New books on drug target discovery and validation edited by Mouldy Sioud
Target Discovery and Validation Reviews and Protocols" Volumes 1 and 2 - edited by Mouldy Sioud from the Department of Immunology at the Norwegian Radium Hospital- are recently published by Humana Press - a leading publisher of medical and scientific books.
The books review the most progressive and current methods for drug target discovery and validation. Also, they explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders.
From major journals, first or last author from the Institute for Cancer Research
Brativnyk A, Ankill J, Helland Å, Fleischer T(2024) Multi-omics analysis reveals epigenetically regulated processes and patient classification in lung adenocarcinoma Int J Cancer(in press) DOI 10.1002/ijc.34915, PubMed 38489486
Haakensen VD, Öjlert ÅK, Thunold S, Farooqi S, Nowak AK, Chin WL, Grundberg O, Szejniuk WM, Cedres S, Sørensen JB, Dalen TS, Lund-Iversen M, Bjaanæs M, Helland Å(2024) UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma - A phase II randomised trial Eur J Cancer, 202, 113973(in press) DOI 10.1016/j.ejca.2024.113973, PubMed 38447379
Zhao Z, Zobolas J, Zucknick M, Aittokallio T(2024) Tutorial on survival modeling with applications to omics data Bioinformatics(in press) DOI 10.1093/bioinformatics/btae132, PubMed 38445722
Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen Het al.(2024) Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies J Gerontol A Biol Sci Med Sci, 79(4) DOI 10.1093/gerona/glae029, PubMed 38289789
Huynh TM, Falk RS, Hellebust TP, Dale E, Astrup GL, Hjermstad MJ, Malinen E, Bjordal K, Kiserud CE, Herlofson BB, Nome R, Amdal CD(2024) Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy Radiother Oncol, 195, 110231(in press) DOI 10.1016/j.radonc.2024.110231, PubMed 38518958
Lukovic J, Pintilie M, Han K, Fyles AW, Bruce JP, Quevedo R, Pugh TJ, Fjeldbo CS, Lyng H, Milosevic MF(2024) An Immune Gene Expression Risk Score for Distant Metastases after Radiotherapy for Cervical Cancer Clin Cancer Res, 30(6), 1200-1207 DOI 10.1158/1078-0432.CCR-23-2085, PubMed 38180733