Publications by Edward Leithe

22 publications found

Publications in press

1. Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E
   Endocytosis and post-endocytic sorting of connexins
   Biochim Biophys Acta (in press)
   PubMed 21996040
2. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E
   Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
   Int J Cancer (in press)
   PubMed 21866551

Publications 2012

1. Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E (2012)
   The Gap Junction Channel Protein Connexin 43 Is Covalently Modified and Regulated by SUMOylation
   J Biol Chem, 287 (19), 15851-61
   PubMed 22411987

Publications 2011

1. Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
   Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
   Traffic, 12 (9), 1211-26
   PubMed 21564451
2. Mollerup S, Hofgaard JP, Braunstein TH, Kjenseth A, Leithe E, Rivedal E, Holstein-Rathlou NH, Nielsen MS (2011)
   Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
   Cell Commun Adhes, 18 (4), 57-65
   PubMed 21936631
3. Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE (2011)
   DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
   Epigenetics, 6 (5), 602-9
   PubMed 21406965

Publications 2010

1. Kjenseth A, Fykerud T, Rivedal E, Leithe E (2010)
   Regulation of gap junction intercellular communication by the ubiquitin system
   Cell Signal, 22 (9), 1267-73
   PubMed 20206687
2. Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E (2010)
   Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
   Toxicol Appl Pharmacol, 247 (1), 10-7
   PubMed 20510257
3. Rivedal E, Witz G, Leithe E (2010)
   Gap junction intercellular communication and benzene toxicity
   Chem Biol Interact, 184 (1-2), 229-32
   PubMed 19932693

Publications 2009

1. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
   Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
   J Cell Sci, 122 (Pt 21), 3883-93
   PubMed 19808888
2. Sirnes S, Kjenseth A, Leithe E, Rivedal E (2009)
   Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
   Biochem Biophys Res Commun, 382 (1), 41-5
   PubMed 19258009

Publications 2008

1. Rivedal E, Leithe E (2008)
   The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
   Toxicol Appl Pharmacol, 232 (3), 463-8
   PubMed 18723040
2. Sirnes S, Leithe E, Rivedal E (2008)
   The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
   Biochem Biophys Res Commun, 373 (4), 597-601
   PubMed 18601906

Publications 2007

1. Leithe E, Rivedal E (2007)
   Ubiquitination of gap junction proteins
   J Membr Biol, 217 (1-3), 43-51
   PubMed 17657522

Publications 2006

1. Leithe E, Brech A, Rivedal E (2006)
   Endocytic processing of connexin43 gap junctions: a morphological study
   Biochem J, 393 (Pt 1), 59-67
   PubMed 16162097
2. Leithe E, Sirnes S, Omori Y, Rivedal E (2006)
   Downregulation of gap junctions in cancer cells
   Crit Rev Oncog, 12 (3-4), 225-56
   PubMed 17425504

Publications 2005

1. Rivedal E, Leithe E (2005)
   Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells
   Exp Cell Res, 302 (2), 143-52
   PubMed 15561096

Publications 2004

1. Leithe E, Rivedal E (2004)
   Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43
   J Cell Sci, 117 (Pt 7), 1211-20
   PubMed 14970263
2. Leithe E, Rivedal E (2004)
   Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment
   J Biol Chem, 279 (48), 50089-96
   PubMed 15371442

Publications 2003

1. Cruciani V, Leithe E, Mikalsen SO (2003)
   Ilimaquinone inhibits gap-junctional communication prior to Golgi fragmentation and block in protein transport
   Exp Cell Res, 287 (1), 130-42
   PubMed 12799189
2. Leithe E, Cruciani V, Sanner T, Mikalsen SO, Rivedal E (2003)
   Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C
   Carcinogenesis, 24 (7), 1239-45
   PubMed 12807762

Publications 2002

1. Mallardo M, Leithe E, Schleich S, Roos N, Doglio L, Krijnse Locker J (2002)
   Relationship between vaccinia virus intracellular cores, early mRNAs, and DNA replication sites
   J Virol, 76 (10), 5167-83
   PubMed 11967332