Publications

Publications published since 1988 or in press by Guttorm Haraldsen

63 publications found

Publications 2013

1. Pollheimer J, Bodin J, Sundnes O, Edelmann RJ, Skånland SS, Sponheim J, Brox MJ, Sundlisaeter E, Loos T, Vatn M, Kasprzycka M, Wang J, Küchler AM, Taskén K, Haraldsen G, Hol J (2013)
   Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells
   Arterioscler Thromb Vasc Biol, 33 (2), e47-55
   PubMed 23162017

Publications 2012

1. Hol J, Otterdal K, Breland UM, Stang E, Pedersen TM, Hagelsteen K, Ranheim T, Kasprzycka M, Halvorsen B, Haraldsen G, Aukrust P (2012)
   Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies
   PLoS One, 7 (7), e40673
   PubMed 22815786
2. Sundlisaeter E, Edelmann RJ, Hol J, Sponheim J, Küchler AM, Weiss M, Udalova IA, Midwood KS, Kasprzycka M, Haraldsen G (2012)
   The alarmin IL-33 is a notch target in quiescent endothelial cells
   Am J Pathol, 181 (3), 1099-111
   PubMed 22809957

Publications 2011

1. Haabeth OA, Lorvik KB, Hammarström C, Donaldson IM, Haraldsen G, Bogen B, Corthay A (2011)
   Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
   Nat Commun, 2, 240
   PubMed 21407206
2. Pollheimer J, Haslinger P, Fock V, Prast J, Saleh L, Biadasiewicz K, Jetne-Edelmann R, Haraldsen G, Haider S, Hirtenlehner-Ferber K, Knöfler M (2011)
   Endostatin suppresses IGF-II-mediated signaling and invasion of human extravillous trophoblasts
   Endocrinology, 152 (11), 4431-42
   PubMed 21933871

Publications 2010

1. Hol J, Wilhelmsen L, Haraldsen G (2010)
   The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
   J Leukoc Biol, 87 (3), 501-8
   PubMed 20007247
2. Mikalsen B, Fosby B, Wang J, Hammarström C, Bjaerke H, Lundström M, Kasprzycka M, Scott H, Line PD, Haraldsen G (2010)
   Genome-wide transcription profile of endothelial cells after cardiac transplantation in the rat
   Am J Transplant, 10 (7), 1534-44
   PubMed 20642680
3. Norrmén C, Vandevelde W, Ny A, Saharinen P, Gentile M, Haraldsen G, Puolakkainen P, Lukanidin E, Dewerchin M, Alitalo K, Petrova TV (2010)
   Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity
   Blood, 115 (4), 906-9
   PubMed 19965622
4. Sponheim J, Pollheimer J, Olsen T, Balogh J, Hammarström C, Loos T, Kasprzycka M, Sørensen DR, Nilsen HR, Küchler AM, Vatn MH, Haraldsen G (2010)
   Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts
   Am J Pathol, 177 (6), 2804-15
   PubMed 21037074

Publications 2009

1. Etokebe GE, Küchler AM, Haraldsen G, Landin M, Osmundsen H, Dembic Z (2009)
   Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds
   Arch Oral Biol, 54 (11), 1002-7
   PubMed 19740458
2. Haraldsen G, Balogh J, Pollheimer J, Sponheim J, Küchler AM (2009)
   Interleukin-33 - cytokine of dual function or novel alarmin?
   Trends Immunol, 30 (5), 227-33
   PubMed 19359217
3. Hol J, Küchler AM, Johansen FE, Dalhus B, Haraldsen G, Oynebråten I (2009)
   Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodies
   J Biol Chem, 284 (35), 23532-9
   PubMed 19578117

Publications 2008

1. Breland UM, Halvorsen B, Hol J, Øie E, Paulsson-Berne G, Yndestad A, Smith C, Otterdal K, Hedin U, Waehre T, Sandberg WJ, Frøland SS, Haraldsen G, Gullestad L, Damås JK, Hansson GK, Aukrust P (2008)
   A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
   Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
   PubMed 18276907
2. Küchler AM, Pollheimer J, Balogh J, Sponheim J, Manley L, Sorensen DR, De Angelis PM, Scott H, Haraldsen G (2008)
   Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
   Am J Pathol, 173 (4), 1229-42
   PubMed 18787100
3. Saethre M, Schneider MK, Lambris JD, Magotti P, Haraldsen G, Seebach JD, Mollnes TE (2008)
   Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model
   J Immunol, 180 (9), 6346-53
   PubMed 18424758

Publications 2007

1. Skovseth DK, Küchler AM, Haraldsen G (2007)
   The HUVEC/Matrigel assay: an in vivo assay of human angiogenesis suitable for drug validation
   Methods Mol Biol, 360, 253-68
   PubMed 17172733

Publications 2006

1. Haraldsen G, Rot A (2006)
   Coy decoy with a new ploy: interceptor controls the levels of homeostatic chemokines
   Eur J Immunol, 36 (7), 1659-61
   PubMed 16791884
2. Saethre M, Lea T, Borgen MS, Fiane AE, Michaelsen TE, Thorsby E, Haraldsen G, Mollnes TE (2006)
   Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation
   Xenotransplantation, 13 (3), 215-23
   PubMed 16756564

Publications 2005

1. Baekkevold ES, Wurbel MA, Kivisäkk P, Wain CM, Power CA, Haraldsen G, Campbell JJ (2005)
   A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations
   J Exp Med, 201 (7), 1045-51
   PubMed 15795234
2. Carlsen HS, Haraldsen G, Brandtzaeg P, Baekkevold ES (2005)
   Disparate lymphoid chemokine expression in mice and men: no evidence of CCL21 synthesis by human high endothelial venules
   Blood, 106 (2), 444-6
   PubMed 15863780
3. Corthay A, Skovseth DK, Lundin KU, Røsjø E, Omholt H, Hofgaard PO, Haraldsen G, Bogen B (2005)
   Primary antitumor immune response mediated by CD4+ T cells
   Immunity, 22 (3), 371-83
   PubMed 15780993
4. Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland S, Aukrust P, Mollnes TE (2005)
   Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation
   Eur Heart J, 26 (16), 1660-5
   PubMed 15821010
5. Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
   Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
   J Immunol, 174 (3), 1657-63
   PubMed 15661929
6. Skovseth DK, Veuger MJ, Sorensen DR, De Angelis PM, Haraldsen G (2005)
   Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo
   Blood, 105 (3), 1044-51
   PubMed 15466935
7. Øynebråten I, Barois N, Hagelsteen K, Johansen FE, Bakke O, Haraldsen G (2005)
   Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol
   J Immunol, 175 (8), 5358-69
   PubMed 16210642

Publications 2004

1. Carlsen HS, Baekkevold ES, Morton HC, Haraldsen G, Brandtzaeg P (2004)
   Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis
   Blood, 104 (10), 3021-7
   PubMed 15284119
2. Lacorre DA, Baekkevold ES, Garrido I, Brandtzaeg P, Haraldsen G, Amalric F, Girard JP (2004)
   Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment
   Blood, 103 (11), 4164-72
   PubMed 14976058
3. Øynebråten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G (2004)
   Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments
   Blood, 104 (2), 314-20
   PubMed 15044249

Publications 2003

1. Baekkevold ES, Roussigné M, Yamanaka T, Johansen FE, Jahnsen FL, Amalric F, Brandtzaeg P, Erard M, Haraldsen G, Girard JP (2003)
   Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
   Am J Pathol, 163 (1), 69-79
   PubMed 12819012
2. Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO (2003)
   Endothelial cell diversity revealed by global expression profiling
   Proc Natl Acad Sci U S A, 100 (19), 10623-8
   PubMed 12963823

Publications 2002

1. Carlsen HS, Baekkevold ES, Johansen FE, Haraldsen G, Brandtzaeg P (2002)
   B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue
   Gut, 51 (3), 364-71
   PubMed 12171958
2. Farstad IN, Malavasi F, Haraldsen G, Huitfeldt HS, Brandtzaeg P (2002)
   CD38 is a marker of human lacteals
   Virchows Arch, 441 (6), 605-13
   PubMed 12461619
3. Saethre M, Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Platt JL, Mollnes TE (2002)
   Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies
   Xenotransplantation, 9 (5), 350-8
   PubMed 12199866
4. Skovseth DK, Yamanaka T, Brandtzaeg P, Butcher EC, Haraldsen G (2002)
   Vascular morphogenesis and differentiation after adoptive transfer of human endothelial cells to immunodeficient mice
   Am J Pathol, 160 (5), 1629-37
   PubMed 12000715

Publications 2001

1. Baekkevold ES, Yamanaka T, Palframan RT, Carlsen HS, Reinholt FP, von Andrian UH, Brandtzaeg P, Haraldsen G (2001)
   The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment
   J Exp Med, 193 (9), 1105-12
   PubMed 11342595
2. Sølvik UO, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Mollnes TE (2001)
   C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells
   Transplant Proc, 33 (1-2), 789-90
   PubMed 11267073
3. Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE (2001)
   Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated
   Transplantation, 72 (12), 1967-73
   PubMed 11773897

Publications 2000

1. Kunkel EJ, Campbell JJ, Haraldsen G, Pan J, Boisvert J, Roberts AI, Ebert EC, Vierra MA, Goodman SB, Genovese MC, Wardlaw AJ, Greenberg HB, Parker CM, Butcher EC, Andrew DP, Agace WW (2000)
   Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
   J Exp Med, 192 (5), 761-8
   PubMed 10974041
2. Sindre H, Haraldsen G, Beck S, Hestdal K, Kvale D, Brandtzaeg P, Degré M, Rollag H (2000)
   Human intestinal endothelium shows high susceptibility to cytomegalovirus and altered expression of adhesion molecules after infection
   Scand J Immunol, 51 (4), 354-60
   PubMed 10736107

Publications 1999

1. Baekkevold ES, Jahnsen FL, Johansen FE, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G (1999)
   Culture characterization of differentiated high endothelial venule cells from human tonsils
   Lab Invest, 79 (3), 327-36
   PubMed 10092069
2. Brandtzaeg P, Farstad IN, Haraldsen G (1999)
   Regional specialization in the mucosal immune system: primed cells do not always home along the same track
   Immunol Today, 20 (6), 267-77
   PubMed 10354552
3. Brandtzaeg P, Haraldsen G, Baekkevold ES, Jahnsen FL, Nilsen EM (1999)
   Microvascular endothelial cells and leukocyte emigration
   FALK SYMP, 110, 383-400
4. Brandtzaeg P, Haraldsen G, Helgeland L, Nilsen EM, Rugtveit J (1999)
   New insights into the immunopathology of human inflammatory bowel disease
   Drugs Today, 35 A, 33-70
5. Campbell JJ, Haraldsen G, Pan J, Rottman J, Qin S, Ponath P, Andrew DP, Warnke R, Ruffing N, Kassam N, Wu L, Butcher EC (1999)
   The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
   Nature, 400 (6746), 776-80
   PubMed 10466728
6. Girard JP, Baekkevold ES, Yamanaka T, Haraldsen G, Brandtzaeg P, Amalric F (1999)
   Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridization
   Am J Pathol, 155 (6), 2043-55
   PubMed 10595934

Publications 1998

1. Brandtzaeg F, Farstad IN, Haraldsen G, Jahnsen FL (1998)
   Cellular and molecular mechanisms for induction of mucosal immunity
   Dev. Biols, 92, 93-108
2. Brandtzaeg P, Farstad IN, Haraldsen G, Jahnsen FL (1998)
   Cellular and molecular mechanisms for induction of mucosal immunity
   Dev Biol Stand, 92, 93-108
   PubMed 9554262
3. Haraldsen G, Sollid LM, Bakke O, Farstad IN, Kvale D, Molberg, Norstein J, Stang E, Brandtzaeg P (1998)
   Major histocompatibility complex class II-dependent antigen presentation by human intestinal endothelial cells
   Gastroenterology, 114 (4), 649-56
   PubMed 9516385
4. Nilsen EM, Johansen FE, Jahnsen FL, Lundin KE, Scholz T, Brandtzaeg P, Haraldsen G (1998)
   Cytokine profiles of cultured microvascular endothelial cells from the human intestine
   Gut, 42 (5), 635-42
   PubMed 9659156
5. Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P, Haraldsen G (1998)
   Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
   J Exp Med, 188 (9), 1751-6
   PubMed 9802986

Publications 1997

1. Brandtzaeg P, Berstad AE, Farstad IN, Haraldsen G, Helgeland L, Jahnsen FL, Johansen FE, Natvig IB, Nilsen EM, Rugtveit J (1997)
   Mucosal immunity--a major adaptive defence mechanism
   Behring Inst Mitt (98), 1-23
   PubMed 9382729
2. Brandtzaeg P, Haraldsen G, Rugtveit J (1997)
   Immunopathological mechanisms in inflammatory bowel disease
   FALK SYMP, 91, 15-51
3. Brandtzaeg P, Haraldsen G, Rugtveit J (1997)
   Immunopathology of human inflammatory bowel disease (vol 18, pg 555, 1997)
   Springer Semin. Immunopathol., 19 (2), 269
4. Brandtzaeg P, Haraldsen G, Rugtveit J (1997)
   Immunopathology of human inflammatory bowel disease
   Springer Semin Immunopathol, 18 (4), 555-89
   PubMed 9144870
5. Brandtzaeg P, Jahnsen FL, Farstad IN, Haraldsen G (1997)
   Mucosal immunology of the upper airways: an overview
   Ann N Y Acad Sci, 830, 1-18
   PubMed 9616663
6. Jahnsen FL, Brandtzaeg P, Haye R, Haraldsen G (1997)
   Expression of functional VCAM-1 by cultured nasal polyp-derived microvascular endothelium
   Am J Pathol, 150 (6), 2113-23
   PubMed 9176402
7. Natvig IB, Johansen FE, Nordeng TW, Haraldsen G, Brandtzaeg P (1997)
   Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis
   J Immunol, 159 (9), 4330-40
   PubMed 9379029

Publications 1996

1. Haraldsen G, Kvale D, Lien B, Farstad IN, Brandtzaeg P (1996)
   Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells
   J Immunol, 156 (7), 2558-65
   PubMed 8786319

Publications 1995

1. Haraldsen G, Rugtveit J, Kvale D, Scholz T, Muller WA, Hovig T, Brandtzaeg P (1995)
   Isolation and longterm culture of human intestinal microvascular endothelial cells
   Gut, 37 (2), 225-34
   PubMed 7557573
2. Jahnsen FL, Haraldsen G, Aanesen JP, Haye R, Brandtzaeg P (1995)
   Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps
   Am J Respir Cell Mol Biol, 12 (6), 624-32
   PubMed 7539273
3. Rugtveit J, Haraldsen G, Høgåsen AK, Bakka A, Brandtzaeg P, Scott H (1995)
   Respiratory burst of intestinal macrophages in inflammatory bowel disease is mainly caused by CD14+L1+ monocyte derived cells
   Gut, 37 (3), 367-73
   PubMed 7590432

Publications 1994

1. Jahnsen FL, Haraldsen G, Rugtveit J, Halstensen TS, Brandtzaeg P (1994)
   Differential interference contrast microscopy combined with immunofluorescence: a new method to phenotype eosinophils in situ
   J Immunol Methods, 173 (1), 77-91
   PubMed 8034989

Publications 1988

1. Schubert W, Kontozis L, Sticker G, Schwan H, Haraldsen G, Jerusalem F (1988)
   Immunofluorescent evidence for presence of interleukin-1 in normal and diseased human skeletal muscle
   Muscle Nerve, 11 (8), 890-2
   PubMed 3050511