
| Vessela N. Kristensen | |
| Position: | Professor, Group leader |
| Phone: | +47 22 78 13 75 |
| Email: | |
Author network for Vessela N. Kristensen by COREMINE medical
Publications in press
Genome-wide association analysis identifies three new breast cancer susceptibility loci
Nat Genet (in press)
PubMed 22267197
Allele-specific disparity in breast cancer
BMC Med Genomics, 4 (1), 85 (in press)
PubMed 22188678
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc Natl Acad Sci U S A (in press)
PubMed 21908711
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
Breast Cancer Res Treat (in press)
PubMed 22048815
Publications 2012
Analyzing cancer samples with SNP arrays
Methods Mol Biol, 802, 57-72
PubMed 22130873
Publications 2011
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
Hum Mol Genet, 20 (16), 3289-303
PubMed 21596841
miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
PLoS One, 6 (2), e16915
PubMed 21364938
Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
BMC Cancer, 11, 332
PubMed 21812955
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
BMC Med Genomics, 4, 77
PubMed 22044755
Divide and conquer: the genetic basis of molecular subclassification of breast cancer
EMBO Mol Med, 3 (4), 183-5
PubMed 21394915
Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
Cancer Epidemiol Biomarkers Prev, 20 (10), 2222-31
PubMed 21795498
Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway
Brain Behav Immun, 25 (7), 1376-83
PubMed 21496483
Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
Mol Oncol, 5 (1), 61-76
PubMed 21212030
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
BMC Bioinformatics, 12, 197
PubMed 21609452
Combining gene signatures improves prediction of breast cancer survival
PLoS One, 6 (3), e17845
PubMed 21423775
Publications 2010
Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
BMC Med Genomics, 3, 9
PubMed 20302654
On the molecular biology of breast cancer
Mol Oncol, 4 (3), 171-3
PubMed 20483673
DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
Mol Cancer, 9, 68
PubMed 20338046
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
Pharmacogenomics J, 10 (6), 513-23
PubMed 20157331
NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
Mol Cancer, 9, 113
PubMed 20482849
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
Breast Cancer Res, 12 (4), R65
PubMed 20799965
The epigenetics of breast cancer
Mol Oncol, 4 (3), 242-54
PubMed 20627830
Mutations for the people
EMBO Mol Med, 2 (5), 143-5
PubMed 20461736
The genetics and epigenetics of fatigue
PM R, 2 (5), 456-65
PubMed 20656628
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
Breast Cancer Res, 12 (1), R3
PubMed 20056007
Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
Eur J Clin Pharmacol, 66 (12), 1199-205
PubMed 20665013
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol Oncol, 4 (2), 98-118
PubMed 20060370
Expression of BMI-1 and Mel-18 in breast tissue--a diagnostic marker in patients with breast cancer
BMC Cancer, 10, 686
PubMed 21162745
Allele-specific copy number analysis of tumors
Proc Natl Acad Sci U S A, 107 (39), 16910-5
PubMed 20837533
Publications 2009
Association of ESR1 gene tagging SNPs with breast cancer risk
Hum Mol Genet, 18 (6), 1131-9
PubMed 19126777
Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
Cancer Epidemiol Biomarkers Prev, 18 (5), 1610-6
PubMed 19423537
A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
Clin Cancer Res, 15 (12), 4165-73
PubMed 19509150
Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
Pharmacogenet Genomics, 19 (10), 751-9
PubMed 19741569
Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
Oncogene, 28 (44), 3926-36
PubMed 19684618
Integrated study of copy number states and genotype calls using high-density SNP arrays
Nucleic Acids Res, 37 (16), 5365-77
PubMed 19581427
Publications 2008
Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
BMC Genomics, 9, 379
PubMed 18691401
Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
Breast Cancer Res, 10 (1), R13
PubMed 18271962
ESR1 gene amplification in breast cancer: a common phenomenon?
Nat Genet, 40 (7), 807-8; author reply 810-2
PubMed 18583965
SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
Mol Oncol, 2 (1), 12-5
PubMed 19383324
Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
Genet Epidemiol, 32 (2), 168-78
PubMed 17968987
Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
Int J Cancer, 123 (3), 577-85
PubMed 18498133
Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
Genes Chromosomes Cancer, 47 (8), 680-96
PubMed 18398821
Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
Genome Res, 18 (1), 77-87
PubMed 18032726
GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
Cancer Res, 68 (14), 5562-71
PubMed 18632608
Transcriptional networks inferred from molecular signatures of breast cancer
Am J Pathol, 172 (2), 495-509
PubMed 18187569
Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients
Pharmacogenet Genomics, 18 (3), 263-73
PubMed 18300948
Publications 2007
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
BMC Cancer, 7, 197
PubMed 17956601
Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
Breast Cancer Res, 9 (1), R5
PubMed 17224074
Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
PubMed 17336217
Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
Radiat Oncol, 2, 25
PubMed 17623063
Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
Int J Cancer, 121 (11), 2532-8
PubMed 17683073
Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
PubMed 18006915
Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
Am J Epidemiol, 165 (11), 1221-30
PubMed 17404387
Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
Breast Cancer Res, 9 (6), 113
PubMed 18036273
ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
Pharmacogenet Genomics, 17 (2), 127-36
PubMed 17301692
Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review
Am J Epidemiol, 165 (2), 115-25
PubMed 17053044
A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
Bioinformatics, 23 (2), e91-8
PubMed 17237111
Publications 2006
Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
Pharmacogenet Genomics, 16 (3), 207-17
PubMed 16495780
Genetic variation in putative regulatory loci controlling gene expression in breast cancer
Proc Natl Acad Sci U S A, 103 (20), 7735-40
PubMed 16684880
Multilocus analysis of SNP and metabolic data within a given pathway
BMC Genomics, 7, 5
PubMed 16412218
A quality assessment survey of SNP genotyping laboratories
Hum Mutat, 27 (7), 711-4
PubMed 16786507
The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
Clin Cancer Res, 12 (20 Pt 1), 6000-4
PubMed 17062672
ATM variants and cancer risk in breast cancer patients from Southern Finland
BMC Cancer, 6, 209
PubMed 16914028
Analysis of SNP-expression association matrices
J Bioinform Comput Biol, 4 (2), 259-74
PubMed 16819783
Publications 2005
Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
Clin Cancer Res, 11 (2 Pt 2), 861s-4s
PubMed 15701878
Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
Clin Cancer Res, 11 (2 Pt 2), 878s-83s
PubMed 15701881
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
J Steroid Biochem Mol Biol, 95 (1-5), 105-11
PubMed 16023338
Analysis of SNP-expression association matrices
Proc IEEE Comput Syst Bioinform Conf, 135-43
PubMed 16447971
Publications 2004
Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
Int J Cancer, 110 (2), 266-70
PubMed 15069692
Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
BMC Biotechnol, 4, 28
PubMed 15563733
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
Breast Cancer Res, 6 (2), R46-55
PubMed 14979917
[Polymorphisms of CYP1B1 and COMT in breast and endometrial cancer]
Mol Biol (Mosk), 38 (3), 386-93
PubMed 15285606
Publications 2003
BUB1 infrequently mutated in human breast carcinomas
Hum Mutat, 22 (5), 420
PubMed 14517964
Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin
Eur J Hum Genet, 11 (5), 416-9
PubMed 12734548
Publications 2002
Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas
Int Arch Occup Environ Health, 75 Suppl, S86-92
PubMed 12397416
Publications 2001
Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite ATAAA repeat
Hum Mutat, 17 (3), 238-9
PubMed 11241854
[Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
Vopr Onkol, 47 (2), 156-9
PubMed 11383450
High-throughput methods for detection of genetic variation
Biotechniques, 30 (2), 318-22, 324, 326 passim
PubMed 11233601
Genetic susceptibility and environmental estrogen-like compounds
Mutat Res, 482 (1-2), 77-82
PubMed 11535251
Low frequency of E-cadherin alterations in familial breast cancer
Breast Cancer Res, 3 (3), 199-207
PubMed 11305955
Publications 2000
Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism
Mutat Res, 462 (2-3), 323-33
PubMed 10767642
Genetic variants of CYP19 (aromatase) and breast cancer risk
Oncogene, 19 (10), 1329-33
PubMed 10713674
Publications 1998
High-throughput screening for known mutations by automated analysis of single sequencing reactions
Biotechniques, 24 (5), 832-5
PubMed 9591134
A rare CYP19 (aromatase) variant may increase the risk of breast cancer
Pharmacogenetics, 8 (1), 43-8
PubMed 9511180
Publications 1997
Improved electrophoretic separation of polymorphic short tandem repeats in agarose gels using bis-benzimide
Biotechniques, 23 (4), 634-6
PubMed 9343680




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