Tone Berge
Position: Post.doc., Research coordinator at the Research Unit for Neuroscience, MSc, PhD
Phone: +47 230 79027
Email:

Background:

Tone Berge has a Master and PhD degree in Biochemistry from the Institute of Biosciences, University of Oslo, where she studied the hematopoietic transcription factor c-Myb. She used in vitro techniques as well as yeast and mammalian cells to define the optimal DNA binding sites for c-Myb. At the Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, she has performed postdoctoral research on T cells signaling, studying the adapter protein TSAd, encoded by the SH2D2A gene. Her main task was to characterize SH2D2A-deficient mice.

Project/Research interest:

Tone Berges main focus is to perform functional follow-up of immune-related genes that have been identified as MS susceptibility genes through genome-wide approaches. Berge is currently the main supervisor of two PhD students  Pankaj Kumar Keshari and Anna Eriksson and two Master students, Fernanda Correio Kropf and Ingrid Mo, and co-supervisor of PhD student Ina Skaara Brorson.

Research interest:
• Autoimmunity
• Vitamin D and MS
• Molecular immunology
• T cell activation
• Transcriptional regulation

Methodology:
• Transfection of cell lines
• Isolation and cultivation of primary, human T cells
• Western blotting
• Flow cytometry
• Quantitative real-time PCR
• Vector design and sub-cloning

Previous students (as main supervisor):

PhD student Ingvild Sørum Leikfoss, thesis defense: 30.10.15 - Characterization of multiple sclerosis susceptibility genes, genetic and molecular studies in T cells.

Master student Anna Eriksson, master exam: 18.12.14 - Molecular characterization of C-type lectin like domain family 16A (CLEC16A) Master student Ina Skaara Brorson, master exam: 14.01.15 -  Vitamin D responsiveness of multiple sclerosis associated genes in CD4+ T cells

Previous students (as co supervisor):

PhD student Marte Wendel Gusatvsen (main supervisor Hanne F. Harbo), thesis defence: 13.12.15 - Genetic, clinical and environmental aspects of multiple sclerosis.

Medical student at the the Medical Faculty Research program for medical students (main supervisor Anne Spurkland): exam 26.11.14 - Cell polarity and immune defence: Characterization of SH2D2A-deficient mice.