Ivar Sjaastad
Position: Group leader
Phone: +47 23016797
Email:

Visit research group page at www.iemr.no

 

Author network for Ivar Sjaastad by COREMINE medical


Publications 2017

Aronsen JM, Espe EKS, Skårdal K, Hasic A, Zhang L, Sjaastad I (2017)
Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography
Am J Physiol Heart Circ Physiol, 312 (5), H932-H942
PubMed 28188213

Berntsen KS, Tollisen A, Schwartz T, Kirkhus E, Aaløkken TM, Lund MB, Flatø B, Sjaastad I, Sanner H (2017)
Submaximal Exercise Capacity in Juvenile Dermatomyositis after Longterm Disease: The Contribution of Muscle, Lung, and Heart Involvement
J Rheumatol (in press)
PubMed 28365577

Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
PubMed 28490840

Gattoni S, Treu Røe Å, Aronsen JM, Sjaastad I, Louch WE, Smith NP, Niederer SA (2017)
Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding
J Physiol (in press)
PubMed 28542952

Johansen IB, Sandblom E, Skov PV, Gräns A, Ekström A, Lunde IG, Vindas MA, Zhang L, Höglund E, Frisk M, Sjaastad I, Nilsson GE, Øverli Ø (2017)
Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids
J Exp Biol (in press)
PubMed 28476893

Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
PubMed 28529766

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JD, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
PubMed 28052262

Ottesen AH, Carlson CR, Louch WE, Dahl MB, Sandbu RA, Johansen RF, Jarstadmarken H, Bjørås M, Høiseth AD, Brynildsen J, Sjaastad I, Stridsberg M, Omland T, Christensen G, Røsjø H (2017)
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ Heart Fail, 10 (2)
PubMed 28209766

Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE (2017)
Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
Cardiovasc Res (in press)
PubMed 28472418

Publications 2016

Aronsen JM, Louch WE, Sjaastad I (2016)
Cardiomyocyte Ca2+ dynamics: clinical perspectives
Scand Cardiovasc J, 50 (2), 65-77
PubMed 26729487

Dhondup Y, Ueland T, Dahl CP, Askevold ET, Sandanger Ø, Fiane A, Ohm IK, Sjaastad I, Finsen AV, Wæhre A, Gullestad L, Aukrust P, Yndestad A, Vinge LE (2016)
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J Card Fail, 22 (10), 823-8
PubMed 27349571

Espe EK, Skårdal K, Aronsen JM, Zhang L, Sjaastad I (2016)
A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data
Magn Reson Med (in press)
PubMed 27699840

Frisk M, Ruud M, Espe EK, Aronsen JM, Røe ÅT, Zhang L, Norseng PA, Sejersted OM, Christensen GA, Sjaastad I, Louch WE (2016)
Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis
Cardiovasc Res, 112 (1), 443-51
PubMed 27226008

Hortemo KH, Lunde PK, Anonsen JH, Kvaløy H, Munkvik M, Rehn TA, Sjaastad I, Lunde IG, Aronsen JM, Sejersted OM (2016)
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
Physiol Rep, 4 (18)
PubMed 27664189

Logantha SJ, Stokke MK, Atkinson AJ, Kharche SR, Parveen S, Saeed Y, Sjaastad I, Sejersted OM, Dobrzynski H (2016)
Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 Abundance
Front Physiol, 7, 197
PubMed 27313537

Manotheepan R, Danielsen TK, Sadredini M, Anderson ME, Carlson CR, Lehnart SE, Sjaastad I, Stokke MK (2016)
Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release
Cardiovasc Res, 111 (3), 295-306
PubMed 27161030

Melleby AO, Strand ME, Romaine A, Herum KM, Skrbic B, Dahl CP, Sjaastad I, Fiane AE, Filmus J, Christensen G, Lunde IG (2016)
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
PubMed 27768722

Sadredini M, Danielsen TK, Aronsen JM, Manotheepan R, Hougen K, Sjaastad I, Stokke MK (2016)
Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
PLoS One, 11 (4), e0153887
PubMed 27096943

Schwartz T, Diederichsen LP, Lundberg IE, Sjaastad I, Sanner H (2016)
Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies
RMD Open, 2 (2), e000291
PubMed 27752355

Skårdal K, Espe EK, Zhang L, Aronsen JM, Sjaastad I (2016)
Three-Directional Evaluation of Mitral Flow in the Rat Heart by Phase-Contrast Cardiovascular Magnetic Resonance
PLoS One, 11 (3), e0150536
PubMed 26930073

Thienpont B, Aronsen JM, Robinson EL, Okkenhaug H, Loche E, Ferrini A, Brien P, Alkass K, Tomasso A, Agrawal A, Bergmann O, Sjaastad I, Reik W, Roderick HL (2016)
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy
J Clin Invest, 127 (1), 335-348
PubMed 27893464

Publications 2015

Barth Z, Nomeland Witczak B, Schwartz T, Gjesdal K, Flatø B, Koller A, Sanner H, Sjaastad I (2015)
In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset
Rheumatology (Oxford), 55 (3), 535-43
PubMed 26500284

Bolstad I, Andreassen OA, Groote I, Server A, Sjaastad I, Kapur S, Jensen J (2015)
Effects of haloperidol and aripiprazole on the human mesolimbic motivational system: A pharmacological fMRI study
Eur Neuropsychopharmacol, 25 (12), 2252-61
PubMed 26476705

Cero FT, Hillestad V, Sjaastad I, Yndestad A, Aukrust P, Ranheim T, Lunde IG, Olsen MB, Lien E, Zhang L, Haugstad SB, Løberg EM, Christensen G, Larsen KO, Skjønsberg OH (2015)
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
PubMed 26071556

Dhondup Y, Sjaastad I, Scott H, Sandanger Ø, Zhang L, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
PubMed 26461521

Espe EK, Aronsen JM, Eriksen GS, Zhang L, Smiseth OA, Edvardsen T, Sjaastad I, Eriksen M (2015)
Assessment of regional myocardial work in rats
Circ Cardiovasc Imaging, 8 (2), e002695
PubMed 25673647

Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2015)
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
J Biol Chem, 291 (9), 4561-79
PubMed 26668322

Herum KM, Lunde IG, Skrbic B, Louch WE, Hasic A, Boye S, Unger A, Brorson SH, Sjaastad I, Tønnessen T, Linke WA, Gomez MF, Christensen G (2015)
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc Res, 106 (2), 217-26
PubMed 25587045

Hortemo KH, Aronsen JM, Lunde IG, Sjaastad I, Lunde PK, Sejersted OM (2015)
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
Physiol Rep, 3 (2)
PubMed 25713325

Krohn-Hansen D, Zhang L, Haaskjold E, Meling TR, Nicolaissen B, Sjaastad I (2015)
Surgical anatomy of the superior orbit on ultra-high-resolution MRI at 9.4 Tesla
J Plast Surg Hand Surg, 49 (5), 284-288
PubMed 25946966

Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
PubMed 26055793

Ottesen AH, Louch WE, Carlson CR, Landsverk OJ, Kurola J, Johansen RF, Moe MK, Aronsen JM, Høiseth AD, Jarstadmarken H, Nygård S, Bjørås M, Sjaastad I, Pettilä V, Stridsberg M, Omland T, Christensen G, Røsjø H (2015)
Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling
J Am Coll Cardiol, 65 (4), 339-51
PubMed 25634832

Skrbic B, Engebretsen KV, Strand ME, Lunde IG, Herum KM, Marstein HS, Sjaastad I, Lunde PK, Carlson CR, Christensen G, Bjørnstad JL, Tønnessen T (2015)
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc Res, 106 (1), 32-42
PubMed 25694587

Strand ME, Aronsen JM, Braathen B, Sjaastad I, Kvaløy H, Tønnessen T, Christensen G, Lunde IG (2015)
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J Mol Cell Cardiol, 88, 133-44
PubMed 26449522

Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M (2015)
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2
Circ Res, 117 (8), 707-19
PubMed 26243800

Publications 2014

Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I (2014)
Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α2 activity
J Physiol, 593 (6), 1509-21
PubMed 25772299

Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
PubMed 24486508

Engebretsen KV, Skårdal K, Bjørnstad S, Marstein HS, Skrbic B, Sjaastad I, Christensen G, Bjørnstad JL, Tønnessen T (2014)
Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5
J Mol Cell Cardiol, 76, 148-57
PubMed 25169971

Finsen AV, Ueland T, Sjaastad I, Ranheim T, Ahmed MS, Dahl CP, Askevold ET, Aakhus S, Husberg C, Fiane AE, Lipp M, Gullestad L, Christensen G, Aukrust P, Yndestad A (2014)
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling
PLoS One, 9 (11), e112172
PubMed 25398010

Hillestad V, Espe EK, Cero F, Larsen KO, Sjaastad I, Nygård S, Skjønsberg OH, Christensen G (2014)
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
PubMed 25182570

Manotheepan R, Saberniak J, Danielsen TK, Edvardsen T, Sjaastad I, Haugaa KH, Stokke MK (2014)
Effects of individualized exercise training in patients with catecholaminergic polymorphic ventricular tachycardia type 1
Am J Cardiol, 113 (11), 1829-33
PubMed 24837260

Melsom CB, Hussain RI, Ørstavik Ø, Aronsen JM, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2014)
Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
Naunyn Schmiedebergs Arch Pharmacol, 387 (12), 1177-86
PubMed 25216690

Moltzau LR, Aronsen JM, Meier S, Skogestad J, Ørstavik Ø, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
J Pharmacol Exp Ther, 350 (3), 681-90
PubMed 25022512

Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
PubMed 24424715

Nordbø O, Lamata P, Land S, Niederer S, Aronsen JM, Louch WE, Sjaastad I, Martens H, Gjuvsland AB, Tøndel K, Torp H, Lohezic M, Schneider JE, Remme EW, Smith N, Omholt SW, Vik JO (2014)
A computational pipeline for quantification of mouse myocardial stiffness parameters
Comput Biol Med, 53, 65-75
PubMed 25129018

Sanner H, Schwartz T, Flatø B, Vistnes M, Christensen G, Sjaastad I (2014)
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
PubMed 24647150

Sanner H, Sjaastad I, Flatø B (2014)
Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool
Rheumatology (Oxford), 53 (9), 1578-85
PubMed 24692575

Schwartz T, Sjaastad I, Flatø B, Vistnes M, Christensen G, Sanner H (2014)
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
PubMed 24996906

Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
PLoS One, 9 (3), e89621
PubMed 24595230

Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
PubMed 25336645

Publications 2013

Engebretsen KV, Lunde IG, Strand ME, Waehre A, Sjaastad I, Marstein HS, Skrbic B, Dahl CP, Askevold ET, Christensen G, Bjørnstad JL, Tønnessen T (2013)
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J, 280 (10), 2382-98
PubMed 23480731

Engebretsen KV, Waehre A, Bjørnstad JL, Skrbic B, Sjaastad I, Behmen D, Marstein HS, Yndestad A, Aukrust P, Christensen G, Tønnessen T (2013)
Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse
J Appl Physiol (1985), 114 (8), 988-97
PubMed 23412898

Espe EK, Aronsen JM, Skårdal K, Schneider JE, Zhang L, Sjaastad I (2013)
Novel insight into the detailed myocardial motion and deformation of the rodent heart using high-resolution phase contrast cardiovascular magnetic resonance
J Cardiovasc Magn Reson, 15, 82
PubMed 24034168

Espe EK, Zhang L, Sjaastad I (2013)
Unwrapping eddy current compensation: improved compensation of eddy current induced baseline shifts in high-resolution phase-contrast MRI at 9.4 Tesla
Magn Reson Med, 72 (4), 1096-102
PubMed 24264935

Land S, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sjaastad I, Sejersted OM, Smith NP (2013)
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice
Biophys J, 104 (6), 1349-56
PubMed 23528094

Louch WE, Hake J, Mørk HK, Hougen K, Skrbic B, Ursu D, Tønnessen T, Sjaastad I, Sejersted OM (2013)
Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?
J Mol Cell Cardiol, 58, 41-52
PubMed 23376034

Moltzau LR, Aronsen JM, Meier S, Nguyen CH, Hougen K, Ørstavik Ø, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br J Pharmacol, 170 (2), 366-79
PubMed 23808942

Schwartz T, Sanner H, Gjesdal O, Flatø B, Sjaastad I (2013)
In juvenile dermatomyositis, cardiac systolic dysfunction is present after long-term follow-up and is predicted by sustained early skin activity
Ann Rheum Dis, 73 (10), 1805-10
PubMed 23881732

Slettalokken G, Rehn TA, Munkvik M, Rud B, Nymark BS, Lunde PK, Sjaastad I, Sejersted OM, Hallen J (2013)
Normal training response in skeletal muscle of post-infarction heart failure patients
Eur. J. Sport Sci., 13 (2), 231-239

Solberg A, Robertson AB, Aronsen JM, Rognmo Ø, Sjaastad I, Wisløff U, Klungland A (2013)
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
PubMed 23572141

Stokke MK, Tovsrud N, Louch WE, Øyehaug L, Hougen K, Sejersted OM, Swift F, Sjaastad I (2013)
I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation
Cardiovasc Res, 98 (2), 315-25
PubMed 23417043

Strand ME, Herum KM, Rana ZA, Skrbic B, Askevold ET, Dahl CP, Vistnes M, Hasic A, Kvaløy H, Sjaastad I, Carlson CR, Tønnessen T, Gullestad L, Christensen G, Lunde IG (2013)
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J, 280 (10), 2228-47
PubMed 23374111

Øyehaug L, Loose KØ, Jølle GF, Røe ÅT, Sjaastad I, Christensen G, Sejersted OM, Louch WE (2013)
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity
Biophys J, 104 (8), 1685-97
PubMed 23601316

Publications 2012

Brattelid T, Qvigstad E, Moltzau LR, Bekkevold SV, Sandnes DL, Birkeland JA, Skomedal T, Osnes JB, Sjaastad I, Levy FO (2012)
The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure
PLoS One, 7 (9), e45489
PubMed 23029047

Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL (2012)
Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy
J Cell Biol, 199 (5), 783-98
PubMed 23166348

Espe EK, Aronsen JM, Skrbic B, Skulberg VM, Schneider JE, Sejersted OM, Zhang L, Sjaastad I (2012)
Improved MR phase-contrast velocimetry using a novel nine-point balanced motion-encoding scheme with increased robustness to eddy current effects
Magn Reson Med, 69 (1), 48-61
PubMed 22392844

Herum KM, Lunde IG, Skrbic B, Florholmen G, Behmen D, Sjaastad I, Carlson CR, Gomez MF, Christensen G (2012)
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J Mol Cell Cardiol, 54, 73-81
PubMed 23178899

Hussain RI, Aronsen JM, Afzal F, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
J Mol Cell Cardiol, 56, 129-38
PubMed 23220156

Land S, Niederer SA, Aronsen JM, Espe EK, Zhang L, Louch WE, Sjaastad I, Sejersted OM, Smith NP (2012)
An analysis of deformation-dependent electromechanical coupling in the mouse heart
J Physiol, 590 (18), 4553-69
PubMed 22615436

Louch WE, Stokke MK, Sjaastad I, Christensen G, Sejersted OM (2012)
No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium
Physiology (Bethesda), 27 (5), 308-23
PubMed 23026754

Rehn TA, Munkvik M, Lunde PK, Sjaastad I, Sejersted OM (2012)
Intrinsic skeletal muscle alterations in chronic heart failure patients: a disease-specific myopathy or a result of deconditioning?
Heart Fail Rev, 17 (3), 421-36
PubMed 21996779

Røsjø H, Stridsberg M, Florholmen G, Stensløkken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, Øie E, Louch WE, Omland T, Christensen G (2012)
Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties
PLoS One, 7 (5), e37401
PubMed 22655045

Schwartz T, Magdi G, Steen TW, Sjaastad I (2012)
HIV as a risk factor for cardiac disease in Botswana: a cross-sectional study
Int Health, 4 (1), 30-7
PubMed 24030878

Skrbic B, Bjørnstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygård S, Bjørnstad S, Christensen G, Tønnessen T (2012)
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol, 32 (2), 133-42
PubMed 23220517

Stokke MK, Rivelsrud F, Sjaastad I, Sejersted OM, Swift F (2012)
From global to local: a new understanding of cardiac electromechanical coupling
Tidsskr Nor Laegeforen, 132 (12-13), 1457-60
PubMed 22766818

Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
PubMed 22345433

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P (2012)
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
PubMed 22427939

Zalvidea S, André L, Loyer X, Cassan C, Sainte-Marie Y, Thireau J, Sjaastad I, Heymes C, Pasquié JL, Cazorla O, Aimond F, Richard S (2012)
ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction
Curr Mol Med, 12 (2), 206-17
PubMed 22280358

Publications 2011

Afzal F, Aronsen JM, Moltzau LR, Sjaastad I, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2011)
Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
Br J Pharmacol, 162 (1), 54-71
PubMed 21133887

Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
PubMed 21901315

Bjørnstad JL, Skrbic B, Marstein HS, Hasic A, Sjaastad I, Louch WE, Florholmen G, Christensen G, Tønnessen T (2011)
Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload
Cardiovasc Res, 93 (1), 100-10
PubMed 22049534

Bjørnstad JL, Skrbic B, Sjaastad I, Bjørnstad S, Christensen G, Tønnessen T (2011)
A mouse model of reverse cardiac remodelling following banding-debanding of the ascending aorta
Acta Physiol (Oxf), 205 (1), 92-102
PubMed 21974781

Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
PubMed 22164265

Hussain RI, Afzal F, Mørk HK, Aronsen JM, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2011)
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
Br J Pharmacol, 162 (4), 908-16
PubMed 21039419

Larsen KO, Yndestad A, Sjaastad I, Løberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjønsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
PubMed 21498626

Lunde IG, Aronsen JM, Kvaløy H, Qvigstad E, Sjaastad I, Tønnessen T, Christensen G, Grønning-Wang LM, Carlson CR (2011)
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol Genomics, 44 (2), 162-72
PubMed 22128088

Munkvik M, Lunde PK, Aronsen JM, Birkeland JA, Sjaastad I, Sejersted OM (2011)
Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure
PLoS One, 6 (7), e22695
PubMed 21799933

Russell K, Smiseth OA, Gjesdal O, Qvigstad E, Norseng PA, Sjaastad I, Opdahl A, Skulstad H, Edvardsen T, Remme EW (2011)
Mechanism of prolonged electromechanical delay in late activated myocardium during left bundle branch block
Am J Physiol Heart Circ Physiol, 301 (6), H2334-43
PubMed 21984549

Schwartz T, Sanner H, Husebye T, Flatø B, Sjaastad I (2011)
Cardiac dysfunction in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (5), 766-71
PubMed 21216816

Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I (2011)
Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content
Cardiovasc Res, 90 (3), 503-12
PubMed 21242164

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
PubMed 21533157

Publications 2010

Bjørnstad JL, Sjaastad I, Nygård S, Hasic A, Ahmed MS, Attramadal H, Finsen AV, Christensen G, Tønnessen T (2010)
Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload
Eur Heart J, 32 (2), 236-45
PubMed 20525982

Ericsson M, Andersson KB, Amundsen BH, Torp SH, Sjaastad I, Christensen G, Sejersted OM, Ellingsen Ø (2010)
High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
J Appl Physiol (1985), 108 (5), 1311-20
PubMed 20167673

Ericsson M, Sjåland C, Andersson KB, Sjaastad I, Christensen G, Sejersted OM, Ellingsen Ø (2010)
Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
J Appl Physiol (1985), 109 (6), 1749-55
PubMed 20864565

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
PubMed 20802136

Louch WE, Hake J, Jølle GF, Mørk HK, Sjaastad I, Lines GT, Sejersted OM (2010)
Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes
Biophys J, 99 (5), 1377-86
PubMed 20816049

Munkvik M, Rehn TA, Slettaløkken G, Hasic A, Hallén J, Sjaastad I, Sejersted OM, Lunde PK (2010)
Training effects on skeletal muscle calcium handling in human chronic heart failure
Med Sci Sports Exerc, 42 (5), 847-55
PubMed 19996998

Røsjø H, Husberg C, Dahl MB, Stridsberg M, Sjaastad I, Finsen AV, Carlson CR, Oie E, Omland T, Christensen G (2010)
Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium
Circ Heart Fail, 3 (4), 503-11
PubMed 20519641

Sanner H, Aaløkken TM, Gran JT, Sjaastad I, Johansen B, Flatø B (2010)
Pulmonary outcome in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (1), 86-91
PubMed 20805295

Slettaløkken G, Rehn TA, Munkvik M, Rud B, Sökjer-Petersen M, Lunde PK, Sjaastad I, Sejersted OM, Hallén J (2010)
Preserved metabolic reserve capacity in skeletal muscle of post-infarction heart failure patients
Scand J Med Sci Sports, 22 (2), 199-206
PubMed 20874858

Swift F, Tovsrud N, Sjaastad I, Sejersted OM, Niggli E, Egger M (2010)
Functional coupling of alpha(2)-isoform Na(+)/K(+)-ATPase and Ca(2+) extrusion through the Na(+)/Ca(2+)-exchanger in cardiomyocytes
Cell Calcium, 48 (1), 54-60
PubMed 20667414

Tømte Ø, Sjaastad I, Wik L, Kuzovlev A, Eriksen M, Norseng PA, Sunde K (2010)
Discriminating the effect of accelerated compression from accelerated decompression during high-impulse CPR in a porcine model of cardiac arrest
Resuscitation, 81 (4), 488-92
PubMed 20122780

Vistnes M, Waehre A, Nygård S, Sjaastad I, Andersson KB, Husberg C, Christensen G (2010)
Circulating cytokine levels in mice with heart failure are etiology dependent
J Appl Physiol (1985), 108 (5), 1357-64
PubMed 20224000

Publications 2009

Andersson KB, Birkeland JA, Finsen AV, Louch WE, Sjaastad I, Wang Y, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G (2009)
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
J Mol Cell Cardiol, 47 (2), 180-7
PubMed 19328205

Andersson KB, Finsen AV, Sjåland C, Winer LH, Sjaastad I, Odegaard A, Louch WE, Wang Y, Chen J, Chien KR, Sejersted OM, Christensen G (2009)
Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models
Cell Calcium, 46 (3), 219-25
PubMed 19692123

Hussain RI, Qvigstad E, Birkeland JA, Eikemo H, Glende A, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2009)
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation
Br J Pharmacol, 156 (4), 575-86
PubMed 19159405

Iversen PO, Andersson KB, Finsen AV, Sjaastad I, von Lueder TG, Sejersted OM, Attramadal H, Christensen G (2009)
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am J Physiol Regul Integr Comp Physiol, 298 (3), R808-14
PubMed 20032264

Kjekshus JK, Torp-Pedersen C, Gullestad L, Køber L, Edvardsen T, Olsen IC, Sjaastad I, Qvigstad E, Skomedal T, Osnes JB, Levy FO (2009)
Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure
Eur J Heart Fail, 11 (8), 771-8
PubMed 19567409

Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM (2009)
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J Physiol, 588 (Pt 3), 465-78
PubMed 20008467

Mørk HK, Sjaastad I, Sejersted OM, Louch WE (2009)
Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice
Am J Physiol Heart Circ Physiol, 296 (4), H1069-79
PubMed 19201998

Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB (2009)
Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
Cardiovasc Res, 85 (4), 763-72
PubMed 19900965

Rehn TA, Borge BA, Lunde PK, Munkvik M, Sneve ML, Grøndahl F, Aronsen JM, Sjaastad I, Prydz K, Kolset SO, Wiig H, Sejersted OM, Iversen PO (2009)
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
Am J Physiol Regul Integr Comp Physiol, 297 (1), R26-33
PubMed 19339678

Sanner H, Gran JT, Sjaastad I, Flatø B (2009)
Cumulative organ damage and prognostic factors in juvenile dermatomyositis: a cross-sectional study median 16.8 years after symptom onset
Rheumatology (Oxford), 48 (12), 1541-7
PubMed 19776224

Sharikabad MN, Aronsen JM, Haugen E, Pedersen J, Møller AS, Mørk HK, Aass HC, Sejersted OM, Sjaastad I, Brørs O (2009)
Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
Am J Physiol Heart Circ Physiol, 296 (3), H787-95
PubMed 19136604

Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW (2009)
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc Res, 86 (1), 63-71
PubMed 20019150

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjønsberg OH, Pedersen TM, Anfinsen OG, Damås JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
PubMed 19196915

Publications 2008

Afzal F, Andressen KW, Mørk HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
Br J Pharmacol, 155 (7), 1005-14
PubMed 18846035

Bøkenes J, Aronsen JM, Birkeland JA, Henriksen UL, Louch WE, Sjaastad I, Sejersted OM (2008)
Slow contractions characterize failing rat hearts
Basic Res Cardiol, 103 (4), 328-44
PubMed 18347833

Larsen KO, Lygren B, Sjaastad I, Krobert KA, Arnkvaern K, Florholmen G, Larsen AK, Levy FO, Taskén K, Skjønsberg OH, Christensen G (2008)
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A
Cardiovasc Res, 80 (1), 47-54
PubMed 18599478

Swift F, Birkeland JA, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure
Cardiovasc Res, 78 (1), 71-8
PubMed 18203708

Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na(+)/Ca(2+)-exchanger activity due to downregulation of Na(+)/K(+)-ATPase alpha(2)-isoform in heart failure (vol 78, pg 71, 2008)
Cardiovasc. Res., 79 (2), 352

Publications 2007

Birkeland JA, Swift F, Tovsrud N, Enger U, Lunde PK, Qvigstad E, Levy FO, Sejersted OM, Sjaastad I (2007)
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Am J Physiol Heart Circ Physiol, 293 (4), H2367-76
PubMed 17660386

Brattelid T, Qvigstad E, Birkeland JA, Swift F, Bekkevold SV, Krobert KA, Sejersted OM, Skomedal T, Osnes JB, Levy FO, Sjaastad I (2007)
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle
J Mol Cell Cardiol, 43 (6), 767-79
PubMed 17936780

Brattelid T, Tveit K, Birkeland JA, Sjaastad I, Qvigstad E, Krobert KA, Hussain RI, Skomedal T, Osnes JB, Levy FO (2007)
Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure--a quantitative RT-PCR study and the question of normalisation
Basic Res Cardiol, 102 (3), 198-208
PubMed 17370034

Mørk HK, Sjaastad I, Sande JB, Periasamy M, Sejersted OM, Louch WE (2007)
Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure
J Mol Cell Cardiol, 43 (2), 177-86
PubMed 17574269

Swift F, Tovsrud N, Enger UH, Sjaastad I, Sejersted OM (2007)
The Na+/K+-ATPase alpha2-isoform regulates cardiac contractility in rat cardiomyocytes
Cardiovasc Res, 75 (1), 109-17
PubMed 17442282

Publications 2006

Birkeland JA, Sjaastad I, Brattelid T, Qvigstad E, Moberg ER, Krobert KA, Bjørnerheim R, Skomedal T, Sejersted OM, Osnes JB, Levy FO (2006)
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
Br J Pharmacol, 150 (2), 143-52
PubMed 17160012

Larsen KO, Sjaastad I, Svindland A, Krobert KA, Skjønsberg OH, Christensen G (2006)
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice
Am J Physiol Heart Circ Physiol, 291 (2), H507-16
PubMed 16582020

Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM (2006)
T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction
J Physiol, 574 (Pt 2), 519-33
PubMed 16709642

Swift F, Strømme TA, Amundsen B, Sejersted OM, Sjaastad I (2006)
Slow diffusion of K+ in the T tubules of rat cardiomyocytes
J Appl Physiol (1985), 101 (4), 1170-6
PubMed 16763106

Publications 2005

Birkeland JA, Sejersted OM, Taraldsen T, Sjaastad I (2005)
EC-coupling in normal and failing hearts
Scand Cardiovasc J, 39 (1-2), 13-23
PubMed 16097409

Bøkenes J, Sjaastad I, Sejersted OM (2005)
Artifactual contractions triggered by field stimulation of cardiomyocytes
J Appl Physiol (1985), 98 (5), 1712-9
PubMed 15640393

Cunderlíková B, Moan J, Sjaastad I (2005)
pH dependent uptake of porphyrin-type photosensitizers by solid tumor cells in vitro is not induced by modification of transmembrane potential
Cancer Lett, 222 (1), 39-47
PubMed 15837539

Qvigstad E, Brattelid T, Sjaastad I, Andressen KW, Krobert KA, Birkeland JA, Sejersted OM, Kaumann AJ, Skomedal T, Osnes JB, Levy FO (2005)
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
Cardiovasc Res, 65 (4), 869-78
PubMed 15721867

Qvigstad E, Sjaastad I, Brattelid T, Nunn C, Swift F, Birkeland JA, Krobert KA, Andersen GØ, Sejersted OM, Osnes JB, Levy FO, Skomedal T (2005)
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
Circ Res, 97 (3), 268-76
PubMed 16002744

Qvigstad E, Sjaastad I, Bøkenes J, Schiander I, Solberg L, Sejersted OM, Osnes JB, Skomedal T (2005)
Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure
Eur J Pharmacol, 516 (1), 51-9
PubMed 15916756

Schiøtz Thorud HM, Stranda A, Birkeland JA, Lunde PK, Sjaastad I, Kolset SO, Sejersted OM, Iversen PO (2005)
Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure
Am J Physiol Regul Integr Comp Physiol, 289 (2), R389-R394
PubMed 15802562

Sjaastad I, Birkeland JA, Ferrier G, Howlett S, Skomedal T, Bjørnerheim R, Wasserstrom JA, Sejersted OM (2005)
Defective excitation-contraction coupling in hearts of rats with congestive heart failure
Acta Physiol Scand, 184 (1), 45-58
PubMed 15847643

Thorud HM, Verburg E, Lunde PK, Strømme TA, Sjaastad I, Sejersted OM (2005)
Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure
J Appl Physiol (1985), 99 (4), 1500-7
PubMed 15932960

Publications 2004

Finsen AV, Christensen G, Sjaastad I (2004)
Echocardiographic parameters discriminating myocardial infarction with pulmonary congestion from myocardial infarction without congestion in the mouse
J Appl Physiol (1985), 98 (2), 680-9
PubMed 15475595

Grund F, Tjomsland O, Sjaastad I, Ilebekk A, Kirkebøen KA (2004)
Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine
Lab Anim, 38 (1), 70-8
PubMed 14979991

Publications 2003

Qvigstad E, Osnes JB, Sandnes D, Schiander I, Bøkenes J, Sjaastad I, Skomedal T (2003)
Carvedilol blockade of rat myocardial alpha1-adrenoceptors
Eur J Pharmacol, 481 (1), 83-9
PubMed 14637179

Sjaastad I, Schiander I, Sjetnan A, Qvigstad E, Bøkenes J, Sandnes D, Osnes JB, Sejersted OM, Skomedal T (2003)
Increased contribution of alpha 1- vs. beta-adrenoceptor-mediated inotropic response in rats with congestive heart failure
Acta Physiol Scand, 177 (4), 449-58
PubMed 12648162

Sjaastad I, Wasserstrom JA, Sejersted OM (2003)
Heart failure -- a challenge to our current concepts of excitation-contraction coupling
J Physiol, 546 (Pt 1), 33-47
PubMed 12509477

Swift F, Sjaastad I, Sejersted OM (2003)
[Does altered regulation of Na+ cause reduced myocardial contractility in heart failure?]
Tidsskr Nor Laegeforen, 123 (21), 3036-40
PubMed 14618171

Thomas MJ, Sjaastad I, Andersen K, Helm PJ, Wasserstrom JA, Sejersted OM, Ottersen OP (2003)
Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes
J Mol Cell Cardiol, 35 (11), 1325-37
PubMed 14596789

Publications 2002

Johannsson E, Sejersted OM, Lunde PK, Sjaastad I, Thomas MJ, Bergersen L, Blackstad TW, Ottersen OP, Heddle C, Halestrap AP (2002)
Cardiac energetics in congestive heart failure - Response
Circulation, 105 (6), E44-E45

Sande JB, Sjaastad I, Hoen IB, Bokenes J, Tonnessen T, Holt E, Lunde PK, Christensen G (2002)
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity
Cardiovasc. Res., 53 (2), PII S0008-6363(01)00489-8-391

Sande JB, Sjaastad I, Hoen IB, Bøkenes J, Tønnessen T, Holt E, Lunde PK, Christensen G (2002)
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity
Cardiovasc Res, 53 (2), 382-91
PubMed 11827689

Sjaastad I, Bentzen JG, Semb SO, Ilebekk A, Sejersted OM (2002)
Reduced calcium tolerance in rat cardiomyocytes after myocardial infarction
Acta Physiol Scand, 175 (4), 261-9
PubMed 12167165

Sjaastad I, Bøkenes J, Swift F, Wasserstrom JA, Sejersted OM (2002)
Normal contractions triggered by I(Ca,L) in ventricular myocytes from rats with postinfarction CHF
Am J Physiol Heart Circ Physiol, 283 (3), H1225-36
PubMed 12181154

Publications 2001

Jóhannsson E, Lunde PK, Heddle C, Sjaastad I, Thomas MJ, Bergersen L, Halestrap AP, Blackstad TW, Ottersen OP, Sejersted OM (2001)
Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure
Circulation, 104 (6), 729-34
PubMed 11489783

Lunde PK, Sjaastad I, Schiøtz Thorud HM, Sejersted OM (2001)
Skeletal muscle disorders in heart failure
Acta Physiol Scand, 171 (3), 277-94
PubMed 11412140

Publications 2000

Sjaastad I, Grund F, Ilebekk A (2000)
Effects on infarct size and on arrhythmias by controlling reflow after myocardial ischaemia in pigs
Acta Physiol Scand, 169 (3), 195-201
PubMed 10886034

Sjaastad I, Sejersted OM, Ilebekk A, Bjornerheim R (2000)
Echocardiographic criteria for detection of postinfarction congestive heart failure in rats
J Appl Physiol (1985), 89 (4), 1445-54
PubMed 11007581

Wasserstrom JA, Holt E, Sjaastad I, Lunde PK, Odegaard A, Sejersted OM (2000)
Altered E-C coupling in rat ventricular myocytes from failing hearts 6 wk after MI
Am J Physiol Heart Circ Physiol, 279 (2), H798-807
PubMed 10924080

Publications 1999

Holt E, Sjaastad I, Lunde PK, Christensen G, Sejersted OM (1999)
Thyroid hormone control of contraction and the Ca(2+)-ATPase/phospholamban complex in adult rat ventricular myocytes
J Mol Cell Cardiol, 31 (3), 645-56
PubMed 10198194