor suppressor gene regions on chromosomes 13 and 17 in colorectal tumors
   J Natl Cancer Inst, 84 (14), 1100-8
   PubMed 1619684
3. Lothe RA, Heimdal K, Lier ME, Fosså SD, Møller P, Brøgger A (1992)
   High resolution chromosome banding in search of germ line mutations applied on testicular cancer patients
   Cancer Genet Cytogenet, 59 (1), 62-7
   PubMed 1555193
4. Peltomäki P, Lothe RA, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1992)
   Chromosome 12 in human testicular cancer: dosage changes and their parental origin
   Cancer Genet Cytogenet, 64 (1), 21-6
   PubMed 1458445
5. Tommerup N, Lothe R (1992)
   Constitutional ring chromosomes and tumour suppressor genes
   J Med Genet, 29 (12), 879-82
   PubMed 1336057

Publications 1991

1. Hovig E, Lothe R, Farrants G, Brøgger A, Fodstad O, Børresen AL (1991)
   Chromosome 13 alterations in osteosarcoma cell lines derived from a patient with previous retinoblastoma
   Cancer Genet Cytogenet, 57 (1), 31-40
   PubMed 1684533
2. Meling GI, Lothe RA, Børresen AL, Hauge S, Graue C, Clausen OP, Rognum TO (1991)
   Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis
   Br J Cancer, 64 (3), 475-80
   PubMed 1911187
3. Peltomäki P, Lothe R, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1991)
   Altered dosage of the sex chromosomes in human testicular cancer: a molecular genetic study
   Int J Cancer, 47 (4), 518-22
   PubMed 1995482

Publications 1990

1. Boudi FH, Lothe RA, Taggart RT (1990)
   Human pepsinogen A (PGA): an informative gene complex located at 11q13
   Hum Genet, 84 (3), 293-5
   PubMed 1968039
2. FOSSA SD, LANGMARK F, AASS N, ANDERSEN A, LOTHE R, BORRESEN AL (1990)
   2ND NON-GERM CELL MALIGNANCIES AFTER RADIOTHERAPY OF TESTICULAR CANCER WITH OR WITHOUT CHEMOTHERAPY
   Br. J. Cancer, 61 (4), 639-643
3. Fosså SD, Langmark F, Aass N, Andersen A, Lothe R, Børresen AL (1990)
   Second non-germ cell malignancies after radiotherapy of testicular cancer with or without chemotherapy
   Br J Cancer, 61 (4), 639-43
   PubMed 2109999
4. Lothe RA, Brøgger A, Gedde-Dahl T (1990)
   High-resolution karyotypes of eighteen Norwegian polyposis patients
   Cancer Genet Cytogenet, 47 (1), 69-72
   PubMed 2162732

Publications 1989

1. Gedde-Dahl T, Heim S, Lothe R, Bye R, Geitvik GA, Kyrkjebø HT, Hognestad J, Nygaard K, Bergan A, Olaisen B (1989)
   [The polyposis project]
   Nord Med, 104 (1), 12-5
   PubMed 2536147
2. Lothe RA, Fosså SD, Stenwig AE, Nakamura Y, White R, Børresen AL, Brøgger A (1989)
   Loss of 3p or 11p alleles is associated with testicular cancer tumors
   Genomics, 5 (1), 134-8
   PubMed 2767683

Publications 1988

1. Gedde-Dahl T, Heim S, Lothe R, Bye R, Brevik K, Geitvik GA, Kyrkjebø HT, Hognestad J, Nygaard K, Bergan A (1988)
   [The polyposis project]
   Tidsskr Nor Laegeforen, 108 (29), 2465-8
   PubMed 2905084
2. Lothe RA, Nakamura Y, Woodward S, Gedde-Dahl T, White R (1988)
   VNTR (variable number of tandem repeats) markers show loss of chromosome 17p sequences in human colorectal carcinomas
   Cytogenet Cell Genet, 48 (3), 167-9
   PubMed 2906851

Publications 1987

1. Geitvik GA, Høyheim B, Gedde-Dahl T, Grzeschik KH, Lothe R, Tomter H, Olaisen B (1987)
   The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLP
   Hum Genet, 77 (3), 205-9
   PubMed 2890568
2. Lothe RA, Gedde-Dahl T, Lier ME, Aamdahl S, Bergan A, Stenwig AE, Broegger A (1987)
   Loss of one chromosome #13 during development of a polyposis tumor
   Cancer Genet Cytogenet, 28 (2), 335-42
   PubMed 2887278

Publications 1986

1. Lothe RA, Gedde-Dahl T, Olaisen B, Bakker E, Pearson P (1986)
   Very close linkage between D2S1 and ACP1 on chromosome 2p
   Ann Hum Genet, 50 (Pt 4), 361-7
   PubMed 3481680

Publications 1985

1. Lothe RA, Frøholm LO, Westre G, Kjennerud U (1985)
   Stainer and Scholte's pertussis medium with an alternative buffer
   J Biol Stand, 13 (2), 129-34
   PubMed 2860114