Llorente/Sandvig publish potential biomarkers for prostate cancer
Alicia Llorente and Kirsten Sandvig, Department of Biochemistry, Institute for Cancer Research and Centre for Cancer Biomedicine, have recently published in Molecular and Cellular Proteomics (impact factor 8.4) a proteomic analysis of microvesicles released from a human prostate cancer cell line. Most of the 266 proteins identified have previously been reported to be present in vesicles released from other cell types, but several proteins seem to be specific for prostate cancer cells. Since microvesicles can reach biological fluids, these proteins are thus potentially useful as new non invasive biomarkers for detection, diagnosis and/or prognosis of prostate cancer.
Llorente (left) and Sandvig
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3.
Sandvig K, Llorente A.
Mol Cell Proteomics. 2012 Mar 28. [Epub ahead of print]