Elin H. Kure
Position: Professor, PhD, MPH
Phone: 22 78 13 77
Email:
 

Author network for Elin H. Kure by COREMINE medical


Publications 2017

Guren TK, Thomsen M, Kure EH, Sorbye H, Glimelius B, Pfeiffer P, Österlund P, Sigurdsson F, Lothe IMB, Dalsgaard AM, Skovlund E, Christoffersen T, Tveit KM (2017)
Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study
Br J Cancer, 116 (10), 1271-1278
PubMed 28399112

Thomsen M, Guren MG, Skovlund E, Glimelius B, Hjermstad MJ, Johansen JS, Kure E, Sorbye H, Pfeiffer P, Christoffersen T, Guren TK, Tveit KM (2017)
Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status
Eur J Cancer, 81, 26-35 (in press)
PubMed 28595137

Publications 2016

Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
Clin Transl Immunology, 5 (11), e109
PubMed 27990285

Mezheyeuski A, Bradic Lindh M, Guren TK, Dragomir A, Pfeiffer P, Kure EH, Ikdahl T, Skovlund E, Corvigno S, Strell C, Pietras K, Ponten F, Mulder J, Qvortrup C, Portyanko A, Tveit KM, Glimelius B, Sorbye H, Östman A (2016)
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
Oncotarget, 7 (27), 41948-41958
PubMed 27248825

Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Cancer Res, 76 (17), 5092-102
PubMed 27488532

Tarpgaard LS, Ørum-Madsen MS, Christensen IJ, Nordgaard C, Noer J, Guren TK, Glimelius B, Sorbye H, Ikdahl T, Kure EH, Tveit KM, Nielsen HJ, Pfeiffer P, Brünner N, Moreira JM (2016)
TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer
Oncotarget, 7 (37), 59441-59457
PubMed 27509063

Thomsen M, Kersten C, Sorbye H, Skovlund E, Glimelius B, Pfeiffer P, Johansen JS, Kure EH, Ikdahl T, Tveit KM, Christoffersen T, Guren TK (2016)
Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer
Oncotarget, 7 (46), 75013-75022
PubMed 27738330

Publications 2015

Andersen V, Vogel LK, Kopp TI, Sæbø M, Nonboe AW, Hamfjord J, Kure EH, Vogel U (2015)
High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence
PLoS One, 10 (3), e0119255
PubMed 25793771

Baekelandt BM, Hjermstad MJ, Nordby T, Fagerland MW, Kure EH, Heiberg T, Buanes T, Labori KJ (2015)
Preoperative cognitive function predicts survival in patients with resectable pancreatic ductal adenocarcinoma
HPB (Oxford), 18 (3), 247-54
PubMed 27017164

Bjaanæs MM, Fleischer T, Halvorsen AR, Daunay A, Busato F, Solberg S, Jørgensen L, Kure E, Edvardsen H, Børresen-Dale AL, Brustugun OT, Tost J, Kristensen V, Helland Å (2015)
Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
Mol Oncol, 10 (2), 330-43
PubMed 26601720

Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH et al. (2015)
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Nat Cell Biol, 17 (6), 816-26
PubMed 25985394

Hamfjord J, Saldova R, Stöckmann H, Sandhu V, Bowitz Lothe IM, Buanes T, Lingjærde OC, Labori KJ, Rudd PM, Kure EH (2015)
Serum N-Glycome Characterization in Patients with Resectable Periampullary Adenocarcinoma
J Proteome Res, 14 (12), 5144-56
PubMed 26515733

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
Tumour exosome integrins determine organotropic metastasis
Nature, 527 (7578), 329-35
PubMed 26524530

Kjersem JB, Thomsen M, Guren T, Hamfjord J, Carlsson G, Gustavsson B, Ikdahl T, Indrebø G, Pfeiffer P, Lingjærde O, Tveit KM, Wettergren Y, Kure EH (2015)
AGXT and ERCC2 polymorphisms are associated with clinical outcome in metastatic colorectal cancer patients treated with 5-FU/oxaliplatin
Pharmacogenomics J, 16 (3), 272-9
PubMed 26261061

Labori KJ, Katz MH, Tzeng CW, Bjørnbeth BA, Cvancarova M, Edwin B, Kure EH, Eide TJ, Dueland S, Buanes T, Gladhaug IP (2015)
Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
Acta Oncol, 55 (3), 265-77
PubMed 26213211

Sandhu V, Bowitz Lothe IM, Labori KJ, Skrede ML, Hamfjord J, Dalsgaard AM, Buanes T, Dube G, Kale MM, Sawant S, Kulkarni-Kale U, Børresen-Dale AL, Lingjærde OC, Kure EH (2015)
Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma
Mol Oncol, 10 (2), 303-16
PubMed 26590090

Publications 2014

Bjaanaes MM, Halvorsen AR, Solberg S, Jørgensen L, Dragani TA, Galvan A, Colombo F, Anderlini M, Pastorino U, Kure E, Børresen-Dale AL, Brustugun OT, Helland A (2014)
Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
Int J Cancer, 135 (8), 1812-21
PubMed 24599520

Kjersem JB, Skovlund E, Ikdahl T, Guren T, Kersten C, Dalsgaard AM, Yilmaz MK, Fokstuen T, Tveit KM, Kure EH (2014)
FCGR2A and FCGR3A polymorphisms and clinical outcome in metastatic colorectal cancer patients treated with first-line 5-fluorouracil/folinic acid and oxaliplatin +/- cetuximab
BMC Cancer, 14, 340
PubMed 24884501

Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH (2014)
Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
Mol Oncol, 9 (4), 758-71
PubMed 25579086

Tarpgaard LS, Guren TK, Glimelius B, Christensen IJ, Pfeiffer P, Kure EH, Sorbye H, Ikdahl T, Yilmaz M, Johansen JS, Tveit KM (2014)
Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study
PLoS One, 9 (2), e87746
PubMed 24498368

Vogel LK, Sæbø M, Høyer H, Kopp TI, Vogel U, Godiksen S, Frenzel FB, Hamfjord J, Bowitz-Lothe IM, Johnson E, Kure EH, Andersen V (2014)
Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis
PLoS One, 9 (8), e105254
PubMed 25166592

Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E (2014)
Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
PLoS One, 9 (8), e103873
PubMed 25148029

Publications 2013

Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
Low ABCB1 gene expression is an early event in colorectal carcinogenesis
PLoS One, 8 (8), e72119
PubMed 23977225

Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
Mol Oncol, 8 (1), 59-67
PubMed 24119443

Kure EH, Sæbø M, Stangeland AM, Hamfjord J, Hytterød S, Heggenes J, Lydersen E (2013)
Molecular responses to toxicological stressors: profiling microRNAs in wild Atlantic salmon (Salmo salar) exposed to acidic aluminum-rich water
Aquat Toxicol, 138-139, 98-104
PubMed 23728355

Publications 2012

Hamfjord J, Stangeland AM, Hughes T, Skrede ML, Tveit KM, Ikdahl T, Kure EH (2012)
Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing
PLoS One, 7 (4), e34150
PubMed 22529906

Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH (2012)
Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
BMC Cancer, 12, 534
PubMed 23167843

Kure EH, Hamfjord J, Stangeland AM, Tveit KM, Ikdahl T (2012)
KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem
Expert Rev Mol Diagn, 12 (4), 327-8
PubMed 22616697

Tveit KM, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, Sigurdsson F, Kure E, Ikdahl T, Skovlund E, Fokstuen T, Hansen F, Hofsli E, Birkemeyer E, Johnsson A, Starkhammar H, Yilmaz MK, Keldsen N, Erdal AB, Dajani O, Dahl O, Christoffersen T (2012)
Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study
J Clin Oncol, 30 (15), 1755-62
PubMed 22473155

Publications 2011

Bornholdt J, Friis S, Godiksen S, Poulsen SS, Santoni-Rugiu E, Bisgaard HC, Lothe IM, Ikdahl T, Tveit KM, Johnson E, Kure EH, Vogel LK (2011)
The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
BMC Cancer, 11, 65
PubMed 21310043

Hamfjord J, Stangeland AM, Skrede ML, Tveit KM, Ikdahl T, Kure EH (2011)
Wobble-enhanced ARMS method for detection of KRAS and BRAF mutations
Diagn Mol Pathol, 20 (3), 158-65
PubMed 21817902

Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA (2011)
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
Front Biosci (Elite Ed), 3, 1443-55
PubMed 21622148

Publications 2010

Skjelbred CF, Svendsen M, Haugan V, Eek AK, Clausen KO, Kure EH, Tuimala JT, Svendsen MV, Norppa H, Hansteen IL (2010)
Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes
Carcinogenesis, 32 (3), 399-405
PubMed 21097530

Publications 2009

Andersen V, Agerstjerne L, Jensen D, Østergaard M, Saebø M, Hamfjord J, Kure E, Vogel U (2009)
The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
BMC Med Genet, 10, 18
PubMed 19250544

Hansteen IL, Clausen KO, Haugan V, Svendsen M, Svendsen MV, Eriksen JG, Skiaker R, Hauger E, Lågeide L, Vistnes AI, Kure EH (2009)
Cytogenetic effects of exposure to 2.3 GHz radiofrequency radiation on human lymphocytes in vitro
Anticancer Res, 29 (11), 4323-30
PubMed 20032374

Hansteen IL, Lågeide L, Clausen KO, Haugan V, Svendsen M, Eriksen JG, Skiaker R, Hauger E, Vistnes AI, Kure EH (2009)
Cytogenetic effects of 18.0 and 16.5 GHz microwave radiation on human lymphocytes in vitro
Anticancer Res, 29 (8), 2885-92
PubMed 19661291

Selzer-Plon J, Bornholdt J, Friis S, Bisgaard HC, Lothe IM, Tveit KM, Kure EH, Vogel U, Vogel LK (2009)
Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
BMC Cancer, 9, 201
PubMed 19555470

Skovbjerg H, Anthonsen D, Lothe IM, Tveit KM, Kure EH, Vogel LK (2009)
Collagen mRNA levels changes during colorectal cancer carcinogenesis
BMC Cancer, 9, 136
PubMed 19422682

Publications 2008

Saebø M, Skjelbred CF, Brekke Li K, Bowitz Lothe IM, Hagen PC, Johnsen E, Tveit KM, Kure EH (2008)
CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas
Anticancer Res, 28 (4C), 2289-95
PubMed 18751408

Publications 2007

Lorentzen A, Vogel LK, Lewinsky RH, Saebø M, Skjelbred CF, Godiksen S, Hoff G, Tveit KM, Lothe IM, Ikdahl T, Kure EH, Mitchelmore C (2007)
Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
BMC Cancer, 7, 192
PubMed 17935612

Skjelbred CF, Saebø M, Hjartåker A, Grotmol T, Hansteen IL, Tveit KM, Hoff G, Kure EH (2007)
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas
BMC Cancer, 7, 228
PubMed 18093316

Publications 2006

Saebø M, Skjelbred CF, Nexø BA, Wallin H, Hansteen IL, Vogel U, Kure EH (2006)
Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas
BMC Cancer, 6, 208
PubMed 16914027

Sarebø M, Skjelbred CF, Breistein R, Lothe IM, Hagen PC, Bock G, Hansteen IL, Kure EH (2006)
Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas
BMC Cancer, 6, 71
PubMed 16545110

Skjelbred CF, Saebø M, Nexø BA, Wallin H, Hansteen IL, Vogel U, Kure EH (2006)
Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study
BMC Cancer, 6, 175
PubMed 16817948

Skjelbred CF, Saebø M, Wallin H, Nexø BA, Hagen PC, Lothe IM, Aase S, Johnson E, Hansteen IL, Vogel U, Kure EH (2006)
Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study
BMC Cancer, 6, 67
PubMed 16542436

Vogel LK, Saebø M, Skjelbred CF, Abell K, Pedersen ED, Vogel U, Kure EH (2006)
The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
BMC Cancer, 6, 176
PubMed 16820046

Publications 2005

Hansen R, Saebø M, Skjelbred CF, Nexø BA, Hagen PC, Bock G, Bowitz Lothe IM, Johnson E, Aase S, Hansteen IL, Vogel U, Kure EH (2005)
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer
Cancer Lett, 229 (1), 85-91
PubMed 15946795

Stormorken AT, Bowitz-Lothe IM, Norèn T, Kure E, Aase S, Wijnen J, Apold J, Heimdal K, Møller P (2005)
Immunohistochemistry identifies carriers of mismatch repair gene defects causing hereditary nonpolyposis colorectal cancer
J Clin Oncol, 23 (21), 4705-12
PubMed 16034045

Publications 2004

Soucek P, Skjelbred CF, Svendsen M, Kristensen T, Kure EH, Kristensen VN (2004)
Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
BMC Biotechnol, 4, 28
PubMed 15563733

Publications 2001

Kristensen VN, Kure EH, Erikstein B, Harada N, Børresen-Dale A (2001)
Genetic susceptibility and environmental estrogen-like compounds
Mutat Res, 482 (1-2), 77-82
PubMed 11535251

Publications 2000

Skaug V, Ryberg D, Kure EH, Arab MO, Stangeland L, Myking AO, Haugen A (2000)
p53 mutations in defined structural and functional domains are related to poor clinical outcome in non-small cell lung cancer patients
Clin Cancer Res, 6 (3), 1031-7
PubMed 10741731

Publications 1997

Hollstein M, Bartsch H, Wesch H, Kure EH, Mustonen R, Mühlbauer KR, Spiethoff A, Wegener K, Wiethege T, Müller KM (1997)
p53 gene mutation analysis in tumors of patients exposed to alpha-particles
Carcinogenesis, 18 (3), 511-6
PubMed 9067550

Kure EH, Andreassen A, Ovrebø S, Grzybowska E, Fiala Z, Strózyk M, Chorazy M, Haugen A (1997)
Benzo(a)pyrene-albumin adducts in humans exposed to polycyclic aromatic hydrocarbons in an industrial area of Poland
Occup Environ Med, 54 (9), 662-6
PubMed 9423579

Publications 1996

Andreassen A, Kure EH, Nielsen PS, Autrup H, Haugen A (1996)
Comparative synchronous fluorescence spectrophotometry and 32P-postlabeling analysis of PAH-DNA adducts in human lung and the relationship to TP53 mutations
Mutat Res, 368 (3-4), 275-82
PubMed 8692233

Kure EH, Ryberg D, Hewer A, Phillips DH, Skaug V, Baera R, Haugen A (1996)
p53 mutations in lung tumours: relationship to gender and lung DNA adduct levels
Carcinogenesis, 17 (10), 2201-5
PubMed 8895489

Publications 1995

Ovrebø S, Fjeldstad PE, Grzybowska E, Kure EH, Chorazy M, Haugen A (1995)
Biological monitoring of polycyclic aromatic hydrocarbon exposure in a highly polluted area of Poland
Environ Health Perspect, 103 (9), 838-43
PubMed 7498096

Publications 1994

Ryberg D, Kure E, Lystad S, Skaug V, Stangeland L, Mercy I, Børresen AL, Haugen A (1994)
p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer
Cancer Res, 54 (6), 1551-5
PubMed 8137262

Publications 1991

Rappaport SM, Kure E, Petreas M, Ting D, Woodlee J (1991)
A field method for measuring solvent vapors in exhaled air--application to styrene exposure
Scand J Work Environ Health, 17 (3), 195-204
PubMed 2068559