Publications

Publications published since 2000 from OUS - Department of Genetics

459 publications found

Publications 2014

  1. Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K (2014)
    Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity
    Cell Rep, 6 (3), 514-27
    PubMed 24462293
  2. Askautrud HA, Gjernes E, Gunnes G, Sletten M, Ross DT, Børresen-Dale AL, Iversen N, Tranulis MA, Frengen E (2014)
    Global gene expression analysis reveals a link between NDRG1 and vesicle transport
    PLoS One, 9 (1), e87268
    PubMed 24498060
  3. Bjaanaes MM, Halvorsen AR, Solberg S, Jørgensen L, Dragani TA, Galvan A, Colombo F, Anderlini M, Pastorino U, Kure E, Børresen-Dale AL, Brustugun OT, Helland A (2014)
    Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
    Int J Cancer, 135 (8), 1812-21
    PubMed 24599520
  4. Fannemel M, Barøy T, Holmgren A, Rødningen OK, Haugsand TM, Hansen B, Frengen E, Misceo D (2014)
    Haploinsufficiency of XPO1 and USP34 by a de novo 230 kb deletion in 2p15, in a patient with mild intellectual disability and cranio-facial dysmorphisms
    Eur J Med Genet, 57 (9), 513-9
    PubMed 24911659
  5. Fleischer T, Edvardsen H, Solvang HK, Daviaud C, Naume B, Børresen-Dale AL, Kristensen VN, Tost J (2014)
    Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients
    Int J Cancer, 134 (11), 2615-25
    PubMed 24395279
  6. Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis M, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
    Genome-wide DNA methylation profiles in progression to
    Genome Biol, 15 (8), 435 (in press)
    PubMed 25146004
  7. Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE et al. (2014)
    Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
    Nat Commun, 4, 4999
    PubMed 25248036
  8. Grinde MT, Skrbo N, Moestue SA, Rødland EA, Borgan E, Kristian A, Sitter B, Bathen TF, Børresen-Dale AL, Mælandsmo GM, Engebraaten O, Sørlie T, Marangoni E, Gribbestad IS (2014)
    Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
    Breast Cancer Res, 16 (1), R5
    PubMed 24447408
  9. Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
    Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
    Int J Cancer, 135 (9), 2085-95
    PubMed 24658971
  10. Johnson N, Dudbridge F, Orr N, Gibson L, Jones ME, Schoemaker MJ, Folkerd EJ, Haynes BP, Hopper JL, Southey MC, Dite GS, Apicella C, Schmidt MK, Broeks A, Van T Veer LJ, Atsma F, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Ekici AB, Renner SP, Sawyer E, Tomlinson I, Kerin M et al. (2014)
    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study
    Breast Cancer Res, 16 (3), R51 (in press)
    PubMed 24887515
  11. Kjersem JB, Skovlund E, Ikdahl T, Guren T, Kersten C, Dalsgaard AM, Yilmaz MK, Fokstuen T, Tveit KM, Kure EH (2014)
    FCGR2A and FCGR3A polymorphisms and clinical outcome in metastatic colorectal cancer patients treated with first-line 5-fluorouracil/folinic acid and oxaliplatin +/- cetuximab
    BMC Cancer, 14, 340
    PubMed 24884501
  12. Kristensen VN, Lingjærde OC, Russnes HG, Vollan HK, Frigessi A, Børresen-Dale AL (2014)
    Principles and methods of integrative genomic analyses in cancer
    Nat Rev Cancer, 14 (5), 299-313
    PubMed 24759209
  13. Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, Michailidou K, Dennis J, Bolla MK, Wang Q, Van 't Veer LJ, Cornelissen S, Rutgers E, Southey MC, Apicella C, Dite GS, Hopper JL, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Blomqvist C, Muranen TA, Aittomäki K, Lindblom A et al. (2014)
    2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
    Nat Commun, 5, 4051
    PubMed 24937182
  14. Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N et al. (2014)
    Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
    Hum Mol Genet (in press)
    PubMed 25168388
  15. Norum JH, Andersen K, Sørlie T (2014)
    Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
    Br J Surg, 101 (8), 925-38
    PubMed 24849143
  16. Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
    Br J Cancer, 110 (8), 2072-80
    PubMed 24577056
  17. Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, Guénel P, Meindl A, Darabi H et al. (2014)
    Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
    Hum Mol Genet (in press)
    PubMed 24927736
  18. Quigley D (2014)
    RNA-seq permits a closer look at normal skin and psoriasis gene networks
    J Invest Dermatol, 134 (7), 1789-91
    PubMed 24924757
  19. Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO (2014)
    Long Non-Coding RNAs Differentially Expressed between Normal versus Primary Breast Tumor Tissues Disclose Converse Changes to Breast Cancer-Related Protein-Coding Genes
    PLoS One, 9 (9), e106076
    PubMed 25264628
  20. Saldova R, Asadi Shehni A, Haakensen VD, Steinfeld I, Hilliard M, Kifer I, Helland A, Yakhini Z, Børresen-Dale AL, Rudd PM (2014)
    Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC
    J Proteome Res, 13 (5), 2314-27
    PubMed 24669823
  21. Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hopper JL, Provenzano E et al. (2014)
    Genetic predisposition to in situ and invasive lobular carcinoma of the breast
    PLoS Genet, 10 (4), e1004285
    PubMed 24743323
  22. Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, Quigley DA, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Langerød A (2014)
    TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
    Clin Cancer Res, 20 (13), 3569-80
    PubMed 24803582
  23. Sternemalm J, Russnes HG, Zhao X, Risberg B, Nord S, Caldas C, Børresen-Dale AL, Stokke T, Patzke S (2014)
    Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
    Br J Cancer, 111 (2), 326-38
    PubMed 24901235
  24. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
    Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
    Methods Mol Biol, 1105, 315-24
    PubMed 24623239
  25. Tarpgaard LS, Guren TK, Glimelius B, Christensen IJ, Pfeiffer P, Kure EH, Sorbye H, Ikdahl T, Yilmaz M, Johansen JS, Tveit KM (2014)
    Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study
    PLoS One, 9 (2), e87746
    PubMed 24498368
  26. Tramm T, Kyndi M, Myhre S, Nord S, Alsner J, Sørensen FB, Sørlie T, Overgaard J (2014)
    Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer
    Acta Oncol, 1-10 (in press)
    PubMed 24957550
  27. Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J (2014)
    Development and Validation of a Gene Profile Predicting Benefit of Postmastectomy Radiotherapy in Patients with High-Risk Breast Cancer: A Study of Gene Expression in the DBCG82bc Cohort
    Clin Cancer Res (in press)
    PubMed 25149560
  28. Trinh A, Rye IH, Almendro V, Helland A, Russnes HG, Markowetz F (2014)
    GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images
    Genome Biol, 15 (8), 442 (in press)
    PubMed 25168174
  29. Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Marshall J, Wedge DC, Teague JW, Butler AP et al. (2014)
    Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
    Science, 345 (6196), 1251343
    PubMed 25082706
  30. Vogel LK, Sæbø M, Høyer H, Kopp TI, Vogel U, Godiksen S, Frenzel FB, Hamfjord J, Bowitz-Lothe IM, Johnson E, Kure EH, Andersen V (2014)
    Intestinal PTGS2 mRNA Levels, PTGS2 Gene Polymorphisms, and Colorectal Carcinogenesis
    PLoS One, 9 (8), e105254
    PubMed 25166592
  31. Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN, METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C (2014)
    A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
    Mol Oncol (in press)
    PubMed 25169931
  32. Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E (2014)
    Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
    PLoS One, 9 (8), e103873
    PubMed 25148029
  33. Yamamoto S, Wu Z, Russnes HG, Takagi S, Peluffo G, Vaske C, Zhao X, Moen Vollan HK, Maruyama R, Ekram MB, Sun H, Kim JH, Carver K, Zucca M, Feng J, Almendro V, Bessarabova M, Rueda OM, Nikolsky Y, Caldas C, Liu XS, Polyak K (2014)
    JARID1B is a luminal lineage-driving oncogene in breast cancer
    Cancer Cell, 25 (6), 762-77
    PubMed 24937458
  34. Zhao X, Rødland EA, Sørlie T, Vollan HK, Russnes HG, Kristensen VN, Lingjærde OC, Børresen-Dale AL (2014)
    Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
    BMC Cancer, 14, 211
    PubMed 24645668
  35. Zink AM, Wohlleber E, Engels H, Rødningen OK, Ravn K, Heilmann S, Rehnitz J, Katzorke N, Kraus C, Blichfeldt S, Hoffmann P, Reutter H, Brockschmidt FF, Kreiß-Nachtsheim M, Vogt PH, Prescott TE, Tümer Z, Lee JA (2014)
    Microdeletions including FMR1 in three female patients with intellectual disability - further delineation of the phenotype and expression studies
    Mol Syndromol, 5 (2), 65-75
    PubMed 24715853

Publications 2013

  1. Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
    Signatures of mutational processes in human cancer
    Nature, 500 (7463), 415-21
    PubMed 23945592
  2. Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
    Correction: Low ABCB1 Gene Expression Is an Early Event in Colorectal Carcinogenesis
    PLoS One, 8 (9)
    PubMed 24137504
  3. Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
    Low ABCB1 gene expression is an early event in colorectal carcinogenesis
    PLoS One, 8 (8), e72119
    PubMed 23977225
  4. Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
    Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
    Genome Biol, 14 (11), R126
    PubMed 24257477
  5. Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
    Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
    PLoS One, 8 (1), e53014
    PubMed 23382830
  6. Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
    High levels of genomic aberrations in serous ovarian cancers are associated with better survival
    PLoS One, 8 (1), e54356
    PubMed 23372714
  7. Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
    Improving breast cancer survival analysis through competition-based multidimensional modeling
    PLoS Comput Biol, 9 (5), e1003047
    PubMed 23671412
  8. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
    Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
    Nat Genet, 45 (4), 371-84, 384e1-2
    PubMed 23535731
  9. Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
    Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
    Cell Stem Cell, 13 (1), 117-30
    PubMed 23770079
  10. Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
    SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
    Int J Radiat Oncol Biol Phys, 86 (4), 791-9
    PubMed 23597419
  11. Enerly E, Olofsson C, Nygård M (2013)
    Monitoring human papillomavirus prevalence in urine samples: a review
    Clin Epidemiol, 5, 67-79
    PubMed 23516174
  12. Engebraaten O, Vollan HK, Børresen-Dale AL (2013)
    Triple-negative breast cancer and the need for new therapeutic targets
    Am J Pathol, 183 (4), 1064-74
    PubMed 23920327
  13. French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
    Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
    Am J Hum Genet, 92 (4), 489-503
    PubMed 23540573
  14. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
    Genome-wide association studies identify four ER negative-specific breast cancer risk loci
    Nat Genet, 45 (4), 392-8, 398e1-2
    PubMed 23535733
  15. Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
    Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
    Cancer Res, 73 (21), 6424-34
    PubMed 24030979
  16. Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
    Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
    PLoS One, 8 (11), e78241
    PubMed 24244297
  17. Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
    High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
    PLoS One, 8 (10), e77232
    PubMed 24194875
  18. Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
    AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
    Breast Cancer Res Treat, 141 (3), 397-408
    PubMed 24091768
  19. Katika MR, Hurtado A (2013)
    A functional link between FOXA1 and breast cancer SNPs
    Breast Cancer Res, 15 (1), 303
    PubMed 23427833
  20. Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
    Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
    Mol Oncol, 8 (1), 59-67
    PubMed 24119443
  21. Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
    Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
    BMC Cancer, 13, 456
    PubMed 24093668
  22. Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
    Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
    Genomics, 102 (4), 278-87
    PubMed 23880221
  23. Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
    High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
    Mol Oncol, 8 (1), 93-104
    PubMed 24148764
  24. Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
    Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
    J Med Genet, 50 (10), 666-73
    PubMed 23825393
  25. Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Mælandsmo GM, Engebraaten O (2013)
    Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
    Clin Cancer Res, 20 (2), 404-12
    PubMed 24192926
  26. Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
    Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
    Breast Cancer Res Treat, 143 (1), 189-201
    PubMed 24305980
  27. Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
    Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
    Sci Transl Med, 5 (181), 181re1
    PubMed 23596205
  28. Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
    Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
    Am J Hum Genet, 93 (6), 1046-60
    PubMed 24290378
  29. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
    Large-scale genotyping identifies 41 new loci associated with breast cancer risk
    Nat Genet, 45 (4), 353-61, 361e1-2
    PubMed 23535729
  30. Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
    A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
    Hum Mol Genet, 23 (7), 1934-46
    PubMed 24242184
  31. Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
    Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
    Mol Oncol, 7 (3), 704-18
    PubMed 23562353
  32. Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
    Next-generation sequencing of disseminated tumor cells
    Front Oncol, 3, 320
    PubMed 24427740
  33. Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
    Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
    Pancreatology, 13 (2), 180-5
    PubMed 23561977
  34. Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
    Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
    PLoS One, 8 (5), e62153
    PubMed 23671585
  35. Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
    Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
    Carcinogenesis, 35 (5), 1012-9
    PubMed 24325915
  36. Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
    The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
    Mol Oncol, 8 (2), 273-84
    PubMed 24388359
  37. Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
    Two Distinct Categories of Focal Deletions in Cancer Genomes
    PLoS One, 8 (6), e66264
    PubMed 23805207
  38. Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
    Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
    ISRN Oncol, 2013, 924971
    PubMed 23533813
  39. Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    PubMed 23942067
  40. Rud AK, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
    Osteopontin is a prognostic biomarker in non-small cell lung cancer
    BMC Cancer, 13, 540
    PubMed 24215488
  41. Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
    Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
    Carcinogenesis, 35 (1), 76-85
    PubMed 24104550
  42. Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
    Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
    Virchows Arch, 463 (6), 775-86
    PubMed 24100522
  43. Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
    Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
    BMC Cancer, 13, 512
    PubMed 24171825

Publications 2012

  1. Bilal E, Vassallo K, Toppmeyer D, Barnard N, Rye IH, Almendro V, Russnes H, Børresen-Dale AL, Levine AJ, Bhanot G, Ganesan S (2012)
    Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers
    PLoS One, 7 (6), e38575
    PubMed 22719901
  2. Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T (2012)
    Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
    Mol Oncol, 7 (1), 130-42
    PubMed 23142657
  3. Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S, METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L et al. (2012)
    The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    Nature, 486 (7403), 346-52
    PubMed 22522925
  4. Engebraaten O, Edvardsen H, Løkkevik E, Naume B, Kristensen V, Ottestad L, Natarajan V (2012)
    Gefitinib in Combination with Weekly Docetaxel in Patients with Metastatic Breast Cancer Caused Unexpected Toxicity: Results from a Randomized Phase II Clinical Trial
    ISRN Oncol, 2012, 176789
    PubMed 22666610
  5. Fiorito E, Katika MR, Hurtado A (2012)
    Cooperating transcription factors mediate the function of estrogen receptor
    Chromosoma, 122 (1-2), 1-12
    PubMed 23192763
  6. Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C (2012)
    Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
    Cell, 148 (1-2), 244-58
    PubMed 22265415
  7. Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang Q, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Hall P, Czene K et al. (2012)
    Genome-wide association analysis identifies three new breast cancer susceptibility loci
    Nat Genet, 44 (3), 312-8
    PubMed 22267197
  8. Gilfillan S, Fiorito E, Hurtado A (2012)
    Functional genomic methods to study estrogen receptor activity
    J Mammary Gland Biol Neoplasia, 17 (2), 147-53
    PubMed 22588661
  9. Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Sorlie T, Sotiriou C, Turner N, Van de Vijver M, Viale G, Loi S, Reis-Filho JS (2012)
    Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement
    Ann Oncol, 23 (12), 2997-3006
    PubMed 23166150
  10. Hamfjord J, Stangeland AM, Hughes T, Skrede ML, Tveit KM, Ikdahl T, Kure EH (2012)
    Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing
    PLoS One, 7 (4), e34150
    PubMed 22529906
  11. Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FB, Bueno-de-Mesquita HB, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Fasching PA, Hein A, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Sawyer E, Tomlinson I, Kerin M et al. (2012)
    Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)
    PLoS One, 7 (8), e42380
    PubMed 22879957
  12. Joshi H, Bhanot G, Børresen-Dale AL, Kristensen V (2012)
    Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
    Br J Cancer, 107 (10), 1722-8
    PubMed 23079576
  13. Joshi H, Nord SH, Frigessi A, Børresen-Dale AL, Kristensen VN (2012)
    Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
    BMC Genomics, 13, 199
    PubMed 22616941
  14. Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW (2012)
    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
    Proc Natl Acad Sci U S A, 109 (16), 6124-9
    PubMed 22454501
  15. Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH (2012)
    Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
    BMC Cancer, 12, 534
    PubMed 23167843
  16. Kure EH, Hamfjord J, Stangeland AM, Tveit KM, Ikdahl T (2012)
    KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem
    Expert Rev Mol Diagn, 12 (4), 327-8
    PubMed 22616697
  17. Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C, Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JI, Benítez J, Hamann U, Ko YD, Brüning T, GENICA Network et al. (2012)
    11q13 is a susceptibility locus for hormone receptor positive breast cancer
    Hum Mutat, 33 (7), 1123-32
    PubMed 22461340
  18. Mathiesen RR, Borgen E, Renolen A, Løkkevik E, Nesland JM, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Kvalheim G, Lønning PE, Naume B (2012)
    Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
    Breast Cancer Res, 14 (4), R117
    PubMed 22889108
  19. Natrajan R, Mackay A, Wilkerson PM, Lambros MB, Wetterskog D, Arnedos M, Shiu KK, Geyer FC, Langerød A, Kreike B, Reyal F, Horlings HM, van de Vijver MJ, Palacios J, Weigelt B, Reis-Filho JS (2012)
    Functional characterization of the 19q12 amplicon in grade III breast cancers
    Breast Cancer Res, 14 (2), R53
    PubMed 22433433
  20. Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD, Raine K, Jones D, Hinton J, Marshall J, Stebbings LA, Menzies A, Martin S, Leung K, Chen L, Leroy C, Ramakrishna M, Rance R, Lau KW, Mudie LJ, Varela I, McBride DJ, Bignell GR, Cooke SL, Shlien A, Gamble J et al. (2012)
    Mutational processes molding the genomes of 21 breast cancers
    Cell, 149 (5), 979-93
    PubMed 22608084
  21. Nik-Zainal S, Van Loo P, Wedge DC, Alexandrov LB, Greenman CD, Lau KW, Raine K, Jones D, Marshall J, Ramakrishna M, Shlien A, Cooke SL, Hinton J, Menzies A, Stebbings LA, Leroy C, Jia M, Rance R, Mudie LJ, Gamble SJ, Stephens PJ, McLaren S, Tarpey PS, Papaemmanuil E, Davies HR et al. (2012)
    The life history of 21 breast cancers
    Cell, 149 (5), 994-1007
    PubMed 22608083
  22. Nilsen G, Liestøl K, Van Loo P, Moen Vollan HK, Eide MB, Rueda OM, Chin SF, Russell R, Baumbusch LO, Caldas C, Børresen-Dale AL, Lingjaerde OC (2012)
    Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
    BMC Genomics, 13, 591
    PubMed 23442169
  23. Otto B, Gruner K, Heinlein C, Wegwitz F, Nollau P, Ylstra B, Pantel K, Schumacher U, Baumbusch LO, Martin-Subero JI, Siebert R, Wagener C, Streichert T, Deppert W, Tolstonog GV (2012)
    Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression
    Int J Cancer, 132 (6), 1300-10
    PubMed 22907219
  24. Ree AH, Kristensen AT, Saelen MG, de Wijn R, Edvardsen H, Jovanovic J, Abrahamsen TW, Dueland S, Flatmark K (2012)
    Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer
    PLoS One, 7 (11), e50806
    PubMed 23226389
  25. Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR (2012)
    Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes
    ISRN Oncol, 2012, 450267
    PubMed 23227362
  26. Sahlberg KK, Hongisto V, Edgren H, Mäkelä R, Hellström K, Due EU, Moen Vollan HK, Sahlberg N, Wolf M, Børresen-Dale AL, Perälä M, Kallioniemi O (2012)
    The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells
    Mol Oncol, 7 (3), 392-401
    PubMed 23253899
  27. Stavnes HT, Nymoen DA, Langerød A, Holth A, Børresen Dale AL, Davidson B (2012)
    AZGP1 and SPDEF mRNA expression differentiates breast carcinoma from ovarian serous carcinoma
    Virchows Arch, 462 (2), 163-73
    PubMed 23242172
  28. Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A et al. (2012)
    The landscape of cancer genes and mutational processes in breast cancer
    Nature, 486 (7403), 400-4
    PubMed 22722201
  29. Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, GENICA Network, Ko YD, Fischer HP, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C et al. (2012)
    19p13.1 is a triple-negative-specific breast cancer susceptibility locus
    Cancer Res, 72 (7), 1795-803
    PubMed 22331459
  30. Synnestvedt M, Borgen E, Russnes HG, Kumar NT, Schlichting E, Giercksky KE, Kåresen R, Nesland JM, Naume B (2012)
    Combined analysis of vascular invasion, grade, HER2 and Ki67 expression identifies early breast cancer patients with questionable benefit of systemic adjuvant therapy
    Acta Oncol, 52 (1), 91-101
    PubMed 22934555
  31. Tveit KM, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, Sigurdsson F, Kure E, Ikdahl T, Skovlund E, Fokstuen T, Hansen F, Hofsli E, Birkemeyer E, Johnsson A, Starkhammar H, Yilmaz MK, Keldsen N, Erdal AB, Dajani O, Dahl O, Christoffersen T (2012)
    Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study
    J Clin Oncol, 30 (15), 1755-62
    PubMed 22473155
  32. Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C, Odefrey F, Gierach GL, Jud SM, Heusinger K, Beckmann MW, Pollan M, Fernández-Navarro P, Gonzalez-Neira A, Benitez J, van Gils CH, Lokate M, Onland-Moret NC, Peeters PH, Brown J, Leyland J, Varghese JS, Easton DF et al. (2012)
    Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk
    Cancer Epidemiol Biomarkers Prev, 21 (7), 1156-66
    PubMed 22454379
  33. Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adamek J, Edvardsen H, Kristensen VN, Gut I, Soucek P (2012)
    Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis
    Clin Chem Lab Med, 50 (11), 1999-2007
    PubMed 23093106
  34. Weischer M, Nordestgaard BG, Pharoah P, Bolla MK, Nevanlinna H, Van't Veer LJ, Garcia-Closas M, Hopper JL, Hall P, Andrulis IL, Devilee P, Fasching PA, Anton-Culver H, Lambrechts D, Hooning M, Cox A, Giles GG, Burwinkel B, Lindblom A, Couch FJ, Mannermaa A, Grenaker Alnæs G, John EM, Dörk T, Flyger H et al. (2012)
    CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer
    J Clin Oncol, 30 (35), 4308-16
    PubMed 23109706

Publications 2011

  1. Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL (2011)
    Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
    Mol Oncol, 5 (6), 564-76
    PubMed 21917534
  2. Borge KS, Børresen-Dale AL, Lingaas F (2011)
    Identification of genetic variation in 11 candidate genes of canine mammary tumour
    Vet Comp Oncol, 9 (4), 241-50
    PubMed 22077404
  3. Bornholdt J, Friis S, Godiksen S, Poulsen SS, Santoni-Rugiu E, Bisgaard HC, Lothe IM, Ikdahl T, Tveit KM, Johnson E, Kure EH, Vogel LK (2011)
    The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
    BMC Cancer, 11, 65
    PubMed 21310043
  4. Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C et al. (2011)
    Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
    Hum Mol Genet, 20 (16), 3289-303
    PubMed 21596841
  5. Edgren H, Murumagi A, Kangaspeska S, Nicorici D, Hongisto V, Kleivi K, Rye IH, Nyberg S, Wolf M, Borresen-Dale AL, Kallioniemi O (2011)
    Identification of fusion genes in breast cancer by paired-end RNA-sequencing
    Genome Biol, 12 (1), R6
    PubMed 21247443
  6. Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, Rønneberg JA, Johnsen H, Navon R, Rødland E, Mäkelä R, Naume B, Perälä M, Kallioniemi O, Kristensen VN, Yakhini Z, Børresen-Dale AL (2011)
    miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
    PLoS One, 6 (2), e16915
    PubMed 21364938
  7. Gonzalez-Angulo AM, Hennessy BT, Meric-Bernstam F, Sahin A, Liu W, Ju Z, Carey MS, Myhre S, Speers C, Deng L, Broaddus R, Lluch A, Aparicio S, Brown P, Pusztai L, Symmans WF, Alsner J, Overgaard J, Borresen-Dale AL, Hortobagyi GN, Coombes KR, Mills GB (2011)
    Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer
    Clin Proteomics, 8 (1), 11
    PubMed 21906370
  8. Grinde MT, Moestue SA, Borgan E, Risa Ø, Engebraaten O, Gribbestad IS (2011)
    13C high-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns
    NMR Biomed, 24 (10), 1243-52
    PubMed 21462378
  9. Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD (2011)
    Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
    PLoS One, 6 (4), e18064
    PubMed 21533284
  10. Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
    EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
    J Thorac Oncol, 6 (5), 947-50
    PubMed 21623266
  11. Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY (2011)
    Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    Nat Genet, 43 (7), 621-9
    PubMed 21642992
  12. Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
    Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
    BMC Cancer, 11, 332
    PubMed 21812955
  13. Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
    Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
    BMC Med Genomics, 4, 77
    PubMed 22044755
  14. Kaveh F, Edvardsen H, Børresen-Dale AL, N Kristensen V, Solvang HK (2011)
    Allele-specific disparity in breast cancer
    BMC Med Genomics, 4, 85
    PubMed 22188678
  15. Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS et al. (2011)
    The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
    Cancer Cell, 19 (2), 273-82
    PubMed 21316605
  16. Kristensen VN (2011)
    Divide and conquer: the genetic basis of molecular subclassification of breast cancer
    EMBO Mol Med, 3 (4), 183-5
    PubMed 21394915
  17. Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
    Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
    Proc Natl Acad Sci U S A, 109 (8), 2802-7
    PubMed 21908711
  18. Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA (2011)
    ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
    Front Biosci (Elite Ed), 3, 1443-55
    PubMed 21622148
  19. Mathiesen RR, Fjelldal R, Liestøl K, Due EU, Geigl JB, Riethdorf S, Borgen E, Rye IH, Schneider IJ, Obenauf AC, Mauermann O, Nilsen G, Christian Lingjaerde O, Børresen-Dale AL, Pantel K, Speicher MR, Naume B, Baumbusch LO (2011)
    High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer
    Int J Cancer, 131 (4), E405-15
    PubMed 21935921
  20. Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Arias Pérez JI, Benítez J, Dörk T, Schürmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliot G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC et al. (2011)
    Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
    Cancer Epidemiol Biomarkers Prev, 20 (10), 2222-31
    PubMed 21795498
  21. Molloy TJ, Bosma AJ, Baumbusch LO, Synnestvedt M, Borgen E, Russnes HG, Schlichting E, van't Veer LJ, Naume B (2011)
    The prognostic significance of tumour cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients
    Breast Cancer Res, 13 (3), R61
    PubMed 21672237
  22. Møller P, Clark N, Mæhle L (2011)
    A SImplified method for Segregation Analysis (SISA) to determine penetrance and expression of a genetic variant in a family
    Hum Mutat, 32 (5), 568-71
    PubMed 21309035
  23. Perou CM, Børresen-Dale AL (2011)
    Systems biology and genomics of breast cancer
    Cold Spring Harb Perspect Biol, 3 (2)
    PubMed 21047916
  24. Reinertsen KV, Grenaker Alnæs GI, Landmark-Høyvik H, Loge JH, Wist E, Kristensen VN, Fosså SD, Edvardsen H (2011)
    Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway
    Brain Behav Immun, 25 (7), 1376-83
    PubMed 21496483
  25. Russnes HG, Kuligina ESh, Suspitsin EN, Voskresenskiy DA, Jordanova ES, Cornelisse CJ, Borresen-Dale AL, Imyanitov EN (2011)
    Paired distribution of molecular subtypes in bilateral breast carcinomas
    Cancer Genet, 204 (2), 96-102
    PubMed 21504707
  26. Russnes HG, Navin N, Hicks J, Borresen-Dale AL (2011)
    Insight into the heterogeneity of breast cancer through next-generation sequencing
    J Clin Invest, 121 (10), 3810-8
    PubMed 21965338
  27. Sagerup CM, Småstuen M, Johannesen TB, Helland A, Brustugun OT (2011)
    Increasing age and carcinoma not otherwise specified: a 20-year population study of 40,118 lung cancer patients
    J Thorac Oncol, 7 (1), 57-63
    PubMed 21900838
  28. Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
    Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
    BMC Bioinformatics, 12, 197
    PubMed 21609452
  29. Sørlie T (2011)
    How to personalise treatment in early breast cancer
    Eur J Cancer, 47 Suppl 3, S310-1
    PubMed 21943994
  30. van den Broek AJ, Broeks A, Horlings HM, Canisius SV, Braaf LM, Langerød A, Van't Veer LJ, Schmidt MK (2011)
    Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups
    Breast Cancer Res Treat, 130 (2), 599-608
    PubMed 21667122
  31. Van Loo P, Nilsen G, Nordgard SH, Vollan HK, Børresen-Dale AL, Kristensen VN, Lingjærde OC (2011)
    Analyzing cancer samples with SNP arrays
    Methods Mol Biol, 802, 57-72
    PubMed 22130873
  32. Vollan HK, Caldas C (2011)
    The breast cancer genome--a key for better oncology
    BMC Cancer, 11, 501
    PubMed 22128823
  33. Weigman VJ, Chao HH, Shabalin AA, He X, Parker JS, Nordgard SH, Grushko T, Huo D, Nwachukwu C, Nobel A, Kristensen VN, Børresen-Dale AL, Olopade OI, Perou CM (2011)
    Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Breast Cancer Res Treat, 133 (3), 865-80
    PubMed 22048815
  34. Westbury CB, Sahlberg KK, Borresen-Dale AL, Isacke CM, Yarnold JR (2011)
    Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients
    Radiat Oncol, 6, 42
    PubMed 21521514
  35. Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
    Combining gene signatures improves prediction of breast cancer survival
    PLoS One, 6 (3), e17845
    PubMed 21423775

Publications 2010

  1. Anaganti S, Fernández-Cuesta L, Langerød A, Hainaut P, Olivier M (2010)
    p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
    Cancer Lett, 300 (2), 215-24
    PubMed 21071137
  2. Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y (2010)
    EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors
    Sci Signal, 3 (124), ra43
    PubMed 20516477
  3. Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE (2010)
    Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
    Mol Cancer, 9, 173
    PubMed 20594292
  4. Bernstein JL, Haile RW, Stovall M, Boice JD, Shore RE, Langholz B, Thomas DC, Bernstein L, Lynch CF, Olsen JH, Malone KE, Mellemkjaer L, Borresen-Dale AL, Rosenstein BS, Teraoka SN, Diep AT, Smith SA, Capanu M, Reiner AS, Liang X, Gatti RA, Concannon P, WECARE Study Collaborative Group (2010)
    Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study
    J Natl Cancer Inst, 102 (7), 475-83
    PubMed 20305132
  5. Biong M, Gram IT, Brill I, Johansen F, Solvang HK, Alnaes GI, Fagerheim T, Bremnes Y, Chanock SJ, Burdett L, Yeager M, Ursin G, Kristensen VN (2010)
    Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
    BMC Med Genomics, 3, 9
    PubMed 20302654
  6. Borg A, Haile RW, Malone KE, Capanu M, Diep A, Törngren T, Teraoka S, Begg CB, Thomas DC, Concannon P, Mellemkjaer L, Bernstein L, Tellhed L, Xue S, Olson ER, Liang X, Dolle J, Børresen-Dale AL, Bernstein JL (2010)
    Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study
    Hum Mutat, 31 (3), E1200-40
    PubMed 20104584
  7. Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS (2010)
    Merging transcriptomics and metabolomics--advances in breast cancer profiling
    BMC Cancer, 10, 628
    PubMed 21080935
  8. Borresen-Dale AL (2010)
    Europe's largest Member Association for Cancer Research
    Period. Biol., 112 (4), 483-485
  9. Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
    On the molecular biology of breast cancer
    Mol Oncol, 4 (3), 171-3
    PubMed 20483673
  10. de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L (2010)
    Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
    Am J Pathol, 176 (3), 1229-40
    PubMed 20133812
  11. Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J (2010)
    DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
    Mol Cancer, 9, 68
    PubMed 20338046
  12. Dumeaux V, Olsen KS, Nuel G, Paulssen RH, Børresen-Dale AL, Lund E (2010)
    Deciphering normal blood gene expression variation--The NOWAC postgenome study
    PLoS Genet, 6 (3), e1000873
    PubMed 20300640
  13. Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
    SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
    Pharmacogenomics J, 10 (6), 513-23
    PubMed 20157331
  14. Fu YP, Edvardsen H, Kaushiva A, Arhancet JP, Howe TM, Kohaar I, Porter-Gill P, Shah A, Landmark-Høyvik H, Fosså SD, Ambs S, Naume B, Børresen-Dale AL, Kristensen VN, Prokunina-Olsson L (2010)
    NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
    Mol Cancer, 9, 113
    PubMed 20482849
  15. Holmøy T, Wilson JA, von der Lippe C, Andersen PM, Berg-Hansen P (2010)
    G127R: A novel SOD1 mutation associated with rapidly evolving ALS and severe pain syndrome
    Amyotroph Lateral Scler, 11 (5), 478-80
    PubMed 20192886
  16. Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J (2010)
    BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
    BMC Cancer, 10, 654
    PubMed 21118481
  17. Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
    Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
    Breast Cancer Res, 12 (4), R65
    PubMed 20799965
  18. International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J et al. (2010)
    International network of cancer genome projects
    Nature, 464 (7291), 993-8
    PubMed 20393554
  19. Jovanovic J, Rønneberg JA, Tost J, Kristensen V (2010)
    The epigenetics of breast cancer
    Mol Oncol, 4 (3), 242-54
    PubMed 20627830
  20. Kamalakaran S, Varadan V, Giercksky Russnes HE, Levy D, Kendall J, Janevski A, Riggs M, Banerjee N, Synnestvedt M, Schlichting E, Kåresen R, Shama Prasada K, Rotti H, Rao R, Rao L, Eric Tang MH, Satyamoorthy K, Lucito R, Wigler M, Dimitrova N, Naume B, Borresen-Dale AL, Hicks JB (2010)
    DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
    Mol Oncol, 5 (1), 77-92
    PubMed 21169070
  21. Kristensen V, Borresen-Dale AL (2010)
    Mutations for the people
    EMBO Mol Med, 2 (5), 143-5
    PubMed 20461736
  22. Landmark-Høyvik H, Dumeaux V, Reinertsen KV, Edvardsen H, Fosså SD, Børresen-Dale AL (2010)
    Blood gene expression profiling of breast cancer survivors experiencing fibrosis
    Int J Radiat Oncol Biol Phys, 79 (3), 875-83
    PubMed 21129856
  23. Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
    The genetics and epigenetics of fatigue
    PM R, 2 (5), 456-65
    PubMed 20656628
  24. Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Børresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS (2010)
    Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models
    BMC Cancer, 10, 433
    PubMed 20716336
  25. Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S, Amini RM, Botling J, Børresen-Dale AL, Sørlie T, Wärnberg F (2010)
    Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
    Mol Oncol, 4 (4), 357-68
    PubMed 20663721
  26. Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
    Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
    Breast Cancer Res, 12 (1), R3
    PubMed 20056007
  27. Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
    In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
    PLoS One, 5 (11), e14002
    PubMed 21124964
  28. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
    Mol. Oncol., 4 (2), 169
  29. Papp J, Kovacs ME, Solyom S, Kasler M, Børresen-Dale AL, Olah E (2010)
    High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients
    BMC Med Genet, 11, 169
    PubMed 21118512
  30. Pedersen RS, Brasch-Andersen C, Sim SC, Bergmann TK, Halling J, Petersen MS, Weihe P, Edvardsen H, Kristensen VN, Brøsen K, Ingelman-Sundberg M (2010)
    Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
    Eur J Clin Pharmacol, 66 (12), 1199-205
    PubMed 20665013
  31. Peng J, Zhu J, Bergamaschi A, Han W, Noh DY, Pollack JR, Wang P (2010)
    Regularized Multivariate Regression for Identifying Master Predictors with Application to Integrative Genomics Study of Breast Cancer
    Ann Appl Stat, 4 (1), 53-77
    PubMed 24489618
  32. Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL, FEMME Consortium (2010)
    Triple-negative breast cancer: present challenges and new perspectives
    Mol Oncol, 4 (3), 209-29
    PubMed 20537966
  33. Rantala JK, Edgren H, Lehtinen L, Wolf M, Kleivi K, Vollan HK, Aaltola AR, Laasola P, Kilpinen S, Saviranta P, Iljin K, Kallioniemi O (2010)
    Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2
    Neoplasia, 12 (11), 877-88
    PubMed 21082043
  34. Reinertsen KV, Cvancarova M, Loge JH, Edvardsen H, Wist E, Fosså SD (2010)
    Predictors and course of chronic fatigue in long-term breast cancer survivors
    J Cancer Surviv, 4 (4), 405-14
    PubMed 20862614
  35. Russnes HG, Vollan HK, Lingjaerde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL (2010)
    Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
    Sci Transl Med, 2 (38), 38ra47
    PubMed 20592421
  36. Rødningen OK, Prescott TE, Hovland R, Eiklid K, Houge G (2010)
    [Determination of chromosome aberrations with the help of DNA arrays]
    Tidsskr Nor Laegeforen, 130 (9), 944-7
    PubMed 20453958
  37. Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V (2010)
    Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
    Mol Oncol, 5 (1), 61-76
    PubMed 21212030
  38. Sørlie T, Borgan E, Myhre S, Vollan HK, Russnes H, Zhao X, Nilsen G, Lingjaerde OC, Børresen-Dale AL, Rødland E (2010)
    The importance of gene-centring microarray data
    Lancet Oncol, 11 (8), 719-20; author reply 720-1
    PubMed 20688275
  39. Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN (2010)
    Allele-specific copy number analysis of tumors
    Proc Natl Acad Sci U S A, 107 (39), 16910-5
    PubMed 20837533
  40. Aarøe J, Lindahl T, Dumeaux V, Saebø S, Tobin D, Hagen N, Skaane P, Lönneborg A, Sharma P, Børresen-Dale AL (2010)
    Gene expression profiling of peripheral blood cells for early detection of breast cancer
    Breast Cancer Res, 12 (1), R7
    PubMed 20078854

Publications 2009

  1. Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT (2009)
    Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
    Clin Cancer Res, 15 (11), 3654-62
    PubMed 19470724
  2. Andersen V, Agerstjerne L, Jensen D, Østergaard M, Saebø M, Hamfjord J, Kure E, Vogel U (2009)
    The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
    BMC Med Genet, 10, 18
    PubMed 19250544
  3. Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
    Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
    Mol Oncol, 3 (5-6), 469-82
    PubMed 19713161
  4. Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR (2009)
    Focal amplification and oncogene dependency of GAB2 in breast cancer
    Oncogene, 29 (5), 774-9
    PubMed 19881546
  5. Dossus L, Allen N, Kaaks R, Bakken K, Lund E, Tjonneland A, Olsen A, Overvad K, Clavel-Chapelon F, Fournier A, Chabbert-Buffet N, Boeing H, Schütze M, Trichopoulou A, Trichopoulos D, Lagiou P, Palli D, Krogh V, Tumino R, Vineis P, Mattiello A, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Dumeaux V et al. (2009)
    Reproductive risk factors and endometrial cancer: the European Prospective Investigation into Cancer and Nutrition
    Int J Cancer, 127 (2), 442-51
    PubMed 19924816
  6. Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S, EPIC, Haiman CA, Le Marchand L, MEC, Broeks A, Schmidt MK, ABCS, Hopper J, Southey M, ABCFS, Beckmann MW, Fasching PA, BBCC et al. (2009)
    Association of ESR1 gene tagging SNPs with breast cancer risk
    Hum Mol Genet, 18 (6), 1131-9
    PubMed 19126777
  7. Figueiredo JC, Haile RW, Bernstein L, Malone KE, Largent J, Langholz B, Lynch CF, Bertelsen L, Capanu M, Concannon P, Borg A, Børresen-Dale AL, Diep A, Teraoka S, Torngren T, Xue S, Bernstein JL (2009)
    Oral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study
    Breast Cancer Res Treat, 120 (1), 175-83
    PubMed 19597986
  8. Gaudet MM, Milne RL, Cox A, Camp NJ, Goode EL, Humphreys MK, Dunning AM, Morrison J, Giles GG, Severi G, Baglietto L, English DR, Couch FJ, Olson JE, Wang X, Chang-Claude J, Flesch-Janys D, Abbas S, Salazar R, Mannermaa A, Kataja V, Kosma VM, Lindblom A, Margolin S, Heikkinen T et al. (2009)
    Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Cancer Epidemiol Biomarkers Prev, 18 (5), 1610-6
    PubMed 19423537
  9. Geigl JB, Obenauf AC, Waldispuehl-Geigl J, Hoffmann EM, Auer M, Hörmann M, Fischer M, Trajanoski Z, Schenk MA, Baumbusch LO, Speicher MR (2009)
    Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    Nucleic Acids Res, 37 (15), e105
    PubMed 19541849
  10. Glynn SA, Boersma BJ, Howe TM, Edvardsen H, Geisler SB, Goodman JE, Ridnour LA, Lønning PE, Børresen-Dale AL, Naume B, Kristensen VN, Chanock SJ, Wink DA, Ambs S (2009)
    A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
    Clin Cancer Res, 15 (12), 4165-73
    PubMed 19509150
  11. Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB (2009)
    A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers
    Clin Proteomics, 6 (4), 129-51
    PubMed 21691416
  12. Kamalakaran S, Kendall J, Zhao X, Tang C, Khan S, Ravi K, Auletta T, Riggs M, Wang Y, Helland A, Naume B, Dimitrova N, Børresen-Dale AL, Hicks J, Lucito R (2009)
    Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
    Nucleic Acids Res, 37 (12), e89
    PubMed 19474344
  13. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
    Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
    Pharmacogenet Genomics, 19 (10), 751-9
    PubMed 19741569
  14. Landmark-Høyvik H, Reinertsen KV, Loge JH, Fosså SD, Børresen-Dale AL, Dumeaux V (2009)
    Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
    Pharmacogenomics J, 9 (5), 333-40
    PubMed 19546881
  15. Leivonen SK, Mäkelä R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, Enerly E, Aakula A, Hellström K, Sahlberg N, Kristensen VN, Børresen-Dale AL, Saviranta P, Perälä M, Kallioniemi O (2009)
    Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
    Oncogene, 28 (44), 3926-36
    PubMed 19684618
  16. Lönneborg A, Aarøe J, Dumeaux V, Børresen-Dale AL (2009)
    Found in transcription: gene expression and other novel blood biomarkers for the early detection of breast cancer
    Expert Rev Anticancer Ther, 9 (8), 1115-23
    PubMed 19671031
  17. Muggerud AA, Edgren H, Wolf M, Kleivi K, Dejeux E, Tost J, Sørlie T, Kallioniemi O (2009)
    Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
    BMC Med Genomics, 2, 26
    PubMed 19432969
  18. Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB (2009)
    Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
    PLoS One, 4 (5), e5583
    PubMed 19440550
  19. Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
    Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
    Mol Oncol, 4 (2), 98-118
    PubMed 20060370
  20. Skinningsrud B, Husebye ES, Gilfillan GD, Frengen E, Erichsen A, Gervin K, Ormerod E, Egeland T, Undlien DE (2009)
    X-linked congenital adrenal hypoplasia with hypogonadotropic hypogonadism caused by an inversion disrupting a conserved noncoding element upstream of the NR0B1 (DAX1) gene
    J Clin Endocrinol Metab, 94 (10), 4086-93
    PubMed 19773398
  21. Solvang HK, Nagahara Y, Araki S, Sawada H, Makino S (2009)
    Frequency-Domain Pearson Distribution Approach for Independent Component Analysis (FD-Pearson-ICA) in Blind Source Separation
    IEEE Trans. Audio Speech Lang. Process., 17 (4), 639-649
  22. Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE et al. (2009)
    Complex landscapes of somatic rearrangement in human breast cancer genomes
    Nature, 462 (7276), 1005-10
    PubMed 20033038
  23. Sun W, Wright FA, Tang Z, Nordgard SH, Van Loo P, Yu T, Kristensen VN, Perou CM (2009)
    Integrated study of copy number states and genotype calls using high-density SNP arrays
    Nucleic Acids Res, 37 (16), 5365-77
    PubMed 19581427
  24. Sørlie T (2009)
    Introducing molecular subtyping of breast cancer into the clinic?
    J Clin Oncol, 27 (8), 1153-4
    PubMed 19204193
  25. Vasen HF, Möslein G, Alonso A, Aretz S, Bernstein I, Bertario L, Blanco I, Bulow S, Burn J, Capella G, Colas C, Engel C, Frayling I, Rahner N, Hes FJ, Hodgson S, Mecklin JP, Møller P, Myrhøj T, Nagengast FM, Parc Y, Ponz de Leon M, Renkonen-Sinisalo L, Sampson JR, Stormorken A et al. (2009)
    Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
    Fam Cancer, 9 (2), 109-15
    PubMed 19763885
  26. Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Wärnberg F, Langerød A (2009)
    Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
    Mol Oncol, 3 (3), 214-9
    PubMed 19403344

Publications 2008

  1. Alsner J, Jensen V, Kyndi M, Offersen BV, Vu P, Børresen-Dale AL, Overgaard J (2008)
    A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
    Acta Oncol, 47 (4), 600-7
    PubMed 18465328
  2. Baumbusch LO, Aarøe J, Johansen FE, Hicks J, Sun H, Bruhn L, Gunderson K, Naume B, Kristensen VN, Liestøl K, Børresen-Dale AL, Lingjaerde OC (2008)
    Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    BMC Genomics, 9, 379
    PubMed 18691401
  3. Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR (2008)
    CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
    Mol Oncol, 2 (4), 327-39
    PubMed 19383354
  4. Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V (2008)
    p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
    Mol Syst Biol, 4, 229
    PubMed 19034270
  5. Concannon P, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Teraoka SN, Diep TA, Jansen L, Atencio DP, Langholz B, Capanu M, Liang X, Begg CB, Thomas DC, Bernstein L, Olsen JH, Malone KE, Lynch CF, Anton-Culver H, Bernstein JL, Women's Environment, Cancer, and Radiation Epidemiology Study Collaborative Group (2008)
    Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
    Cancer Res, 68 (16), 6486-91
    PubMed 18701470
  6. Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
    Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
    Breast Cancer Res, 10 (1), R13
    PubMed 18271962
  7. Dumeaux V, Lund E, Børresen-Dale AL (2008)
    Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood
    Biomark Med, 2 (1), 11-21
    PubMed 20477359
  8. Holm R, Kraus I, Skomedal H, Langerød A, Kristensen GB, Lyng H (2008)
    Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
    Open Virol J, 2, 74-81
    PubMed 19440467
  9. Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC, Kristensen VN, Børresen-Dale AL, Pollack J, van de Vijver MJ (2008)
    ESR1 gene amplification in breast cancer: a common phenomenon?
    Nat Genet, 40 (7), 807-8; author reply 810-2
    PubMed 18583965
  10. Kristensen VN, Børresen-Dale AL (2008)
    SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
    Mol Oncol, 2 (1), 12-5
    PubMed 19383324
  11. Mellemkjaer L, Dahl C, Olsen JH, Bertelsen L, Guldberg P, Christensen J, Børresen-Dale AL, Stovall M, Langholz B, Bernstein L, Lynch CF, Malone KE, Haile RW, Andersson M, Thomas DC, Concannon P, Capanu M, Boice JD, WECARE Study Collaborative Group, Bernstein JL (2008)
    Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study
    Br J Cancer, 98 (4), 728-33
    PubMed 18253122
  12. Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
    Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
    Int J Cancer, 123 (3), 577-85
    PubMed 18498133
  13. Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN (2008)
    Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
    Genes Chromosomes Cancer, 47 (8), 680-96
    PubMed 18398821
  14. Nørsett KG, Laegreid A, Kusnierczyk W, Langaas M, Ylving S, Fossmark R, Myhre S, Falkmer S, Waldum HL, Sandvik AK (2008)
    Changes in gene expression of gastric mucosa during therapeutic acid inhibition
    Eur J Gastroenterol Hepatol, 20 (7), 613-23
    PubMed 18679062
  15. Olivier M, Petitjean A, Teague J, Forbes S, Dunnick JK, den Dunnen JT, Langerød A, Wilkinson JM, Vihinen M, Cotton RG, Hainaut P, IARC, EC FP6 (2008)
    Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration
    Hum Mutat, 30 (3), 275-82
    PubMed 19006239
  16. Pietersen AM, Horlings HM, Hauptmann M, Langerød A, Ajouaou A, Cornelissen-Steijger P, Wessels LF, Jonkers J, van de Vijver MJ, van Lohuizen M (2008)
    EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
    Breast Cancer Res, 10 (6), R109
    PubMed 19099573
  17. Prescott TE, Rødningen OK, Bjørnstad A, Stray-Pedersen A (2008)
    Two brothers with a microduplication including the MECP2 gene: rapid head growth in infancy and resolution of susceptibility to infection
    Clin Dysmorphol, 18 (2), 78-82
    PubMed 19057379
  18. Rønneberg JA, Tost J, Solvang HK, Alnaes GI, Johansen FE, Brendeford EM, Yakhini Z, Gut IG, Lønning PE, Børresen-Dale AL, Gabrielsen OS, Kristensen VN (2008)
    GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
    Cancer Res, 68 (14), 5562-71
    PubMed 18632608
  19. Saebo S, Almoy T, Aaroe J, Aastveit AH (2008)
    ST-PLS: a multi-directional nearest shrunken centroid type classi er via PLS
    J. Chemometr., 22 (1-2), 54-62
  20. Saebø M, Skjelbred CF, Brekke Li K, Bowitz Lothe IM, Hagen PC, Johnsen E, Tveit KM, Kure EH (2008)
    CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas
    Anticancer Res, 28 (4C), 2289-95
    PubMed 18751408
  21. Solvang HK, Ishizuka K, Fujimoto M (2008)
    Voice activity detection based on adjustable linear prediction and GARCH models
    Speech Commun., 50 (6), 476-486
  22. Suspitsin EN, Due EU, Vu P, Hirvonen A, Børresen-Dale AL, Imyanitov EN (2008)
    TP53 mutations in synchronous and metachronous bilateral breast carcinomas
    Cancer Genet Cytogenet, 184 (2), 119-21
    PubMed 18617062
  23. Tongbai R, Idelman G, Nordgard SH, Cui W, Jacobs JL, Haggerty CM, Chanock SJ, Børresen-Dale AL, Livingston G, Shaunessy P, Chiang CH, Kristensen VN, Bilke S, Gardner K (2008)
    Transcriptional networks inferred from molecular signatures of breast cancer
    Am J Pathol, 172 (2), 495-509
    PubMed 18187569
  24. Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P (2008)
    Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients
    Pharmacogenet Genomics, 18 (3), 263-73
    PubMed 18300948
  25. Waaseth M, Bakken K, Dumeaux V, Olsen KS, Rylander C, Figenschau Y, Lund E (2008)
    Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer postgenome cohort - a cross-sectional analysis
    BMC Womens Health, 8, 1
    PubMed 18194511

Publications 2007

  1. Alsner J, Rødningen OK, Overgaard J (2007)
    Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis
    Radiother Oncol, 83 (3), 261-6
    PubMed 17512072
  2. Ben-Dor A, Lipson D, Tsalenko A, Reimers M, Baumbusch LO, Barrett MT, Weinstein JN, Borresen-Dale AL, Yakhini Z (2007)
    Framework for identifying common aberrations in DNA copy number data
    LECT NOTES COMPUT SC, 4453, 122-136
  3. Bergamaschi A, Tagliabue E, Sørlie T, Naume B, Triulzi T, Orlandi R, Russnes HG, Nesland JM, Tammi R, Auvinen P, Kosma VM, Ménard S, Børresen-Dale AL (2007)
    Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
    J Pathol, 214 (3), 357-67
    PubMed 18044827
  4. Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
    Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
    BMC Cancer, 7, 197
    PubMed 17956601
  5. Casalini P, Iorio MV, Berno V, Bergamaschi A, Børresen Dale AL, Gasparini P, Orlandi R, Casati B, Tagliabue E, Ménard S (2007)
    Relationship between p53 and p27 expression following HER2 signaling
    Breast, 16 (6), 597-605
    PubMed 17604627
  6. Chanock SJ, Burdett L, Yeager M, Llaca V, Langerød A, Presswalla S, Kaaresen R, Strausberg RL, Gerhard DS, Kristensen V, Perou CM, Børresen-Dale AL (2007)
    Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
    Breast Cancer Res, 9 (1), R5
    PubMed 17224074
  7. Davidson B, Skrede M, Silins I, Shih IeM, Trope CG, Flørenes VA (2007)
    Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma
    Cancer, 110 (6), 1264-71
    PubMed 17647260
  8. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
    Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
    Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
    PubMed 17336217
  9. Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL (2007)
    Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
    Radiat Oncol, 2, 25
    PubMed 17623063
  10. Garcia-Closas M, Kristensen V, Langerød A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Børresen-Dale AL, Chanock S (2007)
    Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
    Int J Cancer, 121 (11), 2532-8
    PubMed 17683073
  11. Garcia-Closas M, Troester MA, Qi Y, Langerød A, Yeager M, Lissowska J, Brinton L, Welch R, Peplonska B, Gerhard DS, Gram IT, Kristensen V, Børresen-Dale AL, Chanock S, Perou CM (2007)
    Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
    Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
    PubMed 18006915
  12. Kapp AV, Jeffrey SS, Langerod A, Borresen-Dale AL, Han W, Noh DY, Bukholm IRK, Nicolau M, Brown PO, Tibshirani R (2007)
    Discovery and validation of breast cancer subtypes (vol 8, pg 101, 2007)
    BMC Genomics, 8, 101
  13. Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E (2007)
    Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (11), 1221-30
    PubMed 17404387
  14. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
    Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
    Mol Cancer, 6, 2
    PubMed 17201907
  15. Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE (2007)
    Mutations and polymorphisms of the p21B transcript in breast cancer
    Int J Cancer, 121 (4), 908-10
    PubMed 17443496
  16. Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2007)
    Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
    Genet Epidemiol, 32 (2), 168-78
    PubMed 17968987
  17. Landmark H, Nahas SA, Aarøe J, Gatti R, Børresen-Dale AL, Rødningen OK (2007)
    Transcriptional response to ionizing radiation in human radiation sensitive cell lines
    Radiother Oncol, 83 (3), 256-60
    PubMed 17512073
  18. Langerød A, Zhao H, Borgan Ø, Nesland JM, Bukholm IR, Ikdahl T, Kåresen R, Børresen-Dale AL, Jeffrey SS (2007)
    TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    Breast Cancer Res, 9 (3), R30
    PubMed 17504517
  19. Lorentzen A, Vogel LK, Lewinsky RH, Saebø M, Skjelbred CF, Godiksen S, Hoff G, Tveit KM, Lothe IM, Ikdahl T, Kure EH, Mitchelmore C (2007)
    Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
    BMC Cancer, 7, 192
    PubMed 17935612
  20. Lund E, Bakken K, Dumeaux V, Andersen V, Kumle M (2007)
    Hormone replacement therapy and breast cancer in former users of oral contraceptives--The Norwegian Women and Cancer study
    Int J Cancer, 121 (3), 645-8
    PubMed 17372914
  21. Lund E, Dumeaux V, Braaten T, Hjartåker A, Engeset D, Skeie G, Kumle M (2007)
    Cohort profile: The Norwegian Women and Cancer Study--NOWAC--Kvinner og kreft
    Int J Epidemiol, 37 (1), 36-41
    PubMed 17644530
  22. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    Mol Oncol, 1 (2), 160-71
    PubMed 19383292
  23. Nicolau M, Tibshirani R, Børresen-Dale AL, Jeffrey SS (2007)
    Disease-specific genomic analysis: identifying the signature of pathologic biology
    Bioinformatics, 23 (8), 957-65
    PubMed 17277331
  24. Nordgard SH, Johansen FE, Alnaes GI, Naume B, Børresen-Dale AL, Kristensen VN (2007)
    Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
    Breast Cancer Res, 9 (6), 113
    PubMed 18036273
  25. Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN (2007)
    ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
    Pharmacogenet Genomics, 17 (2), 127-36
    PubMed 17301692
  26. Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2007)
    TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
    Oncogene, 26 (15), 2157-65
    PubMed 17401424
  27. Riise R, Ygge J, Lindman C, Stray-Pedersen A, Bek T, Rødningen OK, Heiberg A (2007)
    Ocular findings in Norwegian patients with ataxia-telangiectasia: a 5 year prospective cohort study
    Acta Ophthalmol Scand, 85 (5), 557-62
    PubMed 17376192
  28. Roca X, Olson AJ, Rao AR, Enerly E, Kristensen VN, Børresen-Dale AL, Andresen BS, Krainer AR, Sachidanandam R (2007)
    Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
    Genome Res, 18 (1), 77-87
    PubMed 18032726
  29. Rødningen OK, Børresen-Dale AL, Alsner J, Hastie T, Overgaard J (2007)
    Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis
    Radiother Oncol, 86 (3), 314-20
    PubMed 17963910
  30. Sikkeland LI, Haug T, Stangeland AM, Flatberg G, Søstrand P, Halvorsen B, Kongerud J (2007)
    Airway inflammation in paper mill workers
    J Occup Environ Med, 49 (10), 1135-42
    PubMed 18000418
  31. Sikkeland LI, Kongerud J, Stangeland AM, Haug T, Alexis NE (2007)
    Macrophage enrichment from induced sputum
    Thorax, 62 (6), 558-9
    PubMed 17536036
  32. Stray-Pedersen A, Borresen-Dale AL, Paus E, Lindman CR, Burgers T, Abrahamsen TG (2007)
    Alpha fetoprotein is increasing with age in ataxia-telangiectasia
    Eur J Paediatr Neurol, 11 (6), 375-80
    PubMed 17540590
  33. Størvold GL, Gjernes E, Askautrud HA, Børresen-Dale AL, Perou CM, Frengen E (2007)
    A retroviral vector for siRNA expression in mammalian cells
    Mol Biotechnol, 35 (3), 275-82
    PubMed 17652791
  34. Vasen HF, Möslein G, Alonso A, Bernstein I, Bertario L, Blanco I, Burn J, Capella G, Engel C, Frayling I, Friedl W, Hes FJ, Hodgson S, Mecklin JP, Møller P, Nagengast F, Parc Y, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Wijnen J (2007)
    Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
    J Med Genet, 44 (6), 353-62
    PubMed 17327285
  35. Wang Y, Kristensen GB, Børresen-Dale AL, Helland A (2007)
    TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients
    Ann Oncol, 18 (5), 964-6
    PubMed 17488735
  36. Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R (2007)
    A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
    Bioinformatics, 23 (2), e91-8
    PubMed 17237111

Publications 2006

  1. Anensen N, Skavland J, Stapnes C, Ryningen A, Børresen-Dale AL, Gjertsen BT, Bruserud Ø (2006)
    Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report
    Leukemia, 20 (4), 734-6
    PubMed 16437140
  2. Baumbusch LO, Myhre S, Langerød A, Bergamaschi A, Geisler SB, Lønning PE, Deppert W, Dornreiter I, Børresen-Dale AL (2006)
    Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters
    Mol Cancer, 5, 47
    PubMed 17054774
  3. Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR (2006)
    Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
    Genes Chromosomes Cancer, 45 (11), 1033-40
    PubMed 16897746
  4. Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO (2006)
    Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    PLoS Med, 3 (3), e47
    PubMed 16417408
  5. Crockford GP, Linger R, Hockley S, Dudakia D, Johnson L, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Bonaïti-Pellié C, Heidenreich A, Albers P, Olah E, Geczi L, Bodrogi I, Ormiston WJ, Daly PA, Guilford P, Fosså SD et al. (2006)
    Genome-wide linkage screen for testicular germ cell tumour susceptibility loci
    Hum Mol Genet, 15 (3), 443-51
    PubMed 16407372
  6. Dumeaux V, Johansen J, Børresen-Dale AL, Lund E (2006)
    Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy
    Mol Cancer Ther, 5 (4), 868-76
    PubMed 16648556
  7. Edvardsen H, Irene Grenaker Alnaes G, Tsalenko A, Mulcahy T, Yuryev A, Lindersson M, Lien S, Omholt S, Syvänen AC, Børresen-Dale AL, Kristensen VN (2006)
    Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
    Pharmacogenet Genomics, 16 (3), 207-17
    PubMed 16495780
  8. Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R (2006)
    RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
    Carcinogenesis, 27 (8), 1593-9
    PubMed 16474176
  9. Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL (2006)
    Radiation-induced effects on gene expression: an in vivo study on breast cancer
    Radiother Oncol, 80 (2), 230-5
    PubMed 16890317
  10. Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, Schlicting E, Norton L, Hägerström T, Skoog L, Auer G, Månér S, Lundin P, Zetterberg A (2006)
    Novel patterns of genome rearrangement and their association with survival in breast cancer
    Genome Res, 16 (12), 1465-79
    PubMed 17142309
  11. Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT (2006)
    Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53
    Blood, 109 (6), 2589-96
    PubMed 17105820
  12. Jensen T, Retterstøl LJ, Sandset PM, Godal HC, Skjønsberg OH (2006)
    A daily glass of red wine induces a prolonged reduction in plasma viscosity: a randomized controlled trial
    Blood Coagul Fibrinolysis, 17 (6), 471-6
    PubMed 16905951
  13. Kapp AV, Jeffrey SS, Langerød A, Børresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R (2006)
    Discovery and validation of breast cancer subtypes
    BMC Genomics, 7, 231
    PubMed 16965636
  14. Kleivi K (2006)
    Advances in the genetics and epigenetics of gene regulation and human disease
    Genome Biol, 7 (8), 325
    PubMed 16934107
  15. Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
    Genetic variation in putative regulatory loci controlling gene expression in breast cancer
    Proc Natl Acad Sci U S A, 103 (20), 7735-40
    PubMed 16684880
  16. Kristensen VN, Tsalenko A, Geisler J, Faldaas A, Grenaker GI, Lingjaerde OC, Fjeldstad S, Yakhini Z, Lønning PE, Børresen-Dale AL (2006)
    Multilocus analysis of SNP and metabolic data within a given pathway
    BMC Genomics, 7, 5
    PubMed 16412218
  17. Lahermo P, Liljedahl U, Alnaes G, Axelsson T, Brookes AJ, Ellonen P, Groop PH, Halldén C, Holmberg D, Holmberg K, Keinänen M, Kepp K, Kere J, Kiviluoma P, Kristensen V, Lindgren C, Odeberg J, Osterman P, Parkkonen M, Saarela J, Sterner M, Strömqvist L, Talas U, Wessman M, Palotie A et al. (2006)
    A quality assessment survey of SNP genotyping laboratories
    Hum Mutat, 27 (7), 711-4
    PubMed 16786507
  18. Langholz B, Bernstein JL, Bernstein L, Olsen JH, Børresen-Dale AL, Rosenstein BS, Gatti RA, WECARE Study Collaborative Group, Concannon P (2006)
    On the proposed association of the ATM variants 5557G>A and IVS38-8T>C and bilateral breast cancer
    Int J Cancer, 119 (3), 724-5
    PubMed 16496408
  19. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
    ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
    Cell Oncol, 28 (5-6), 259-72
    PubMed 17167179
  20. Lønning PE, Børresen-Dale AL (2006)
    Interaction between p53 staining and high-dose chemotherapy in breast cancer
    Clin Cancer Res, 12 (7 Pt 1), 2289
    PubMed 16609046
  21. Muggerud AA, Johnsen H, Barnes DA, Steel A, Lønning PE, Naume B, Sørlie T, Børresen-Dale AL (2006)
    Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
    BMC Cancer, 6, 59
    PubMed 16536878
  22. Myhre S, Tveit H, Mollestad T, Laegreid A (2006)
    Additional gene ontology structure for improved biological reasoning
    Bioinformatics, 22 (16), 2020-7
    PubMed 16787968
  23. Olivier M, Langerød A, Carrieri P, Bergh J, Klaar S, Eyfjord J, Theillet C, Rodriguez C, Lidereau R, Bièche I, Varley J, Bignon Y, Uhrhammer N, Winqvist R, Jukkola-Vuorinen A, Niederacher D, Kato S, Ishioka C, Hainaut P, Børresen-Dale AL (2006)
    The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
    Clin Cancer Res, 12 (4), 1157-67
    PubMed 16489069
  24. Paracchini V, Raimondi S, Gram IT, Kang D, Kocabas NA, Kristensen VN, Li D, Parl FF, Rylander-Rudqvist T, Soucek P, Zheng W, Wedren S, Taioli E (2006)
    Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (2), 115-25
    PubMed 17053044
  25. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
    Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
    Mol Cancer, 5, 33
    PubMed 16952311
  26. Shaposhnikov SA, Akopov SB, Chernov IP, Thomsen PD, Joergensen C, Collins AR, Frengen E, Nikolaev LG (2006)
    A map of nuclear matrix attachment regions within the breast cancer loss-of-heterozygosity region on human chromosome 16q22.1
    Genomics, 89 (3), 354-61
    PubMed 17188460
  27. Storlazzi CT, Brekke HR, Mandahl N, Brosjö O, Smeland S, Lothe RA, Mertens F (2006)
    Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    J Pathol, 209 (4), 492-500
    PubMed 16721726
  28. Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE (2006)
    The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
    Clin Cancer Res, 12 (20 Pt 1), 6000-4
    PubMed 17062672
  29. Suspitsin EN, Sokolenko AP, Togo AV, Lazareva YR, Turkevich EA, Matsko DE, Henrich KO, Borresen-Dale AL, Schwab M, Cornelisse CJ, Imyanitov EN (2006)
    Nonrandom distribution of oncogene amplifications in bilateral breast carcinomas: Possible role of host factors and survival bias
    Int J Cancer, 120 (2), 297-302
    PubMed 17066426
  30. Sørlie T (2006)
    Molecular classification of breast tumors: toward improved diagnostics and treatments
    Methods Mol Biol, 360, 91-114
    PubMed 17172726
  31. Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE (2006)
    Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
    Mol Cancer Ther, 5 (11), 2914-8
    PubMed 17121939
  32. Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL (2006)
    Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
    BMC Genomics, 7, 127
    PubMed 16729877
  33. Tavtigian SV, Pierotti MA, Børresen-Dale AL (2006)
    International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'
    Breast Cancer Res, 8 (6), 303
    PubMed 17096863
  34. Tommiska J, Jansen L, Kilpivaara O, Edvardsen H, Kristensen V, Tamminen A, Aittomäki K, Blomqvist C, Børresen-Dale AL, Nevanlinna H (2006)
    ATM variants and cancer risk in breast cancer patients from Southern Finland
    BMC Cancer, 6, 209
    PubMed 16914028
  35. Tsalenko A, Sharan R, Kristensen V, Edvardsen H, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2006)
    Analysis of SNP-expression association matrices
    J Bioinform Comput Biol, 4 (2), 259-74
    PubMed 16819783
  36. von Eyben FE, Jacobsen GK, Skotheim RI, von der Maase H, Rorth M (2006)
    Precursor lesions in testis and dysgenetic gonads
    Hum Pathol, 37 (6), 773; author reply 774
    PubMed 16733221
  37. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MMO, Olivier M, Skomedal H, Hainaut P, Trope CG, Abeler VM, Nesland JM, Borresen-Dale AL, Helland A (2006)
    Effect of the codon 72 polymorphism (c.215G > C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma (vol 24, pg 21, 2004)
    Hum. Mutat., 27 (2), 209-210

Publications 2005

  1. Agesen TH, Flørenes VA, Molenaar WM, Lind GE, Berner JM, Plaat BE, Komdeur R, Myklebost O, van den Berg E, Lothe RA (2005)
    Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors
    J Neuropathol Exp Neurol, 64 (1), 74-81
    PubMed 15715087
  2. Castro P, Eknaes M, Teixeira MR, Danielsen HE, Soares P, Lothe RA, Sobrinho-Simões M (2005)
    Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
    J Pathol, 206 (3), 305-11
    PubMed 15852498
  3. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ (2005)
    Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    Proc Natl Acad Sci U S A, 102 (10), 3738-43
    PubMed 15701700
  4. Come SE, Buzdar AU, Ingle JN, Arteaga CL, Brodie AM, Colditz GA, Johnston SR, Kristensen VN, Lønning PE, McDonnell DP, Osborne CK, Russo J, Santen RJ, Yee D, Hart CS (2005)
    Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
    Clin Cancer Res, 11 (2 Pt 2), 861s-4s
    PubMed 15701878
  5. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2005)
    The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
    Genes Chromosomes Cancer, 45 (1), 31-41
    PubMed 16145679
  6. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2005)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    PubMed 16381016
  7. Dumeaux V, Fournier A, Lund E, Clavel-Chapelon F (2005)
    Previous oral contraceptive use and breast cancer risk according to hormone replacement therapy use among postmenopausal women
    Cancer Causes Control, 16 (5), 537-44
    PubMed 15986108
  8. Hofer MD, Browne TJ, He L, Skotheim RI, Lothe RA, Rubin MA (2005)
    Identification of two molecular groups of seminomas by using expression and tissue microarrays
    Clin Cancer Res, 11 (16), 5722-9
    PubMed 16115909
  9. Kringen P, Bergamaschi A, Due EU, Wang Y, Tagliabue E, Nesland JM, Nehman A, Tönisson N, Børresen-Dale AL (2005)
    Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas
    Biotechniques, 39 (5), 755-61
    PubMed 16312222
  10. Kringen P, Wang Y, Dumeaux V, Nesland JM, Kristensen G, Borresen-Dale AL, Dorum A (2005)
    TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
    BMC Cancer, 5, 134
    PubMed 16229746
  11. Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
    Clin Cancer Res, 11 (2 Pt 2), 878s-83s
    PubMed 15701881
  12. Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
    J Steroid Biochem Mol Biol, 95 (1-5), 105-11
    PubMed 16023338
  13. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Henrique R, Saatcioglu F, Esteller M, Teixeira MR, Lothe RA (2005)
    The loss of NKX3.1 expression in testicular--and prostate--cancers is not caused by promoter hypermethylation
    Mol Cancer, 4 (1), 8
    PubMed 15691383
  14. Lønning PE, Sørlie T, Børresen-Dale AL (2005)
    Genomics in breast cancer-therapeutic implications
    Nat Clin Pract Oncol, 2 (1), 26-33
    PubMed 16264853
  15. Maguire P, Margolin S, Skoglund J, Sun XF, Gustafsson JA, Børresen-Dale AL, Lindblom A (2005)
    Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer
    Breast Cancer Res Treat, 94 (2), 145-52
    PubMed 16261413
  16. Olsen JH, Hahnemann JM, Børresen-Dale AL, Tretli S, Kleinerman R, Sankila R, Hammarström L, Robsahm TE, Kääriäinen H, Bregård A, Brøndum-Nielsen K, Yuen J, Tucker M (2005)
    Breast and other cancers in 1445 blood relatives of 75 Nordic patients with ataxia telangiectasia
    Br J Cancer, 93 (2), 260-5
    PubMed 15942625
  17. Ribeiro FR, Diep CB, Jerónimo C, Henrique R, Lopes C, Eknaes M, Lingjaerde OC, Lothe RA, Teixeira MR (2005)
    Statistical dissection of genetic pathways involved in prostate carcinogenesis
    Genes Chromosomes Cancer, 45 (2), 154-63
    PubMed 16235241
  18. Rødningen OK, Overgaard J, Alsner J, Hastie T, Børresen-Dale AL (2005)
    Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
    Radiother Oncol, 77 (3), 231-40
    PubMed 16297999
  19. Schaner ME, Davidson B, Skrede M, Reich R, Flørenes VA, Risberg B, Berner A, Goldberg I, Givant-Horwitz V, Tropè CG, Kristensen GB, Nesland JM, Børresen-Dale AL (2005)
    Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients
    Mol Cancer, 4, 26
    PubMed 16042759
  20. Sharma P, Sahni NS, Tibshirani R, Skaane P, Urdal P, Berghagen H, Jensen M, Kristiansen L, Moen C, Sharma P, Zaka A, Arnes J, Sauer T, Akslen LA, Schlichting E, Børresen-Dale AL, Lönneborg A (2005)
    Early detection of breast cancer based on gene-expression patterns in peripheral blood cells
    Breast Cancer Res, 7 (5), R634-44
    PubMed 16168108
  21. Skotheim RI, Lind GE, Monni O, Nesland JM, Abeler VM, Fosså SD, Duale N, Brunborg G, Kallioniemi O, Andrews PW, Lothe RA (2005)
    Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development
    Cancer Res, 65 (13), 5588-98
    PubMed 15994931
  22. Thorstensen L, Lind GE, Løvig T, Diep CB, Meling GI, Rognum TO, Lothe RA (2005)
    Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
    Neoplasia, 7 (2), 99-108
    PubMed 15802015
  23. Tsalenko A, Sharan R, Edvardsen H, Kristensen V, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2005)
    Analysis of SNP-expression association matrices
    Proc IEEE Comput Syst Bioinform Conf, 135-43
    PubMed 16447971
  24. von Eyben FE, Jacobsen GK, Skotheim RI (2005)
    Microinvasive germ cell tumor of the testis
    Virchows Arch, 447 (3), 610-25
    PubMed 15968545
  25. Wang Y, Helland A, Holm R, Kristensen GB, Børresen-Dale AL (2005)
    PIK3CA mutations in advanced ovarian carcinomas
    Hum Mutat, 25 (3), 322
    PubMed 15712344
  26. Wang Y, Kristensen GB, Helland A, Nesland JM, Børresen-Dale AL, Holm R (2005)
    Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
    Am J Clin Pathol, 124 (3), 392-401
    PubMed 16191507
  27. Wolf M, Edgren H, Muggerud A, Kilpinen S, Huusko P, Sørlie T, Mousses S, Kallioniemi O (2005)
    NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
    Cell Oncol, 27 (3), 169-73
    PubMed 16037637
  28. Aas T, Geisler S, Helle H, Børresen-Dale AL, Lønning PE, Akslen LA (2005)
    Prognostic and predictive value of changes in tumour cell proliferation in locally advanced breast cancer primarily treated with doxorubicin
    Oncol Rep, 13 (3), 525-30
    PubMed 15706428

Publications 2004

  1. Benetkiewicz M, Wang Y, Schaner M, Wang P, Mantripragada KK, Buckley PG, Kristensen G, Børresen-Dale AL, Dumanski JP (2004)
    High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas
    Genes Chromosomes Cancer, 42 (3), 228-37
    PubMed 15578687
  2. Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Børresen-Dale AL, Concannon P, Thompson WD, WECARE study (2004)
    Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study
    Breast Cancer Res, 6 (3), R199-214
    PubMed 15084244
  3. Diep CB, Teixeira MR, Thorstensen L, Wiig JN, Eknaes M, Nesland JM, Giercksky KE, Johansson B, Lothe RA (2004)
    Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patients
    Mol Cancer, 3, 6
    PubMed 14977426
  4. Dumeaux V, Lund E, Hjartåker A (2004)
    Use of oral contraceptives, alcohol, and risk for invasive breast cancer
    Cancer Epidemiol Biomarkers Prev, 13 (8), 1302-7
    PubMed 15298950
  5. Kildal W, Kaern J, Kraggerud SM, Abeler VM, Sudbø J, Tropè CG, Lothe RA, Danielsen HE (2004)
    Evaluation of genomic changes in a large series of malignant ovarian germ cell tumors--relation to clinicopathologic variables
    Cancer Genet Cytogenet, 155 (1), 25-32
    PubMed 15527899
  6. Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2004)
    TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
    J Pathol, 207 (1), 14-9
    PubMed 16007576
  7. Kleivi K, Teixeira MR, Eknaes M, Diep CB, Jakobsen KS, Hamelin R, Lothe RA (2004)
    Genome signatures of colon carcinoma cell lines
    Cancer Genet Cytogenet, 155 (2), 119-31
    PubMed 15571797
  8. Lind GE, Thorstensen L, Løvig T, Meling GI, Hamelin R, Rognum TO, Esteller M, Lothe RA (2004)
    A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
    Mol Cancer, 3, 28
    PubMed 15476557
  9. Lingjaerde OC, Baumbusch LO, Liestøl K, Glad IK, Børresen-Dale AL (2004)
    CGH-Explorer: a program for analysis of array-CGH data
    Bioinformatics, 21 (6), 821-2
    PubMed 15531610
  10. Moger TA, Aalen OO, Heimdal K, Gjessing HK (2004)
    Analysis of testicular cancer data using a frailty model with familial dependence
    Stat Med, 23 (4), 617-32
    PubMed 14755393
  11. Richard SM, Bianchi NO, Bianchi MS, Peltomäki P, Lothe RA, Pavicic W (2004)
    Ethnic variation in the prevalence of AZF deletions in testicular cancer
    Mutat Res, 554 (1-2), 45-51
    PubMed 15450403
  12. Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW et al. (2004)
    Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
    Int J Cancer, 110 (2), 266-70
    PubMed 15069692
  13. Soucek P, Skjelbred CF, Svendsen M, Kristensen T, Kure EH, Kristensen VN (2004)
    Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
    BMC Biotechnol, 4, 28
    PubMed 15563733
  14. Stray-Pedersen A, Jónsson T, Heiberg A, Lindman CR, Widing E, Aaberge IS, Borresen-Dale AL, Abrahamsen TG (2004)
    The impact of an early truncating founder ATM mutation on immunoglobulins, specific antibodies and lymphocyte populations in ataxia-telangiectasia patients and their parents
    Clin Exp Immunol, 137 (1), 179-86
    PubMed 15196260
  15. Staalesen V, Falck J, Geisler S, Bartkova J, Børresen-Dale AL, Lukas J, Lillehaug JR, Bartek J, Lønning PE (2004)
    Alternative splicing and mutation status of CHEK2 in stage III breast cancer
    Oncogene, 23 (52), 8535-44
    PubMed 15361853
  16. Sørlie T (2004)
    Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
    Eur J Cancer, 40 (18), 2667-75
    PubMed 15571950
  17. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2004)
    Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
    Methods Mol Biol, 291, 207-16
    PubMed 15502225
  18. Teixeira MR, Ribeiro FR, Eknaes M, Waehre H, Stenwig AE, Giercksky KE, Heim S, Lothe RA (2004)
    Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making
    Cancer, 101 (8), 1786-93
    PubMed 15386312
  19. Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM (2004)
    Cell-type-specific responses to chemotherapeutics in breast cancer
    Cancer Res, 64 (12), 4218-26
    PubMed 15205334
  20. Usary J, Llaca V, Karaca G, Presswala S, Karaca M, He X, Langerød A, Kåresen R, Oh DS, Dressler LG, Lønning PE, Strausberg RL, Chanock S, Børresen-Dale AL, Perou CM (2004)
    Mutation of GATA3 in human breast tumors
    Oncogene, 23 (46), 7669-78
    PubMed 15361840
  21. Wang Y, Helland A, Holm R, Skomedal H, Abeler VM, Danielsen HE, Tropé CG, Børresen-Dale AL, Kristensen GB (2004)
    TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
    Br J Cancer, 90 (3), 678-85
    PubMed 14760384
  22. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MM, Olivier M, Skomedal H, Hainaut P, Tropé CG, Abeler VM, Nesland JM, Børresen-Dale AL, Helland A (2004)
    Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
    Hum Mutat, 24 (1), 21-34
    PubMed 15221786
  23. Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS (2004)
    Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
    Mol Biol Cell, 15 (6), 2523-36
    PubMed 15034139
  24. Zimarina TC, Kristensen VN, Imianitov EN, Bershte?n LM (2004)
    [Polymorphisms of CYP1B1 and COMT in breast and endometrial cancer]
    Mol Biol (Mosk), 38 (3), 386-93
    PubMed 15285606

Publications 2003

  1. Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Børresen-Dale AL, Gatti RA, Concannon P, Haile RW, WECARE Study Collaborative Group (2003)
    ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer
    Br J Cancer, 89 (8), 1513-6
    PubMed 14562025
  2. Bernstein JL, Teraoka S, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P, WECARE Study Collaborative Group (2003)
    Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer
    Hum Mutat, 21 (5), 542-50
    PubMed 12673797
  3. Brandal P, Micci F, Bjerkehagen B, Eknaes M, Larramendy M, Lothe RA, Knuutila S, Heim S (2003)
    Molecular cytogenetic characterization of desmoid tumors
    Cancer Genet Cytogenet, 146 (1), 1-7
    PubMed 14499689
  4. Bukholm IR, Husdal A, Nesland JM, Langerød A, Bukholm G (2003)
    Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time
    Breast Cancer Res Treat, 80 (2), 199-206
    PubMed 12908823
  5. Børresen-Dale AL (2003)
    TP53 and breast cancer
    Hum Mutat, 21 (3), 292-300
    PubMed 12619115
  6. Børresen-Dale AL (2003)
    Genetic profiling of breast cancer: from molecular portraits to clinical utility
    Int J Biol Markers, 18 (1), 54-6
    PubMed 12699064
  7. Diep CB, Thorstensen L, Meling GI, Skovlund E, Rognum TO, Lothe RA (2003)
    Genetic tumor markers with prognostic impact in Dukes' stages B and C colorectal cancer patients
    J Clin Oncol, 21 (5), 820-9
    PubMed 12610180
  8. Dumeaux V, Alsaker E, Lund E (2003)
    Breast cancer and specific types of oral contraceptives: a large Norwegian cohort study
    Int J Cancer, 105 (6), 844-50
    PubMed 12767072
  9. Geisler S, Børresen-Dale AL, Johnsen H, Aas T, Geisler J, Akslen LA, Anker G, Lønning PE (2003)
    TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer
    Clin Cancer Res, 9 (15), 5582-8
    PubMed 14654539
  10. Haslekås C, Grini PE, Nordgard SH, Thorstensen T, Viken MK, Nygaard V, Aalen RB (2003)
    ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress
    Plant Mol Biol, 53 (3), 313-26
    PubMed 14750521
  11. Haslekås C, Viken MK, Grini PE, Nygaard V, Nordgard SH, Meza TJ, Aalen RB (2003)
    Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress
    Plant Physiol, 133 (3), 1148-57
    PubMed 14526116
  12. Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A (2003)
    Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
    Oncogene, 22 (34), 5358-61
    PubMed 12917637
  13. Kildal W, Kraggerud SM, Abeler VM, Heim S, Tropé CG, Kristensen GB, Risberg B, Lothe RA, Danielsen HE (2003)
    Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
    Hum Pathol, 34 (9), 946-9
    PubMed 14562293
  14. Kraggerud SM, Lee MP, Skotheim RI, Stenwig AE, Fosså SD, Feinberg AP, Lothe RA (2003)
    Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors
    Cancer Genet Cytogenet, 147 (1), 1-8
    PubMed 14580764
  15. Kristiansen M, Helland A, Kristensen GB, Olsen AO, Lønning PE, Børresen-Dale AL, Ørstavik KH (2003)
    X chromosome inactivation in cervical cancer patients
    Cancer Genet Cytogenet, 146 (1), 73-6
    PubMed 14499700
  16. Langerød A, Strømberg M, Chin K, Kristensen VN, Børresen-Dale AL (2003)
    BUB1 infrequently mutated in human breast carcinomas
    Hum Mutat, 22 (5), 420
    PubMed 14517964
  17. Løvig T, Thorstensen L, Hofstad B, Andersen SN, Clausen OP, Vatn M, Lothe RA, Rognum TO (2003)
    Genetic and protein markers related to in situ growth and multiplicity in small sporadic colorectal adenomas
    Scand J Gastroenterol, 38 (3), 298-306
    PubMed 12737446
  18. Pan-Hammarström Q, Dai S, Zhao Y, van Dijk-Härd IF, Gatti RA, Børresen-Dale AL, Hammarström L (2003)
    ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region
    J Immunol, 170 (7), 3707-16
    PubMed 12646636
  19. Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO et al. (2003)
    Gene expression patterns in ovarian carcinomas
    Mol Biol Cell, 14 (11), 4376-86
    PubMed 12960427
  20. Skotheim RI, Abeler VM, Nesland JM, Fosså SD, Holm R, Wagner U, Flørenes VA, Aass N, Kallioniemi OP, Lothe RA (2003)
    Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays
    Neoplasia, 5 (5), 397-404
    PubMed 14670177
  21. Skotheim RI, Kallioniemi A, Bjerkhagen B, Mertens F, Brekke HR, Monni O, Mousses S, Mandahl N, Soeter G, Nesland JM, Smeland S, Kallioniemi OP, Lothe RA (2003)
    Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome
    J Clin Oncol, 21 (24), 4586-91
    PubMed 14673046
  22. Skotheim RI, Korkmaz KS, Klokk TI, Abeler VM, Korkmaz CG, Nesland JM, Fosså SD, Lothe RA, Saatcioglu F (2003)
    NKX3.1 expression is lost in testicular germ cell tumors
    Am J Pathol, 163 (6), 2149-54
    PubMed 14633588
  23. Skotheim RI, Lothe RA (2003)
    The testicular germ cell tumour genome
    APMIS, 111 (1), 136-50; discussion 50-1
    PubMed 12752254
  24. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003)
    Repeated observation of breast tumor subtypes in independent gene expression data sets
    Proc Natl Acad Sci U S A, 100 (14), 8418-23
    PubMed 12829800
  25. Soucek P, Gut I, Trneny M, Skovlund E, Grenaker Alnaes G, Kristensen T, Børresen-Dale AL, Kristensen VN (2003)
    Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin
    Eur J Hum Genet, 11 (5), 416-9
    PubMed 12734548
  26. Stacy JE, Kausmally L, Simonsen B, Nordgard SH, Alsøe L, Michaelsen TE, Brekke OH (2003)
    Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries
    J Immunol Methods, 283 (1-2), 247-59
    PubMed 14659916
  27. Yoshimura N, Harada N, Bukholm I, Kåresen R, Børresen-Dale AL, Kristensen VN (2003)
    Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
    Breast Cancer Res, 6 (2), R46-55
    PubMed 14979917
  28. Aas T, Geisler S, Eide GE, Haugen DF, Varhaug JE, Bassøe AM, Thorsen T, Berntsen H, Børresen-Dale AL, Akslen LA, Lønning PE (2003)
    Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
    Eur J Cancer, 39 (4), 438-46
    PubMed 12751373

Publications 2002

  1. Allinen M, Launonen V, Laake K, Jansen L, Huusko P, Kääriäinen H, Børresen-Dale AL, Winqvist R (2002)
    ATM mutations in Finnish breast cancer patients
    J Med Genet, 39 (3), 192-6
    PubMed 11897822
  2. Bernstein JL, Seminara D, Børresen-Dale AL (2002)
    Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002
    Breast Cancer Res, 4 (6), 249-52
    PubMed 12473172
  3. Børresen AL (2002)
    Mismatch detection using heteroduplex analysis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.3
    PubMed 18428333
  4. Diep CB, Parada LA, Teixeira MR, Eknaes M, Nesland JM, Johansson B, Lothe RA (2002)
    Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis
    Genes Chromosomes Cancer, 36 (2), 189-97
    PubMed 12508247
  5. Jeffrey SS, Fero MJ, Børresen-Dale AL, Botstein D (2002)
    Expression array technology in the diagnosis and treatment of breast cancer
    Mol Interv, 2 (2), 101-9
    PubMed 14993355
  6. Kleivi K, Lothe RA, Heim S, Tsarouha H, Kraggerud SM, Pandis N, Papadopoulou A, Andersen J, Jakobsen KS, Teixeira MR (2002)
    Genome profiling of breast cancer cells selected against in vitro shows copy number changes
    Genes Chromosomes Cancer, 33 (3), 304-9
    PubMed 11807988
  7. Kraggerud SM, Aman P, Holm R, Stenwig AE, Fosså SD, Nesland JM, Lothe RA (2002)
    Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis
    Cancer Res, 62 (2), 512-7
    PubMed 11809703
  8. Kraggerud SM, Skotheim RI, Szymanska J, Eknaes M, Fosså SD, Stenwig AE, Peltomäki P, Lothe RA (2002)
    Genome profiles of familial/bilateral and sporadic testicular germ cell tumors
    Genes Chromosomes Cancer, 34 (2), 168-74
    PubMed 11979550
  9. Kringen P, Egedal S, Pedersen JC, Harbitz TB, Tveit KM, Berg K, Børresen-Dale AL, Andersen TI (2002)
    BRCA1 mutation screening using restriction endonuclease fingerprinting-single-strand conformation polymorphism in an automated capillary electrophoresis system
    Electrophoresis, 23 (24), 4085-91
    PubMed 12481264
  10. Kristiansen M, Langerød A, Knudsen GP, Weber BL, Børresen-Dale AL, Orstavik KH (2002)
    High frequency of skewed X inactivation in young breast cancer patients
    J Med Genet, 39 (1), 30-3
    PubMed 11826021
  11. Langerød A, Bukholm IR, Bregård A, Lønning PE, Andersen TI, Rognum TO, Meling GI, Lothe RA, Børresen-Dale AL (2002)
    The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas
    Cancer Epidemiol Biomarkers Prev, 11 (12), 1684-8
    PubMed 12496062
  12. Løvig T, Andersen SN, Thorstensen L, Diep CB, Meling GI, Lothe RA, Rognum TO (2002)
    Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis
    Br J Cancer, 87 (7), 756-62
    PubMed 12232760
  13. Løvig T, Meling GI, Diep CB, Thorstensen L, Norheim Andersen S, Lothe RA, Rognum TO (2002)
    APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status
    Scand J Gastroenterol, 37 (10), 1184-93
    PubMed 12408524
  14. Os I, Høieggen A, Larsen A, Sandset PM, Djurovic S, Berg K, Os A, Birkeland K, Westheim A (2002)
    Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
    J Intern Med, 253 (2), 232-9
    PubMed 12542565
  15. Passarino G, Cavalleri GL, Lin AA, Cavalli-Sforza LL, Børresen-Dale AL, Underhill PA (2002)
    Different genetic components in the Norwegian population revealed by the analysis of mtDNA and Y chromosome polymorphisms
    Eur J Hum Genet, 10 (9), 521-9
    PubMed 12173029
  16. Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO (2002)
    Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    Proc Natl Acad Sci U S A, 99 (20), 12963-8
    PubMed 12297621
  17. Skotheim RI, Monni O, Mousses S, Fosså SD, Kallioniemi OP, Lothe RA, Kallioniemi A (2002)
    New insights into testicular germ cell tumorigenesis from gene expression profiling
    Cancer Res, 62 (8), 2359-64
    PubMed 11956097
  18. Smiraglia DJ, Szymanska J, Kraggerud SM, Lothe RA, Peltomäki P, Plass C (2002)
    Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors
    Oncogene, 21 (24), 3909-16
    PubMed 12032829
  19. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
    Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    Oncogene, 21 (57), 8878-84
    PubMed 12483540
  20. Soucek P, Sarmanová J, Kristensen VN, Apltauerová M, Gut I (2002)
    Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas
    Int Arch Occup Environ Health, 75 Suppl, S86-92
    PubMed 12397416
  21. Zhao H, Hastie T, Whitfield ML, Børresen-Dale AL, Jeffrey SS (2002)
    Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis
    BMC Genomics, 3 (1), 31
    PubMed 12445333

Publications 2001

  1. Bjørheim J, Ekstrøm PO, Fossberg E, Børresen-Dale AL, Gaudernack G (2001)
    Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
    Biotechniques, 30 (5), 972-5
    PubMed 11355359
  2. Bomme L, Lothe RA, Bardi G, Fenger C, Kronborg O, Heim S (2001)
    Assessments of clonal composition of colorectal adenomas by FISH analysis of chromosomes 1, 7, 13 and 20
    Int J Cancer, 92 (6), 816-23
    PubMed 11351301
  3. Børresen-Dale AL, Hovig E, Smith-Sørensen B (2001)
    Detection of mutations by denaturing gradient gel electrophoresis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.5
    PubMed 18428306
  4. Dai H, Holm R, Kristensen GB, Abeler VM, Børresen-Dale AL, Helland A (2001)
    Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas
    Anal Cell Pathol, 23 (2), 45-9
    PubMed 11904459
  5. Fadl-Elmula I, Kytölä S, Pan Y, Lui WO, Derienzo G, Forsberg L, Mandahl N, Gorunova L, Bergerheim US, Heim S, Larsson C (2001)
    Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and FISH analysis
    Int J Cancer, 92 (6), 824-31
    PubMed 11351302
  6. Forus A, Sørlie T, Børresen-Dale AL, Myklebost O (2001)
    [Microarray technology--potential in cancer research]
    Tidsskr Nor Laegeforen, 121 (21), 2498-503
    PubMed 11875927
  7. Geisler S, Lønning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA, Børresen-Dale AL (2001)
    Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
    Cancer Res, 61 (6), 2505-12
    PubMed 11289122
  8. Gjertsen MK, Buanes T, Rosseland AR, Bakka A, Gladhaug I, Søreide O, Eriksen JA, Møller M, Baksaas I, Lothe RA, Saeterdal I, Gaudernack G (2001)
    Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
    Int J Cancer, 92 (3), 441-50
    PubMed 11291084
  9. Jain AN, Chin K, Børresen-Dale AL, Erikstein BK, Eynstein Lonning P, Kaaresen R, Gray JW (2001)
    Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival
    Proc Natl Acad Sci U S A, 98 (14), 7952-7
    PubMed 11438741
  10. Kristensen VN, Børresen-Dale AL, Kristensen T (2001)
    Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite ATAAA repeat
    Hum Mutat, 17 (3), 238-9
    PubMed 11241854
  11. Kristensen VN, Harada N, Kristensen T, Borresen-Dale AL (2001)
    [Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
    Vopr Onkol, 47 (2), 156-9
    PubMed 11383450
  12. Kristensen VN, Kelefiotis D, Kristensen T, Børresen-Dale AL (2001)
    High-throughput methods for detection of genetic variation
    Biotechniques, 30 (2), 318-22, 324, 326 passim
    PubMed 11233601
  13. Kristensen VN, Kure EH, Erikstein B, Harada N, Børresen-Dale A (2001)
    Genetic susceptibility and environmental estrogen-like compounds
    Mutat Res, 482 (1-2), 77-82
    PubMed 11535251
  14. Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL (2001)
    Microarrays in primary breast cancer--lessons from chemotherapy studies
    Endocr Relat Cancer, 8 (3), 259-63
    PubMed 11566617
  15. Minamoto T, Buschmann T, Habelhah H, Matusevich E, Tahara H, Boerresen-Dale AL, Harris C, Sidransky D, Ronai Z (2001)
    Distinct pattern of p53 phosphorylation in human tumors
    Oncogene, 20 (26), 3341-7
    PubMed 11423984
  16. Olsen JH, Hahnemann JM, Børresen-Dale AL, Brøndum-Nielsen K, Hammarström L, Kleinerman R, Kääriäinen H, Lönnqvist T, Sankila R, Seersholm N, Tretli S, Yuen J, Boice JD, Tucker M (2001)
    Cancer in patients with ataxia-telangiectasia and in their relatives in the nordic countries
    J Natl Cancer Inst, 93 (2), 121-7
    PubMed 11208881
  17. Salahshor S, Haixin L, Huo H, Kristensen VN, Loman N, Sjöberg-Margolin S, Borg A, Børresen-Dale AL, Vorechovsky I, Lindblom A (2001)
    Low frequency of E-cadherin alterations in familial breast cancer
    Breast Cancer Res, 3 (3), 199-207
    PubMed 11305955
  18. Salahshor S, Hou H, Diep CB, Loukola A, Zhang H, Liu T, Chen J, Iselius L, Rubio C, Lothe RA, Aaltonen L, Sun XF, Lindmark G, Lindblom A (2001)
    A germline E-cadherin mutation in a family with gastric and colon cancer
    Int J Mol Med, 8 (4), 439-43
    PubMed 11562785
  19. Sandvik AK, Støren O, Nørsett K, Laegreid A, Børresen-Dale AL, Myklebost O (2001)
    [Measurement of gene activity by DNA microarrays]
    Tidsskr Nor Laegeforen, 121 (10), 1225-8
    PubMed 11402749
  20. Sarmanová J, Benesová K, Gut I, Nedelcheva-Kristensen V, Tynková L, Soucek P (2001)
    Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas
    Hum Mol Genet, 10 (12), 1265-73
    PubMed 11406608
  21. Skotheim RI, Diep CB, Kraggerud SM, Jakobsen KS, Lothe RA (2001)
    Evaluation of loss of heterozygosity/allelic imbalance scoring in tumor DNA
    Cancer Genet Cytogenet, 127 (1), 64-70
    PubMed 11408068
  22. Skotheim RI, Kraggerud SM, Fosså SD, Stenwig AE, Gedde-Dahl T, Danielsen HE, Jakobsen KS, Lothe RA (2001)
    Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence
    Neoplasia, 3 (3), 196-203
    PubMed 11494113
  23. Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Lønning PE, Børresen-Dale AL (2001)
    Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    Proc Natl Acad Sci U S A, 98 (19), 10869-74
    PubMed 11553815
  24. Teixeira MR, Tsarouha H, Kraggerud SM, Pandis N, Dimitriadis E, Andersen JA, Lothe RA, Heim S (2001)
    Evaluation of breast cancer polyclonality by combined chromosome banding and comparative genomic hybridization analysis
    Neoplasia, 3 (3), 204-14
    PubMed 11494114
  25. Thorstensen L, Diep CB, Meling GI, Aagesen TH, Ahrens CH, Rognum TO, Lothe RA (2001)
    WNT1 inducible signaling pathway protein 3, WISP-3, a novel target gene in colorectal carcinomas with microsatellite instability
    Gastroenterology, 121 (6), 1275-80
    PubMed 11729105
  26. Thorstensen L, Qvist H, Nesland JM, Giercksky KE, Lothe RA (2001)
    Identification of two potential suppressor gene regions on chromosome arm 14q that are commonly lost in advanced colorectal carcinomas
    Scand J Gastroenterol, 36 (12), 1327-31
    PubMed 11761025
  27. Warren W, Hovig E, Smith-Sørensen B, Børresen AL, Fujimura FK, Liu Q, Feng J, Sommer SS (2001)
    Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
    Curr Protoc Hum Genet, Chapter 7, Unit 7.4
    PubMed 18428305

Publications 2000

  1. Fadl-Elmula I, Gorunova L, Mandahl N, Elfving P, Lundgren R, Mitelman F, Heim S (2000)
    Karyotypic characterization of urinary bladder transitional cell carcinomas
    Genes Chromosomes Cancer, 29 (3), 256-65
    PubMed 10992300
  2. Frengen E, Rocca-Serra P, Shaposhnikov S, Taine L, Thorsen J, Bepoldin C, Krekling M, Lafon D, Aas KK, El Monéim AA, Johansen H, Longy M, Prydz H, Dorion-Bonnet F (2000)
    High-resolution integrated map encompassing the breast cancer loss of heterozygosity region on human chromosome 16q22.1
    Genomics, 70 (3), 273-85
    PubMed 11161777
  3. Frengen E, Zhao B, Howe S, Weichenhan D, Osoegawa K, Gjernes E, Jessee J, Prydz H, Huxley C, de Jong PJ (2000)
    Modular bacterial artificial chromosome vectors for transfer of large inserts into mammalian cells
    Genomics, 68 (2), 118-26
    PubMed 10964509
  4. Helland A, Kraggerud SM, Kristensen GB, Holm R, Abeler VM, Huebner K, Borresen-Dale AL, Lothe RA (2000)
    Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival
    Int J Cancer, 88 (2), 217-22
    PubMed 11004671
  5. Hellström AC, Blegen H, Malec M, Silfverswärd C, Lystad S, Børresen-Dale AL, Auer G (2000)
    Recurrent fallopian tube carcinoma: TP53 mutation and clinical course
    Int J Gynecol Pathol, 19 (2), 145-51
    PubMed 10782411
  6. Hernandez AM, Fosså SD, Brøgger A, Kat A, Skovlund E (2000)
    Chromosome aberrations after etoposide containing cisplatin-based chemotherapy for malignant germ-cell tumours
    Ann Oncol, 11 (7), 897-8
    PubMed 10997823
  7. Jugessur A, Frost P, Andersen TI, Steine S, Lindblom A, Børresen-Dale AL, Eiken HG (2000)
    Enhanced detection of mutations in BRCA1 exon 11 using restriction endonuclease fingerprinting-single-strand conformation polymorphism
    J Mol Med (Berl), 78 (10), 580-7
    PubMed 11199332
  8. Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
    Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
    Biochem J, 352 Pt 3, 629-35
    PubMed 11104667
  9. Kraggerud SM, Szymanska J, Abeler VM, Kaern J, Eknaes M, Heim S, Teixeira MR, Tropé CG, Peltomäki P, Lothe RA (2000)
    DNA copy number changes in malignant ovarian germ cell tumors
    Cancer Res, 60 (11), 3025-30
    PubMed 10850452
  10. Kristensen VN, Borresen-Dale AL (2000)
    Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism
    Mutat Res, 462 (2-3), 323-33
    PubMed 10767642
  11. Liestøl K, Kvittingen EA, Rootwelt H, Dunlop O, Goplen AK, Pedersen JC, Brorson SH, Børresen-Dale AL, Myrvang B, Maehlen J (2000)
    Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome
    Cancer Detect Prev, 24 (5), 496-9
    PubMed 11129992
  12. Lothe RA, Smith-Sørensen B, Hektoen M, Stenwig AE, Mandahl N, Saeter G, Mertens F (2000)
    Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors
    Genes Chromosomes Cancer, 30 (2), 202-6
    PubMed 11135438
  13. Laake K, Jansen L, Hahnemann JM, Brondum-Nielsen K, Lönnqvist T, Kääriäinen H, Sankila R, Lähdesmäki A, Hammarström L, Yuen J, Tretli S, Heiberg A, Olsen JH, Tucker M, Kleinerman R, Børresen-Dale AL (2000)
    Characterization of ATM mutations in 41 Nordic families with ataxia telangiectasia
    Hum Mutat, 16 (3), 232-46
    PubMed 10980530
  14. Laake K, Vu P, Andersen TI, Erikstein B, Kåresen R, Lonning PE, Skovlund E, Børresen-Dale AL (2000)
    Screening breast cancer patients for Norwegian ATM mutations
    Br J Cancer, 83 (12), 1650-3
    PubMed 11104561
  15. Panagopoulos I, Isaksson M, Lindvall C, Björkholm M, Ahlgren T, Fioretos T, Heim S, Mitelman F, Johansson B (2000)
    RT-PCR analysis of the MOZ-CBP and CBP-MOZ chimeric transcripts in acute myeloid leukemias with t(8;16)(p11;p13)
    Genes Chromosomes Cancer, 28 (4), 415-24
    PubMed 10862050
  16. Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D (2000)
    Molecular portraits of human breast tumours
    Nature, 406 (6797), 747-52
    PubMed 10963602
  17. Stokke T, Galteland E, Holte H, Smedshammer L, Suo Z, Smeland EB, Børresen-Dale AL, DeAngelis P, Steen HB (2000)
    Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma
    Int J Cancer, 89 (4), 313-24
    PubMed 10956404
  18. Teixeira MR, Micci F, Dietrich CU, Heim S (2000)
    Detailed genome-wide screening for inter- and intrachromosomal abnormalities by sequential G-banding and RxFISH color banding of the same metaphase cells
    Cancer Genet Cytogenet, 119 (2), 94-101
    PubMed 10867142
  19. Teixeira MR, Waehre H, Lothe RA, Stenwig AE, Pandis N, Giercksky KE, Heim S (2000)
    High frequency of clonal chromosome abnormalities in prostatic neoplasms sampled by prostatectomy or ultrasound-guided needle biopsy
    Genes Chromosomes Cancer, 28 (2), 211-9
    PubMed 10825006
  20. Thorstensen L, Qvist H, Heim S, Liefers GJ, Nesland JM, Giercksky KE, Lothe RA (2000)
    Evaluation of 1p losses in primary carcinomas, local recurrences and peripheral metastases from colorectal cancer patients
    Neoplasia, 2 (6), 514-22
    PubMed 11228544